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GTHLNRARARFGTDTRGLLEGGRHALLHTRTLEFDELRPYVPGDDVRDIDWKASARSGSVLIKRFVSEKH HKILLVADSGRNMRGLAPDGERKCAVALNVLGALGLITLGRADEIGMVYGDARGSLRARQRRGENHIESM LAGYHTHTATPGPSDIVHQLTYVATHYRHPLLIVVVSDEPDPDDRLGDALDRLTARHDVMWAMIADMPAV EAGRGGYDVLSGRPVLGPAAVDPRVVAAYRSAEDRRTQHLAEFMAGHGISHATIAGSDEIRRRITAMTRV WSRAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0878 | - | - | 100% (286) | hypothetical protein Mvan_0878 |
| M. vanbaalenii PYR-1 | Mvan_5456 | - | 2e-13 | 26.85% (257) | hypothetical protein Mvan_5456 |
| M. vanbaalenii PYR-1 | Mvan_2750 | - | 2e-10 | 26.57% (207) | hypothetical protein Mvan_2750 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3718 | - | 6e-13 | 27.20% (250) | hypothetical protein Mb3718 |
| M. gilvum PYR-GCK | Mflv_0040 | - | 1e-127 | 76.92% (286) | hypothetical protein Mflv_0040 |
| M. tuberculosis H37Rv | Rv3693 | - | 6e-13 | 27.20% (250) | hypothetical protein Rv3693 |
| M. leprae Br4923 | MLBr_01809 | - | 8e-10 | 26.02% (196) | hypothetical protein MLBr_01809 |
| M. abscessus ATCC 19977 | MAB_0654 | - | 2e-64 | 49.27% (274) | hypothetical protein MAB_0654 |
| M. marinum M | MMAR_5203 | - | 9e-13 | 26.51% (249) | hypothetical protein MMAR_5203 |
| M. avium 104 | MAV_0411 | - | 4e-12 | 25.00% (208) | lipoprotein |
| M. smegmatis MC2 155 | MSMEG_6610 | - | 3e-96 | 62.50% (288) | protein of unknown function DUF58, putative |
| M. thermoresistible (build 8) | TH_1053 | - | 1e-98 | 61.25% (289) | protein of unknown function DUF58, putative |
| M. ulcerans Agy99 | MUL_4276 | - | 6e-13 | 26.51% (249) | hypothetical protein MUL_4276 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3718|M.bovis_AF2122/97 MILTGRTGLLALICVLPIALSPWPARAFVMLLVALAVAVTVDTLLAASTR
Rv3693|M.tuberculosis_H37Rv MILTGRTGLLALICVLPIALSPWPARAFVMLLVALAVAVTVDTLLAASTR
MMAR_5203|M.marinum_M MILTGRTGLMALIGVLPIALSPWPPRAFGMLLLALAVAVAIDVALAASPR
MUL_4276|M.ulcerans_Agy99 MILTGRTGLMALIGVLPIALSPWPPRAFGMLLLALAVAVAIDVALAASPR
MAV_0411|M.avium_104 MILTGRTGLVALICVLPIALSPWPAMVFTALLAALAVAVAVDAALAASPA
Mvan_0878|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0040|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6610|M.smegmatis_MC2_155 --------------------------------------------------
TH_1053|M.thermoresistible__bu --------------------------------------------------
MAB_0654|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01809|M.leprae_Br4923 --------------------------------------------------
Mb3718|M.bovis_AF2122/97 KLRFTRSPYTSARLGQPVDASLLLCNGGRRRFRGQVRDAWPPSARAQPHT
Rv3693|M.tuberculosis_H37Rv KLRFTRSPYTSARLGQPVDASLLLCNGGRRRFRGQVRDAWPPSARAQPHT
MMAR_5203|M.marinum_M KLSYTRGANSSIRLGQPADAALVIHNVGRRRFRGLVRDAWPPSARAQPRT
MUL_4276|M.ulcerans_Agy99 KLSYTRGANSSIRLGQPADAALVIHNVGRRRFRGLVRDAWPPSARAQPRT
MAV_0411|M.avium_104 RLRCIRSPDRSARLGQHADAALLIHNDGPRRFRGQIRDAWPPSARARPRL
Mvan_0878|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0040|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6610|M.smegmatis_MC2_155 --------------------------------------------------
TH_1053|M.thermoresistible__bu --------------------------------------------------
MAB_0654|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01809|M.leprae_Br4923 --------------------------------------------MIDPNP
Mb3718|M.bovis_AF2122/97 HDVDVAAGQRQQVHTALRPVRRGDQRAAMVTARSIGPLGLAGRQSSQSVP
Rv3693|M.tuberculosis_H37Rv HDVDVAAGQRQQVHTALRPVRRGDQRAAMVTARSIGPLGLAGRQSSQSVP
MMAR_5203|M.marinum_M HPINIAAGERQQVNTALQPVRRGDQHCAAVTARSIGPLGLAGRQRSQVVP
MUL_4276|M.ulcerans_Agy99 HPINIAAGERQQVNTALQPVRRGDQHCAAVTARSIGPLGLAGRQRSQVVP
MAV_0411|M.avium_104 HRVDIPAGQHQHIATRLEPVRRGDQRATVVTARSIGPLGLAGRQGSQSVP
Mvan_0878|M.vanbaalenii_PYR-1 ------------MGTHLNRARARFGTD---------TRGLLE--------
Mflv_0040|M.gilvum_PYR-GCK ------------MGTHLNRARAHFGTD---------TRGMLE--------
MSMEG_6610|M.smegmatis_MC2_155 ------------MGRHLDAAKAHFGRD---------AGGLLE--------
TH_1053|M.thermoresistible__bu ------------VGKYLDAAKRHFGTD---------VRGLLE--------
MAB_0654|M.abscessus_ATCC_1997 ------------MGVLLQQVKAETLTNNRLTGPTGLSRGLLE--------
MLBr_01809|M.leprae_Br4923 AAKPGVFHPPSMQRGQIDDPKLSAALRTLELTVKRKLDGVLH--------
: : *:
Mb3718|M.bovis_AF2122/97 GLVRVLPPFLSRKHLPSRLAKLREIDGLLPTLIRGQGTEFDSLREYVVGD
Rv3693|M.tuberculosis_H37Rv GLVRVLPPFLSRKHLPSRLAKLREIDGLLPTLIRGQGTEFDSLREYVVGD
MMAR_5203|M.marinum_M GQVRVLPPFLSRKHLPSRLAKLREIDGLLPTLIRGQGTEFDSLREYVVGD
MUL_4276|M.ulcerans_Agy99 GQVRVLPPFLSRKHLPSRLAKLREIDGLLPTLIRGQGTEFDSLREYVVGD
MAV_0411|M.avium_104 GQLRVLPPFLSRKHLPSRLARLREIDGLLPTLVRGQGTEFDSLREYVVGD
Mvan_0878|M.vanbaalenii_PYR-1 --------------------------GGRHALLHTRTLEFDELRPYVPGD
Mflv_0040|M.gilvum_PYR-GCK --------------------------GGRHALLHTRSLEFDELRPYVPGD
MSMEG_6610|M.smegmatis_MC2_155 --------------------------GGRYSLVHTRSLEFDELRPYVRGD
TH_1053|M.thermoresistible__bu --------------------------GGRYALLHTRSMEFDDLRPYVPGD
MAB_0654|M.abscessus_ATCC_1997 --------------------------GEHRSMFHGRSLEFDDLRPYILGD
MLBr_01809|M.leprae_Br4923 --------------------------GDHLGLISGPGSEPGESRVYQPGD
* :. * .. * * **
Mb3718|M.bovis_AF2122/97 DVRSIDWRASARRADVMVRTWRPERDRRVVIVLDTGRMAAGRVGVDPTAA
Rv3693|M.tuberculosis_H37Rv DVRSIDWRASARRADVMVRTWRPERDRRVVIVLDTGRMAAGRVGVDPTAA
MMAR_5203|M.marinum_M DVRSIDWRASARRADVMVRTWRPERDRRVVLVLDTGRMAAGRVGVDPTDA
MUL_4276|M.ulcerans_Agy99 DVRSIDWRASARRADVMVRTWRPERDRRVVLVLDTGRMAAGRVGVDPTDA
MAV_0411|M.avium_104 DVRSIDWRATARRADVVVRTWRPERDRRVVIVLDTGRTAAGRVGVDPTAA
Mvan_0878|M.vanbaalenii_PYR-1 DVRDIDWKASARSGSVLIKRFVSEKHHKILLVADSGRNMR--------GL
Mflv_0040|M.gilvum_PYR-GCK DVRDIDWKASARSGSVLIKRFVSEKHHKVLLVADTGRNMA--------AL
MSMEG_6610|M.smegmatis_MC2_155 DVRDIDWKATARSGHTLIKRFVSEKHHKILVVADGGRNMS--------AM
TH_1053|M.thermoresistible__bu DVRDIDWKASARSGDILIKRFVSEQHHKVLIVADAGRNMT--------AS
MAB_0654|M.abscessus_ATCC_1997 DVRDIDWRASARSSSVLVKRFVSYRQQRILAVADIGRNML--------AL
MLBr_01809|M.leprae_Br4923 DVRRMDWAVTARTTHPHVRQMIADRELETWMVIDMSASLD---------F
*** :** .:** :: . :. . * * .
Mb3718|M.bovis_AF2122/97 DPAGWPRLDWSMDAALLLAALASRAGDHVDFLAHDRISRAGVFGASRSEL
Rv3693|M.tuberculosis_H37Rv DPAGWPRLDWSMDAALLLAALASRAGDHVDFLAHDRISRAGVFGASRSEL
MMAR_5203|M.marinum_M DPAGWPRLDWSMDAALLLAALASRAGDHVDFLAHDRVSRAAVFGASRTEL
MUL_4276|M.ulcerans_Agy99 DPAGWPRLDWSMDAALLLAALASRAGDHVDFLAHDRVSRAAVFGASRTEL
MAV_0411|M.avium_104 DPAGWPRLDWSMDAALLLAALASRAGDHVDFLAHDRVGRAGVFGASRTEL
Mvan_0878|M.vanbaalenii_PYR-1 APDGERKCAVALNVLGALGLITLGRADEIGMVYGDARGSLRARQRRGENH
Mflv_0040|M.gilvum_PYR-GCK AADGERKSDVALHVLGAVGLITLGRSDQIGMVYGDARGSLRVRQSRGENH
MSMEG_6610|M.smegmatis_MC2_155 APSTELKRDVALNLIGAIGLITLPRSDEIGMVAGDRRGCVDIRLRRGETH
TH_1053|M.thermoresistible__bu APSGERKHDVALHIMGALGLITMRRSDQVGMVYGDVRGCVNIRAGRGECH
MAB_0654|M.abscessus_ATCC_1997 AASGEPKQRVAVNAVGVVGLIANSKGDEMGLVYGDEHASGRMPNRRGEPH
MLBr_01809|M.leprae_Br4923 GTTICEKRDLAVAAAAAITFLNSGGGNRLGALICNGARMTRVPARSGRQH
. : :: : : .:.:. : :
Mb3718|M.bovis_AF2122/97 LAQLVDAMAP--LRPALIESDWHAMIATILRRTRRRSLVVLLTDLNATAL
Rv3693|M.tuberculosis_H37Rv LAQLVDAMAP--LRPALIESDWHAMIATILRRTRRRSLVVLLTDLNATAL
MMAR_5203|M.marinum_M LAQLVDAMAP--LQPALVESDWRSMVATIARRTRRRSLVVLLTDLNATAL
MUL_4276|M.ulcerans_Agy99 LAQLVDAMAP--LQPALVESDWRSMVATIARRTRRRSLVVLLTDLNATAL
MAV_0411|M.avium_104 LAQLVDAMAP--LQPTLVETDWRAMVSAIALRARRRSLVVLLTDLNAAAL
Mvan_0878|M.vanbaalenii_PYR-1 IESMLAGYHTH-TAT-PGPSDIVHQLTYVATHYRHPLLIVVVSDE--PDP
Mflv_0040|M.gilvum_PYR-GCK IESMLAGYHDH-AGR-HGPSDIVCQLTYVATHYRHPMLIVVVSDE--PDT
MSMEG_6610|M.smegmatis_MC2_155 IESMLHRFHHH-TTTEPGPSDVATQLEWVARHHRHRLLVFVVSDE--PEI
TH_1053|M.thermoresistible__bu LESMLHRYHEQ-VCGRPGRSDVICQLDYAATHYRHQMLLVVVSDE--PEP
MAB_0654|M.abscessus_ATCC_1997 LEHMLERINSR-DITASGRSSIAAQLRYVERNYRHRHIVFVVSDE--PDL
MLBr_01809|M.leprae_Br4923 EQTLLRTIATTPKAPVGVRGDLTVAIDALRRPERRRGMAVIISDFLGPIN
:: . : *: : .:::* .
Mb3718|M.bovis_AF2122/97 DEGLLPVLPQLSARHHVLVAAVADPRVDQLAAGRSDAAAVYDAAAAERAR
Rv3693|M.tuberculosis_H37Rv DEGLLPVLPQLSARHHVLVAAVADPRVDQLAAGRSDAAAVYDAAAAERAR
MMAR_5203|M.marinum_M DEGLLPVLPQLSAKHQVVVAAVADPRVDQLAIGRSDAAAVYDAAAAERAR
MUL_4276|M.ulcerans_Agy99 DEGLLPVLPQLSAKHQVVVAAVADPRVDQLAIGRSDAAAVYDAAAAERAR
MAV_0411|M.avium_104 DEGLLPVLPQLSAKHHLLVAAVADPRVDQMAAGRSDAAAVYDAAAAERSR
Mvan_0878|M.vanbaalenii_PYR-1 DDRLGDALDRLTARHDVMWAMIADMPAVEAGR---GGYDVLSGRPVLGPA
Mflv_0040|M.gilvum_PYR-GCK DSRLEDAVARLTSRHDVMWAMVTDMPAAGVKD---GAYDVATGRPVLGSA
MSMEG_6610|M.smegmatis_MC2_155 TDRLDAVLRPLTARHDVLWPMIADMPALGTGE--QRGYEVSDGRLIAD--
TH_1053|M.thermoresistible__bu TQRLATTLSRLTARHDLMWAMVADRPAVGSGAAAQDGYDVGTGDVVLNGA
MAB_0654|M.abscessus_ATCC_1997 SDELDGEFRRLAARHSVYWITIKDAPLVGVPELGGEGYDVDSGRSILREE
MLBr_01809|M.leprae_Br4923 ---WMRPLRAIAARHEVLGIEVLDPRDVALPDIGEVVLQDAETG-VTREF
. ::::* : : *
Mb3718|M.bovis_AF2122/97 NDRRAIASQLRRGG----------VDVIDAPPAEIAPGLADRYLAMKATG
Rv3693|M.tuberculosis_H37Rv NDRRAIASQLRRGG----------VDVIDAPPAEIAPGLADRYLAMKATG
MMAR_5203|M.marinum_M NDRGTIAARLRRSG----------VEVVDAPPTEIAPALADRYLAMKATG
MUL_4276|M.ulcerans_Agy99 NDRGTIAARLRRSG----------VEVVDAPPTEIAPALADRYLAMKATG
MAV_0411|M.avium_104 NERAAIAARLRHGG----------VEVVDAAPAELAPALADHYLAMKATG
Mvan_0878|M.vanbaalenii_PYR-1 AVDPRVVAAYRSAEDRRTQHLAEFMAGHGISHATIAGSDEIRRRITAMTR
Mflv_0040|M.gilvum_PYR-GCK ATDPRVVAAYERAELRRAERLSQLLVARGVPRATITGSGQIRRAVGEMTR
MSMEG_6610|M.smegmatis_MC2_155 DLGADVLQAYRRAEEQRRQRLSEFLTGHRIPHTRVTGSARIRTALTAMTG
TH_1053|M.thermoresistible__bu VLGARVIDAYRRAEQARVRRLDEFMTTCGVPYTVIGGSSEIRRNLVALTE
MAB_0654|M.abscessus_ATCC_1997 ILGGGVIEAYQRAEAQREAAFDEYVNSSAIRCARVAGSRDLVKAITTMLK
MLBr_01809|M.leprae_Br4923 TIDAALRDDFARAAAAHCADVSRSLRNCGAPLMSLRTDRDWIADIVRFVE
: . : :
Mb3718|M.bovis_AF2122/97 RL---------
Rv3693|M.tuberculosis_H37Rv RL---------
MMAR_5203|M.marinum_M RL---------
MUL_4276|M.ulcerans_Agy99 RL---------
MAV_0411|M.avium_104 RL---------
Mvan_0878|M.vanbaalenii_PYR-1 VWSRAG-----
Mflv_0040|M.gilvum_PYR-GCK AWSRAG-----
MSMEG_6610|M.smegmatis_MC2_155 VYARAG-----
TH_1053|M.thermoresistible__bu RLARAR-----
MAB_0654|M.abscessus_ATCC_1997 RASRAT-----
MLBr_01809|M.leprae_Br4923 SRRRGALAGRQ