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TVLLLRHGRSTSNTANTLAGRSEGVDLDDRGREQASALVDRLESLPIRAIVRSPLLRCERTVEPLAAALG LQPLVDDRITEVDYGAWTGRKIVELVKEPLWAVIQQQPSAAVFPEGEGLAGVQARAVAAVREHDRRLADE HGADVLWIACTHGDVIKSVLADALGTHLDSFQRINADPASVSVVRYTPVRPFVIHVNHTGVALNAALSAP PSTGESETGGVPSGDAVVGGSTD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3482 | - | - | 100% (234) | phosphoglycerate mutase |
| M. vanbaalenii PYR-1 | Mvan_3618 | - | 1e-13 | 30.69% (189) | bifunctional RNase H/acid phosphatase |
| M. vanbaalenii PYR-1 | Mvan_3924 | - | 7e-10 | 28.90% (173) | phosphoglycerate mutase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2159c | - | 4e-94 | 71.31% (237) | hypothetical protein Mb2159c |
| M. gilvum PYR-GCK | Mflv_3044 | - | 1e-112 | 86.32% (234) | phosphoglycerate mutase |
| M. tuberculosis H37Rv | Rv2135c | - | 4e-94 | 71.31% (237) | hypothetical protein Rv2135c |
| M. leprae Br4923 | MLBr_01298 | - | 4e-92 | 65.20% (250) | hypothetical protein MLBr_01298 |
| M. abscessus ATCC 19977 | MAB_2109 | - | 4e-92 | 69.23% (234) | putative phosphoglycerate/bisphosphoglycerate mutase |
| M. marinum M | MMAR_3115 | - | 8e-97 | 69.35% (248) | hypothetical protein MMAR_3115 |
| M. avium 104 | MAV_2357 | - | 1e-94 | 66.29% (264) | hypothetical protein MAV_2357 |
| M. smegmatis MC2 155 | MSMEG_4193 | - | 1e-100 | 75.21% (234) | phosphoglycerate mutase family protein |
| M. thermoresistible (build 8) | TH_2363 | - | 1e-106 | 78.21% (234) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2365 | - | 1e-95 | 68.95% (248) | hypothetical protein MUL_2365 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3482|M.vanbaalenii_PYR-1 MTVLLLRHGRSTSNTANTLAGRSEGVDLDDRGREQASALVDRLESLPIRA
Mflv_3044|M.gilvum_PYR-GCK MTVLLVRHGRSTSNTAHTLAGRSEGVDLDDRGREQASELVERLGGLPIRA
TH_2363|M.thermoresistible__bu MTVILLRHGRSTANTSHTLAGRTAGVDLDEKGREQAAALVDRIGELPIRA
MSMEG_4193|M.smegmatis_MC2_155 MTVILLRHGRSTSNTAHTLAGRSDGVDLDDRGREQAEGVVSRIGDLPVRA
MAB_2109|M.abscessus_ATCC_1997 MTVILLRHGRSTSNVAHTLAGRSPGVELDEKGQSQARGVVDRLSAVAVQA
Mb2159c|M.bovis_AF2122/97 MTVILLRHARSTSNTAGVLAGRS-GVDLDEKGREQATGLIDRIGDLPIRA
Rv2135c|M.tuberculosis_H37Rv MTVILLRHARSTSNTAGVLAGRS-GVDLDEKGREQATGLIDRIGDLPIRA
MLBr_01298|M.leprae_Br4923 MTVILLRHGRSTSNTAGVLAGRADGVDLDDRGREQAVGLIDRIAELPIRA
MAV_2357|M.avium_104 MTVILLRHGRSTSNTAGVLAGRSEGVDLDDKGREQAAGLIDWIGDLPIRA
MMAR_3115|M.marinum_M MTVILLRHGRSTSNTAGILAGRSEGVDLDDKGRQQASGLIDRIGDLPVRA
MUL_2365|M.ulcerans_Agy99 MTVILLRHGRSTSNTAGILAGRSEGVDLDDKGRQQASGLIDRIGDLPVRA
***:*:**.***:*.: ****: **:**::*:.** ::. : :.::*
Mvan_3482|M.vanbaalenii_PYR-1 IVRSPLLRCERTVEPLAAALGLQPLVDDRITEVDYGAWTGRKIVELVKEP
Mflv_3044|M.gilvum_PYR-GCK IVRSPLLRCERTVEPLAAALGVTPVVEDRIVEVDYGAWTGRKIGELVKEP
TH_2363|M.thermoresistible__bu IVRSPLLRCRRTVEPLAAALGLEPVVDDRLIEVDYGAWTGRKLSELVKEP
MSMEG_4193|M.smegmatis_MC2_155 IVRSPMLRCERTIDPLATALGLQPIVDERLTEVDYGSWTGRKISDLLKEP
MAB_2109|M.abscessus_ATCC_1997 VVTSPLLRCEQTVAPLAAALELIPIVEDRLAEVDYGQWTGREIAELLAEP
Mb2159c|M.bovis_AF2122/97 VASSPMLRCQRTVEPLAEALCLEPLIDDRFSEVDYGEWTGRKIGDLVDEP
Rv2135c|M.tuberculosis_H37Rv VASSPMLRCQRTVEPLAEALCLEPLIDDRFSEVDYGEWTGRKIGDLVDEP
MLBr_01298|M.leprae_Br4923 VVCSPLLRCRRTINPLAETLCLEPFIDDRLSEVDYGEWTGRSIGDLAKEP
MAV_2357|M.avium_104 LISSPLLRCRRTLEPLADTLCLAPLVDDRLAEVDYGEWTGRKIGELVSEP
MMAR_3115|M.marinum_M VVSSPLLRCRTTVEPLADALCLEPLIEERLAEVDYGDWTGRKIAELVNEP
MUL_2365|M.ulcerans_Agy99 VVSSPLLRCRTTVEPLADALCLEPLVEERLAEVDYGDWTGRKIAELVNEP
: **:***. *: *** :* : *.:::*: ***** ****.: :* **
Mvan_3482|M.vanbaalenii_PYR-1 LWAVIQQQPSAAVFPEGEGLAGVQARAVAAVREHDRRLADEHGADVLWIA
Mflv_3044|M.gilvum_PYR-GCK LWAVVQQQPSAAVFPDGEGLAQVQARAVAAVREHDRRLAEEHGADVLWVA
TH_2363|M.thermoresistible__bu LWAVVQQQPSAAVFPDGEGLAQVQARAVAAVREHDRRLAEEHGADVLWLA
MSMEG_4193|M.smegmatis_MC2_155 LWSVVQAQPSAAVFPEGEGLAQVQARAVAAVRERDRALAAEHGADVLWVA
MAB_2109|M.abscessus_ATCC_1997 LWKIVQQQPSAARFPDGEGLAQVQARAVAAVREHDRRLSEEHGGDCIWVA
Mb2159c|M.bovis_AF2122/97 LWRVVQAHPSAAVFPGGEGLAQVQTRAVAAVREHDRRLADQHGHDVLWLA
Rv2135c|M.tuberculosis_H37Rv LWRVVQAHPSAAVFPGGEGLAQVQTRAVAAVREHDRRLADQHGHDVLWLA
MLBr_01298|M.leprae_Br4923 LWQVVQAHPSAAVFPSGEGLAQVQVRAVAAIREYDRRFTSEHGGDTLWVA
MAV_2357|M.avium_104 LWKVVQAHPSAAVFPGGEGLAQVQARAVAAVREHDRRLAAEHGADALWVA
MMAR_3115|M.marinum_M LWRVVQAHPSAAVFPGGEGLAQVQARAVAAVREHDRRLAEEYGGDALWLA
MUL_2365|M.ulcerans_Agy99 LWRVVQAHPSAAVFPGGEGLAQVQARAVAAVCEHDRRLAEKYGGDALWLA
** ::* :**** ** ***** **.*****: * ** :: ::* * :*:*
Mvan_3482|M.vanbaalenii_PYR-1 CTHGDVIKSVLADALGTHLDSFQRINADPASVSVVRYTPVRPFVIHVNHT
Mflv_3044|M.gilvum_PYR-GCK CTHGDVIKSVLADALGSHLDSFQRINADPASVSVVRYTPFRPFVIHVNHT
TH_2363|M.thermoresistible__bu CSHGDVIKAVLADALGTHLDSFQRIGADPASMSVIRYTAVRPFVMHVNHT
MSMEG_4193|M.smegmatis_MC2_155 CTHGDVIKAVLADALGVHLDGFQRITADPASMSVVRYTELRPFVMHINHT
MAB_2109|M.abscessus_ATCC_1997 CTHGDVIKSVLADALGTHLDAFQRIVADPASMSVVRYTELRPFVLHMNHT
Mb2159c|M.bovis_AF2122/97 CTHGDVIKAVIADAFGMHLDSFQRITADPGSVSVVRYTQLRPFVLHVNHT
Rv2135c|M.tuberculosis_H37Rv CTHGDVIKAVIADAFGMHLDSFQRITADPGSVSVVRYTQLRPFVLHVNHT
MLBr_01298|M.leprae_Br4923 CTHGDVIKAVIADAFGMHLDSFQRVIADPGSVSVIRYTQLRPFVLHVNHT
MAV_2357|M.avium_104 CTHGDVIKAVIADAYGIHLDGFQRVTADPASISVIRYTELRPFVLHVNHT
MMAR_3115|M.marinum_M CTHGDVIKAVVADAYGMHLDSFQRVTADPASASVIRYTQLRPFVLHVNHT
MUL_2365|M.ulcerans_Agy99 CTHGDVIKAVVADAYGMHLDSFQRVTADPASASVIRYTQLRPFVLHVNHT
*:******:*:*** * ***.***: ***.* **:*** .****:*:***
Mvan_3482|M.vanbaalenii_PYR-1 GVALNAALSAPPSTGESET------------------------------G
Mflv_3044|M.gilvum_PYR-GCK GGALNPALSAPPPEGKD---------------------------------
TH_2363|M.thermoresistible__bu GAQLTAGLLPKPAQPDQPQ------------------------------G
MSMEG_4193|M.smegmatis_MC2_155 GPQLSAGLAAEP--------------------------------------
MAB_2109|M.abscessus_ATCC_1997 GPDLSSALSARPPEKSAG--------------------------------
Mb2159c|M.bovis_AF2122/97 GARLAPALQAAASAQGASP---------------------------EPNA
Rv2135c|M.tuberculosis_H37Rv GARLAPALQAAASAQGASP---------------------------EPNA
MLBr_01298|M.leprae_Br4923 GAQLSSALRAAMKPSGESHSDSCGER--------------SGEIRNEPDA
MAV_2357|M.avium_104 GARLSAPLRAGPAPPPDQHDDQHDDQDHDTGDKAHTDPKSNGESQAAPAT
MMAR_3115|M.marinum_M GARLSAGLRAGLPPKAAPDKPDEEPD----------------KVQTESVG
MUL_2365|M.ulcerans_Agy99 GARLSAGLRAGLPPKAAPDKPDEEPD----------------KVQTESVG
* * . * .
Mvan_3482|M.vanbaalenii_PYR-1 GVPSGDAVVGGSTD
Mflv_3044|M.gilvum_PYR-GCK -VPTGDAVVGGSTE
TH_2363|M.thermoresistible__bu DIPAEDAVVGGSTE
MSMEG_4193|M.smegmatis_MC2_155 ---KTDAVVGGSTD
MAB_2109|M.abscessus_ATCC_1997 --DASDATVGGTTD
Mb2159c|M.bovis_AF2122/97 AVPPGDAVIGGSTD
Rv2135c|M.tuberculosis_H37Rv AVPPGDAVIGGSTD
MLBr_01298|M.leprae_Br4923 AVPSGDAVLGGSAD
MAV_2357|M.avium_104 SVPSSDAVVGGSTD
MMAR_3115|M.marinum_M GVPSGDAVVGGSTD
MUL_2365|M.ulcerans_Agy99 GVPSGDAVVGGSTD
**.:**:::