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STEKFVWGRRNSRSLEERYVTQSQSRQPDLRTYVLDTSVLLSDPWAITRFAEHEVVVPLVVISELEAKRH HHELGWFARQALRMFDDLRLEHGRLDQPIPVGAQGGTLHVELNHSDPTVLPAGFRTDSNDARILTVAANL AAEGKHVTLVSKDIPLRVKAGAVGLLADEYHAQDVVTSGWTGMAELEVPGADVDALFADGEIDLEAARDL PCHTGIRMLGSNSHALGRVNADKRVQLVRGDREVFGLRGRSAEQRVALDLLLDESVGIVSLGGKAGTGKS ALALCAGLEAVLERRTQRKVVVFRPLYAVGGQDLGYLPGSESEKMGPWAQAVFDTLEGLASPAVLEEVLS RGMLEVLPLTHIRGRSLHDSFVIVDEAQSLERNVLLTVLSRLGAGSRVVLTHDVAQRDNLRVGRHDGVAA VIEKLKGHPLFAHITLLRSERSPIAALVTEMLEEISPGALP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4652 | - | - | 100% (462) | PhoH family protein |
| M. vanbaalenii PYR-1 | Mvan_3832 | - | 2e-24 | 34.25% (181) | PhoH family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1125 | phoH2 | 0.0 | 92.29% (428) | PhoH-like protein PhoH2 (phosphate starvation-inducible |
| M. gilvum PYR-GCK | Mflv_2062 | - | 0.0 | 93.79% (451) | PhoH family protein |
| M. tuberculosis H37Rv | Rv1095 | phoH2 | 0.0 | 92.29% (428) | PhoH-like protein PhoH2 (phosphate starvation-inducible |
| M. leprae Br4923 | MLBr_01951 | phoH2 | 0.0 | 89.95% (428) | PhoH-like protein |
| M. abscessus ATCC 19977 | MAB_1239 | - | 0.0 | 88.11% (429) | PhoH-like protein PhoH2 (phosphate starvation-inducible protein |
| M. marinum M | MMAR_4372 | phoH2 | 0.0 | 90.42% (428) | PhoH-like protein PhoH2 |
| M. avium 104 | MAV_1217 | - | 0.0 | 90.89% (428) | PhoH2 protein |
| M. smegmatis MC2 155 | MSMEG_5247 | - | 0.0 | 93.98% (432) | PhoH family protein |
| M. thermoresistible (build 8) | TH_2158 | - | 0.0 | 88.89% (450) | PhoH family protein |
| M. ulcerans Agy99 | MUL_3621 | phoH1 | 9e-26 | 38.56% (153) | PhoH-like protein PhoH1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4652|M.vanbaalenii_PYR-1 ----MSTEKFVWGRRNSRSLEERYVTQSQSRQPDLRTYVLDTSVLLSDPW
Mflv_2062|M.gilvum_PYR-GCK --------------MNTRSLEERYVTDSITR-----TYVLDTSVLLSDPW
MSMEG_5247|M.smegmatis_MC2_155 ------------------------MTEQAVR-----TYVLDTSVLLSDPW
TH_2158|M.thermoresistible__bu ------VSSIKSYVREPHVLEERFVTDSPVR-----TYVLDTSVLLSDPW
Mb1125|M.bovis_AF2122/97 ------------------------MTD--TR-----TYVLDTSVLLSDPW
Rv1095|M.tuberculosis_H37Rv ------------------------MTD--TR-----TYVLDTSVLLSDPW
MAV_1217|M.avium_104 ------------------------MTD--IR-----TYVIDTSVLLSDPW
MLBr_01951|M.leprae_Br4923 ------------------------MTD--IR-----TYVIDTSVLLSDPW
MMAR_4372|M.marinum_M ------------------------MTD--IR-----TYVLDTSVLLSDPW
MAB_1239|M.abscessus_ATCC_1997 MPHGCQERSVTASKNPGTKADDLRASGSSIR-----TYVLDTSVLLSDPW
MUL_3621|M.ulcerans_Agy99 --------------------------------------------------
Mvan_4652|M.vanbaalenii_PYR-1 AITRFAEHEVVVPLVVISELEAKRHHHELGWFARQALRMFDDLRLEHGRL
Mflv_2062|M.gilvum_PYR-GCK AITRFAEHEVVVPLVVISELEAKRHHHELGWFARQSLRLFDDLRLEHGRL
MSMEG_5247|M.smegmatis_MC2_155 ACTRFAEHEVVVPLVVISELEAKRHHHELGWFARQALRMFDDMRLEHGRL
TH_2158|M.thermoresistible__bu AFLRFAEHEVVVPLVVISELEAKRHHHELGWFARQALRMFDDLRLEHGRL
Mb1125|M.bovis_AF2122/97 ACSRFAEHDVVVPLVVISELEAKRHHHELGWFARQALRLFDDLRLEHGRL
Rv1095|M.tuberculosis_H37Rv ACSRFAEHDVVVPLVVISELEAKRHHHELGWFARQALRLFDDLRLEHGRL
MAV_1217|M.avium_104 ACSRFAEHEVVVPLVVISELEAKRHHHELGWFARQALRLFDDLRLLHGRL
MLBr_01951|M.leprae_Br4923 ACSRFAEHEVVVPLVVISELEAKRHHHELGWFARQALRLFDDLRLDHGRL
MMAR_4372|M.marinum_M ACSRFAEHEVVVPLVVISELEAKRHHHELGWFARQALRLFDDLRLEHGRL
MAB_1239|M.abscessus_ATCC_1997 ATNRFAEHEVVIPLVVISELEGKRHHHELGWFARTALRMLDDLRLEYGRL
MUL_3621|M.ulcerans_Agy99 --------------------------------------------MTPRET
: .
Mvan_4652|M.vanbaalenii_PYR-1 DQPIPVGAQGGTLHVELNHSDPTVLPAGFRTDSNDARILTVAANLAAEGK
Mflv_2062|M.gilvum_PYR-GCK DEPIPVGTEGGTLHVELNHSDPSVLPAGFRNDSNDARILTVAANLAAEGK
MSMEG_5247|M.smegmatis_MC2_155 DQPVPVGTQGGTLHVELNHSDPSVLPAGFRNDSNDARILTVAANLAAEGK
TH_2158|M.thermoresistible__bu DRPVPVGTQGGSLHVELNHSDPSVLPPGFRGDSNDSRILTCAANLAAEGR
Mb1125|M.bovis_AF2122/97 DQPIPVGTQGGTLHVELNHTDPAVLPAGFRTDSNDSRILSCAANLAAEGK
Rv1095|M.tuberculosis_H37Rv DQPIPVGTQGGTLHVELNHTDPAVLPAGFRTDSNDSRILSCAANLAAEGK
MAV_1217|M.avium_104 DQPIPVGTQGGSLHVELNHTDPAVLPAGFRSDSNDSRILSCAANLAAEGK
MLBr_01951|M.leprae_Br4923 DQPIPVGMQGGTLHVELNHSDPTVLPAGFRTDSNDSRILSCAANLAAEGR
MMAR_4372|M.marinum_M DQPIPVGKQGGSLHVELNHTDPSVLPAGFRTDSNDSRILSCAANLAAEGR
MAB_1239|M.abscessus_ATCC_1997 DQSIPVGTQGGSLRVELNHTDPSVLPVGFRTDSNDSRILACALNLAAEGK
MUL_3621|M.ulcerans_Agy99 RAADAVGARPADPQVRSSIDVPPDLVVGLLG-SADENLRALERTLTAS--
. .** . . :*. . *. * *: * * .: : .*:*.
Mvan_4652|M.vanbaalenii_PYR-1 HVTLVSKDIPLRVKAGAVGLLADEYHAQDVVTSGWTGMAELEVPGADVDA
Mflv_2062|M.gilvum_PYR-GCK QVTLVSKDIPLRVKAGAVGLLADEYRAQDVVTSGWTGMAEVEVPSEDIDT
MSMEG_5247|M.smegmatis_MC2_155 HVTLVSKDIPLRVKAGAVGLAADEYHAQDVVVSGWTGMTEMDVAGEDIDT
TH_2158|M.thermoresistible__bu RVTLVSKDIPLRVKAAAVGLSADEYHAQDVVTSGWTGMTELDVAPDDIAT
Mb1125|M.bovis_AF2122/97 RVTLVSKDIPLRVKAAAVGLAADEYHAQDVVVSGWSGMHELETASADIDA
Rv1095|M.tuberculosis_H37Rv RVTLVSKDIPLRVKAAAVGLAADEYHAQDVVVSGWSGMHELETASADIDA
MAV_1217|M.avium_104 RVTLVSKDIPLRVKAAAVGLAADEYHAQDVVASGWSGMHELETATEDIDA
MLBr_01951|M.leprae_Br4923 RVTLVSKDLPLRVKAAAVGLAADEYHAQDVVASGWSGMHEIETCAEDIDA
MMAR_4372|M.marinum_M RVTLVSKDIPLRVKAAAVGLAADEYHAQDVVASGWSGMHEIETAAGDIDA
MAB_1239|M.abscessus_ATCC_1997 LVTLVSKDIPLRVKAGAVGLAADEYRAQDVVNSGWTGMTELDTSADVIDS
MUL_3621|M.ulcerans_Agy99 ----------LHVRGNTVTLAGEP-----------ADVAIAERAVSELVA
*:*:. :* * .: :.: : : :
Mvan_4652|M.vanbaalenii_PYR-1 LFADGEIDLEAARDLPCHTGIRMLGSNSHALGRVNADKRVQLVRGDREVF
Mflv_2062|M.gilvum_PYR-GCK LFADGEVDLEGARDLPCHTGVRLLGSTSHALGRVNADKRVQLVRGDREVF
MSMEG_5247|M.smegmatis_MC2_155 LFADGEIDLAEARDLPCHTGIRLLGGTSHALGRVNAAKKVQLVRGDREVF
TH_2158|M.thermoresistible__bu LFADGELDLAEARGLPCHTGIRLLGGTSHALGRVNPDKRVQLVRGDREVF
Mb1125|M.bovis_AF2122/97 LFADGEIDLVEARDLPCHTGIRLLGGGSHALGRVNAHKRVQLVRGDREAF
Rv1095|M.tuberculosis_H37Rv LFADGEIDLVEARDLPCHTGIRLLGGGSHALGRVNAHKRVQLVRGDREAF
MAV_1217|M.avium_104 LFTEGEIDLAEARDLPCHTGIRLLGGSSHALGRVNPDKRVQLVRGDREAF
MLBr_01951|M.leprae_Br4923 LFAEGKIDLGEARDLPCHTGIRLLGSNSHALGRVTAAKRVQLVRGDREVF
MMAR_4372|M.marinum_M LFADGEIDLAEARDLPCHTGVRLLGGSSHALGRVTAAKRVQLVRGDREVF
MAB_1239|M.abscessus_ATCC_1997 LFESGEVDLEAARDLPCHTGVRLLGGTSSALGRVNAEKRVQLVRGDREVF
MUL_3621|M.ulcerans_Agy99 IVANG---QPLTPEVVRHSVAMLVG-----AGNESPAEVLTLDILSRRGK
:. .* : : *: ::* *. .. : : * .*.
Mvan_4652|M.vanbaalenii_PYR-1 GLRGRSAEQRVALDLLLDESVGIVSLGGKAGTGKSALALCAGLEAVLERR
Mflv_2062|M.gilvum_PYR-GCK GLRGRSAEQRVALDLLLDESVGIVSLGGKAGTGKSALALCAGLEAVLERR
MSMEG_5247|M.smegmatis_MC2_155 GLRGRSAEQRVALDLLLDESVGIVSLGGKAGTGKSALALCAGLEAVLERR
TH_2158|M.thermoresistible__bu GLRGRSAEQRVALDLLLDESVGIVSLGGKAGTGKSALALCAGLEAVLERR
Mb1125|M.bovis_AF2122/97 GLRGRSAEQRVALDLLLDESVGIVSLGGKAGTGKSALALCAGLEAVLERR
Rv1095|M.tuberculosis_H37Rv GLRGRSAEQRVALDLLLDESVGIVSLGGKAGTGKSALALCAGLEAVLERR
MAV_1217|M.avium_104 GLRGRSAEQRVALDLLLDESVGIVSLGGKAGTGKSALALCAGLEAVLERR
MLBr_01951|M.leprae_Br4923 GLRGRSAEQRVALDLLLDESVGIVSLGGKAGTGKSALALCAGLEAVLERR
MMAR_4372|M.marinum_M GLRGRSAEQRVALDLLLDESVGIVSMGGKAGTGKSALALCAGLEAVLERR
MAB_1239|M.abscessus_ATCC_1997 GLRGRSAEQRVALDILLDESVGIVSLGGKAGTGKSALALCAGLEAVLERR
MUL_3621|M.ulcerans_Agy99 TIRPKTLNQKRYVDAIDAN--TIVFGIGPAGTGKTYLAMAKAVHALQTKQ
:* :: :*: :* : : ** * *****: **:. .:.*: ::
Mvan_4652|M.vanbaalenii_PYR-1 TQRKVVVFRPLYAVGGQDLGYLPGSESEKMGPWAQAVFDTLEGLASPAVL
Mflv_2062|M.gilvum_PYR-GCK TQRKVVVFRPLYAVGGQDLGYLPGSESEKMGPWAQAVFDTLEGLASPAVL
MSMEG_5247|M.smegmatis_MC2_155 TQRKVVVFRPLYAVGGQDLGYLPGSESEKMGPWAQAVFDTLEGLASPAVL
TH_2158|M.thermoresistible__bu THRKVVVFRPLYAVGGQELGYLPGTEAEKMGPWAQAVFDTLEGLASPAVL
Mb1125|M.bovis_AF2122/97 THRKVVVFRPLYAVGGQELGYLPGSESEKMGPWAQAVFDTLEGLASPAVL
Rv1095|M.tuberculosis_H37Rv THRKVVVFRPLYAVGGQELGYLPGSESEKMGPWAQAVFDTLEGLASPAVL
MAV_1217|M.avium_104 TQRKVVVFRPLYAVGGQELGYLPGSESEKMGPWAQAVFDTLEGLASPAVL
MLBr_01951|M.leprae_Br4923 SHRKVVVFRPLYAVGGQELGYLPGSESEKMGPWAQAVFDTLEGLASPAVL
MMAR_4372|M.marinum_M THRKVVVFRPLYAVGGQELGYLPGSESDKMGPWAQAVFDTLEGLASPAVL
MAB_1239|M.abscessus_ATCC_1997 SHRKVVVFRPLYAVGGQELGYLPGSESEKMGPWAQAVFDTLEGLASPAVI
MUL_3621|M.ulcerans_Agy99 VN-RIILTRPAVEAG-ERLGFLPGTLSEKIDPYLRPLYDALYDMMDPELI
: :::: ** .* : **:***: ::*:.*: :.::*:* .: .* ::
Mvan_4652|M.vanbaalenii_PYR-1 EEVLSRGMLEVLPLTHIRGRSLHDSFVIVDEAQSLERNVLLTVLSRLGAG
Mflv_2062|M.gilvum_PYR-GCK EEVLSRGMLEVLPLTHIRGRSLHDSFVIVDEAQSLERNVLLTVLSRLGAG
MSMEG_5247|M.smegmatis_MC2_155 DEVLSRGMLEVLPLTHIRGRSLHDSFVIVDEAQSLERNVLLTVLSRLGAG
TH_2158|M.thermoresistible__bu EEVLSRGMLEVLPLTHIRGRSLHDSFVIVDEAQSLERNVLLTVLSRLGAG
Mb1125|M.bovis_AF2122/97 EEVLSRGMLEVLPLTHIRGRSLHDSFVIVDEAQSLERNVLLTVLSRLGTG
Rv1095|M.tuberculosis_H37Rv EEVLSRGMLEVLPLTHIRGRSLHDSFVIVDEAQSLERNVLLTVLSRLGTG
MAV_1217|M.avium_104 DEVLSRGMLEVLPLTHIRGRSLHDSFVIVDEAQSLERNVLLTVLSRLGTG
MLBr_01951|M.leprae_Br4923 EEVLSRSMLEVLPLTHIRGRSLHDSFVIVDEAQSLERNVLLTVLSRLGTG
MMAR_4372|M.marinum_M EEVLSRGMLEVLPLTHIRGRSLHDSFVIVDEAQSLERNVLLTVLSRLGTG
MAB_1239|M.abscessus_ATCC_1997 EEVLSRGMLEVLPLTHIRGRSLHDSFVIVDEAQSLERNVLLTVLSRLGTG
MUL_3621|M.ulcerans_Agy99 AKLMSAGVIEVAPLAYMRGRTLNDAFIVLDEAQNTTAEQMKMFLTRLGFG
:::* .::** **:::***:*:*:*:::****. : : .*:*** *
Mvan_4652|M.vanbaalenii_PYR-1 SRVVLTHDVAQRDNLRVGRHDGVAAVIEKLKGHPLFAHITLLRSERSPIA
Mflv_2062|M.gilvum_PYR-GCK SRVVLTHDVAQRDNLRVGRHDGVAAVIEKLKGHPLFAHITLLRSERSPIA
MSMEG_5247|M.smegmatis_MC2_155 SRVVLTHDVAQRDNLRVGRHDGVAAVIEKLKGHPLFAHVTLQRSERSPIA
TH_2158|M.thermoresistible__bu SRVVLTHDVAQRDNLRVGRHDGVAAVIEKLKGHPLFAHITLSRSERSPIA
Mb1125|M.bovis_AF2122/97 SRVVLTHDIAQRDNLRVGRHDGVAAVIEKLKGHPLFAHITLLRSERSPIA
Rv1095|M.tuberculosis_H37Rv SRVVLTHDIAQRDNLRVGRHDGVAAVIEKLKGHPLFAHITLLRSERSPIA
MAV_1217|M.avium_104 SRVVLTHDIAQRDNLRVGRHDGVAAVIEKLKGHPLFAHITLLRSERSPIA
MLBr_01951|M.leprae_Br4923 SRVVLTHDIAQRDNLRVGRHDGVAGVIEKLKGHPLFAHVTLQRSERSPVA
MMAR_4372|M.marinum_M SRVVLTHDIAQRDNLRVGRHDGIVAVIEKLKGHPLFAHITLLRSERSPIA
MAB_1239|M.abscessus_ATCC_1997 SRVVLTHDVAQRDNLRVGRHDGVAAVIEKLKGHPLFAHVTLVRSERSPIA
MUL_3621|M.ulcerans_Agy99 SKVVVTGDVTQVD-LPGGARSGLRAAVDILD-DIDDIHIAELNSADVVRH
*:**:* *::* * * * :.*: ..:: *. . *:: .*
Mvan_4652|M.vanbaalenii_PYR-1 ALVTEMLEEISPGA-LP-----------------
Mflv_2062|M.gilvum_PYR-GCK ALVTEMLEEISPGA-LP-----------------
MSMEG_5247|M.smegmatis_MC2_155 ALVTEMLEEISPGA-LP-----------------
TH_2158|M.thermoresistible__bu ALVTEMLEEFSPGAPLP-----------------
Mb1125|M.bovis_AF2122/97 ALVTEMLEEITGPR--------------------
Rv1095|M.tuberculosis_H37Rv ALVTEMLEEITGPR--------------------
MAV_1217|M.avium_104 ALVTEMLEEIAGPH--------------------
MLBr_01951|M.leprae_Br4923 ALVTEMFEEIAGPH--------------------
MMAR_4372|M.marinum_M ALVTEMLEEIAGPH--------------------
MAB_1239|M.abscessus_ATCC_1997 ALVTEMLEEFGPGLTA------------------
MUL_3621|M.ulcerans_Agy99 RLVSEIVDAYARYEEPGSGMNRAARRASGTRNRR
**:*:.: