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RVAPVPRAERTRMRPSTLAKTAGAAFATAAAGGLATRSAVDSKWYRRLRKPGFQPPRAAFPIAWNVLYTD IAAVSASTIDTLNDRGETDRARAYTRALALNLALNAGWSWVFFNRRMLGPAAVVAAGLTVSSADLARRAG QVNAPAGAALAAYPLWCVFATALSTRIWQLNR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3382 | - | - | 100% (173) | TspO and MBR like proteins |
| M. vanbaalenii PYR-1 | Mvan_0268 | - | 3e-15 | 36.53% (167) | TspO and MBR like proteins |
| M. vanbaalenii PYR-1 | Mvan_2908 | - | 3e-05 | 27.95% (161) | hypothetical protein Mvan_2908 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3142 | - | 1e-63 | 82.01% (139) | TspO- and MBR-like protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2223 | - | 4e-09 | 29.22% (154) | putative TspO/MBR-related protein precursor |
| M. marinum M | MMAR_1672 | - | 4e-43 | 53.12% (160) | tryptophan-rich sensory protein |
| M. avium 104 | MAV_3896 | - | 6e-12 | 51.56% (64) | peripheral-type benzodiazepine receptor |
| M. smegmatis MC2 155 | MSMEG_1131 | - | 2e-53 | 62.50% (160) | tryptophan-rich sensory protein |
| M. thermoresistible (build 8) | TH_3201 | - | 1e-20 | 48.74% (119) | PUTATIVE glycosyl transferase, family 51 |
| M. ulcerans Agy99 | MUL_1908 | - | 1e-43 | 53.12% (160) | tryptophan-rich sensory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3382|M.vanbaalenii_PYR-1 MRVAPVPRAERTRMRPSTLAKTAGAAFATAAAGGLATRSAVDSKWYRRLR
Mflv_3142|M.gilvum_PYR-GCK ----------------------------------MATGPAVQSTWYRRLR
MSMEG_1131|M.smegmatis_MC2_155 -------------MRPITLAKTASAVIATGVVGGLASR-GSQTAWYQSLR
MMAR_1672|M.marinum_M -------------MNKSTLAGTALAVTAAAGSGSIASP-PRTSDWYARLR
MUL_1908|M.ulcerans_Agy99 -------------MNKSTLAGTALAVTAAAGSGSIASP-PRTSDWYARLR
MAV_3896|M.avium_104 -------------MNRSILGATSLAVAAAAGAGRLAGA-KAGPRWYARLR
TH_3201|M.thermoresistible__bu -------------MRLSTLATTAAAVALTGTVGGLATGPAARSRWFARLK
MAB_2223|M.abscessus_ATCC_1997 ---MTDRVSPRLPNDIPALGISLAAAAVAAGVGGLASA--NAAAQYGVLA
:* . : *
Mvan_3382|M.vanbaalenii_PYR-1 KPGFQPPRAAFPIAWNVLYTDIAAVSASTIDTLND---------------
Mflv_3142|M.gilvum_PYR-GCK KPGFQPPPKAFPIAWNILYSDIAAVSASTLDTLHD---------------
MSMEG_1131|M.smegmatis_MC2_155 KPSFQPPPAAFPIAWNLLYADIASTSAHTIDKFQE---------------
MMAR_1672|M.marinum_M KPSYQPPSVAFPMVWTTLYGDIAASSAVAIDRLNA---------------
MUL_1908|M.ulcerans_Agy99 KPSYQPPSVAFPMVWTTLYSDIAASSAVAIDRLNA---------------
MAV_3896|M.avium_104 QPAYQPPGAAFPLAWTTLYADIAATS------------------------
TH_3201|M.thermoresistible__bu KPGFQPPAQAFPIVWPILYTDIAGVSAATIDRLXXXPGEPPEEPANWFDR
MAB_2223|M.abscessus_ATCC_1997 QPSWAPPAWVFGPVWTVLYVLMGVAAWLVWRTRPP---------------
:*.: ** .* .* ** :. :
Mvan_3382|M.vanbaalenii_PYR-1 ---RGETDRARAYTRALALNLALNAGWSWVFFNRRMLG--PAAVVAAGLT
Mflv_3142|M.gilvum_PYR-GCK ---RGDTDQARAYTRALAVNLALNAGWSWVFFNRRQLG--PAAALAGALA
MSMEG_1131|M.smegmatis_MC2_155 ---QNRDDKARAYSVALAANLILNASWSWIFFNRGKLG--TAAIAAGALA
MMAR_1672|M.marinum_M ---TGQRDKARRYIGALSINLVLNAGWSWLFFRFHRLG--ASALGAAVLA
MUL_1908|M.ulcerans_Agy99 ---TGQRDKARRYIGALSINLVLNAGWSWLFFRFHRLG--ASALGAAVLA
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu INWRWVRRGLFAGAVALLVLPIITFVMAYLIVDVPRPGDIRTNQVSTILA
MAB_2223|M.abscessus_ATCC_1997 --------VPASALTAYGIQLVLNALWTPLFFGLGWRG--AALAEIAVLW
Mvan_3382|M.vanbaalenii_PYR-1 VSSADLARRAGQVNAPAGAALAAYPLWC---------------------V
Mflv_3142|M.gilvum_PYR-GCK VSSADLTRRAGAVNPPAGIALAAYPLWC---------------------A
MSMEG_1131|M.smegmatis_MC2_155 ASSADLTRRAVDAQGARGAILAPYPLWC---------------------T
MMAR_1672|M.marinum_M TSSADLVRRTADADRRAGLAMLPYAVWC---------------------A
MUL_1908|M.ulcerans_Agy99 TSSADLVRRTADADRRAGLAMLPYAVWC---------------------A
MAV_3896|M.avium_104 ---------------RGALALSPYPLWC---------------------G
TH_3201|M.thermoresistible__bu SDGSELARIVPPEGNRIDVNINQIPVHVRDAVMAAEDRDFYSNPGFSFTG
MAB_2223|M.abscessus_ATCC_1997 IALLVTIALFWVRSRAAAVLLLPYLVWT---------------------T
: :
Mvan_3382|M.vanbaalenii_PYR-1 FATALSTRIWQLNR------------------------------------
Mflv_3142|M.gilvum_PYR-GCK FATALSTRIWLLNR------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 FATVLSTRIWMLNRKR----------------------------------
MMAR_1672|M.marinum_M FATVLATHVWRLNR------------------------------------
MUL_1908|M.ulcerans_Agy99 FATVLATHVWRLNR------------------------------------
MAV_3896|M.avium_104 FATVLSTHIWRLNG------------------------------------
TH_3201|M.thermoresistible__bu FARAIGNNIFGGDVQGGSTITQQYVKNALVGSERVGVRGLIRKAKELVIS
MAB_2223|M.abscessus_ATCC_1997 FAACLNFAVWQLNTAAV---------------------------------
** : :: :
Mvan_3382|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1672|M.marinum_M --------------------------------------------------
MUL_1908|M.ulcerans_Agy99 --------------------------------------------------
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu TKMSRQWSKDQVMQSYLNIIYFGRGAYGVAAASRAYFDKPVEELNVAEGA
MAB_2223|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3382|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1672|M.marinum_M --------------------------------------------------
MUL_1908|M.ulcerans_Agy99 --------------------------------------------------
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu LLAALIQRPSTLDPAADPQGAETRWNWVLDGMVEIGALSPQERAAQVFPP
MAB_2223|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3382|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1672|M.marinum_M --------------------------------------------------
MUL_1908|M.ulcerans_Agy99 --------------------------------------------------
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu TVPPELARSQNQTTGPNGLIERQVTRELLELFNISEQALNTEGLQITTTI
MAB_2223|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3382|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1672|M.marinum_M --------------------------------------------------
MUL_1908|M.ulcerans_Agy99 --------------------------------------------------
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu DPQAQQAAVDAVETYLEGQDPDMRAAVVSIDPRTGAVKAYYGGSDANGYD
MAB_2223|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3382|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1672|M.marinum_M --------------------------------------------------
MUL_1908|M.ulcerans_Agy99 --------------------------------------------------
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu FAQAAVPTGSSFKVFALVAALEQGMGLGYQVDSSPLTVNGIEITNVEGSS
MAB_2223|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3382|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1672|M.marinum_M --------------------------------------------------
MUL_1908|M.ulcerans_Agy99 --------------------------------------------------
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu CGRCNIAEALKRSLNTSFYRLMLELKNGPEDVADAAHRAGIAESIPGIEH
MAB_2223|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3382|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1672|M.marinum_M --------------------------------------------------
MUL_1908|M.ulcerans_Agy99 --------------------------------------------------
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu TLSEDGKGGPPNNGIVLGQYQSRPIDMASAYATLANSGVYHRPHFVQKVV
MAB_2223|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3382|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1672|M.marinum_M --------------------------------------------------
MUL_1908|M.ulcerans_Agy99 --------------------------------------------------
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu NSEGQVLFDADQRDDDGEQRIEKDVADNVTAAMQPIAAYSNGHALAGGRP
MAB_2223|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3382|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1672|M.marinum_M --------------------------------------------------
MUL_1908|M.ulcerans_Agy99 --------------------------------------------------
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu SAAKTGTHQLGDTGENRDAWMVGYTPSLSTAVWVGTVDGNKPLRTKWGGK
MAB_2223|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3382|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1672|M.marinum_M --------------------------------------------------
MUL_1908|M.ulcerans_Agy99 --------------------------------------------------
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu IYGSGLPSDIWKATMDGALKGTERESFPKPGEIGGYAGVPQAPSPQRTSD
MAB_2223|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3382|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1672|M.marinum_M --------------------------------------------------
MUL_1908|M.ulcerans_Agy99 --------------------------------------------------
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu DDGTTTVTPPSETVIQPSVEVAPGITIPLGXAVSAVVRVRDAVVRPHLVA
MAB_2223|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3382|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1672|M.marinum_M --------------------------------------------------
MUL_1908|M.ulcerans_Agy99 --------------------------------------------------
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu EPPLTGRPDGTSRPGRRAPVRRCRNVDFRRDIGAPCAFHRDRRWLPADAV
MAB_2223|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3382|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1672|M.marinum_M --------------------------------------------------
MUL_1908|M.ulcerans_Agy99 --------------------------------------------------
MAV_3896|M.avium_104 --------------------------------------------------
TH_3201|M.thermoresistible__bu RAEPLGRGSPQRTGPGRAGGLLSGAAVRGTGVPSEPAHGGSVPRRAGGAD
MAB_2223|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3382|M.vanbaalenii_PYR-1 -------------------------------------------
Mflv_3142|M.gilvum_PYR-GCK -------------------------------------------
MSMEG_1131|M.smegmatis_MC2_155 -------------------------------------------
MMAR_1672|M.marinum_M -------------------------------------------
MUL_1908|M.ulcerans_Agy99 -------------------------------------------
MAV_3896|M.avium_104 -------------------------------------------
TH_3201|M.thermoresistible__bu DGADAPGAGRAPGAQRRVRHHPGGPDGGPRQPAAVSPLRGTTR
MAB_2223|M.abscessus_ATCC_1997 -------------------------------------------