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MRPSHRQLPHPRTGDLFTSPVRPGSGWPGDPATRRTAVAATSADVVTMAAAARSLSQLDAEISVCRACPR LVQWREDVAVEKRRSYADQPYWGRPAPGFGSPRPRIFVVGLAPAAHGANRTGRVFTGDRSGDFLFGSLYR TGLANQQTVTDSADGLVLNDIRVAAAVRCAPPGNAPTPAERSTCAPWLDAEWRLTAGHVRVIVALGGFAW QVALAMIRRAGGAVGAPAPKFGHGVTATLQTPAGDVALLGCYHPSQQNTFTGRLTPAMMDDIFATALAIS RAE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4459 | - | - | 100% (284) | uracil-DNA glycosylase superfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1289 | - | 1e-106 | 65.47% (278) | hypothetical protein Mb1289 |
| M. gilvum PYR-GCK | Mflv_2236 | - | 1e-128 | 76.24% (282) | uracil-DNA glycosylase superfamily protein |
| M. tuberculosis H37Rv | Rv1259 | - | 1e-106 | 65.47% (278) | hypothetical protein Rv1259 |
| M. leprae Br4923 | MLBr_01105 | - | 6e-85 | 64.63% (229) | hypothetical protein MLBr_01105 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4181 | - | 1e-106 | 67.90% (271) | hypothetical protein MMAR_4181 |
| M. avium 104 | MAV_1407 | - | 1e-103 | 64.84% (273) | uracil-DNA glycosylase superfamily protein |
| M. smegmatis MC2 155 | MSMEG_5031 | - | 1e-111 | 70.50% (278) | uracil-DNA glycosylase superfamily protein |
| M. thermoresistible (build 8) | TH_2407 | - | 1e-115 | 71.85% (270) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4483 | - | 1e-107 | 67.53% (271) | hypothetical protein MUL_4483 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1289|M.bovis_AF2122/97 MNIAAESSAKPVWGPPNFCAAAARMQDVRVLMHPKTGRAFRSPVEPGSGW
Rv1259|M.tuberculosis_H37Rv MNIAAESSAKPVWGPPNFCAAAARMQDVRVLMHPKTGRAFRSPVEPGSGW
MLBr_01105|M.leprae_Br4923 --------------------------------------------------
MAV_1407|M.avium_104 ------------------------MQDVGVLEHPRTGQAFDSPVPAGSGW
MMAR_4181|M.marinum_M ------------------------MQDDRVLTHPRTGQPFGSPVRPGTGW
MUL_4483|M.ulcerans_Agy99 ------------------------MQDDRVLTHPRTGQPFGSPVRPGTGW
Mvan_4459|M.vanbaalenii_PYR-1 ----------------------MMRPSHRQLPHPRTGDLFTSPVRPGSGW
Mflv_2236|M.gilvum_PYR-GCK ----------------------MMTGPRARLPHPRTGDLFETPVRPGRGW
TH_2407|M.thermoresistible__bu ----------------------------VTHPHPRTGAVFESPVPPGSGW
MSMEG_5031|M.smegmatis_MC2_155 ---------------MGPIFGHSGRVSPQLLPHPRTGQLFPSPVPPGTGW
Mb1289|M.bovis_AF2122/97 PGDPATPQTPVAADAAQVSALAGGAGSICELNALISVCRACPRLVSWREE
Rv1259|M.tuberculosis_H37Rv PGDPATPQTPVAADAAQVSALAGGAGSICELNALISVCRACPRLVSWREE
MLBr_01105|M.leprae_Br4923 -------------------MLSGGAGSIPELNAQISVCRACPRLVDWREE
MAV_1407|M.avium_104 PGDPATPQTPVAADADQVIALARHAGAIPELDALVSVCRACPRLVEWREE
MMAR_4181|M.marinum_M PGDPASSQTPVAAEAARVAELAGRAGSIVELDAAISVCRACPRLVTWREE
MUL_4483|M.ulcerans_Agy99 PGDPASSQTPVAAEAARVAELAGRAGSIAELDAAISVCRACPRLVTWREE
Mvan_4459|M.vanbaalenii_PYR-1 PGDPATRRTAVAATSADVVTMAAAARSLSQLDAEISVCRACPRLVQWRED
Mflv_2236|M.gilvum_PYR-GCK PGDPATSRTAVASNPAQVTALAAAAKNLRQLDAGVSVCRACPRLVEWREE
TH_2407|M.thermoresistible__bu PGDPATPHTAVAANAAQVQALAGAVETIEELDALVSVCRACPRLVQWREE
MSMEG_5031|M.smegmatis_MC2_155 PGDPATPSTPVAKTPAQVRRLAASAKTLDDLDAMISVCRACPRLVAWREE
:: . : :*:* :********** ***:
Mb1289|M.bovis_AF2122/97 VAVVKRRAFADQPYWGRPVPGWGSKRPRLLILGLAPAAHGANRTGRMFTG
Rv1259|M.tuberculosis_H37Rv VAVVKRRAFADQPYWGRPVPGWGSKRPRLLILGLAPAAHGANRTGRMFTG
MLBr_01105|M.leprae_Br4923 VAVVKRRAFADQPYWGRPVPGWGSEQPRLLIVGLAPAAHGANRTGRMFTG
MAV_1407|M.avium_104 VAVVKRRAFADQPYWGRPVPSWGSARPRLLIVGLAPAAHGANRTGRMFTG
MMAR_4181|M.marinum_M VAVAKRRAFADQPYWGRPVPGWGSERPWLLIVGLAPAAHGANRTGRMFTG
MUL_4483|M.ulcerans_Agy99 VAVAKRRAFADQPYWGRPVPGWGSERPWLLIVGLAPAAHGANRTGRMFTG
Mvan_4459|M.vanbaalenii_PYR-1 VAVEKRRSYADQPYWGRPAPGFGSPRPRIFVVGLAPAAHGANRTGRVFTG
Mflv_2236|M.gilvum_PYR-GCK AASVKRKSYADQPYWGRPAPGFGSARPRILIVGLAPAAHGANRTGRVFTG
TH_2407|M.thermoresistible__bu AATVKRRSYADEPYWGRPIPGWGAVRPRILVVGLAPAAHGGNRTGRVFTG
MSMEG_5031|M.smegmatis_MC2_155 VAVTKRKSFADQPYWGRPATGFGPEAPRILIAGLAPAAQGANRTGRVFTG
.* **:::**:****** ..:*. * ::: ******:*.*****:***
Mb1289|M.bovis_AF2122/97 DRSGDQLYAALHRAGLVNSPVSVDAADGLRANRIRITAPVRCAPPGNSPT
Rv1259|M.tuberculosis_H37Rv DRSGDQLYAALHRAGLVNSPVSVDAADGLRANRIRITAPVRCAPPGNSPT
MLBr_01105|M.leprae_Br4923 DRSGDQLYAALHRAGLVNLPISMDAADGLQANQIRITAPVRCAPPGNAPT
MAV_1407|M.avium_104 DRSGDQLYAALYRAGLVNQPTSVDAADGLRTKHIRIVAPVHCAPPANAPT
MMAR_4181|M.marinum_M DRSGDQLYAALHRAGLVSQPTSVDAADGLRAERIRIVAPVRCAPPANAPT
MUL_4483|M.ulcerans_Agy99 DRSGDQLYAALHRAGLVSQPTSVDAADGLRAEPIRIVAPVRCAPPANAPT
Mvan_4459|M.vanbaalenii_PYR-1 DRSGDFLFGSLYRTGLANQQTVTDSADGLVLNDIRVAAAVRCAPPGNAPT
Mflv_2236|M.gilvum_PYR-GCK DRSGDFLFASLHRSGLANQSTCTDSADGLELNDVRVAAAVRCAPPDNAPS
TH_2407|M.thermoresistible__bu DRSGDFLFASLHRVGLANQAECVDAADGLELYDTRLAAAVRCAPPGNAPS
MSMEG_5031|M.smegmatis_MC2_155 DRSGDFLFAALHRAGLANQAVCVDAADGMRLIDTRMAAAVRCAPPGNAPE
***** *:.:*:* **.. *:***: *:.*.*:**** *:*
Mb1289|M.bovis_AF2122/97 PAERLTCSPWLNAEWRLVSDHIRAIVALGGFAWQVALRLA----GASGTP
Rv1259|M.tuberculosis_H37Rv PAERLTCSPWLNAEWRLVSDHIRAIVALGGFAWQVALRLA----GASGTP
MLBr_01105|M.leprae_Br4923 QAEWVTCSPWLEAEWRLVSEYVRAIVALGGFAWQIVLRLP----GVSAMR
MAV_1407|M.avium_104 PVERDTCWPWLQAEWRLISEHVRVVVALGGFGWQIALRLP----GVPAAR
MMAR_4181|M.marinum_M PAERKTCAPWLDAEWRLVSHDVRVIVALGGFAWKVALGLP----GSLGAP
MUL_4483|M.ulcerans_Agy99 PAERKTCAPWLDAEWRLVSHDVRVIVALGGFAWKIALGLP----GSLGAP
Mvan_4459|M.vanbaalenii_PYR-1 PAERSTCAPWLDAEWRLTAGHVRVIVALGGFAWQVALAMIRRAGGAVGAP
Mflv_2236|M.gilvum_PYR-GCK PAERTTCAPWLDAEYRLTGTDVRVIVALGGFAWQVVLAMVRRTGGTVPVP
TH_2407|M.thermoresistible__bu PAERATCAPWLHAEWRLTGPYVRVVVALGGFAWRAALQMI----GDVPRP
MSMEG_5031|M.smegmatis_MC2_155 PAERATCAPWLAAEWRLVGPSVAVIVALGGFAWRAALELI----ADRPKP
.* ** *** **:** . : .:******.*: .* : .
Mb1289|M.bovis_AF2122/97 KPRFGHGVVTELGAG---VRLLGCYHPSQQNMFTGRLTPTMLDDIFREAK
Rv1259|M.tuberculosis_H37Rv KPRFGHGVVTELGAG---VRLLGCYHPSQQNMFTGRLTPTMLDDIFREAK
MLBr_01105|M.leprae_Br4923 KPRFSHGVVAQLYAG---VRLLGCYHPSQQNMFTGRLTPAMLDDIFRDAK
MAV_1407|M.avium_104 KPRFGHGVVAELAPG---VRLLGCYHPSQQNMFTGRLTPAMLDDVFRDAK
MMAR_4181|M.marinum_M RPRFGHGVVAELGSG---VQLLGCYHPSQQNMFTGRLTPAMLDDVFRDAK
MUL_4483|M.ulcerans_Agy99 RPRFGHGVVAELGSG---VQLLGCYHPSQQNMFTGRLTPAMLDDVFRDAK
Mvan_4459|M.vanbaalenii_PYR-1 APKFGHGVTATLQTPAGDVALLGCYHPSQQNTFTGRLTPAMMDDIFATAL
Mflv_2236|M.gilvum_PYR-GCK APKFGHAATAELATPRGAVTVLGCFHPSQQNTFTGRLTPDMMDAVFATAR
TH_2407|M.thermoresistible__bu APKFGHGATAELTGPHGPVTLIGCYHPSQQNTFTGKLTPAMLDDVFTLAI
MSMEG_5031|M.smegmatis_MC2_155 APKFGHGATATLTTAYGDVTLLGCYHPSQQNTFTGRLTPDMLDDIFELAK
*:*.*...: * * ::**:****** ***:*** *:* :* *
Mb1289|M.bovis_AF2122/97 KLAGIE---------------------
Rv1259|M.tuberculosis_H37Rv KLAGIE---------------------
MLBr_01105|M.leprae_Br4923 KLAGI----------------------
MAV_1407|M.avium_104 GLAGIK---------------------
MMAR_4181|M.marinum_M KLGGIG---------------------
MUL_4483|M.ulcerans_Agy99 KLGGIG---------------------
Mvan_4459|M.vanbaalenii_PYR-1 AISRAE---------------------
Mflv_2236|M.gilvum_PYR-GCK TLSK-----------------------
TH_2407|M.thermoresistible__bu SACQRSLSDRDHAEIAGRREGDGDARR
MSMEG_5031|M.smegmatis_MC2_155 QIGNERDGQ------------------