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MLTVVHDAAEANESAGGAGRSLLDEIVRDGARQMLAAALQAEVAAYVAQFADQLDEDGHRLVVRNGYHQA REVLTAAGAVEVTAPRVNDRRVDPDTGVRQRFSSAILPAWARKSPQISEVLPLLYLHGLSSGDFGPALEQ FLGSGAGLSASTITRLTAQWQDEAATFGRRDLSGTDYVYLWVDGIHLKVRLEQTKLCLLVMIGVRADGRK ELVAITDGYRESTESWADLLRDCKRRGMTAPVLAVGDGALGFWRAVREVFPATREQRCWFHKQANVLAAL PKSAHPSALAALKDIYNAEDTDKAQLAVKAFEVDFGAKYPKAVAKIVDDLDVLLEFYKYPAEHWIHLRTT NPIESTFATVRLRTKVTKGPGSRTAGIAMAYKLIDAAQARWRAVNAPHLVALVRAGAVFHKGKLLERPTD ITPPTPPSNGDESTGTEVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4741 | - | - | 100% (439) | transposase, mutator type |
| M. vanbaalenii PYR-1 | Mvan_2066 | - | 0.0 | 100.00% (439) | transposase, mutator type |
| M. vanbaalenii PYR-1 | Mvan_0604 | - | 0.0 | 100.00% (439) | transposase, mutator type |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3664c | - | 4e-29 | 24.54% (379) | putative transposase |
| M. gilvum PYR-GCK | Mflv_3191 | - | 3e-31 | 27.69% (372) | transposase, mutator type |
| M. tuberculosis H37Rv | Rv3640c | - | 3e-29 | 24.54% (379) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_2671 | - | 0.0 | 84.74% (439) | transposase, Mutator family protein |
| M. smegmatis MC2 155 | MSMEG_4159 | - | 0.0 | 90.43% (439) | IS6120, transposase |
| M. thermoresistible (build 8) | TH_1996 | - | 0.0 | 90.23% (440) | IS6120, transposase |
| M. ulcerans Agy99 | MUL_2955 | - | 3e-23 | 25.41% (362) | fusion protein of transposase for IS2606 and sialic |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3664c|M.bovis_AF2122/97 --------------------------------MALPQSALSELLDAFRTG
Rv3640c|M.tuberculosis_H37Rv --------------------------------MALPQSALSELLDAFRTG
Mflv_3191|M.gilvum_PYR-GCK --------------------------------MTQDHSALLAQLDALRSA
MSMEG_4159|M.smegmatis_MC2_155 --------------------------------MLTVVHDTEDAND-KASG
TH_1996|M.thermoresistible__bu --------------------------------MLTVVHDGAEANDNTDSG
Mvan_4741|M.vanbaalenii_PYR-1 --------------------------------MLTVVHDAAEANE-SAGG
MAV_2671|M.avium_104 --------------------------------MLTVVHDQDSSNE-DACG
MUL_2955|M.ulcerans_Agy99 MMTKTVVAVQPSQNHEDEAGAVAAIDVPSSRDVDELEVARELVRQAREAG
: : .
Mb3664c|M.bovis_AF2122/97 DGVDLIRDAVRLVLQELSELEATERIG------AARYERSDTRVTDRNG-
Rv3640c|M.tuberculosis_H37Rv DGVDLIRDAVRLVLQELSELEATERIG------AARYERSDTRVTDRNG-
Mflv_3191|M.gilvum_PYR-GCK DAGAVFAELIRAGLQQLIEAEATAAIG------AGRYQRTDGRMVHRNG-
MSMEG_4159|M.smegmatis_MC2_155 AGRSLLDEIVRDGARQMLAAALQAEVAAYVAQFADQLDENGHRLVVRNGY
TH_1996|M.thermoresistible__bu AGRSLLDEIVRDGARQMLAAALQAEVAAYVAQFADQLDENGHRLVVRNGY
Mvan_4741|M.vanbaalenii_PYR-1 AGRSLLDEIVRDGARQMLAAALQAEVAAYVAQFADQLDEDGHRLVVRNGY
MAV_2671|M.avium_104 S-RSLLDEIVRDGARQMLAAALAAEVAAYIDAHAGEVDENGHRLVVRNGY
MUL_2955|M.ulcerans_Agy99 VGLTGPGGLLKAMTKTVIETALDEELSEHLG--HDRHDRAGYGSGNSRNR
:: : : :. . :. . ..
Mb3664c|M.bovis_AF2122/97 ARSRVLSTQAG-DVELRIPKLR----------KGSFFPAILEPRRRIDQA
Rv3640c|M.tuberculosis_H37Rv ARSRVLSTQAG-DVELRIPKLR----------KGSFFPAILEPRRRIDQA
Mflv_3191|M.gilvum_PYR-GCK HRPKTVSTTSG-DIEVQIPKLR----------AGSFFPSLLERRRRIDKA
MSMEG_4159|M.smegmatis_MC2_155 HQPREVLTAAG-AVQVKAPRVNDRRVDPDTGERKRFSSAILPAWARKSPQ
TH_1996|M.thermoresistible__bu HQPREVLTAAG-AVQVRAPRVNDKRVDPDTGERKRFSSAILPAWARKSPQ
Mvan_4741|M.vanbaalenii_PYR-1 HQAREVLTAAG-AVEVTAPRVNDRRVDPDTGVRQRFSSAILPAWARKSPQ
MAV_2671|M.avium_104 HREREVLTAAG-AVTVIAPRVNDKRIDADTAERRRFSSAILPAWARKSPQ
MUL_2955|M.ulcerans_Agy99 TRSKTVLTDACGSIEIDVPRDR----------AGTFEPKTVEKRQRRLTD
: : : * : : : *: . * . : *
Mb3664c|M.bovis_AF2122/97 LYAVVMEAYVHGISTRAVD-DLVEAMGVETGISKSEVSRICAGLDEIVGA
Rv3640c|M.tuberculosis_H37Rv LYAVVMEAYVHGISTRAVD-DLVEAMGVETGISKSEVSRICAGLDEIVGA
Mflv_3191|M.gilvum_PYR-GCK LHAVIMEAYVHGVSTRSVD-DLVAAMGVESGVSKSEVSRICAGLDIEIEA
MSMEG_4159|M.smegmatis_MC2_155 MSEVLPLLYLHGLSSNDFTPALEQFLGSGAGLSASTITRLTAQWQDEARA
TH_1996|M.thermoresistible__bu MSEVLPLLYLHGLSSNDFTPALEQFLGSGAGLSASTITRLTSQWQDEAAA
Mvan_4741|M.vanbaalenii_PYR-1 ISEVLPLLYLHGLSSGDFGPALEQFLGSGAGLSASTITRLTAQWQDEAAT
MAV_2671|M.avium_104 MTEVLPLLYLHGLSTSDFGPALEQFLGSGAGLSATTITRLTAQWQDEAKA
MUL_2955|M.ulcerans_Agy99 VDEVVLSLYARGLTTGEISAHFAHIY--DAAVSKDTVSRITDRVLEEMTA
: *: * :*::: . : :.:* ::*: :
Mb3664c|M.bovis_AF2122/97 FRTRTLGHIEFPYVYLDATYLNVRNGTGQVVSMAVIVASGIAADGSREIL
Rv3640c|M.tuberculosis_H37Rv FRTRTLGHIEFPYVYLDATYLNVRNGTGQVVSMAVIVASGIAADGSREIL
Mflv_3191|M.gilvum_PYR-GCK FRTRSLAHTEFPYIFCDATFCKVRVG-AHVVSQALVVATGVSIDGTREVL
MSMEG_4159|M.smegmatis_MC2_155 FGARDLSATDYVYLWVDGIHLKVRLD---QEKLCLLVMLGVRADGRKELV
TH_1996|M.thermoresistible__bu FGRRDLSATDYVYLWVDGIHLKVRLD---QEKLCLLVMLGMRADGRKELV
Mvan_4741|M.vanbaalenii_PYR-1 FGRRDLSGTDYVYLWVDGIHLKVRLE---QTKLCLLVMIGVRADGRKELV
MAV_2671|M.avium_104 FGERDLSGTDYVYLWVDGIHLKVRLE---QEKLCLLVMIGVRSDGRKELV
MUL_2955|M.ulcerans_Agy99 WHTRPLER-VYAAVFIDALHVKIRDG--QVGPRPVYAAVGVDLAGHRDVL
: * * : :: *. . ::* : . *: * ::::
Mb3664c|M.bovis_AF2122/97 GLDVG--DSEDETFWRGFLTSLKGRGLGGVRLVISDQHAGLVKALKRCFQ
Rv3640c|M.tuberculosis_H37Rv GLDVG--DSEDETFWRGFLTSLKGRGLGGVRLVISDQHAGLVKALKRCFQ
Mflv_3191|M.gilvum_PYR-GCK GTAVG--DSESFEFWREFLASLKARGLTGVHLVISDAHVGLKTAVAQQFT
MSMEG_4159|M.smegmatis_MC2_155 AITDG--YRESAESWADLLRDCKRRGMTAPVLAIGDGALGFWKAVREVFP
TH_1996|M.thermoresistible__bu AITDG--YRESAESWADLLRDCKRRGMTAPVLAIGDGALGFWKAVREVFP
Mvan_4741|M.vanbaalenii_PYR-1 AITDG--YRESTESWADLLRDCKRRGMTAPVLAVGDGALGFWRAVREVFP
MAV_2671|M.avium_104 GLADG--YRESTESWADLLRSCRRRGMTAPVLAVGDGALGFWKAMREVFP
MUL_2955|M.ulcerans_Agy99 GMWAGEGDGESAKYWLAVLTELKNRGVADIFFLVCDGLKGLPDSVSAVFP
. * *. * .* . : **: : : * *: :: *
Mb3664c|M.bovis_AF2122/97 GAGHQRCRVHFARNLLAHVPKDKADMVASMFRMIFSAPDAEAVHATWEEV
Rv3640c|M.tuberculosis_H37Rv GAGHQRCRVHFARNLLAHVPKDKADMVASMFRMIFSAPDAEAVHATWEGV
Mflv_3191|M.gilvum_PYR-GCK NSSWQRCRVHFMRNLHTAVAAKHAPAVTAAVKTIFAHTDPVEVAAQWDRV
MSMEG_4159|M.smegmatis_MC2_155 ATKEQRCWFHKQANVLAALPKSAHPSALAAIKEIYNAEDIDKAQIAVKAF
TH_1996|M.thermoresistible__bu ATKEQRCWFHKQANVLAALPTSAHQSALAAIKEIYNAEDIDKAQIAVKAF
Mvan_4741|M.vanbaalenii_PYR-1 ATREQRCWFHKQANVLAALPKSAHPSALAALKDIYNAEDTDKAQLAVKAF
MAV_2671|M.avium_104 ATREQRCWFHKQANVLSCLPKSAHPGALAAMREIYNAEDIDHAQVAIKAF
MUL_2955|M.ulcerans_Agy99 DTVVQTCIIHLIRGTFRYAGRQHHTAIARALKPIYTAVNAAAAAEALDAF
: * * .* . . .: *: : . . .
Mb3664c|M.bovis_AF2122/97 RDRLAASFPKIGPLMDDARAEVLAFTAFPKAHWQKIWSTNPLERINKEIK
Rv3640c|M.tuberculosis_H37Rv RDRLAASFPKIGPLMDDARAEVLAFTAFPKAHWQKIWSTNPLERINKEIK
Mflv_3191|M.gilvum_PYR-GCK ADTLAPSFPKVAAMMGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIK
MSMEG_4159|M.smegmatis_MC2_155 EADFGAKYPKAVAKITDDLDVLLEFYKYPAEHWIHLRTTNPIESTFATVR
TH_1996|M.thermoresistible__bu EADFGAKYPKAVAKITDDLDVLLEFYKYPAEHWIHLRTTNPIESTFATVR
Mvan_4741|M.vanbaalenii_PYR-1 EVDFGAKYPKAVAKIVDDLDVLLEFYKYPAEHWIHLRTTNPIESTFATVR
MAV_2671|M.avium_104 EVDYGAKYPKAVAKIVDDADVLLEFYRYPAEHWIHLRTTNPIESTFATVR
MUL_2955|M.ulcerans_Agy99 DTGWGHRYPAAIRLWRNAWNEFIPFLDYDTEIRKVICSTNAIESLNARYR
. :* : .: * : : :.*.:* :
Mb3664c|M.bovis_AF2122/97 RRSRVVGIFPNPAAVIRLVGAVLADMHDE----------WQASERRYLSE
Rv3640c|M.tuberculosis_H37Rv RRSRVVGIFPNPAAVIRLVGAVLADMHDE----------WQASERRYLSE
Mflv_3191|M.gilvum_PYR-GCK RRADVVEIFPNPAAFLRLATAVVIEAHDE----------WQVT-RRYLSD
MSMEG_4159|M.smegmatis_MC2_155 LRTKVTKGPGSRAAGLAMAYKLIDAAAAR----------WRAVNAPHLVA
TH_1996|M.thermoresistible__bu LRTKVTKGPGSRAAGLAMAYKLIDAAAAR----------WRAVNAPHLVA
Mvan_4741|M.vanbaalenii_PYR-1 LRTKVTKGPGSRTAGIAMAYKLIDAAQAR----------WRAVNAPHLVA
MAV_2671|M.avium_104 LRTKVTKGPGSRAAGIAMAYKLIDAAQAR----------WRAVNAPHLVA
MUL_2955|M.ulcerans_Agy99 RAIRARGHFPTEQSALKCLYLVTRSLDPTGTGQKRWTMRWKPALNVDQRN
. . : : : *:
Mb3664c|M.bovis_AF2122/97 ASMALLYPDSDNAVVAAISGGQ----------------------------
Rv3640c|M.tuberculosis_H37Rv ASMALLYPDSDNAVVAAISGGQ----------------------------
Mflv_3191|M.gilvum_PYR-GCK ISMDELRVVIEKKHAAAALAKQHQIT------------------------
MSMEG_4159|M.smegmatis_MC2_155 LVRAGAVFHKGRLLERPTDITPPTSPSDGGQHAGTEVA------------
TH_1996|M.thermoresistible__bu LVRAGAVFHKGKLLERPTEITPPTPPSDGDQQAGTEVA------------
Mvan_4741|M.vanbaalenii_PYR-1 LVRAGAVFHKGKLLERPTDITPPTPPSNGDESTGTEVA------------
MAV_2671|M.avium_104 LVRAGAVFHKGKLLERPVDITPPEP----AESAETEVA------------
MUL_2955|M.ulcerans_Agy99 SFIAAFLGWTMDAFDYFIVVLVYADIAKTFHHTKTEVAFVTTATLAMRPV
Mb3664c|M.bovis_AF2122/97 --------------------------------------------------
Rv3640c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3191|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4159|M.smegmatis_MC2_155 --------------------------------------------------
TH_1996|M.thermoresistible__bu --------------------------------------------------
Mvan_4741|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2671|M.avium_104 --------------------------------------------------
MUL_2955|M.ulcerans_Agy99 GALIFGLWADRVGRRVPLMVDVALYSVVGFLCAFAPNFTVLVILRLLYDI
Mb3664c|M.bovis_AF2122/97 --------------------------------------------------
Rv3640c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3191|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4159|M.smegmatis_MC2_155 --------------------------------------------------
TH_1996|M.thermoresistible__bu --------------------------------------------------
Mvan_4741|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2671|M.avium_104 --------------------------------------------------
MUL_2955|M.ulcerans_Agy99 GMGGEWGLGAALAMEKVPVGRRGFFSGLLQEGYAFGYLLATVSSLVVMNW
Mb3664c|M.bovis_AF2122/97 --------------------------------------------------
Rv3640c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3191|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4159|M.smegmatis_MC2_155 --------------------------------------------------
TH_1996|M.thermoresistible__bu --------------------------------------------------
Mvan_4741|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2671|M.avium_104 --------------------------------------------------
MUL_2955|M.ulcerans_Agy99 LGLSWRWLFGLSIIPALISLIIRYRVKESEVWEAAQDRMRLTKTRVRDVL
Mb3664c|M.bovis_AF2122/97 --------------------------------------------------
Rv3640c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3191|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4159|M.smegmatis_MC2_155 --------------------------------------------------
TH_1996|M.thermoresistible__bu --------------------------------------------------
Mvan_4741|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2671|M.avium_104 --------------------------------------------------
MUL_2955|M.ulcerans_Agy99 RNAAIIRRFVYLVLLMTAFNWMSHGTQDVYPSFLTATTDHGAGLSSATAR
Mb3664c|M.bovis_AF2122/97 --------------------------------------------------
Rv3640c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3191|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4159|M.smegmatis_MC2_155 --------------------------------------------------
TH_1996|M.thermoresistible__bu --------------------------------------------------
Mvan_4741|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2671|M.avium_104 --------------------------------------------------
MUL_2955|M.ulcerans_Agy99 WIVVVYNAGAIIGGLMFGTLSQRFGRRYTIAFCAVLALPVVPIFAYSRTA
Mb3664c|M.bovis_AF2122/97 --------------------------------------------------
Rv3640c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3191|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4159|M.smegmatis_MC2_155 --------------------------------------------------
TH_1996|M.thermoresistible__bu --------------------------------------------------
Mvan_4741|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2671|M.avium_104 --------------------------------------------------
MUL_2955|M.ulcerans_Agy99 AMLCLGSFLMQLCVQGAWGVIPAYLTEMSPDAIRGLYPGVTYQLGNLLAA
Mb3664c|M.bovis_AF2122/97 --------------------------------------------------
Rv3640c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3191|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4159|M.smegmatis_MC2_155 --------------------------------------------------
TH_1996|M.thermoresistible__bu --------------------------------------------------
Mvan_4741|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2671|M.avium_104 --------------------------------------------------
MUL_2955|M.ulcerans_Agy99 MNLPIQEHLAETHGYPFALAVTIVPVLTVVAVLALIGKDATGVHFGTAET
Mb3664c|M.bovis_AF2122/97 --------------------------------------------------
Rv3640c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3191|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4159|M.smegmatis_MC2_155 --------------------------------------------------
TH_1996|M.thermoresistible__bu --------------------------------------------------
Mvan_4741|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2671|M.avium_104 --------------------------------------------------
MUL_2955|M.ulcerans_Agy99 AFLPGKTWRRQRRDREMRAPASPTRGRSPHDRPAANRRPSYSLNARRNRC
Mb3664c|M.bovis_AF2122/97 --------------------------------------------------
Rv3640c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3191|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4159|M.smegmatis_MC2_155 --------------------------------------------------
TH_1996|M.thermoresistible__bu --------------------------------------------------
Mvan_4741|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2671|M.avium_104 --------------------------------------------------
MUL_2955|M.ulcerans_Agy99 MATVVERSRMSDRFPGSRSVRVTLRPSPTNTQKQTVPTGFCSVPPPGPAI
Mb3664c|M.bovis_AF2122/97 ------------------------------------------------
Rv3640c|M.tuberculosis_H37Rv ------------------------------------------------
Mflv_3191|M.gilvum_PYR-GCK ------------------------------------------------
MSMEG_4159|M.smegmatis_MC2_155 ------------------------------------------------
TH_1996|M.thermoresistible__bu ------------------------------------------------
Mvan_4741|M.vanbaalenii_PYR-1 ------------------------------------------------
MAV_2671|M.avium_104 ------------------------------------------------
MUL_2955|M.ulcerans_Agy99 PVIATAVSAPKRWNAPAAMACATGSETAPCISISAGSTPSNSALASLE