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REERTIGMSDLQSAIAEIKAAGRSKPRAGRDPVNQPMIHHWVDAIGDKNPIYVDDEAAKAAGHPGIVAPP AMIQVWTMGGLGQGRSDDDPLSKMMKLFDDAGYVGVVATNCEQTYHRYLQPGEEVTIAAELTDVIGPKQT ALGEGFFINQKITWQVGDEDVAEMMWRIMKFKPAERAKGAQVPEDLDPDKLMRPASSRDTQFFWDGVNAH ELRIQRRPDGTLQHPPVPAVWQSQDAPIDYAVASGNGTVYSYVVHHAPKVPGRTLPFVIALVELDEGVRM LGELRGVDPDQVEIGLPVRATYIDFPDSEVSPAWTLYAWEPVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5255 | - | - | 100% (324) | hypothetical protein Mvan_5255 |
| M. vanbaalenii PYR-1 | Mvan_4268 | - | 8e-13 | 34.09% (132) | hypothetical protein Mvan_4268 |
| M. vanbaalenii PYR-1 | Mvan_4171 | - | 4e-09 | 29.75% (121) | hypothetical protein Mvan_4171 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3572c | - | 1e-144 | 75.87% (315) | hypothetical protein Mb3572c |
| M. gilvum PYR-GCK | Mflv_1511 | - | 1e-161 | 84.49% (316) | hypothetical protein Mflv_1511 |
| M. tuberculosis H37Rv | Rv3542c | - | 1e-144 | 75.87% (315) | hypothetical protein Rv3542c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0616 | - | 1e-133 | 72.03% (311) | hypothetical protein MAB_0616 |
| M. marinum M | MMAR_5029 | - | 1e-148 | 77.07% (314) | hypothetical protein MMAR_5029 |
| M. avium 104 | MAV_0619 | - | 1e-146 | 76.83% (315) | hypothetical protein MAV_0619 |
| M. smegmatis MC2 155 | MSMEG_5992 | - | 1e-162 | 86.58% (313) | hypothetical protein MSMEG_5992 |
| M. thermoresistible (build 8) | TH_0364 | - | 1e-156 | 81.27% (315) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4103 | - | 1e-146 | 76.11% (314) | hypothetical protein MUL_4103 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3572c|M.bovis_AF2122/97 -----MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRN
Rv3542c|M.tuberculosis_H37Rv -----MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRN
MMAR_5029|M.marinum_M --------MSDIHEIVAQVKAAGPSKPRAGRDPVNQPMINNWVEAIGDQN
MUL_4103|M.ulcerans_Agy99 --------MSDIREIVAQVKAAGPSKPRAGRDPVNQPMINNWVEAIGDQN
MAV_0619|M.avium_104 --------MTDIAEAIAEIKAAGGPKPRAGRDPVNQPMINNWVEAIGDRN
Mflv_1511|M.gilvum_PYR-GCK -------MSADLQAGIEKITAAGRSEPRAGRDPVNQPMIHHWVDAIGDRN
MSMEG_5992|M.smegmatis_MC2_155 ---MTTQVNEDLQAGIEKIKAEGKSDPRKGRDPVNQPMIHHWVDAIGDKN
Mvan_5255|M.vanbaalenii_PYR-1 MREERTIGMSDLQSAIAEIKAAGRSKPRAGRDPVNQPMIHHWVDAIGDKN
TH_0364|M.thermoresistible__bu --------MSELQSAIDEIKAAGTSAPRKGRDPVNQPMIHHWVDAIGDRN
MAB_0616|M.abscessus_ATCC_1997 ------MSVVDIQEGFAKIKADGPSAPRLARDPVNQAMINNWVEAMGDRN
:: . ::.* * . ** .******.**::**:*:**:*
Mb3572c|M.bovis_AF2122/97 PIYVDDAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFD
Rv3542c|M.tuberculosis_H37Rv PIYVDDAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFD
MMAR_5029|M.marinum_M PIYADDAAARAVGHPGIVAPPAMIQVWTMMGLGGVRADDDPLPPIIKLFD
MUL_4103|M.ulcerans_Agy99 PIYADDPAARAVGHPGIVAPPAMIQVWTMMGLSGVRADDDPLPPIIKLFD
MAV_0619|M.avium_104 PIYVDEAAARAVGHPGIVAPPAMIQVWTMFGLGGERPKDDPMGPIMELFD
Mflv_1511|M.gilvum_PYR-GCK PIYVDDEAARAAGHPGIVAPPAMIQVWTMGGLGQGRSDDDPLSKIMELFD
MSMEG_5992|M.smegmatis_MC2_155 PIYVDQEAAKAAGHPGIVAPPAMIQVWTMGGLGAGRSDDDPLSKIMKLFD
Mvan_5255|M.vanbaalenii_PYR-1 PIYVDDEAAKAAGHPGIVAPPAMIQVWTMGGLGQGRSDDDPLSKMMKLFD
TH_0364|M.thermoresistible__bu PIYVDDEAARAVGHPGVVAPPAMIQVWTMGGLGEGRPDDDPLSKMMRLFD
MAB_0616|M.abscessus_ATCC_1997 PIYVDEEAAKAAGHPGIVAPPAMAQVWTMAGLYGERSGDDPLGRVMALLD
***.*: **:*.****:****** ***** ** *. ***: :: *:*
Mb3572c|M.bovis_AF2122/97 DAGYIGVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFIN
Rv3542c|M.tuberculosis_H37Rv DAGYIGVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFIN
MMAR_5029|M.marinum_M DAGYIGVVATNCEQTYHRYLQPGELVSISAELGDVVGPKQTALGEGWFIN
MUL_4103|M.ulcerans_Agy99 DAGYIGVVATNCEQTYHRYLQLGELVSISAELGDVVGPKQTALGEGWFIN
MAV_0619|M.avium_104 NAGYVGVVATNCEQTYHRYLRPGEQVSITSEMGDVIGPKQTALGEGWFIN
Mflv_1511|M.gilvum_PYR-GCK EAGYVGVVATNCEQTYHRYLQPGEELTIHADITDVVGPKQTALGEGFFIN
MSMEG_5992|M.smegmatis_MC2_155 DAGYVGVVATNCEQTYHRYLQPGEELTIHAEITDVVGPKQTALGEGYFIN
Mvan_5255|M.vanbaalenii_PYR-1 DAGYVGVVATNCEQTYHRYLQPGEEVTIAAELTDVIGPKQTALGEGFFIN
TH_0364|M.thermoresistible__bu DAGFVGVVATNCDQTYHRYLRPGEEVTINAEITDVIGPKQTALGEGYFIN
MAB_0616|M.abscessus_ATCC_1997 SAGYESVVATNYEQIYHRYLELGEQVTTTNEVTEVFGPKQTALGESWFIN
.**: .***** :* ***** ** :: :: :*.*********.:***
Mb3572c|M.bovis_AF2122/97 QHIVWQVGD-EDVAEMNWRILKFKP---AGSPSSVPDDLDPDAMMRPSSS
Rv3542c|M.tuberculosis_H37Rv QHIVWQVGD-EDVAEMNWRILKFKP---AGSPSSVPDDLDPDAMMRPSSS
MMAR_5029|M.marinum_M QHIIWQVGD-EDVAEMNWRILKFKPR-AESAPTNVPDDLDPDAMMRPSSS
MUL_4103|M.ulcerans_Agy99 QHIIWQVGD-EDVAEMNWRILKFKPR-TESAPTNVPDDLDPDAMMRPSSS
MAV_0619|M.avium_104 QHIIWRVGD-EDVAEMNWRILKFRPRESDAAASPVPDDLDPATMMRPASS
Mflv_1511|M.gilvum_PYR-GCK QLITWTVGDGETVAEMNWRIMKFKPR-AEDK-PPVPEDLDPDKLMRPASS
MSMEG_5992|M.smegmatis_MC2_155 QLITWTTEEGEAVAEMNWRIMKFKPR-EDQK-PAVPDDLDPDKLMRPASS
Mvan_5255|M.vanbaalenii_PYR-1 QKITWQVGD-EDVAEMMWRIMKFKPA-ERAKGAQVPEDLDPDKLMRPASS
TH_0364|M.thermoresistible__bu QHITWQVDGGETVAEMDWRIMKFRPR-EKTTGPVVPDDLDPEKLMRPAPS
MAB_0616|M.abscessus_ATCC_1997 IHAEWHVGD-ELVNEMNWRIMKFRPG--AKKAADVPQDLDPSKLMRPSWS
* . * * ** ***:**:* . **:**** :***: *
Mb3572c|M.bovis_AF2122/97 RDTAFFWDGVKAHELRIQRLADGSLRHPPVPAVWQDKSVPINYVVSSGRG
Rv3542c|M.tuberculosis_H37Rv RDTAFFWDGVKAHELRIQRLADGSLRHPPVPAVWQDKSVPINYVVSSGRG
MMAR_5029|M.marinum_M RDTAFFWDGVKAHELRIQRRPDGSLQHPPVPAVWQDKAEPIDYVVSTGTG
MUL_4103|M.ulcerans_Agy99 RDTAFFWDGVKAHELRIQRRPDGSLQHPPLPAVWQDKAEPIDYVVSIGTG
MAV_0619|M.avium_104 RDTAFFWEGVKAHELRIQRRPDGSLQHPPVPAVWQDKTAPIDYVVASGKG
Mflv_1511|M.gilvum_PYR-GCK KDTRFFWDGVNAHELRIQRRPDGSLQHPPVPAVWADKDAPTDYVVASGNG
MSMEG_5992|M.smegmatis_MC2_155 RDTQFFWDGVNAHELRIQRRPDGTLQHPPVPAVWQDKEQPIDYVVASGNG
Mvan_5255|M.vanbaalenii_PYR-1 RDTQFFWDGVNAHELRIQRRPDGTLQHPPVPAVWQSQDAPIDYAVASGNG
TH_0364|M.thermoresistible__bu RDTQFFWDGVNAHELRIQRLPDGTLQHPPVPAVWQDKSEEVDYVVAGGRG
MAB_0616|M.abscessus_ATCC_1997 RDSAYFWEGVAAHELRLQKRPDGSLQHPPVPAVWQDKEAPIEYQVASGRG
:*: :**:** *****:*: .**:*:***:**** .: :* *: * *
Mb3572c|M.bovis_AF2122/97 TVFSFVVHHAPKVPGRTVPFVIALVELEEGVRMLGELRGADPARVAIGMP
Rv3542c|M.tuberculosis_H37Rv TVFSFVVHHAPKVPGRTVPFVIALVELEEGVRMLGELRGADPARVAIGMP
MMAR_5029|M.marinum_M TVFSFVVHHAPKVPGRTLPFVIALVELDEGVRMLGELRNVEPEQVEIGMP
MUL_4103|M.ulcerans_Agy99 TVFSFVVHHAPKVPGRTLPFVIALVELDEGVRMLGELRNVEPEQVEIGMP
MAV_0619|M.avium_104 TVYSFVVHHAPKVPGRTLPFVIALVELAEGVRMLGELRGIDPARVRIGLP
Mflv_1511|M.gilvum_PYR-GCK TVFSFVVHHAPQVPGRSLPFVIALVELDEGVRMLGELRNVDPADVQIGMP
MSMEG_5992|M.smegmatis_MC2_155 TVFSYVVHHAPKVPGRTLPFVIALVELEEGVRMLGELRNVDPDQVQIGMP
Mvan_5255|M.vanbaalenii_PYR-1 TVYSYVVHHAPKVPGRTLPFVIALVELDEGVRMLGELRGVDPDQVEIGLP
TH_0364|M.thermoresistible__bu TVFSFVVHHAPKVPGRTLPFVIALVELDEGVRMLGELRNVDPAAVQIGMP
MAB_0616|M.abscessus_ATCC_1997 TVYSYVVHHAPQVPGRTLPFVIALVELDEGVRMLGELRGVSPDDVQIGLP
**:*:******:****::********* **********. .* * **:*
Mb3572c|M.bovis_AF2122/97 VRATYIDFP------DWSLYAWEPDE
Rv3542c|M.tuberculosis_H37Rv VRATYIDFP------DWSLYAWEPDE
MMAR_5029|M.marinum_M VRTVYIDFPAGASGPEWTLYAWEPDA
MUL_4103|M.ulcerans_Agy99 VRTVYIDFPAGASGPEWTLYAWEPDA
MAV_0619|M.avium_104 VRATYLDFPADDNGPEWSLYAWEPDA
Mflv_1511|M.gilvum_PYR-GCK VRATYLDFPDSDVSPAWTLYAWEPAR
MSMEG_5992|M.smegmatis_MC2_155 VRATFIDFPDSEISPAWTLYAWEPRA
Mvan_5255|M.vanbaalenii_PYR-1 VRATYIDFPDSEVSPAWTLYAWEPVR
TH_0364|M.thermoresistible__bu VRVMFIDLPETESGPSWTLYAWEPDT
MAB_0616|M.abscessus_ATCC_1997 VRATYLDFPAEGEDPAWTLYAWEAA-
**. ::*:* *:*****.