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VSTFWRYVKIQLFVLLCGIVGPIFLVIYFATGADPMMRWMFWTGLLVTAIDVLIALVMTNVGARSAAKTQ ALEASGVLALAQVVGIHETNTRINDRPLVKLDLQVSGPGITPFSTQDQVIASVSRLPMITSRKLVALVDP VTNDYQIDWERSALVSGMMPATFSVAEDNTTYDLTGQTEALMEILQVLKANGIGMDSMIDLRANPAARQQ VQAIVRHAAARQPVPPPVPAAAPYAAPPVEPTTAQRLQELETLRATGSITDDEYAAKRQQIIADL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1285 | - | - | 100% (275) | hypothetical protein Mvan_1285 |
| M. vanbaalenii PYR-1 | Mvan_2994 | - | 1e-16 | 58.33% (60) | hypothetical protein Mvan_2994 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0705 | - | 2e-90 | 60.89% (271) | hypothetical protein Mb0705 |
| M. gilvum PYR-GCK | Mflv_5073 | - | 1e-131 | 83.27% (275) | hypothetical protein Mflv_5073 |
| M. tuberculosis H37Rv | Rv0686 | - | 4e-91 | 60.89% (271) | hypothetical protein Rv0686 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3845c | - | 3e-58 | 43.33% (270) | hypothetical protein MAB_3845c |
| M. marinum M | MMAR_1015 | - | 6e-89 | 60.15% (271) | hypothetical protein MMAR_1015 |
| M. avium 104 | MAV_4487 | - | 1e-84 | 55.36% (280) | hypothetical protein MAV_4487 |
| M. smegmatis MC2 155 | MSMEG_1406 | - | 1e-112 | 71.53% (281) | hypothetical protein MSMEG_1406 |
| M. thermoresistible (build 8) | TH_1888 | - | 4e-93 | 61.01% (277) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0767 | - | 2e-85 | 58.30% (271) | hypothetical protein MUL_0767 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0705|M.bovis_AF2122/97 --MLARYIKMQLLVLLCGGLVGPIFLVVYFTLGLGSLMSWMFYVGLIITV
Rv0686|M.tuberculosis_H37Rv --MLARYIKMQLLVLLCGGLVGPIFLVVYFTLGLGSLMSWMFYVGLIITV
MMAR_1015|M.marinum_M --MLARYLKMQLLVLLCGGLVGPIFLIVYFALGVGSLLSWMLYVGLLITV
MUL_0767|M.ulcerans_Agy99 --MLARYLKMQLLVLLCGGLVGPIFLIVYFALDVGSLLSWMLYVGLLITV
MAV_4487|M.avium_104 --MLARYLKAQLVVLLCGGLVGPIFLVVYFTLGLGSLLQWMFYVGLLITV
Mvan_1285|M.vanbaalenii_PYR-1 MSTFWRYVKIQLFVLLCG-IVGPIFLVIYFATGADPMMRWMFWTGLLVTA
Mflv_5073|M.gilvum_PYR-GCK MSTFWRYVKIQAFVLLCG-IVGPIFLVIYFATGADPLLAWMFWTGLLITA
MSMEG_1406|M.smegmatis_MC2_155 -MRRARYLRIQAFVLLCG-IVGPIFLVIYFGSGGSPLIKWMFWTGLLITA
TH_1888|M.thermoresistible__bu MSTFWRYLRIQAFILLCG-IVGPLFLAIYFMTGADPTLKWMFWAGLGVTA
MAB_3845c|M.abscessus_ATCC_199 MNVVARFLKILAFSLLCG-IVGPIFIVMYYVID-EPATSWMLYSGIGITI
*::: . **** :***:*: :*: . . **:: *: :*
Mb0705|M.bovis_AF2122/97 ADVLVALALTNYGAKTAAKTAALERSGVLALAQSTGLSETGTRINDQPLV
Rv0686|M.tuberculosis_H37Rv ADVLVALALTNYGAKTAAKTAALERSGVLALAQITGLSETGTRINDQPLV
MMAR_1015|M.marinum_M ADVLIALALTNFGAKSAAKSAELEQSGVLALAQITGLTETGTRINDRPLV
MUL_0767|M.ulcerans_Agy99 ADVLIALALTSFDAKSAAKSAELEQSGVLALAQITGLTETGTRINDRPLV
MAV_4487|M.avium_104 ADVLIALALANYGAKSSEKLAALEQNGVLALAQITGITETGTWVNNQQVV
Mvan_1285|M.vanbaalenii_PYR-1 IDVLIALVMTNVGARSAAKTQALEASGVLALAQVVGIHETNTRINDRPLV
Mflv_5073|M.gilvum_PYR-GCK ADVLIALAITGFGARSAAKKQALEATGVLALGQIVGIHETNTRINDQPLV
MSMEG_1406|M.smegmatis_MC2_155 LDVLIALAITAMGTRSAAKHQDLEQNGVIALAQVVGIHETNTRINERPLV
TH_1888|M.thermoresistible__bu TDVLIALALTSFGTRSAAKKAALERDGVVALARVTHIGRTNTHINNQPLV
MAB_3845c|M.abscessus_ATCC_199 GIVVLAFVLTLLFTKNEEARKLLEANGILALADVMAANETGMTVNDQPVI
*::*:.:: ::. ** *::**. .*. :*:: ::
Mb0705|M.bovis_AF2122/97 KVHLHISGPGITPFDTEDRVIASVTRLGNLTARKLVVLVNPATQQYLIDW
Rv0686|M.tuberculosis_H37Rv KVHLHISGPGITPFDTEDRVIASVTRLGNLTARKLVVLVNPATQQYLIDW
MMAR_1015|M.marinum_M KVHLHISGPGIAAFDSEDRVIASVTRLGNLTARKLVVLVNPTTQEYLIDW
MUL_0767|M.ulcerans_Agy99 KVHLHISGSGIAAFDSEDRVIASVTRLGNLTARKLVVLVNPATREYLIDW
MAV_4487|M.avium_104 KVHLHIAGPGLVPFDSEDRVIASVTRLGNLNARKVVVLLNPTTNEYRIDW
Mvan_1285|M.vanbaalenii_PYR-1 KLDLQVSGPGITPFSTQDQVIASVSRLPMITSRKLVALVDPVTNDYQIDW
Mflv_5073|M.gilvum_PYR-GCK KIDLQVSGPGITPFSTQDQVVASVSRLPMITNRQLAMLVDPITNDYQIDW
MSMEG_1406|M.smegmatis_MC2_155 KLDLQISGPGIAPFASQDRVLASVARLPMITNRKLVAVVDPTTHEYRIDW
TH_1888|M.thermoresistible__bu KLDLQISGPGIATFTSRDRVLASPDRMPMLNRGQLVALVDPTTREYQIDW
MAB_3845c|M.abscessus_ATCC_199 KLTLQVHGDGISPFRAETRARVSVLQVPTLSRGKLVVLVAPGTEQFQIDW
*: *:: * *: .* :. :. .* :: :. ::. :: * *.:: ***
Mb0705|M.bovis_AF2122/97 ERSALVNGLVPAQFTVAEDNKTYDLSGQTGPLMEILQILKANNVPLNRMV
Rv0686|M.tuberculosis_H37Rv ERSALVNGLVPAQFTVAEDNKTYDLSGQTGPLMEILQILKANNVPLNRMV
MMAR_1015|M.marinum_M ERSALVNGLVPAQFTVAEDNRTYDLSGQAGPLMEILQILKANGIPLNRMV
MUL_0767|M.ulcerans_Agy99 ERSALVNGLVPAQFTVAEDNRTYDLSGQAGPLMEILQILKANGIPLNRMV
MAV_4487|M.avium_104 ERSALVNGLVPAQFTVAEDNTTYDLSGQAGPLMEIMQILKANNIPLNRMV
Mvan_1285|M.vanbaalenii_PYR-1 ERSALVSGMMPATFSVAEDNTTYDLTGQTEALMEILQVLKANGIGMDSMI
Mflv_5073|M.gilvum_PYR-GCK ERSALVSGMMPATFTISEDNQTYDLTGQTEPLMEILQVLKSHGIGVDHMI
MSMEG_1406|M.smegmatis_MC2_155 DRSSLVSGLMPATFTIAEDNTTYDLTGQTEPLLEILQILKAHNIGMNNMI
TH_1888|M.thermoresistible__bu QRSALIGGPVPATVTLDSDGSTHDLSGQVEPLLEILRILKAHGIAPDGPI
MAB_3845c|M.abscessus_ATCC_199 QRSALLNGQVPAKFTSSSQGREYDLTGQAGPLFEIMKVLKANGIGSDGVI
:**:*:.* :** .: .:. :**:**. .*:**:::**::.: : :
Mb0705|M.bovis_AF2122/97 DIRSNPALRQQVQAVVRRAAERQAPA---AEP---------------ASQ
Rv0686|M.tuberculosis_H37Rv DIRSNPALRQQVQAVVRRAAERQAPA---AEP---------------ASQ
MMAR_1015|M.marinum_M DIRSNPVLRQQIQAVVRRAAQQQMPAGA-AQPS-------------AAPQ
MUL_0767|M.ulcerans_Agy99 DIRSNPVLRQQIQAVVRRAAQQQMPAGA-AQPS-------------ATPQ
MAV_4487|M.avium_104 DIRSNPALRAQIQAVVRRAAQQQAPAGQ-PAPAGQPATGQPSAPVAAPPG
Mvan_1285|M.vanbaalenii_PYR-1 DLRANPAARQQVQAIVRHAAARQPVPP--PVPAAAPYAAPPVEP------
Mflv_5073|M.gilvum_PYR-GCK DLRSNPAARQQVQAIVRRAVAQQAPPP--PVPAGAPYLAAAPEP------
MSMEG_1406|M.smegmatis_MC2_155 DLRANPVAREQVQRVVRRAAAQRNAPQGVPQPAGQPTPQPAAAAPYAAPS
TH_1888|M.thermoresistible__bu DLRDQPAARQQVQAVIRRPVAGAAQAT----PAPTPAASAP---------
MAB_3845c|M.abscessus_ATCC_199 DIRSNPVARQQIDAILRKTEAGERSMGAETGNGG----------------
*:* :*. * *:: ::*:.
Mb0705|M.bovis_AF2122/97 GSIAERLAELESLRASGAVNAAEYESKRAQIISEI
Rv0686|M.tuberculosis_H37Rv GSIAERLAELESLRASGAVNAAEYESKRAQIISEI
MMAR_1015|M.marinum_M ASIAERLQELESLHASGALNAQEYASRRAQIISEI
MUL_0767|M.ulcerans_Agy99 ASIAERLQELESLHASGALNAQEYASRRAQIISEI
MAV_4487|M.avium_104 PSIAARLQELNDLHASGALTEQEYNSRRAAIIAEI
Mvan_1285|M.vanbaalenii_PYR-1 -TTAQRLQELETLRATGSITDDEYAAKRQQIIADL
Mflv_5073|M.gilvum_PYR-GCK -TTAQRLQELETLRATGSITDDEYAAKRAEIIAEL
MSMEG_1406|M.smegmatis_MC2_155 MSTAQRLQELETLRATGAISEAEYTAKRQQIIADL
TH_1888|M.thermoresistible__bu -SIGQRLQELESLRADGMITESEYQAKRRQIIAEL
MAB_3845c|M.abscessus_ATCC_199 -SVADRLAELDRLKLASLISEAEYGDKRTEILRDL
: . ** **: *: . :. ** :* *: ::