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SGAAPPSGPPRPSAKYRDRVARTSSKTDSPKTGRLSGRFWKLLGASTDKDQARSMAQVHKAAEFDAKAAD LDDEQLRKAARLLELDDLADSTDVPQFLAIAREAAKRTTGLTPFDVQLQGALRMLAGDVVEMATGEGKTL SGAIAAAGYALAGRNVHVITINDYLARRDAEWMGPLIEAMGLTIGWITADSTAAERRAAYRCDITYASVN EIGFDVLRDQLVTDVDDLVSPNPDVALIDEADSVLVDEALVPLVLAGTSHRETPRLELIRLVGELDENTD FATDNDSRNVHLTEAGARKIEAALGGIDLYSEEHVATTLTEVNVALHAHVLLQRDVHYIVRDDAVHLINS SRGRIATLQRWPDGLQAAVEAKEGIETTETGEVLDTITVQALINRYPRVCGMTGTALAAGEQLRQFYKLG VSPIPPNKPNIRQDETDRVYVTIAAKNDAVIEHIAEVHETGQPVLVGTRDVAESEEIHRRLVKAGVPAVV LNAKNDAEEAAVIAEAGKLGAVTVSTQMAGRGTDIRLGGSDEEDHDRVAELGGLHVIGTGRHHTERLDNQ LRGRAGRQGDPGSSVFFSSWEDDLVMSHLEDNKLPLECDETGRVISPKAATLLEHAQRVAEGRLLDVHAN TWRYNQLIAQQRAILVERRNTLLRTTTARDEIAELVPERYEEVKARLTAKDSETGEAKLETICRLIMLYH LDRAWADHLAFLADIRESIHLRALGRQNPLDEFHRMAVDAFASLAADAIEAAQQTFETAPSIEDEPGVDL SKLARPTSTWTYMVHDNPLADDTLSALSLPGVFR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_3162 | - | - | 100% (805) | preprotein translocase subunit SecA |
M. vanbaalenii PYR-1 | Mvan_1598 | - | e-119 | 38.85% (677) | preprotein translocase, SecA subunit |
M. vanbaalenii PYR-1 | Mvan_1762 | - | e-111 | 37.50% (624) | preprotein translocase subunit SecA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1852 | secA2 | 0.0 | 82.21% (798) | preprotein translocase subunit SecA |
M. gilvum PYR-GCK | Mflv_3408 | - | 0.0 | 88.90% (802) | preprotein translocase subunit SecA |
M. tuberculosis H37Rv | Rv1821 | secA2 | 0.0 | 82.21% (798) | preprotein translocase subunit SecA |
M. leprae Br4923 | MLBr_02082 | secA2 | 0.0 | 81.15% (780) | preprotein translocase subunit SecA |
M. abscessus ATCC 19977 | MAB_2397 | - | 0.0 | 75.35% (775) | preprotein translocase subunit SecA |
M. marinum M | MMAR_2698 | secA2 | 0.0 | 82.42% (785) | preprotein translocase ATPase SecA2 |
M. avium 104 | MAV_2894 | - | 0.0 | 83.50% (782) | preprotein translocase subunit SecA |
M. smegmatis MC2 155 | MSMEG_3654 | - | 0.0 | 83.33% (786) | preprotein translocase subunit SecA |
M. thermoresistible (build 8) | TH_2328 | - | 0.0 | 83.29% (784) | ATPase SecA2 |
M. ulcerans Agy99 | MUL_3040 | secA2 | 0.0 | 82.55% (785) | preprotein translocase subunit SecA |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_3162|M.vanbaalenii_PYR-1 ------MSGAAPPSGPPRPSAKYRDRVARTSSKTDSPKTGRLSGRFWKLL Mflv_3408|M.gilvum_PYR-GCK ------MARTSSKTSSGPATSSEPAASPEPAAKTAKPKTGRLSGRFWKLL MSMEG_3654|M.smegmatis_MC2_155 ------------------------------MPKTSSAKPGRLSSKFWKLL TH_2328|M.thermoresistible__bu ------------------------------VAKTKTRTPGRVSNRFWKLL MMAR_2698|M.marinum_M --MRSCTAAPGVSRTNTHARRGLGVAYRWAVSKTTRAQSGHLSSRFWRLL MUL_3040|M.ulcerans_Agy99 --MRSCTAAPGVSRTNTHARRGLGVAYRWAVSKTTRAQSGRLSSRFWRLL MAV_2894|M.avium_104 ------------------------------MPKTNRAQPGRLSSRFWRLL Mb1852|M.bovis_AF2122/97 MNVHGCPRIAACRCTDTHPRGRPAFAYRWFVPKTTRAQPGRLSSRFWRLL Rv1821|M.tuberculosis_H37Rv MNVHGCPRIAACRCTDTHPRGRPAFAYRWFVPKTTRAQPGRLSSRFWRLL MLBr_02082|M.leprae_Br4923 ------------------------------MSKTPRTQPGRLSSRFWRLL MAB_2397|M.abscessus_ATCC_1997 ------------------------------MRKSNTAS--RFTGKFWKLL *: :.:.:**:** Mvan_3162|M.vanbaalenii_PYR-1 GASTDKDQARSMAQVHKAAEFDAKAADLDDEQLRKAARLLELDDLADSTD Mflv_3408|M.gilvum_PYR-GCK GASTDKDQSRSMDLVVKSADFDSKAADLDDEQLAKAAKLLVLDDLADSAD MSMEG_3654|M.smegmatis_MC2_155 GASTERNQARSLSEVKGAADFEKKAADLDDEQLTKAAKLLKLEDLAGASD TH_2328|M.thermoresistible__bu GASTDRELNRSMGQVRASEKFDEKAAALDADQLKKAVELLELEDLANAAD MMAR_2698|M.marinum_M GATTEKNQNRSLAQVTASADFDKEAADLNDEKLRKAAGLLNLEDLADSAD MUL_3040|M.ulcerans_Agy99 GATTEKNQNRSLAQVTASAEFDKEAADLNDEKLRKAAGLLNLEDLADSAD MAV_2894|M.avium_104 GASTEKNRSRSLTLVTDSSEYDDEAAGLTDEQLRKAAGLLNLEDLAESED Mb1852|M.bovis_AF2122/97 GASTEKNRSRSLADVTASAEYDKEAADLSDEKLRKAAGLLNLDDLAESAD Rv1821|M.tuberculosis_H37Rv GASTEKNRSRSLADVTASAEYDKEAADLSDEKLRKAAGLLNLDDLAESAD MLBr_02082|M.leprae_Br4923 GASTDKNLNYSSAEVTAAAAYHKEAADLGDEQLRKACGLLNLNDLADSRD MAB_2397|M.abscessus_ATCC_1997 GAATDKNQSQSLALVDASKKYDEKAKDLTDEQLTKAAKKLDLTEGLESKD **:*::: * * : :. :* * ::* ** * * : : * Mvan_3162|M.vanbaalenii_PYR-1 VPQFLAIAREAAKRTTGLTPFDVQLQGALRMLAGDVVEMATGEGKTLSGA Mflv_3408|M.gilvum_PYR-GCK VPQFLAIARAAAERATGLKPFDVQLQGALRMLAGDVVEMATGEGKTLSGA MSMEG_3654|M.smegmatis_MC2_155 ITQFLAIAREAAERTTGLRPFDVQLLAALRMLAGDVVEMATGEGKTLAGA TH_2328|M.thermoresistible__bu IPQFLAIARVAAERTSKMRPFDVQLLAALRMLAGDVVEMATGEGKTLAGA MMAR_2698|M.marinum_M IPQFLAIAREAGERATGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGA MUL_3040|M.ulcerans_Agy99 IPQFLAIAREAGERATGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGA MAV_2894|M.avium_104 IPQFLAIAREAAERATGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGA Mb1852|M.bovis_AF2122/97 IPQFLAIAREAAERRTGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGA Rv1821|M.tuberculosis_H37Rv IPQFLAIAREAAERRTGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGA MLBr_02082|M.leprae_Br4923 VPQFLAIVREASERSTGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGA MAB_2397|M.abscessus_ATCC_1997 IGQFLAIVREAAERTIDERPFDVQLLGALRMLDGDVIEMATGEGKTLTGA : *****.* *.:* ****** .***** ***:**********:** Mvan_3162|M.vanbaalenii_PYR-1 IAAAGYALAGRNVHVITINDYLARRDAEWMGPLIEAMGLTIGWITADSTA Mflv_3408|M.gilvum_PYR-GCK IAAAGYALAGRNVHVITINDYLARRDAEWMGPLIEAMGLTVGWITAESTA MSMEG_3654|M.smegmatis_MC2_155 IAAAGYALGGRRVHVITINDYLARRDAEWMGPLLKALGLTVGWITADSTA TH_2328|M.thermoresistible__bu IAAAGYAIAGRSVHVITINDYLARRDAEWMGSLLEAMGLTVGWITADSTA MMAR_2698|M.marinum_M IAAAGYALGGRHVHVVTINDYLARRDAEWMAPLLEAMDLTVGWITAESTG MUL_3040|M.ulcerans_Agy99 IAAAGYALGGRHVHVVTINDYLARRDAEWMAPLLEAMDLTVGWITAESTG MAV_2894|M.avium_104 IAAAGYALAGRHVHVVTINDYLARRDAEWMGPLIEAMGLTVGWITAESSS Mb1852|M.bovis_AF2122/97 IAAAGYALAGRHVHVVTINDYLARRDAEWMGPLLDAMGLTVGWITADSTP Rv1821|M.tuberculosis_H37Rv IAAAGYALAGRHVHVVTINDYLARRDAEWMGPLLDAMGLTVGWITADSTP MLBr_02082|M.leprae_Br4923 IAAAGYALAGRHVHVVTINDYLARRDAEWMGPLLEAIGLTVGWITAESTR MAB_2397|M.abscessus_ATCC_1997 ITAAGYALGGRSVHVISVNDYLARRDAEWMGPFLERMGLTVGWITEESTA *:*****:.** ***:::************..::. :.**:**** :*: Mvan_3162|M.vanbaalenii_PYR-1 AERRAAYRCDITYASVNEIGFDVLRDQLVTDVDDLVSPNPDVALIDEADS Mflv_3408|M.gilvum_PYR-GCK AERRAAYACDVTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADS MSMEG_3654|M.smegmatis_MC2_155 DERREAYQCDVTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADS TH_2328|M.thermoresistible__bu DERRAAYQCDITYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADS MMAR_2698|M.marinum_M ADRRAAYECDVTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADS MUL_3040|M.ulcerans_Agy99 ADRRAAYECDVTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADS MAV_2894|M.avium_104 EERRAAYGCDVTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADS Mb1852|M.bovis_AF2122/97 DERRTAYDRDVTYASVNEIGFDVLRDQLVTDVNDLVSPNPDVALIDEADS Rv1821|M.tuberculosis_H37Rv DERRTAYDRDVTYASVNEIGFDVLRDQLVTDVNDLVSPNPDVALIDEADS MLBr_02082|M.leprae_Br4923 EDRKAAYGCDVTYASVNEIGFDVLRDQLVTDVDDLVSPHPDVALIDEADS MAB_2397|M.abscessus_ATCC_1997 EERRKAYACDVTYGSVNEIGFDVLRDQLAIDVDDLVSPSPDVAVVDEADS :*: ** *:**.**************. ** ***** ****::***** Mvan_3162|M.vanbaalenii_PYR-1 VLVDEALVPLVLAGTSHRETPRLELIRLVGELDENTD----FATDNDSRN Mflv_3408|M.gilvum_PYR-GCK VLVDEALVPLVLAGTSHRETPRVELIRLVGELDENTD----FATDNDSRN MSMEG_3654|M.smegmatis_MC2_155 VLVDEALVPLVLAGTSHREQPRVEIIRMVGELEAGKH----YDTDAESRN TH_2328|M.thermoresistible__bu VLVDEALVPLVLAGTSHREQPRLEIVRLVGELTPGVD----YDTDADNRN MMAR_2698|M.marinum_M VLVDEALVPLVLAGTTHRETPRLEIIKLVGQLVKDKDADEYFATDADSRN MUL_3040|M.ulcerans_Agy99 VLVDEALVPLVLAGTTHRETPRLEIIKLVAQLVKDKDADEYFATDADSRN MAV_2894|M.avium_104 VLVDEALVPLVLAGTTHRETPRLEIIKLVGELEAGTD----YDTDADSRN Mb1852|M.bovis_AF2122/97 VLVDEALVPLVLAGTTHRETPRLEIIRLVAELVGDKDADEYFATDSDNRN Rv1821|M.tuberculosis_H37Rv VLVDEALVPLVLAGTTHRETPRLEIIRLVAELVGDKDADEYFATDSDNRN MLBr_02082|M.leprae_Br4923 VLVDEALVPLVLAGATHRETPRLEIIKLVGELSAESD----YDTDSDSRN MAB_2397|M.abscessus_ATCC_1997 VLVDEALVPLVLAGTSHREAPSSEVIEAVRELIAGED----YEADNDRRN **************::*** * *::. * :* . : :* : ** Mvan_3162|M.vanbaalenii_PYR-1 VHLTEAGARKIEAALGGIDLYSEEHVATTLTEVNVALHAHVLLQRDVHYI Mflv_3408|M.gilvum_PYR-GCK VHLTEAGARKVEAALGGIDLYSEEHVATTLTEINVALHAHVLLQRDVHYI MSMEG_3654|M.smegmatis_MC2_155 VHLTEAGARVMEAKLGGIDLYSEEHVGTTLTEINVALHAHVLLQRDVHYI TH_2328|M.thermoresistible__bu VHLTEAGAQKMEAALGGIDLYSEEHVATTLTEINVALHAHVLLQRDVHYI MMAR_2698|M.marinum_M VHLTEAGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYI MUL_3040|M.ulcerans_Agy99 VHLTEAGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYI MAV_2894|M.avium_104 VHLTDVGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYI Mb1852|M.bovis_AF2122/97 VHLTEHGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYI Rv1821|M.tuberculosis_H37Rv VHLTEHGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYI MLBr_02082|M.leprae_Br4923 VHLTDVGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYI MAB_2397|M.abscessus_ATCC_1997 IFLTDTGARKLEKQLGNIDLYSEHHVGTTLTEVNVALHAHVLLERDVHYI :.**: **: :* **.******.**.*****:**********:****** Mvan_3162|M.vanbaalenii_PYR-1 VRDDAVHLINSSRGRIATLQRWPDGLQAAVEAKEGIETTETGEVLDTITV Mflv_3408|M.gilvum_PYR-GCK VRDDAVHLINASRGRIATLQRWPDGLQAAVEAKEGIETTETGEVLDTITV MSMEG_3654|M.smegmatis_MC2_155 VRDDAVHLINASRGRIASLQRWPDGLQAAVEAKEGIETTETGEVLDTITV TH_2328|M.thermoresistible__bu VRDGAVHLINSSRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITV MMAR_2698|M.marinum_M VRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITV MUL_3040|M.ulcerans_Agy99 VRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITV MAV_2894|M.avium_104 VRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITV Mb1852|M.bovis_AF2122/97 VRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITV Rv1821|M.tuberculosis_H37Rv VRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITV MLBr_02082|M.leprae_Br4923 VRDDAVHLVNASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITV MAB_2397|M.abscessus_ATCC_1997 VRDGAVHLINSSRGRIAALQRWPDGLQAAVEAKEGIETTDTGEVLDTITV ***.****:*:****** *********************:********** Mvan_3162|M.vanbaalenii_PYR-1 QALINRYPRVCGMTGTALAAGEQLRQFYKLGVSPIPPNKPNIRQDETDRV Mflv_3408|M.gilvum_PYR-GCK QALINRYPRVCGMTGTALAAGEQLRQFYKLGVSPIPPNKPNIRKDETDRV MSMEG_3654|M.smegmatis_MC2_155 QALINRYPRVCGMTGTALAAGEQLRQFYKLGVSPIPPNTPNIRKDEPDRV TH_2328|M.thermoresistible__bu QALINRYPTVCGMTGTALAAGEQLRQFYKLGVSPIPPNKPNIRVDEEDRV MMAR_2698|M.marinum_M QALINRYVTVCGMTGTALAAGEQLRQFYKLGVSPIPPNTPNIREDESDRV MUL_3040|M.ulcerans_Agy99 QALINRYVTVCGMTGTALAAGEQLRQFYKLGVSPIPPNTPNIREDESDRV MAV_2894|M.avium_104 QALINRYATVCGMTGTALAAGEQLRQFYKLGVSPIPPNKPNIREDEADRV Mb1852|M.bovis_AF2122/97 QALINRYATVCGMTGTALAAGEQLRQFYQLGVSPIPPNKPNIREDEADRV Rv1821|M.tuberculosis_H37Rv QALINRYATVCGMTGTALAAGEQLRQFYQLGVSPIPPNKPNIREDEADRV MLBr_02082|M.leprae_Br4923 QALINRYATVCGMTGTALAAGEQLRQFYKLGVSPIPPNTPNIRDDASDRV MAB_2397|M.abscessus_ATCC_1997 QALINRYPRVSGMTGTALAAGEQLRQFYKLGVSPIPPNTPNIREDQPDRV ******* *.*****************:*********.**** * *** Mvan_3162|M.vanbaalenii_PYR-1 YVTIAAKNDAVIEHIAEVHETGQPVLVGTRDVAESEEIHRRLVKAGVPAV Mflv_3408|M.gilvum_PYR-GCK YVTISAKNAAILEHIAEVHKTGQPVLVGTRDVAESEEVHERLVKAGVPAV MSMEG_3654|M.smegmatis_MC2_155 YITAAAKIDAIVEHIAEVHKTGQPVLVGTHDVAESEELHEKLLKAGVPAV TH_2328|M.thermoresistible__bu YINTEAKNAAIVEHVAKVHATGQPVLVGTHDVAESEELHKKLVKAGVPAV MMAR_2698|M.marinum_M YITAAAKNDAIVEHIAEVHDTGQPVLVGTRDVAESEDLHERLLRRDIPAV MUL_3040|M.ulcerans_Agy99 YITAAAKNDAIVEHIAEVHDTGQPVLVGTRDVAESEDLHERLLRRDIPAV MAV_2894|M.avium_104 YITAAAKNDAIVEHIIEVHETGQPVLVGTRDVAESEELHERLLRRGVPAV Mb1852|M.bovis_AF2122/97 YITTAAKNDGIVEHITEVHQRGQPVLVGTRDVAESEELHERLVRRGVPAV Rv1821|M.tuberculosis_H37Rv YITTAAKNDGIVEHITEVHQRGQPVLVGTRDVAESEELHERLVRRGVPAV MLBr_02082|M.leprae_Br4923 YITAAAKNDAIVAHLAEVHETGQPVLVGTRNVAESEELHERLLRHGVPAV MAB_2397|M.abscessus_ATCC_1997 YITEASKNDAIVAHIAEIHATGQPVLVGTHDVAESEALHHRLVRAGVPAV *:. :* .:: *: ::* ********::***** :*.:*:: .:*** Mvan_3162|M.vanbaalenii_PYR-1 VLNAKNDAEEAAVIAEAGKLGAVTVSTQMAGRGTDIRLGGS----DEEDH Mflv_3408|M.gilvum_PYR-GCK VLNAKNDAEEAAVIAEAGKLGAVTVSTQMAGRGTDIRLGGS----DEASH MSMEG_3654|M.smegmatis_MC2_155 VLNAKNDAEEAAVIAEAGKLGAVTVSTQMAGRGTDIRLGGSDVGDDDAEK TH_2328|M.thermoresistible__bu VLNAKNDAEEAAVIAEAGKLGAVTVSTQMAGRGTDIRLGGSDAGDDSAAK MMAR_2698|M.marinum_M VLNAKNDAEEAAVIAEAGTLSRVTVSTQMAGRGTDIRLGGS----DEADH MUL_3040|M.ulcerans_Agy99 VLNAKNDAEEAAVIAEAGTLSRVTVSTQMAGRGTDIRLGGS----DEADH MAV_2894|M.avium_104 VLNAKNDAEEAQVIAEAGKFGVVTVSTQMAGRGTDIRLGGS----DEADH Mb1852|M.bovis_AF2122/97 VLNAKNDAEEARVIAEAGKYGAVTVSTQMAGRGTDIRLGGS----DEADH Rv1821|M.tuberculosis_H37Rv VLNAKNDAEEARVIAEAGKYGAVTVSTQMAGRGTDIRLGGS----DEADH MLBr_02082|M.leprae_Br4923 VLNAKNDAEEARFIAEAGKFGAVTVSTQMAGRGTDIRLGGS----DESDH MAB_2397|M.abscessus_ATCC_1997 VLNAKNDAEEARVIAEAGALKAVTVSTQMAGRGTDIRLGGS----DETDY *********** .***** ******************* *. Mvan_3162|M.vanbaalenii_PYR-1 DRVAELGGLHVIGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDLV Mflv_3408|M.gilvum_PYR-GCK DEVVELGGLHVIGTGRHNTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVV MSMEG_3654|M.smegmatis_MC2_155 KKVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVV TH_2328|M.thermoresistible__bu KEVAELGGLHVVGTGRHHTARLDNQLRGRAGRQGDPGSSVFFASWDDPVV MMAR_2698|M.marinum_M DQVAELGGLHVVGTGRHHTQRLDNQLRGRAGRQGDPGSSVFFSSWEDDVV MUL_3040|M.ulcerans_Agy99 DQVAELGGLHVVGTGRHHTQRLDNQLRGRAGRQGDPGSSVFFSSWEDDVV MAV_2894|M.avium_104 DRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVV Mb1852|M.bovis_AF2122/97 DRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVV Rv1821|M.tuberculosis_H37Rv DRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVV MLBr_02082|M.leprae_Br4923 DRVVELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVI MAB_2397|M.abscessus_ATCC_1997 DAVVEAGGLHVVGTGRHRTERLDNQLRGRAGRQGDPGSSVFFSSWEDEVV . *.* *****:*****.* **********************:**:* :: Mvan_3162|M.vanbaalenii_PYR-1 MSHLEDNKLPLECD---ETGRVISPKAATLLEHAQRVAEGRLLDVHANTW Mflv_3408|M.gilvum_PYR-GCK VAHLEDSKLPLDCD---EDGKILSPKAATLLEHAQRVAEGRLLDVHANTW MSMEG_3654|M.smegmatis_MC2_155 AAHLERSKLPMETDPDAGDGRIIAPRAASLLDHAQRVAEGRLLDVHANTW TH_2328|M.thermoresistible__bu ASHLEDNKLPLDTD---EDGRIVHPKATSLLDHAQRIAEGRLLDVHANTW MMAR_2698|M.marinum_M AANLDGNKLPMETD---EDGQIVSAKAAGLLDHAQRVAEGRMLDVHANTW MUL_3040|M.ulcerans_Agy99 AANLDGNKLPMETD---EDGQIVSAKAAGLLDHAQRVAEGRMLDVHANTW MAV_2894|M.avium_104 AANLDRNKLPMETDPETGDGRIVSPKAAGLLDHAQRVAEGRMLDVHANTW Mb1852|M.bovis_AF2122/97 AANLDHNKLPMATD---ENGRIVSPRTGSLLDHAQRVAEGRLLDVHANTW Rv1821|M.tuberculosis_H37Rv AANLDHNKLPMATD---ENGRIVSPRTGSLLDHAQRVAEGRLLDVHANTW MLBr_02082|M.leprae_Br4923 AANLDRNKLPMQTD---EDGRIISLKTTGLLDHAQRVAEGRLLDVHANTW MAB_2397|M.abscessus_ATCC_1997 VAHLDSAKLPTETD---ENGRIVSPKAGGLIDHAQRVAEGAMLDLHANTW ::*: *** * *::: :: *::****:*** :**:***** Mvan_3162|M.vanbaalenii_PYR-1 RYNQLIAQQRAILVERRNTLLRTTTARDEIAELVPERYEEVKARLTAKDS Mflv_3408|M.gilvum_PYR-GCK RYNQLIAQQRAILVERRDKLLRTATARDELAERSPERYAEVSERLEAKDP MSMEG_3654|M.smegmatis_MC2_155 RYNQLIAQQRAIIVERRETLLRTDTAREELKERSPERYAKLAEELGED-- TH_2328|M.thermoresistible__bu RYNQLIAQQRAIIVERRNTLLRTPTAREELAERSPERYAELTEELGPG-- MMAR_2698|M.marinum_M RYNQLIAQQRAIIVDRRNTLLRTATAREELADLAPKRYKELSETVS---- MUL_3040|M.ulcerans_Agy99 RYNQLIAQQRAIIVDRRNTLLRTATAREELADLAPKRYKELSETVS---- MAV_2894|M.avium_104 RYNQLIAQQRAIIVDRRNTLLRTATAREELAELAPKRYRELAEEIP---- Mb1852|M.bovis_AF2122/97 RYNQLIAQQRAIIVERRNTLLRTVTAREELAELAPKRYEELSDKVS---- Rv1821|M.tuberculosis_H37Rv RYNQLIAQQRAIIVERRNTLLRTVTAREELAELAPKRYEELSDKVS---- MLBr_02082|M.leprae_Br4923 RYNQLIAQQRAIIVDRRNALLSSATAREELAELAPKRYEELAQALPKEE- MAB_2397|M.abscessus_ATCC_1997 RYNQLIAQQRAIISDRRDTLLRTDTARKELQERSPERYDELAEELS---- ************: :**: ** : ***.*: : *:** :: : Mvan_3162|M.vanbaalenii_PYR-1 ETGEAKLETICRLIMLYHLDRAWADHLAFLADIRESIHLRALGRQNPLDE Mflv_3408|M.gilvum_PYR-GCK GTAEEKLVKICRLIMLYHLDRAWADHLAFLSDIRESIHLRALGRQNPLDE MSMEG_3654|M.smegmatis_MC2_155 --AEERLEKICRLIMLYHLDRGWCEHLAFLADIRESIHLRALGRQNPLDE TH_2328|M.thermoresistible__bu --AEEKLEKICRLIMLYHLDRGWADHLAFLADIRESIHLRALGRQNPLDE MMAR_2698|M.marinum_M ---EDRLEKICRMIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDE MUL_3040|M.ulcerans_Agy99 ---EHRLEKICRMIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDE MAV_2894|M.avium_104 ---EERLETICRHIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDE Mb1852|M.bovis_AF2122/97 ---EERLETICRQIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDE Rv1821|M.tuberculosis_H37Rv ---EERLETICRQIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDE MLBr_02082|M.leprae_Br4923 --AEERLETICRLIMLYHLDRGWADHLAYLADIRESIHLRALGRQSPLDE MAB_2397|M.abscessus_ATCC_1997 ---EEWLERISRQIMLYHLDRGWADHLAYLSDVRESIHLRALGRQNPIDE * * *.* ********.*.:***:*:*:************.*:** Mvan_3162|M.vanbaalenii_PYR-1 FHRMAVDAFASLAADAIEAAQQTFETAPSIEDEPGVDLSKLARPTSTWTY Mflv_3408|M.gilvum_PYR-GCK FHRMAVDAFGSLAADAIEAAQQTFDTAPAIEDETGVDLSKLARPTSTWTY MSMEG_3654|M.smegmatis_MC2_155 FHRMAVDAFASLAADAIEAAQQTFETAESVADEPGVDLSKLARPTSTWTY TH_2328|M.thermoresistible__bu FHRMAVDAFASLAADAIEAAQQTFETAESIEDEPGVDLSKLARPTSTWTY MMAR_2698|M.marinum_M FHRMAVDAFASLAADAIEAAQQTFETANVLEDEPGLDLSKLARPTSTWTY MUL_3040|M.ulcerans_Agy99 FHRMAVDAFASLAADAIEAAQQTFETANVLEDEPGLDLSKLARPTSTWTY MAV_2894|M.avium_104 FHRLAVDAFASLAADAIEAAQQTFETANVLEDEPGLDLSKLARPTSTWTY Mb1852|M.bovis_AF2122/97 FHRMAVDAFASLAADAIEAAQQTFETANVLDHEPGLDLSKLARPTSTWTY Rv1821|M.tuberculosis_H37Rv FHRMAVDAFASLAADAIEAAQQTFETANVLDHEPGLDLSKLARPTSTWTY MLBr_02082|M.leprae_Br4923 FHRLAVNAFALLAADAIEAAQQTFETANILDGAPGLDLSKLARPTSTWTY MAB_2397|M.abscessus_ATCC_1997 FHRLAVDAFASLAADAVEAAQQTFETANLVDEEQGLDLSKLARPTSTWTY ***:**:**. *****:*******:** : *:************** Mvan_3162|M.vanbaalenii_PYR-1 MVHDNPLADDTLSALSLPGVFR Mflv_3408|M.gilvum_PYR-GCK MVHDNPL-DDTLSALSLPGVFR MSMEG_3654|M.smegmatis_MC2_155 MVHDNPLADDTMSALSLPGVFR TH_2328|M.thermoresistible__bu MVHDNPLEDETTSALSLPGVFR MMAR_2698|M.marinum_M MVNDNPLSDDTLSTLSLPGVFR MUL_3040|M.ulcerans_Agy99 MVNDNPLSDDTLSTLSLPGVFR MAV_2894|M.avium_104 MVNDNPLSDDTLSTLSLPGVFR Mb1852|M.bovis_AF2122/97 MVNDNPLSDDTLSALSLPGVFR Rv1821|M.tuberculosis_H37Rv MVNDNPLSDDTLSALSLPGVFR MLBr_02082|M.leprae_Br4923 MVNDAPLSDDTLSPLSLPGVFR MAB_2397|M.abscessus_ATCC_1997 MIHDDPRKNDSLSILNLPGVFS *::* * ::: * *.*****