For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TRVRWLQAIAVIGATALLMASSCSWQIGIPVPDGVPPPPGDAVPQIDTYAKGRPADQLHEWAAERAPALG IPVTALEAYAYAARVAEVENPDCNLKWTTLAGIGQVESHHGTYRGSTVAADGEVTPPIRGVLLDGTAGNL VILDDDSVSHDPAIENKGDEPFARAMGPMQFIPETWRLYGVDANNDGDVSADNIDDAALSAAGYLCWRGK DLSKPRGWMEALRAYNHSDQYARTVRDWATAYAQGHPL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4772 | - | - | 100% (249) | putative lipoprotein LpqU |
| M. vanbaalenii PYR-1 | Mvan_3717 | - | 6e-95 | 68.31% (243) | putative lipoprotein LpqU |
| M. vanbaalenii PYR-1 | Mvan_4490 | - | 1e-28 | 42.70% (178) | lytic transglycosylase, catalytic |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1050 | lpqU | 1e-104 | 73.06% (245) | putative lipoprotein LpqU |
| M. gilvum PYR-GCK | Mflv_1953 | - | 1e-136 | 91.97% (249) | putative lipoprotein LpqU |
| M. tuberculosis H37Rv | Rv1022 | lpqU | 1e-103 | 72.65% (245) | lipoprotein LpqU |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1164 | - | 3e-79 | 60.00% (250) | putative lipoprotein LpqU |
| M. marinum M | MMAR_4463 | lpqU | 1e-105 | 73.06% (245) | lipoprotein LpqU |
| M. avium 104 | MAV_1163 | - | 1e-103 | 70.61% (245) | LpqU protein |
| M. smegmatis MC2 155 | MSMEG_5416 | - | 1e-102 | 76.52% (230) | LpqU protein |
| M. thermoresistible (build 8) | TH_0916 | - | 6e-96 | 78.04% (214) | LpqU protein |
| M. ulcerans Agy99 | MUL_4632 | lpqU | 1e-105 | 72.65% (245) | lipoprotein LpqU |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1050|M.bovis_AF2122/97 MS-------PRRWLRAVAVIGATAMLLASSCTWQLS--LFIPDGVPPPPG
Rv1022|M.tuberculosis_H37Rv MS-------PRRWLRAVAVIGATAMLLASSCTWQLS--LFITDGVPPPPG
MMAR_4463|M.marinum_M MS-------PRRWLRAAAVIGATAMLLASSCTWQLS--LFIPEGVPPPPG
MUL_4632|M.ulcerans_Agy99 MS-------PRRWLRAAAVIGATAMLLASSCTWQLS--LFIPEGVPPPPG
MAV_1163|M.avium_104 MS-------PRRWMRAAAVIGATAIVLASSCTWQLS--LFIPDGVPPPAG
Mvan_4772|M.vanbaalenii_PYR-1 MT-------RVRWLQAIAVIGATALLMASSCSWQIG--IPVPDGVPPPPG
Mflv_1953|M.gilvum_PYR-GCK MT-------RVRWLQAMAVIGATALLMASSCSWQMG--IRVPDGVPPPAG
MSMEG_5416|M.smegmatis_MC2_155 --------------------------MASSCSWQLG--TPIPEGVPPPAG
TH_0916|M.thermoresistible__bu --------------------------------------------VPPPAG
MAB_1164|M.abscessus_ATCC_1997 MSSVAVRSLPARFGRIMLVVSISVFLLAAGCSWQLGGRNPLPQGVPPPAG
****.*
Mb1050|M.bovis_AF2122/97 DPVPPVDT---HAGGRPADQLREWAEKRAAALGIPVIALEAYAYAARVAE
Rv1022|M.tuberculosis_H37Rv DPVPPVDT---HAGGRPADQLREWAEKRAAALGIPVIALEAYAYAARVAE
MMAR_4463|M.marinum_M DPVPPVDT---YASGRPADQLREWAEQRAPALEMPVIALEAYAYAARVAE
MUL_4632|M.ulcerans_Agy99 DPVPPVDT---YASGRPADQLREWAEQRAPALEMPVIALEAYTYAARVAE
MAV_1163|M.avium_104 DPVPPVDT---HASGRPADQLHDWAAQRAAGLEIPVIALEAYAYAARVAE
Mvan_4772|M.vanbaalenii_PYR-1 DAVPQIDT---YAKGRPADQLHEWAAERAPALGIPVTALEAYAYAARVAE
Mflv_1953|M.gilvum_PYR-GCK DAVPQIDT---YAKGRPADQLHDWAAERAPALRIPVTALEAYAYAARVAE
MSMEG_5416|M.smegmatis_MC2_155 DPVPAIDT---YAKGRPADALREWAAERAPALGIPVKALEAYAYAARVAE
TH_0916|M.thermoresistible__bu DPVPAIDI---YVEGRPADQLHEWAAERAPKLGIPVTALEAYAYAARVAE
MAB_1164|M.abscessus_ATCC_1997 DPVPDIATPPAHIQGRPADQLREWSTPRAEKTGIPVIALEAYAYAAKVAE
*.** : : ***** *::*: ** :** *****:***:***
Mb1050|M.bovis_AF2122/97 VENPKCHLAWTTLAGIGRVESHHGTYRGATIAPNGDVSPPIRGVRLDGTG
Rv1022|M.tuberculosis_H37Rv VENPKCHLAWTTLAGIGRVESHHGTYRGATIAPNGDVSPPIRGVRLDGTG
MMAR_4463|M.marinum_M VENPKCHIAWTTLAGIGQVESHNGTYRGATIAPNGDVRPPIRGVRLDGTG
MUL_4632|M.ulcerans_Agy99 VENPKCHIAWTTLAGIGQVESHNGTYRGATIAPNGDVRPPIRGVRLDGTG
MAV_1163|M.avium_104 VENPKCHIAWTTLAGIGQVESHHGTYRGARLAPNGDVSPPIRGVRLDGSG
Mvan_4772|M.vanbaalenii_PYR-1 VENPDCNLKWTTLAGIGQVESHHGTYRGSTVAADGEVTPPIRGVLLDGTA
Mflv_1953|M.gilvum_PYR-GCK VENPDCNLKWTTLAGIGQVESHHGTYRGATIARDGEVTPPIRGVLLDGTN
MSMEG_5416|M.smegmatis_MC2_155 VENPNCNLKWTTLAGIGMVESHHGTYRGAMITQNSDVSPPIRGVLLDGTA
TH_0916|M.thermoresistible__bu VVNPKCKITWTTLAGIGMVESHHGTYRGAMVATDGNVTPPIRGMRLDGSA
MAB_1164|M.abscessus_ATCC_1997 RENPRCKIAWTTLAGIGTVESHNGTYHGAELQPNGDALPPIRGVRLDGSN
** *:: ******** ****:***:*: : :.:. *****: ***:
Mb1050|M.bovis_AF2122/97 GTLRIVDRDGGGLD------GDAAVERAMGPMQFISETWRLYGVAARNDG
Rv1022|M.tuberculosis_H37Rv GTLRIVDRDGGGLD------GDAAVERAMGPMQFISETWRLYGVAARNDG
MMAR_4463|M.marinum_M GTLRIVDSERANLD------GDDGVERAMGPMQFISETWRLYGVDANNDG
MUL_4632|M.ulcerans_Agy99 GTLRIVDSERANLD------GDDGVERAMGPMQFISETWRLYGVDANNDG
MAV_1163|M.avium_104 GTLRIVDND-EDVT------DEDGVTRAMGPMQFIPETWRLYAVDAHNDG
Mvan_4772|M.vanbaalenii_PYR-1 GNLVILDDDSVSHDPAIENKGDEPFARAMGPMQFIPETWRLYGVDANNDG
Mflv_1953|M.gilvum_PYR-GCK GNLEILDGDAVSHDPAVEAKGDEPFARAMGPMQFIPETWRLYGVDANNDG
MSMEG_5416|M.smegmatis_MC2_155 GNMRIADTDGGLLD------GDDELDRAMGPMQFIPETWGHFGVDANNDG
TH_0916|M.thermoresistible__bu GNLRLTDTDGGELD------GDSELDRAMGPMQFIPETWRLYGVDANNDG
MAB_1164|M.abscessus_ATCC_1997 GNLRLPDTDKGVLD------GDANQDRAMGPMQFIPETWRIYGVRAAGDG
*.: : * : .: *********.*** :.* * .**
Mb1050|M.bovis_AF2122/97 IANVDNIDDAALSAAGYLCWRGKDLATPRGWITALRAYNNSVIYARAVRD
Rv1022|M.tuberculosis_H37Rv IANVDNIDDAALSAAGYLCWRGKDLATPRGWITALRAYNNSVIYARAVRD
MMAR_4463|M.marinum_M IVSPDNIDDAALSAAGYLCWRGKDLATARGWITALRAYNNSGVYARAVRD
MUL_4632|M.ulcerans_Agy99 IVSPDNIDDAALSAAGYLCWRGKDLATARGWITALRAYNNSGVYARAVRD
MAV_1163|M.avium_104 RVSPDNIDDAALAAAGYLCWRGKDLATPRGWITALRAYNNSGVYARAVRD
Mvan_4772|M.vanbaalenii_PYR-1 DVSADNIDDAALSAAGYLCWRGKDLSKPRGWMEALRAYNHSDQYARTVRD
Mflv_1953|M.gilvum_PYR-GCK DVSVDNIDDAALSAAGYLCWRGKDLSKPRGWMEALRAYNYSDAYARNVRD
MSMEG_5416|M.smegmatis_MC2_155 KVDPDNFDDAALSAAGVLCWYGKDLSDPRGWMRALRAYNYSDQYARAVRD
TH_0916|M.thermoresistible__bu VVDPDNIDDAALSAAGYLCWRGKDLSTPRGWMEALRAYNYSDPYARSVRD
MAB_1164|M.abscessus_ATCC_1997 EPSPDNIDDAALSAAGYLCSRGGDLSTTDGWIKALWAYNMSDVYAEQVRD
. **:*****:*** ** * **: . **: ** *** * **. ***
Mb1050|M.bovis_AF2122/97 WATAYAAGHPL
Rv1022|M.tuberculosis_H37Rv WATAYAAGHPL
MMAR_4463|M.marinum_M WATAYAAGHPL
MUL_4632|M.ulcerans_Agy99 WATAYAAGHPL
MAV_1163|M.avium_104 WATAYAKGHPL
Mvan_4772|M.vanbaalenii_PYR-1 WATAYAQGHPL
Mflv_1953|M.gilvum_PYR-GCK YATAYAQGHPL
MSMEG_5416|M.smegmatis_MC2_155 WATAYAAGHAL
TH_0916|M.thermoresistible__bu WATAYANGHGL
MAB_1164|M.abscessus_ATCC_1997 WATAYAKGATL
:***** * *