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MGRVLRWTTAGESHGRALVAMVEGMVAGVHVTTQDISAQLARRRLGYGRGARMKFEQDQVTMLTGLRHGV TLGGPIAIEIGNTEWPKWETVMAPDPVDPAVLADSAARNAPLTRPRPGHADYAGMLKYGFDDARPVLERA SARETAARVAAGTVARAFLQQALGVEIVSHVISIGASKPYDGPPPQAADLTAIDASPVRAFDAASEALMI DEIEAAKRDGDTLGGVVEVVAHGLPVGLGSFTSGDNRLDSQLAGAVMGIQAIKGVEIGDGFETARRRGSV AHDEIYPGADGVMRSTNRAGGLEGGMTNGLPVRVRAAMKPISTVPRALATVDMATGEEAVAIHQRSDVCA VPAAAVVVETMVALVLARAVLEKFGGDSLAETRANIDSYLRAVATREPSTDGARASG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2645 | - | - | 100% (407) | chorismate synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2569c | aroF | 0.0 | 85.15% (404) | chorismate synthase |
| M. gilvum PYR-GCK | Mflv_3758 | - | 0.0 | 92.98% (399) | chorismate synthase |
| M. tuberculosis H37Rv | Rv2540c | aroF | 0.0 | 85.15% (404) | chorismate synthase |
| M. leprae Br4923 | MLBr_00516 | aroF | 0.0 | 82.74% (394) | chorismate synthase |
| M. abscessus ATCC 19977 | MAB_2843c | - | 0.0 | 81.25% (400) | chorismate synthase |
| M. marinum M | MMAR_2175 | aroF | 0.0 | 83.91% (404) | chorismate synthase AroF |
| M. avium 104 | MAV_3417 | aroC | 0.0 | 85.03% (394) | chorismate synthase |
| M. smegmatis MC2 155 | MSMEG_3030 | aroC | 0.0 | 88.00% (400) | chorismate synthase |
| M. thermoresistible (build 8) | TH_0110 | aroF | 0.0 | 84.62% (390) | PROBABLE CHORISMATE SYNTHASE AROF |
| M. ulcerans Agy99 | MUL_1759 | aroF | 0.0 | 83.66% (404) | chorismate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2569c|M.bovis_AF2122/97 ---MLRWITAGESHGRALVAVVEGMVAGVHVTSADIADQLARRRLGYGRG
Rv2540c|M.tuberculosis_H37Rv ---MLRWITAGESHGRALVAVVEGMVAGVHVTSADIADQLARRRLGYGRG
MMAR_2175|M.marinum_M ---MLRWITAGESHGRALVALVDGMVAGVEVTSTEIADQLARRRLGYGRG
MUL_1759|M.ulcerans_Agy99 ---MLRWITAGESHGRALVALVDGMVAGVEVTSTEIADQLARRRLGYGRG
MLBr_00516|M.leprae_Br4923 ---MLRWITAGESHGRALVAVVEGMVAGVEVTSTAIADQLARRRLGYGRG
MAV_3417|M.avium_104 ---MLRWITAGESHGRALVAVLEGMVAGVEITSTDISEQLARRRLGYGRG
Mvan_2645|M.vanbaalenii_PYR-1 MGRVLRWTTAGESHGRALVAMVEGMVAGVHVTTQDISAQLARRRLGYGRG
Mflv_3758|M.gilvum_PYR-GCK ----MRWTTAGESHGRALVAMVEGMVAGVEVTSGDVAGQLARRRLGYGRG
TH_0110|M.thermoresistible__bu ------------------VAVLEGMVAGVPVTSADIAEQLRRRRLGYGRG
MSMEG_3030|M.smegmatis_MC2_155 ---MLRWTTAGESHGRALVAMLEGMVAGVPITSEEIGAQLKRRRLGYGRG
MAB_2843c|M.abscessus_ATCC_199 ---MLRWITAGESHGRALVAVLEGMVAGVELTSEDIGRQLARRRLGYGRG
**:::****** :*: :. ** *********
Mb2569c|M.bovis_AF2122/97 ARMTFERDAVTVLSGIRHGSTLGGPIAIEIGNTEWPKWETVMAADPVDP-
Rv2540c|M.tuberculosis_H37Rv ARMTFERDAVTVLSGIRHGSTLGGPIAIEIGNTEWPKWETVMAADPVDP-
MMAR_2175|M.marinum_M ARMAFERDAVTVLSGLRHGSTLGGPIAIEIGNTEWPKWEAVMAADPLDPA
MUL_1759|M.ulcerans_Agy99 ARMAFERDAVTVLSGIRHGSTLGGPIAIEIGNTEWPKWEAVMAADPLDPA
MLBr_00516|M.leprae_Br4923 ARMAFERDGVTVLSGVRHGVTLGGPIAIEIDNTEWPKWESVMAADPVDA-
MAV_3417|M.avium_104 ARMSFERDAVSVLSGVRHGLTLGGPIAVEIGNTEWPKWETVMATDPVDP-
Mvan_2645|M.vanbaalenii_PYR-1 ARMKFEQDQVTMLTGLRHGVTLGGPIAIEIGNTEWPKWETVMAPDPVDP-
Mflv_3758|M.gilvum_PYR-GCK ARMKFEQDQVTMLTGLRHGVTLGGPIAIEIGNTEWPKWETVMAPDPVDP-
TH_0110|M.thermoresistible__bu ARMKFEQDEVTMLAGVRHGVTLGGPIAIQIGNTEWPKWETVMAPDPVDP-
MSMEG_3030|M.smegmatis_MC2_155 ARMKFEQDQVTMLAGVRHGLTLGGPIAIEIGNTEWPKWESVMSPDPVDP-
MAB_2843c|M.abscessus_ATCC_199 ARMAFEADQVTMLGGVRHGLTLGGPVAIEVGNTEWPKWETVMSPDPVDP-
*** ** * *::* *:*** *****:*:::.********:**:.**:*.
Mb2569c|M.bovis_AF2122/97 --AELAD-VARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAA
Rv2540c|M.tuberculosis_H37Rv --AELAD-VARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAA
MMAR_2175|M.marinum_M AAAELEN-SARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAA
MUL_1759|M.ulcerans_Agy99 AAAELEN-SARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAA
MLBr_00516|M.leprae_Br4923 --AELED-SARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAA
MAV_3417|M.avium_104 --AQLAD-SARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAA
Mvan_2645|M.vanbaalenii_PYR-1 --AVLADSAARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAA
Mflv_3758|M.gilvum_PYR-GCK --ESLADSAARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAA
TH_0110|M.thermoresistible__bu --AELAD-VARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAA
MSMEG_3030|M.smegmatis_MC2_155 --ADLDV--ARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAA
MAB_2843c|M.abscessus_ATCC_199 --AELQN-IARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAA
* *****************************************
Mb2569c|M.bovis_AF2122/97 RVAAGTVARAFLRQALGVEVLSHVISIGASAPYEGPPPRAEDLPAIDASP
Rv2540c|M.tuberculosis_H37Rv RVAAGTVARAFLRQALGVEVLSHVISIGASAPYEGPPPRAEDLPAIDASP
MMAR_2175|M.marinum_M RVAAGTVARAFLRQALGVEVLSHVVSIGASAPYDGPPPQPEDLPAIDASP
MUL_1759|M.ulcerans_Agy99 RVAAGTVARAFLRQALGVEVLSHVVSIGASAPYDGPPPQPEDLLAIDASP
MLBr_00516|M.leprae_Br4923 RVAAGTIARQFLRQALGVEVLSHVISIGASARYDGPPPGSEDLTVIDASL
MAV_3417|M.avium_104 RVAAGTIARSFLRQALGVEVLSHVIAIGPSAPYEGPPPGPGDLPAIDASP
Mvan_2645|M.vanbaalenii_PYR-1 RVAAGTVARAFLQQALGVEIVSHVISIGASKPYDGPPPQAADLTAIDASP
Mflv_3758|M.gilvum_PYR-GCK RVAAGTVARAFLRQALGVEIVSHVISIGASKPYDGPPPSAADLAAIDDSP
TH_0110|M.thermoresistible__bu RVAAGTVARNFLREALGVEVISHIISIGASTPYDGPPPQPSDLAAIDESP
MSMEG_3030|M.smegmatis_MC2_155 RVAAGTVARAFLREALGVEVLSHVISIGASKPYDGPAPQFSDLSAIDDSP
MAB_2843c|M.abscessus_ATCC_199 RVAVGTLAKAFLKQALGVDVISHVISIGDSDPYEGPVPDAADLAAIDASP
***.**:*: **::****:::**:::** * *:** * ** .** *
Mb2569c|M.bovis_AF2122/97 VRAYDKAAEADMIAQIEAAKKDGDTLGGVVEAVALGLPVGLGSFTSGDHR
Rv2540c|M.tuberculosis_H37Rv VRAYDKAAEADMIAQIEAAKKDGDTLGGVVEAVALGLPVGLGSFTSGDHR
MMAR_2175|M.marinum_M VRAFDGQAEKSMIAEIEAAKKDGDTLGGVVEVVALGLPVGLGSFTSGENR
MUL_1759|M.ulcerans_Agy99 VRAFDGQAEKSMIAEIEAAKKDGDTLGGVVEVVALGLPVGLGSFTSGENR
MLBr_00516|M.leprae_Br4923 VRAFDEQVEKSMIAEIEAAKKDGDTLGGVVEAVVLGLPVGLGSFTSGDDR
MAV_3417|M.avium_104 VRAYDEAAEQAMIAEIEAAKKDGDTLGGVVEVVALGLPVGLGSFTSGDNR
Mvan_2645|M.vanbaalenii_PYR-1 VRAFDAASEALMIDEIEAAKRDGDTLGGVVEVVAHGLPVGLGSFTSGDNR
Mflv_3758|M.gilvum_PYR-GCK VRAFDSDSEALMIAEIEAAKRDGDTLGGVVEVVAHGLPVGLGSFTSGDDR
TH_0110|M.thermoresistible__bu VRAFGKDAEESMIAEIESAKRDGDTLGGVIEVVATGLPVGLGSFTSGDDR
MSMEG_3030|M.smegmatis_MC2_155 VRAFDKASEELMIAEIEAAKRDGDTLGGVVEVVADGLPVGLGSFTSGENR
MAB_2843c|M.abscessus_ATCC_199 VRAFDAQAESSMISEIEAAKKDGDTLGGVVEVVVAGLPVGLGSFISGQDR
***:. * ** :**:**:********:*.*. ********* **:.*
Mb2569c|M.bovis_AF2122/97 LDSQLAAAVMGIQAIKGVEIGDGFQTARRRGSRAHDEMYPGPDGVVRSTN
Rv2540c|M.tuberculosis_H37Rv LDSQLAAAVMGIQAIKGVEIGDGFQTARRRGSRAHDEMYPGPDGVVRSTN
MMAR_2175|M.marinum_M LDSQLAAAVMGIQAIKGVEIGDGFETARRRGSRAHDEMYPGTDGVVRSTN
MUL_1759|M.ulcerans_Agy99 LDSQLAAAVMGIQAIKGVEIGDGFETARRRGSRAHDEMYPGTDGVVRSTN
MLBr_00516|M.leprae_Br4923 LDSQLAAAVMGIQAIKGVEIGDGFATARRRGSCAHDEMYSGPGGVVRLTN
MAV_3417|M.avium_104 LDGQLAAAVMGIQAIKGVEIGDGFATARRRGSQAHDEMYPGPDGVVRSTN
Mvan_2645|M.vanbaalenii_PYR-1 LDSQLAGAVMGIQAIKGVEIGDGFETARRRGSVAHDEIYPGADGVMRSTN
Mflv_3758|M.gilvum_PYR-GCK LDSQLAGAVMGIQAIKGVEIGDGFETARRRGSVAHDEIYPGPDGVMRSTN
TH_0110|M.thermoresistible__bu LDSQLAGAVMGIQAMKGVEIGDGFETARRRGSQAHDEMYPGPDGVSRSTN
MSMEG_3030|M.smegmatis_MC2_155 LDSQLAAAVMGIQAIKGVEIGDGFETARRRGSVAHDEMYPGPDGVVRSTN
MAB_2843c|M.abscessus_ATCC_199 LDSQLAAAIMGIQAIKGVEIGDGFTTARRRGSAAHDEIYPGPDGILRSTN
**.***.*:*****:********* ******* ****:*.*..*: * **
Mb2569c|M.bovis_AF2122/97 RAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDLATGDEAVAIHQRSD
Rv2540c|M.tuberculosis_H37Rv RAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDLATGDEAVAIHQRSD
MMAR_2175|M.marinum_M RAGGLEGGMTNGQPLRVRAAMKPISTVPKALATVDLATGDEAVAIHQRSD
MUL_1759|M.ulcerans_Agy99 RAGGLEGGMTNGQPLRVRAAMKPISTVPKALATVDLATGDEAVAIHQRSD
MLBr_00516|M.leprae_Br4923 RSGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDLATGEEAIAIHQRSD
MAV_3417|M.avium_104 RAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDMATGDEAVAIHQRSD
Mvan_2645|M.vanbaalenii_PYR-1 RAGGLEGGMTNGLPVRVRAAMKPISTVPRALATVDMATGEEAVAIHQRSD
Mflv_3758|M.gilvum_PYR-GCK RAGGLEGGMTNGLPVRVRAAMKPISTVPRALATIDMTTGEEAVAIHQRSD
TH_0110|M.thermoresistible__bu RAGGLEGGMTNGQPLRVRAAMKPISTVPRALSTVDMTTGEQASAIHQRSD
MSMEG_3030|M.smegmatis_MC2_155 RAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDMTSGEEAVAIHQRSD
MAB_2843c|M.abscessus_ATCC_199 RAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDMSTGDEAVAIHQRSD
*:********** *:*************:**:*:*:::*::* *******
Mb2569c|M.bovis_AF2122/97 VCAVPAAGVVVETMVALVLARAALEKFGGDSLAETQRNIAAYQRSVADRE
Rv2540c|M.tuberculosis_H37Rv VCAVPAAGVVVETMVALVLARAALEKFGGDSLAETQRNIAAYQRSVADRE
MMAR_2175|M.marinum_M VCAVPAAAVVVETMVALVLARVTLEKFGGDSLAETRRNIEAYQRSVADRE
MUL_1759|M.ulcerans_Agy99 VCAVPAAAVVVETMVALVLARVTLEKFGGDSLAETRRNIEAYQRSVADRE
MLBr_00516|M.leprae_Br4923 VCAVPAAGVVVETMVALVLARAALRKFGGDSLGETRRNLAAYQRAVADRE
MAV_3417|M.avium_104 VCAVPAAGVVVEAMVALVLARAALQKFGGDSLAETRRNIDAYRRAVAERE
Mvan_2645|M.vanbaalenii_PYR-1 VCAVPAAAVVVETMVALVLARAVLEKFGGDSLAETRANIDSYLRAVATRE
Mflv_3758|M.gilvum_PYR-GCK VCAVPAAGVVVETMVALVLARAALAKFGGDSLGETRANIDGYLRAVSARE
TH_0110|M.thermoresistible__bu VCAVPAAGVVVETMVALVLARAALKKFGGDSLTETRTNIDNYLRAVAARE
MSMEG_3030|M.smegmatis_MC2_155 VCAVPAAGVVVETMVALVLARAALEKFGGDSLAETRANIDSYLRAVAERE
MAB_2843c|M.abscessus_ATCC_199 VCAVPAAGVVAEAMVALVVARAALEKFGGDSLSETKTNVAAYLDAVAQRE
*******.**.*:*****:**..* ******* **: *: * :*: **
Mb2569c|M.bovis_AF2122/97 A--------PAARVSG------
Rv2540c|M.tuberculosis_H37Rv A--------PAARVSG------
MMAR_2175|M.marinum_M A--------PAARARAIRG---
MUL_1759|M.ulcerans_Agy99 A--------PAARARAIRG---
MLBr_00516|M.leprae_Br4923 A--------PVAQYCGESGIGG
MAV_3417|M.avium_104 A--------PAARGTA------
Mvan_2645|M.vanbaalenii_PYR-1 P--------STD-GARASG---
Mflv_3758|M.gilvum_PYR-GCK P--------SAN-GAPT-----
TH_0110|M.thermoresistible__bu P--------SARPAAQASG---
MSMEG_3030|M.smegmatis_MC2_155 P--------AAQASS-------
MAB_2843c|M.abscessus_ATCC_199 PRQESSDEQPARRAANTAG---
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