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GRYTRSLNAIAYRGGVAAQLDPTKALATILIEHGPLPKDAIAHRLREMGVADPEDLLPRLLNEIDCPAVP LVDESWVWLPALLAGRIFTHRVTAQELAHDVLLVTPDLDAITHLCEFEPYARLVDGSPVSVALPAFDEDV LDERGVPPEMVDDGGALVLPPGTLRGLGVVDGDLVGLRLAPEGLTLAQVTADPSPAVGAALAATLNPDEP VSFDSAVWTACVAHSALFTEPTPPLSEIAADHGLEARGDLLAPAGFDFDRWRFELDCEVLKRRYDLDDDD ALAVRALKAIYEQMSQLITMLPADEDFADDADEDAAAEDAPVPPLDGYQELVAEMGAELADPRLAEVLVA ETLGRDPDGAAALGLFAETLEPQVPRRARVAFRWLRAVALERMGDIESAERELLAAESMDTDWPLPLYDL ARIASDRGDVERGLALLRRAGADPDDPLLEMLSSFRGEARPDVGRNEPCWCGSGRKYKKCHLGKEQPALP ERVGWLYSKAAQHALMSGWRALIVELDYERNQFHDAPDETADPLVVDAALFEGGAFEDFLAVRGPLLPED ERSLAEQWLLVDRSLFEVGQVRPGHGVTVRDVRTGDIHEVQERTASRHLKSGQLICTRVLPAGDDTAQFF GGLEPVALHQRDALIALLDEGPDPVDLVAFLSLRFAPPTLTNTEGDPMIICEATVHVGDAASIQSALDDT YDRVEDAEPPKWFEHVTTHGMERIRATLALDGETLRVETNSEERMDRVLATVARLDPAMQVLEDTREYVD DPRAMAARMPETAKGAIEPDDPEIAALLDAMILDYEAKWLDEPIPALDGHTPRQAADDPTRRPDLIRLLD SFPADAGRHGMSVDRLRAALGLP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1143 | - | - | 100% (864) | SecC motif-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0630c | - | 0.0 | 62.35% (858) | hypothetical protein Mb0630c |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0613c | - | 0.0 | 62.35% (858) | hypothetical protein Rv0613c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1285 | - | 0.0 | 53.14% (845) | TPR repeat-containing protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0630c|M.bovis_AF2122/97 ----------------MAEAFDATQAVARILAEHGPLSEDDIARRLLDSG
Rv0613c|M.tuberculosis_H37Rv ----------------MAEAFDATQAVARILAEHGPLSEDDIARRLLDSG
Mvan_1143|M.vanbaalenii_PYR-1 MGRYTRSLNAIAYRGGVAAQLDPTKALATILIEHGPLPKDAIAHRLREMG
MSMEG_1285|M.smegmatis_MC2_155 -------------------MATVTDAVARILAEQGPLHTDEIERLLQASG
*.*:* ** *:*** * * : * *
Mb0630c|M.bovis_AF2122/97 VADPDAVLRALRLETEWPARQLVDDRWVWLPTLLAGRVFTHRLGADEAVH
Rv0613c|M.tuberculosis_H37Rv VADPDAVLRALRLETEWPARQLVDDRWVWLPTLLAGRVFTHRLGADEAVH
Mvan_1143|M.vanbaalenii_PYR-1 VADPEDLLPRLLNEIDCPAVPLVDESWVWLPALLAGRIFTHRVTAQELAH
MSMEG_1285|M.smegmatis_MC2_155 EPVPEPVV----DELSMPVGMLVDDRWVWLPTVLDGRVFTHRLSAHEVAH
. *: :: * . *. ***: *****::* **:****: *.* .*
Mb0630c|M.bovis_AF2122/97 DMLGVTPDLDPITTLCEHEEYGRLADGSAARIVLAGYDEELLERRGIPDE
Rv0613c|M.tuberculosis_H37Rv DMLGVTPDLDPITTLCEHEEYGRLADGSAARIVLAGYDEELLERRGIPDE
Mvan_1143|M.vanbaalenii_PYR-1 DVLLVTPDLDAITHLCEFEPYARLVDGSPVSVALPAFDEDVLDERGVPPE
MSMEG_1285|M.smegmatis_MC2_155 DMLDAAVDLDPVSDLFHLDEYLRLADGSPVSFAVADYDDELLEDRGIPLE
*:* .: ***.:: * . : * **.***.. ..:. :*:::*: **:* *
Mb0630c|M.bovis_AF2122/97 AIDPGGALLLEPGTLATLGAAAGDLVGVRLTAAGLVLERIGTAGADTSVG
Rv0613c|M.tuberculosis_H37Rv AIDPGGALLLEPGTLATLGAAAGDLVGVRLTAAGLVLERIGTAGADTSVG
Mvan_1143|M.vanbaalenii_PYR-1 MVDDGGALVLPPGTLRGLGVVDGDLVGLRLAPEGLTLAQV-TADPSPAVG
MSMEG_1285|M.smegmatis_MC2_155 LAGESGVVLLAPGTLAALKAAEGDLVGLRLTDQGLALETIETVVD-ADIG
. .*.::* **** * .. *****:**: **.* : *. . :*
Mb0630c|M.bovis_AF2122/97 ARLAELVDPDEPAFFPAAVWTACVDDPAAFTEPVAPLREILDQHGLTHED
Rv0613c|M.tuberculosis_H37Rv ARLAELVDPDEPAFFPAAVWTACVDDPAAFTEPVAPLREILDQHGLTHED
Mvan_1143|M.vanbaalenii_PYR-1 AALAATLNPDEPVSFDSAVWTACVAHSALFTEPTPPLSEIAADHGLEARG
MSMEG_1285|M.smegmatis_MC2_155 NRLAEVLPGDEPTFVDAAALTLCAEDPTVFVEATAPLSEVIREAGLAYSD
** : ***. . :*. * *. ..: *.*...** *: : ** .
Mb0630c|M.bovis_AF2122/97 DWLAPGGFNFDAWRFENRCELLAFRHDLDPNDAVALYTLIKLHETMSLLL
Rv0613c|M.tuberculosis_H37Rv DWLAPGGFNFDAWRFENRCELLAFRHDLDPNDAVALYTLIKLHETMSLLL
Mvan_1143|M.vanbaalenii_PYR-1 DLLAPAGFDFDRWRFELDCEVLKRRYDLDDDDALAVRALKAIYEQMSQLI
MSMEG_1285|M.smegmatis_MC2_155 GFIAPAGFDFGRWRFETACHRSADTHGLDPDDAVALQTLIMALEQLT---
. :**.**:*. **** *. :.** :**:*: :* * ::
Mb0630c|M.bovis_AF2122/97 EATDPDE--LPRDVLATAAETATETGSDSLVDLLGDIGAALADPLLAELL
Rv0613c|M.tuberculosis_H37Rv EATDPDE--LPRDVLATAAETATETGSDSLVDLLGDIGAALADPLLAELL
Mvan_1143|M.vanbaalenii_PYR-1 TMLPADEDFADDADEDAAAEDAPVPPLDGYQELVAEMGAELADPRLAEVL
MSMEG_1285|M.smegmatis_MC2_155 --VDADS-----------------------LPLLRRAGAALENPVVADAL
.*. *: ** * :* :*: *
Mb0630c|M.bovis_AF2122/97 VAETVGTDSGGAAALGLLTEMLEPKVPRAARVAVRWLRAVALDRIGDVEA
Rv0613c|M.tuberculosis_H37Rv VAETVGTDSGGAAALGLLTEMLEPKVPRAARVAVRWLRAVALDRIGDVEA
Mvan_1143|M.vanbaalenii_PYR-1 VAETLGRDPDGAAALGLFAETLEPQVPRRARVAFRWLRAVALERMGDIES
MSMEG_1285|M.smegmatis_MC2_155 VEETVDAGRGSPESLSRLTEALEAQVPRPARAAVRWLRATALERAGDIAA
* **:. . ... :*. ::* **.:*** **.*.*****.**:* **: :
Mb0630c|M.bovis_AF2122/97 AERELLAAESMDTEWPLPLLDLARIASDRGDAERGLALLRRAGTEPDHPL
Rv0613c|M.tuberculosis_H37Rv AERELLAAESMDTEWPLPLLDLARIASDRGDAERGLALLRRAGTEPDHPL
Mvan_1143|M.vanbaalenii_PYR-1 AERELLAAESMDTDWPLPLYDLARIASDRGDVERGLALLRRAGADPDDPL
MSMEG_1285|M.smegmatis_MC2_155 AERELLAAETMDTEWPLTLVDLAHIASDRGDAERALALLRRAGFPPDHPN
*********:***:***.* ***:*******.**.******** **.*
Mb0630c|M.bovis_AF2122/97 VRLLERHRAQPRRDLGRNEACWCGSGRKYKKCHLGREALPLAERVDWLYA
Rv0613c|M.tuberculosis_H37Rv VRLLERHRAQPRRDLGRNEACWCGSGRKYKKCHLGREALPLAERVDWLYA
Mvan_1143|M.vanbaalenii_PYR-1 LEMLSSFRGEARPDVGRNEPCWCGSGRKYKKCHLGKEQPALPERVGWLYS
MSMEG_1285|M.smegmatis_MC2_155 VQFLQRYLVAPRPDLGRNEPCWCGSGRKYKKCHLGNEQLSLEERAAWLYS
:.:*. . .* *:****.***************.* .* **. ***:
Mb0630c|M.bovis_AF2122/97 KASQHALSGDWTGLLAEVSYERFRYADSDDEDALAAALADPLVLDAVLFE
Rv0613c|M.tuberculosis_H37Rv KASQHALSGDWTGLLAEVSYERFRYADSDDEDALAAALADPLVLDAVLFE
Mvan_1143|M.vanbaalenii_PYR-1 KAAQHALMSGWRALIVELDYERNQFHDAPDET------ADPLVVDAALFE
MSMEG_1285|M.smegmatis_MC2_155 KAAQHVSETHWHGMLLELALERSRYAD-DLHDAIAEAMSDPLVMDALLHE
**:**. * .:: *: ** :: * . :****:** *.*
Mb0630c|M.bovis_AF2122/97 GGAFAEFLEVRGSLLPDDERLLAEQWLLVERSVFEVEHVQPGEGVIVRDV
Rv0613c|M.tuberculosis_H37Rv GGAFAEFLEVRGSLLPDDERLLAEQWLLVERSVFEVEHVQPGEGVIVRDV
Mvan_1143|M.vanbaalenii_PYR-1 GGAFEDFLAVRGPLLPEDERSLAEQWLLVDRSLFEVGQVRPGHGVTVRDV
MSMEG_1285|M.smegmatis_MC2_155 GDAFADFLRVRGPLLPDDERALAEQWLLVDRSVFEVQAVRPGETVTVRDV
*.** :** ***.***:*** ********:**:*** *:**. * ****
Mb0630c|M.bovis_AF2122/97 RTGDTHEVHERAASRQLRAGQLICARPVPAG-DTMVFFGGIEPVALHERA
Rv0613c|M.tuberculosis_H37Rv RTGDTHEVHERAASRQLRAGQLICARPVPAG-DTMVFFGGIEPVALHERA
Mvan_1143|M.vanbaalenii_PYR-1 RTGDIHEVQERTASRHLKSGQLICTRVLPAGDDTAQFFGGLEPVALHQRD
MSMEG_1285|M.smegmatis_MC2_155 RTGDRHEVRERLASREVKPGELLCARVLPTG-SIMQFFGGIERVSLGERD
**** ***:** ***.::.*:*:*:* :*:* . ****:* *:* :*
Mb0630c|M.bovis_AF2122/97 VLIELLDDEPDPVTLVAQLSRRFAPPTLVNTEGDSLAICEASVRVDDPAG
Rv0613c|M.tuberculosis_H37Rv VLIELLDDEPDPVTLVAQLSRRFAPPTLVNTEGDSLAICEASVRVDDPAG
Mvan_1143|M.vanbaalenii_PYR-1 ALIALLDEGPDPVDLVAFLSLRFAPPTLTNTEGDPMIICEATVHVGDAAS
MSMEG_1285|M.smegmatis_MC2_155 ELIELLDSRPDEVTLVAALTRRFAPPTLTNTEGDLLMVCEAAVRFADPA-
** ***. ** * *** *: *******.***** : :***:*:. *.*
Mb0630c|M.bovis_AF2122/97 IQGALDGVYDRVDGEEPPRWIEHVTNDGMLRVRATLVLDGDTLRVETNSE
Rv0613c|M.tuberculosis_H37Rv IQGALDGVYDRVDGEEPPRWIEHVTNDGMLRVRATLVLDGDTLRVETNSE
Mvan_1143|M.vanbaalenii_PYR-1 IQSALDDTYDRVEDAEPPKWFEHVTTHGMERIRATLALDGETLRVETNSE
MSMEG_1285|M.smegmatis_MC2_155 ---ALDAVYVRADD-DPPHWFEHVP--GKPQIRASLKLDGDTLRVETNSE
*** .* *.:. :**:*:***. * ::**:* ***:*********
Mb0630c|M.bovis_AF2122/97 PRMDRVLATLTRLDPAMTVLDDDRRPLRNTREAAALAEQMPVTGAGAPDP
Rv0613c|M.tuberculosis_H37Rv PRMDRVLATLTRLDPAMTVLDDDRRPLRNTREAAALAEQMPVTGAGAPDP
Mvan_1143|M.vanbaalenii_PYR-1 ERMDRVLATVARLDPAMQVLEDTR---EYVDDPRAMAARMPETAKGAIEP
MSMEG_1285|M.smegmatis_MC2_155 ERMDRVLAELGRLDPAMTVLEESR---------RPISEVTPPSRE-LLEP
******* : ****** **:: * .:: * : :*
Mb0630c|M.bovis_AF2122/97 DSPELAAALEEFIRDYETSWLDQPIPALDGHTPRQAADDPTRRADLIKLL
Rv0613c|M.tuberculosis_H37Rv DSPELAAALEEFIRDYETSWLDQPIPALDGHTPRQAADDPTRRADLIKLL
Mvan_1143|M.vanbaalenii_PYR-1 DDPEIAALLDAMILDYEAKWLDEPIPALDGHTPRQAADDPTRRPDLIRLL
MSMEG_1285|M.smegmatis_MC2_155 DDPEMIAAMEEFMRDYETRWLDESIPALNGLTPRQAADDPTRRGDLIKLL
*.**: * :: :: ***: ***:.****:* ************ ***:**
Mb0630c|M.bovis_AF2122/97 DTFPAGAGARGGMDADRLRTALGL-
Rv0613c|M.tuberculosis_H37Rv DTFPAGAGARGGMDADRLRTALGL-
Mvan_1143|M.vanbaalenii_PYR-1 DSFPADAGRHG-MSVDRLRAALGLP
MSMEG_1285|M.smegmatis_MC2_155 DSFPATE--RG-MNADRLRAALGLD
*:*** :* *..****:****