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DALLAWVRRQINHTFFNKTPVYGPISTEQILTGQLLIDLHASDPNGDPLTYDIIQPEHGWVFRDLITGRF VYTPDELVAGDPLVDSFQVVIRDDSEHLSGTLGSIQKLLHGVARLFGLAQADNVTVTVPVFVDPVIQLPP LITPIAGPGYTLGGDPVKLVSSVLVADGDSDELSQVVIKIATLGQDGDLLEYVAPQGNPITATWDAQTMT LTLSGVATTAQYQQAIEAVTFSATDGALLVRGVTLSATDEHGVDNIAPGFVAVGVWPAIKLPPLVTPLPG LGYTIGDDPVKLVSAVDIADGDSDYLSKLVLKIATLAQSGDVLSYVAPSDNPITATWDAGAKTLTLSGVA TKAQYEEALMAVTFSATEGALLVRGVTMSATDADGVENIAPGLVTVGVWPALALPPLVTPVPGLGYTLAD DPVKLVSAVDIADGDSDYLSEAILKIATLAQSGDVLGYVAPSGNPITATWDAGARTLTLSGVATKAQYEE ALKAVTFSATQGALLVRGVTISVTDADGVENIAPGLVTVGVWLATQLPPLVTPVGAPTYTLGSTPVKLVS AVDIADGDSDFLSEAVLRIALLAQSGDALGYVAPSGNPITATWDAGARTLTLSGVATKAQYEEALKAVTF SATQGVGIVRTITIDVTDDTGVQSLTSGLVLAGARWSLPPLVTPVGAPTYTLGSTPVKLVSAVDIADGDS DFLSEAVLRIALLAQSGDALGYVAPSGNPITATWDAGARTLTLSGVATKAQYEEALKAVTFSATQGVGIV RTITIDVTDDTGVQSLTSGLVLAGARNPLPPLVTPFGGRSYTIGNQPVKPVAAVDIVDADSDYLTSATVE VTLFGRSGDVLQFNGLAGVPISGSYDAGSRTLTLTGTATKAQYEAALKAITFTATGGAWTTRTLAIRVTD DAGVRSSAGLLTLSVW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5058 | - | - | 100% (927) | hypothetical protein Mvan_5058 |
| M. vanbaalenii PYR-1 | Mvan_5057 | - | 0.0 | 58.73% (916) | hypothetical protein Mvan_5057 |
| M. vanbaalenii PYR-1 | Mvan_2332 | - | 5e-13 | 36.42% (162) | hypothetical protein Mvan_2332 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0912 | - | 2e-05 | 29.59% (169) | hypothetical protein Mb0912 |
| M. gilvum PYR-GCK | Mflv_1698 | - | 1e-172 | 45.35% (807) | hypothetical protein Mflv_1698 |
| M. tuberculosis H37Rv | Rv0888 | - | 2e-05 | 29.59% (169) | hypothetical protein Rv0888 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4644 | - | 5e-07 | 27.98% (168) | hypothetical protein MMAR_4644 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0912|M.bovis_AF2122/97 --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4644|M.marinum_M --------------------------------------------------
Mvan_5058|M.vanbaalenii_PYR-1 ------------------------------MDALLAWVRRQINHTFFNKT
Mflv_1698|M.gilvum_PYR-GCK MSEQPSRRPVTQGGTRPAMYIGRVGALAVSLGIGFAVANAATGFAYADTD
Mb0912|M.bovis_AF2122/97 --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4644|M.marinum_M --------------------------------------------------
Mvan_5058|M.vanbaalenii_PYR-1 -----PVYGPISTEQILTGQLLIDLHAS------------------DPNG
Mflv_1698|M.gilvum_PYR-GCK GDSGGSVSASAPATRAESGKPASGLSTDRGQTTSPSGGATGAAGDGESDG
Mb0912|M.bovis_AF2122/97 --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4644|M.marinum_M --------------------------------------------------
Mvan_5058|M.vanbaalenii_PYR-1 DP-------LTYDIIQPEHGWVFRDLITGRFVYTPDELVAGDP-------
Mflv_1698|M.gilvum_PYR-GCK DDDPAPSGRTTTDDDAAEAEALSRDADSAADDSTADDSADADAEESGDAE
Mb0912|M.bovis_AF2122/97 --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4644|M.marinum_M --------------------------------------------------
Mvan_5058|M.vanbaalenii_PYR-1 ------------------LVDSFQVVIRDDSEHLSGTLGSIQKLLHGVAR
Mflv_1698|M.gilvum_PYR-GCK DVSAAEDDTDDTPAPTGEAEATPDVATRAQQKPTTPVRTTTATTVSGASA
Mb0912|M.bovis_AF2122/97 --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4644|M.marinum_M --------------------------------------------------
Mvan_5058|M.vanbaalenii_PYR-1 LFGLAQADNVTVTVPVFVDPVIQ--LPPLITPIAGPGYTLGGDPVKLVS-
Mflv_1698|M.gilvum_PYR-GCK EAAPQTPETGTVTSANVLSAVVSTAVAPLADPELPAPSPVADAVLAWVRR
Mb0912|M.bovis_AF2122/97 --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4644|M.marinum_M --------------------------------------------------
Mvan_5058|M.vanbaalenii_PYR-1 ---------SVLVADGDSDELS--QVVIKIATLGQDGDLLEYVAPQGNP-
Mflv_1698|M.gilvum_PYR-GCK LITHTFFNKTPVVRSVETEQILTGQVLITIDAYDPNGDPLTYEIVQPDTG
Mb0912|M.bovis_AF2122/97 --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4644|M.marinum_M --------------------------------------------------
Mvan_5058|M.vanbaalenii_PYR-1 ----ITAT-WDAQTMTLTLSGVATTAQYQQAI--EAVTFSATDGALLVRG
Mflv_1698|M.gilvum_PYR-GCK LVVRVPATNTFLYTPTLPVLGDPVPVSFDVVIRDDSEHLTGVLGGIQNLL
Mb0912|M.bovis_AF2122/97 ---------------------------------------MDYAKRIGQVG
Rv0888|M.tuberculosis_H37Rv ---------------------------------------MDYAKRIGQVG
MMAR_4644|M.marinum_M ---------------------------------------MGYASHAVRVG
Mvan_5058|M.vanbaalenii_PYR-1 VTLSATDEHGVDNIAPGFVAVGVWPAIKLPP-LVTPLPGLGYTIGDDPVK
Mflv_1698|M.gilvum_PYR-GCK HAVARFFRLAQPDNYTQTVAFDAEPIVAVPPTLAVTGRLLPYLVGADPVN
: * *
Mb0912|M.bovis_AF2122/97 ALAVVLGVG--------------AAVTT-HAIGSAAPTDPSSSSTDSPVD
Rv0888|M.tuberculosis_H37Rv ALAVVLGVG--------------AAVTT-HAIGSAAPTDPSSSSTDSPVD
MMAR_4644|M.marinum_M ALVFVLVVG--------------AAVATDQAIGHAAPTDSDASNGESWAD
Mvan_5058|M.vanbaalenii_PYR-1 LVSAVDIADGDSDYLSKLVLKIATLAQSGDVLSYVAPSDNPITATWDAGA
Mflv_1698|M.gilvum_PYR-GCK LLSLAKIVDLDSPQMSEATVTIGVGRQDGDQLRYVAPEGVTIDVEQVN-D
: . .. . . : .** .
Mb0912|M.bovis_AF2122/97 ACSPLGG----------------------------SASSLA---------
Rv0888|M.tuberculosis_H37Rv ACSPLGG----------------------------SASSLA---------
MMAR_4644|M.marinum_M VPAPPGGEN-------------------------IAASLLPGAAQPGAVP
Mvan_5058|M.vanbaalenii_PYR-1 KTLTLSGVATKAQYEEALMAVTFSATEGALLVRGVTMSATDADGVENIAP
Mflv_1698|M.gilvum_PYR-GCK HTLKLTGLASQADYEKALMAITFSTTDLGLVARTVDFTITDEHGESNLVP
* :
Mb0912|M.bovis_AF2122/97 ------------AIPGASVPQVGVR------------QVDPGSIPDDLLN
Rv0888|M.tuberculosis_H37Rv ------------AIPGASVPQVGVR------------QVDPGSIPDDLLN
MMAR_4644|M.marinum_M GAALPGTALPGTALPGAASPGMGTP------------QLDPSNIPDDLLN
Mvan_5058|M.vanbaalenii_PYR-1 GLVTVGVW-PALALPPLVTPVPGLGYTLADDPVKLVSAVDIADGDSDYLS
Mflv_1698|M.gilvum_PYR-GCK AFSLVTVLGLPVDAPPSLLAAGGLPYFLGGAPVPLLSLAQIVDVDSASMQ
* . * : . . :.
Mb0912|M.bovis_AF2122/97 ALIDFLAAVRNGLVPIIENRTPVANPQQVSVPEGGTVGPVRFDACDPDGN
Rv0888|M.tuberculosis_H37Rv ALIDFLAAVRNGLVPIIENRTPVANPQQVSVPEGGTVGPVRFDACDPDGN
MMAR_4644|M.marinum_M AVINFLASIRNGVVPILENRTPVATPQQLEIDVNGSTGLVPFSAYDPDGN
Mvan_5058|M.vanbaalenii_PYR-1 EAILKIATLAQ-SGDVLGYVAPSGNPITATWDAGARTLTLSGVATKAQYE
Mflv_1698|M.gilvum_PYR-GCK RVLVAMSALTRVAGDKLGYVAPAG-ITVGVNQVDDWTIELTGVHSRADYE
: :::: . : :* . . . : .: :
Mb0912|M.bovis_AF2122/97 RMTFAVRERGAPGGPQHGIVTVDQRTASFIYTADPGFVGTDTFS------
Rv0888|M.tuberculosis_H37Rv RMTFAVRERGAPGGPQHGIVTVDQRTASFIYTADPGFVGTDTFS------
MMAR_4644|M.marinum_M RMTFKVNPRGTPGGPQHGMVNIDESRAAFVYTPEPNFVGIDTFT------
Mvan_5058|M.vanbaalenii_PYR-1 EALKAVTFSATQGALLVRGVTISVTDADGVENIAPGLVTVGVW--LATQL
Mflv_1698|M.gilvum_PYR-GCK TALRAITFSAESLGLLARTVEISLTDADGNNSLTPTLVAATVLPGVDVEL
: . . * :. * . * :* .
Mb0912|M.bovis_AF2122/97 ------------------------VNVSDDTSLHVHGLAGYLGPFHGHDD
Rv0888|M.tuberculosis_H37Rv ------------------------VNVSDDTSLHVHGLAGYLGPFHGHDD
MMAR_4644|M.marinum_M ------------------------VAVSDDTSLHVHGLAGYLGPFHGHDD
Mvan_5058|M.vanbaalenii_PYR-1 PPLVTPVGAPTYTLGSTPVKLVSAVDIADGDSDFLSEAVLRIALLAQSGD
Mflv_1698|M.gilvum_PYR-GCK PLIVTPVGLPVHTIGKAPVKLLTSVGIANADDDQLTGAVVSIGLNRVAGD
* ::: . : . :. .*
Mb0912|M.bovis_AF2122/97 VATVTVFVGNTPTDTISGDFSMLTYNIAGLPFPLSSAILPRFFYTKEIGK
Rv0888|M.tuberculosis_H37Rv VATVTVFVGNTPTDTISGDFSMLTYNIAGLPFPLSSAILPRFFYTKEIGK
MMAR_4644|M.marinum_M VATVTIFVGNIPTGTISGDFSMLTYNIAGLPFPLSSAMLPRFLYTKEIGK
Mvan_5058|M.vanbaalenii_PYR-1 ALGYVAPSGNPITATWDAGARTLTLSGVATKAQYEEALKAVTFSATQGVG
Mflv_1698|M.gilvum_PYR-GCK TLGYVAVEGNPITVQQTN-AWTLTLSGTGTVEQYQQALQSITFSATA-LG
. . ** * ** . .. ..*: . : :.
Mb0912|M.bovis_AF2122/97 RLNAYYVANVQED--FAYHQFLIKKSKMPSQTPPEPPTLLWPIGVPFSDG
Rv0888|M.tuberculosis_H37Rv RLNAYYVANVQED--FAYHQFLIKKSKMPSQTPPEPPTLLWPIGVPFSDG
MMAR_4644|M.marinum_M RLNNFSVSNVQED--FSYHEFLIKKSRMPSQTPPSPPTLLWPIGVPFSDG
Mvan_5058|M.vanbaalenii_PYR-1 IVRTITIDVTDDTGVQSLTSGLVLAGARWSLPP-LVTPVGAPTYTLGSTP
Mflv_1698|M.gilvum_PYR-GCK LPRTVTITVTESDGDTNPAPGIVFANSLAPLRPTIVVTAVPPTHTIGRPG
. : .:. :: . . * . * .
Mb0912|M.bovis_AF2122/97 LNTLSEFKVQRLDRQTWYECTSDNCLTLKGFTYSQMRLPGGD----TVDV
Rv0888|M.tuberculosis_H37Rv LNTLSEFKVQRLDRQTWYECTSDNCLTLKGFTYSQMRLPGGD----TVDV
MMAR_4644|M.marinum_M LNSLAVFKVKRLDRQTWFQCDADNCLTPKGFSYSQLQLPGGN----TMDL
Mvan_5058|M.vanbaalenii_PYR-1 VKLVSAVDIADGDSDFLSEAVLRIALLAQSGDALGYVAPSGNPITATWDA
Mflv_1698|M.gilvum_PYR-GCK VVIAPVVTIEDLDSPVLTGATVALGVGRQVGDVLAYAPPTPGLITASWN-
: . . : * . : : * . : :
Mb0912|M.bovis_AF2122/97 YNLHTNTGGGPTTNANLAQVANYIQQNSAGRAVIVTGDFNARYSDDQSAL
Rv0888|M.tuberculosis_H37Rv YNLHTNTGGGPTTNANLAQVANYIQQNSAGRAVIVTGDFNARYSDDQSAL
MMAR_4644|M.marinum_M YNLHANTGGGVLTNANLRQLANYILQNSAGRAVIVTGDFNALYSEDQAGL
Mvan_5058|M.vanbaalenii_PYR-1 GARTLTLSGVATKAQYEEALKAVTFSATQGVGIVRTITIDVTDDTGVQSL
Mflv_1698|M.gilvum_PYR-GCK GTDTLTLSGPASVAEYEAALEAVTFSATGGAGVPRTVTINVVDDSGLSAV
. .* : . : * .: * ::. . . .:
Mb0912|M.bovis_AF2122/97 LQFAQVNGLTDAWVQVEH------------GPTTPPFAPTCMVGNECELL
Rv0888|M.tuberculosis_H37Rv LQFAQVNGLTDAWVQVEH------------GPTTPPFAPTCMVGNECELL
MMAR_4644|M.marinum_M LDFAGSTGLTDAWVEVEH------------GPTTPPFAPDCMVGNECELL
Mvan_5058|M.vanbaalenii_PYR-1 TSGLVLAGARNPLPPLVTPFGG--RSYTIGNQPVKPVAAVDIVDADSDYL
Mflv_1698|M.gilvum_PYR-GCK LPGAAAALVKNPDRPTVVTVGLPDLSFPSVGDTVTPITSATIVDTDSSVL
:. . .. *.:. :*. :.. *
Mb0912|M.bovis_AF2122/97 D------KIFYRSGQGVTLQAVSYGNEAPKFFNSKGEPLSDHSPAVVGFH
Rv0888|M.tuberculosis_H37Rv D------KIFYRSGQGVTLQAVSYGNEAPKFFNSKGEPLSDHSPAVVGFH
MMAR_4644|M.marinum_M D------KIFYRSGTGVTLQATAYSNEAPNFNNSNGQPLSDHSPPAVAFH
Mvan_5058|M.vanbaalenii_PYR-1 TSATVEVTLFGRSGDVLQFNGLAGVPISGSYDAGSRTLTLTGTATKAQYE
Mflv_1698|M.gilvum_PYR-GCK SGASVRISERFTTGDTLAYAAVAGVPIAATFDSATGLLTLTGTATIAQYK
. :* : . : : .: .. :.. . :.
Mb0912|M.bovis_AF2122/97 YVADNVAVR-----------------------------------------
Rv0888|M.tuberculosis_H37Rv YVADNVAVR-----------------------------------------
MMAR_4644|M.marinum_M YETTNVSYPN----------------------------------------
Mvan_5058|M.vanbaalenii_PYR-1 AALKAITFTAT--GG-----AWTTRTLAIRVTDDAGVR-SSAGLLTLSVW
Mflv_1698|M.gilvum_PYR-GCK QALQSITFRATRYGGGLLDVIGVTRTLSVYVTDDTGVSNTLPGVVAVTVF
::
Mb0912|M.bovis_AF2122/97 -
Rv0888|M.tuberculosis_H37Rv -
MMAR_4644|M.marinum_M -
Mvan_5058|M.vanbaalenii_PYR-1 -
Mflv_1698|M.gilvum_PYR-GCK R