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MAESSIVVRPEPKDSGSYSAASRLQAAGLVPAIAVFERAAAAVPLPQPPQPIVIADYGAGNGLNSLLPIG AATAVLRKRTRPEHSVLVAHTDRPDNDFTALFHTVENDPDTYLHKDKATFVSAIGRSFYSQILPSNSVHL GWSAWAIHWLTRVPCGIEGHIQVDFCSDEGVRAAYARQAAHDWHEFIAFRGRELCPGGRLVVMTTAVGDD GDSGFRPLMSVLLDTLDELAGAGLLTADEVAQMCLPTMARRAADFVAPFAPSGRFERLEIEHLEIFDATD RFWERYRVDSDASTFGARWAGFARASLFPALARALDDGGADQRTAEFFDRLEKGIAERLAASPEPTRIPL AHVVLVKRPRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3770 | - | - | 100% (361) | hypothetical protein Mvan_3770 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2764 | - | 1e-163 | 77.50% (360) | hypothetical protein Mflv_2764 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3356 | - | 1e-122 | 57.89% (361) | hypothetical protein MMAR_3356 |
| M. avium 104 | MAV_2179 | - | 1e-116 | 57.46% (355) | hypothetical protein MAV_2179 |
| M. smegmatis MC2 155 | MSMEG_4347 | - | 1e-113 | 57.75% (355) | hypothetical protein MSMEG_4347 |
| M. thermoresistible (build 8) | TH_1502 | - | 1e-121 | 60.66% (361) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1287 | - | 1e-117 | 56.90% (355) | hypothetical protein MUL_1287 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3770|M.vanbaalenii_PYR-1 ------MAESSIVVRPEPKDSGSYSAASRLQAAGLVPAIAVFERAAAAVP
Mflv_2764|M.gilvum_PYR-GCK -----MMAESSIVVRPEPAGSQFYSAASRLQASGLVPAIEVFERAAAEVP
MSMEG_4347|M.smegmatis_MC2_155 ------MPKFRVAVDPEPDDPTPKMRAPRPHAAGLNSAIALLEEAARTVP
TH_1502|M.thermoresistible__bu MKPEGQLPESSAVVRPVPVGSSTYTARSRLQAAGLAEAIRLFEQAAGAVA
MMAR_3356|M.marinum_M MPREIRLPESSVVVRPAPMESATYSQSSRLQAAGLSPAITLFEKAAQTVP
MUL_1287|M.ulcerans_Agy99 ------------MVRPAPMESATYSQSSRLQAAGLSPAITLFEKAAQTVP
MAV_2179|M.avium_104 ------------MVRPEP----TYTEASRLRAAGLAKAIAQFERAAEQVA
* * * .* :*:** ** :*.** *.
Mvan_3770|M.vanbaalenii_PYR-1 LPQPPQPIVIADYGAGNGLNSLLPIGAATAVLRKRTRPEHSVLVAHTDRP
Mflv_2764|M.gilvum_PYR-GCK LPKPPQPIVIADYGAANGLGSLLPISAAIAVLRNRTRPEHSVLVAHTDRP
MSMEG_4347|M.smegmatis_MC2_155 LPEAPYPIVIADYGVGTGRNSMRPIAAAIAALRGRTRPEHSVLVTHTDNA
TH_1502|M.thermoresistible__bu LPRPPQPIVIADYGAATGHNSLRPICAAIDVLRSRTSADHSVLVTHTDVP
MMAR_3356|M.marinum_M LPDAPQPVVIADYGVATGHNSLKPMMAAINALRRRIREDRAIMVAHTDVP
MUL_1287|M.ulcerans_Agy99 LPDAPQPVVIADYGVATGHNSLNPMMAAINALRRRIREDRATMVAHTDVP
MAV_2179|M.avium_104 LPKAPQPIVVADYGAANGHNSLKPLSAAVSVLRRRTRPDHAILVAHTDLP
** .* *:*:****...* .*: *: ** .** * ::: :*:*** .
Mvan_3770|M.vanbaalenii_PYR-1 DNDFTALFHTVENDPDTYLHKDKATFVSAIGRSFYSQILPSNSVHLGWSA
Mflv_2764|M.gilvum_PYR-GCK DNDFTALFDTLENDPDSYLHKDRATYVSAVGRSFYRQIIPSNSVNLGWSA
MSMEG_4347|M.smegmatis_MC2_155 DNDFTAVFRGLADNPDSYLRRDTSTYPSAVGRSFYTQILPSKSVHVGWSA
TH_1502|M.thermoresistible__bu KNDFSALFDTLSNDPDSYLAHDPATFTSAVGRSFFDQILPSNSVNLGWSA
MMAR_3356|M.marinum_M DNDFTALFRTLADDPDSYLHHDSASFASAVGRSFYTQILPSNTVSLGWSS
MUL_1287|M.ulcerans_Agy99 DNDVTALFRTLADDPDSYLHHDSASFASAVGRSFYTQILPSNTVSLGWSS
MAV_2179|M.avium_104 GNDFSALFDTVADDPESYLHADAATFTSAIGRSFYNQIVPSRTVNLGWTS
**.:*:* : ::*::** * ::: **:****: **:**.:* :**::
Mvan_3770|M.vanbaalenii_PYR-1 WAIHWLTRVPCG---IEGHIQVDFCSDEGVRAAYARQAAHDWHEFIAFRG
Mflv_2764|M.gilvum_PYR-GCK WAIDWLTQTPCG---IDGQLQVSFTSDADVRTAYGRQAARDWHEFVAFRG
MSMEG_4347|M.smegmatis_MC2_155 WAIVRVGRMPMP---VPDHVAASFSGDPQVVAAYARQAAFDWHEFVAFRG
TH_1502|M.thermoresistible__bu WAIQFLSRVPEP---VPDHLVAAGSSDDRVRTAYARQAARDWQDFLAFRG
MMAR_3356|M.marinum_M WAIQWLSRIPAGAPELTDHVQVAYSKDERARAAYAHQAATDWQDFLAFRG
MUL_1287|M.ulcerans_Agy99 WAIQWLSRIPAGAPELTDHVQVAYSKDERARAAYAHQAATDWQDFLAFRG
MAV_2179|M.avium_104 WATQWLSRTPG---AVPDHVHVSCSRDDAVLAAYADQAALDWHNFVAFRG
** : : * : .:: . * . :**. *** **::*:****
Mvan_3770|M.vanbaalenii_PYR-1 RELCPGGRLVVMTTAVGDDG---DSGFRPLMSVLLDTLDELAGAGLLTAD
Mflv_2764|M.gilvum_PYR-GCK RELCPGGRLVVMTQGVGEDG---AGGFEPMMTAMLDTLEEMAGAQVLTAD
MSMEG_4347|M.smegmatis_MC2_155 RELASGAQLVVLTAALGDDG---DFGYRPLFAAVMDTLRELTADGVLRQD
TH_1502|M.thermoresistible__bu RELAPHGRLLVMTMALHDSG---EFGHRPLLAALRDTLAELRDDGVLTDD
MMAR_3356|M.marinum_M RELCPGGRLVVLTMALDEHG---HFGYRPMNDALVAALNDQVRDGLLRPE
MUL_1287|M.ulcerans_Agy99 RELCPGGRLVVLTMALDEHG---HFGYRPMNDALVAAFNDQVRDGLLRPE
MAV_2179|M.avium_104 RELAPEGRLVALTLAADEEDGRCSAGFAALLDAIVEALEDQRRDGLLRPD
***.. .:*:.:* . : . *. .: .: :: : :* :
Mvan_3770|M.vanbaalenii_PYR-1 EVAQMCLPTMARRAADFVAPFAPSGRFERLEIEHLEIFDATDRFWERYRV
Mflv_2764|M.gilvum_PYR-GCK EVGRMCIPTVARSAADFRAPFAPSGRFEGLEIEHLEIFEASDRFWDRYRI
MSMEG_4347|M.smegmatis_MC2_155 ELHRMSLPIVGRRANDFMAPFAPSGRFERLSISHLEVYDAEDVIYSSYQK
TH_1502|M.thermoresistible__bu QWRRMVLPIVGRSAADFVAPFAPSGRYERLEVEHLEVFDAQDRYYAQYRV
MMAR_3356|M.marinum_M ELRRMAIPVVARAEKDLRAPFAPRGWFEGLTIEQLDVFNAEDRFWAAFQS
MUL_1287|M.ulcerans_Agy99 ELRRMAIPVVARAEKDLRAPFAPRGWFEGLTIEQLDVFNAEDRFWAAFQS
MAV_2179|M.avium_104 ELQRMTIPTFARSEKDFRAPFAPKGRFEGLMVEQLEIFNAEDRFWARFQA
: :* :* ..* *: ***** * :* * :.:*::::* * : ::
Mvan_3770|M.vanbaalenii_PYR-1 DSDASTFGARWAGFARASLFPALARALDDGGADQRTAEFFDRLEKGIAER
Mflv_2764|M.gilvum_PYR-GCK DQDAHAFGARWAGFARSSVFSALAQALD--GPAQRAADFFDVLEKGIADR
MSMEG_4347|M.smegmatis_MC2_155 DRDTDVFGLRWADFCRFTFFSDLCTALD--DDAARCTQFQDRLHAGIAAR
TH_1502|M.thermoresistible__bu DGDAAAFGAQWGAFCRAAVLPALLATAP--ADPALVG---DRLEAGVAAR
MMAR_3356|M.marinum_M DGDAESFGAQWAGFARAALFPTLAAALDCGTGDPRATAFIEQLEASVADR
MUL_1287|M.ulcerans_Agy99 DGDAEASGAQWAGFARAALFPTLAAALDCGTGDPRATAFIEQLEASVADR
MAV_2179|M.avium_104 DHDAEAFGAQWAAFARSALFPALVAGLDDGIRDPRAPRFVEQLQSAIAQR
* *: * :*. *.* :.:. * : *. .:* *
Mvan_3770|M.vanbaalenii_PYR-1 LAASPEPTRIPLAHVVLVKRPRP--
Mflv_2764|M.gilvum_PYR-GCK MAASPGQTRIPLAHVVLHKRPKT--
MSMEG_4347|M.smegmatis_MC2_155 LSAQPEQMRIPLAQLVLERRRR-SG
TH_1502|M.thermoresistible__bu MAADPQESQLPMAQLVLVKRPHPTG
MMAR_3356|M.marinum_M LASQPEPMRIPLASLVLAKRA----
MUL_1287|M.ulcerans_Agy99 LASQPEPMRVPLASLVLAKRA----
MAV_2179|M.avium_104 LSSAPEPMRIPQALLVLVKREAAQ-
::: * ::* * :** :*