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TDPWARPPQQPGPPPAPFPQDQPPGYGPGPTSPTPQEGSSLPAKLKNIFSDPISIVLVVVIVLALVFAGL LGAELYARNRADTVVAGTVECVVQDDATASFGVLPPFLMQHVSGHYTNIRIETAGNQVRDAKGMKVDLDI NDVRLEDSPTSSGTIGSLVAHITWSAEGIKQTIQGAIPLVGSFVTGVTTNPNDGTVELEGALGSITARPE VADGGIALRVQQVTGLGFTLPREAVQPALDAFTSELTQDYPMDIRADSVEVTDSGVVSQFSTRNASIPKQ TDDPCFAGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0812 | - | - | 100% (290) | hypothetical protein Mvan_0812 |
| M. vanbaalenii PYR-1 | Mvan_1923 | - | 7e-72 | 48.76% (283) | hypothetical protein Mvan_1923 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0489c | - | 2e-74 | 57.14% (238) | hypothetical protein Mb0489c |
| M. gilvum PYR-GCK | Mflv_0096 | - | 1e-134 | 80.69% (290) | hypothetical protein Mflv_0096 |
| M. tuberculosis H37Rv | Rv0479c | - | 2e-74 | 57.14% (238) | hypothetical protein Rv0479c |
| M. leprae Br4923 | MLBr_02450 | - | 6e-74 | 53.88% (245) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4077 | - | 4e-49 | 39.13% (299) | hypothetical protein MAB_4077 |
| M. marinum M | MMAR_0804 | - | 1e-75 | 46.32% (326) | hypothetical protein MMAR_0804 |
| M. avium 104 | MAV_4671 | - | 2e-84 | 53.31% (302) | hypothetical protein MAV_4671 |
| M. smegmatis MC2 155 | MSMEG_0923 | - | 1e-102 | 59.29% (312) | hypothetical protein MSMEG_0923 |
| M. thermoresistible (build 8) | TH_2752 | - | 4e-98 | 67.04% (270) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4547 | - | 1e-73 | 49.48% (291) | hypothetical protein MUL_4547 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0489c|M.bovis_AF2122/97 MTNPQGPPND-PSPWARPGDQGPLARPPASSEASTGRLRPGEPAGHIQEP
Rv0479c|M.tuberculosis_H37Rv MTNPQGPPND-PSPWARPGDQGPLARPPASSEASTGRLRPGEPAGHIQEP
MMAR_0804|M.marinum_M MTNPQGPPNEGPSTWSRPSNQGPLGRPPSPVDPSGGPFRSGEPANPQQEP
MUL_4547|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02450|M.leprae_Br4923 --------------------------------------------------
MAV_4671|M.avium_104 MTNPQGPPKQDPSTWGRPANQGPYGQPPTERPTERINTGGPGQAPGQVPP
Mvan_0812|M.vanbaalenii_PYR-1 MTDP----------WAR---------------------------------
Mflv_0096|M.gilvum_PYR-GCK MTDP----------WAR---------------------------------
MSMEG_0923|M.smegmatis_MC2_155 MTDP----------WARPTDQAPQASSPQP--------------------
TH_2752|M.thermoresistible__bu --------------------------------------------------
MAB_4077|M.abscessus_ATCC_1997 MTTP-----------PQPPPGPSGSTPPEP--------------------
Mb0489c|M.bovis_AF2122/97 VSPPTQPEQQPQTEHLAASHAHTRRS-GRQAAHQAWDPTGLLAAQEE-EP
Rv0479c|M.tuberculosis_H37Rv VSPPTQPEQQPQTEHLAASHAHTRRS-GRQAAHQAWDPTGLLAAQEE-EP
MMAR_0804|M.marinum_M PTMAGIGPQQ--TEPIAASNADSRRPESTSPPASSASKTTSVATPEE-EP
MUL_4547|M.ulcerans_Agy99 --MAGIGPQQ--TEPIAASNADSRRPESTSPPASSASKTTSVATPEE-EP
MLBr_02450|M.leprae_Br4923 --------------------------------------------------
MAV_4671|M.avium_104 PPPAPAPPPPGQTERFGTPRPQMQQPGYPPPPTPPAGPTERLATAPNPDN
Mvan_0812|M.vanbaalenii_PYR-1 ------PPQ--QPGPPPAPFPQDQPPGYGPGPTSPTPQE---------GS
Mflv_0096|M.gilvum_PYR-GCK ------PPQ--QPGTAPGPFPQDPSQ-----PSAPAPQD---------DS
MSMEG_0923|M.smegmatis_MC2_155 --QPGLPPQDPQPTPPGAPPHAGAPGQPVQPGAPAEPPK---------GS
TH_2752|M.thermoresistible__bu ---MGGPP----PGQMGGPPPAGSEEQ---------------------DE
MAB_4077|M.abscessus_ATCC_1997 --SPWQPPAQQVPPPAHEQAPTLQNPVAPPPPPVGPPPGEP-------AA
Mb0489c|M.bovis_AF2122/97 AAVKTKRRARRDPLTVFLVLIIVFSLVLAGLIGGELYARHVANSKVAQAV
Rv0479c|M.tuberculosis_H37Rv AAVKTKRRARRDPLTVFLVLIIVFSLVLAGLIGGELYARHVANSKVAQAV
MMAR_0804|M.marinum_M LAGTRKRRSRRDPLSIFLILIIVFSLVLAGVIASELYARHVANGKVAAAV
MUL_4547|M.ulcerans_Agy99 LAGTRKRRSRRDPLSIFLILVIVFSLVLAGVIASELYARHVANGKVAAAV
MLBr_02450|M.leprae_Br4923 --------MLRDPLAIVLILIIVVALVISGLIGAELFARHTANSKVARVV
MAV_4671|M.avium_104 GPAKKKRRFLRDPVSVLLIFIIVFALIIAGFIGAELYVRHVADTKVAQAV
Mvan_0812|M.vanbaalenii_PYR-1 SLPAKLKNIFSDPISIVLVVVIVLALVFAGLLGAELYARNRADTVVAGTV
Mflv_0096|M.gilvum_PYR-GCK SLPAKLKRIFSDPVSVVLVVVIVLALVFAGLLGTELYARNRADTVVAGTI
MSMEG_0923|M.smegmatis_MC2_155 SPKSKVKSLLSDPLSVVLVVVIVLALVVAGVLGGELYARNRADSIVAGIV
TH_2752|M.thermoresistible__bu SFMAKIKSLFSDPLSVVLVVVIVIALVAAGLLGAELYARNRADSVVARVV
MAB_4077|M.abscessus_ATCC_1997 APEPVSPRKGRDYKSLVLIAVIVVAVALAAVLGIELYARQRTSSEVNAAT
* ::.*: :**.:: :..:. **:.*: :. *
Mb0489c|M.bovis_AF2122/97 ACVVKDQATASFGVAPLLLWQVATRHFTNISVETAGNQIRDAKGMQIKLT
Rv0479c|M.tuberculosis_H37Rv ACVVKDQATASFGVAPLLLWQVATRHFTNISVETAGNQIRDAKGMQIKLT
MMAR_0804|M.marinum_M ACEVKDKATASFGVAPLLLWQLATRHFTNITVETAGNQVRDAKGMKLRIS
MUL_4547|M.ulcerans_Agy99 ACEVKDKATASFGVAPLLLWQLATRHFTNITVETAGNQVRDAKGMKLRIS
MLBr_02450|M.leprae_Br4923 TCEIKDQATAKFGVTPLLLWQFATQHFTNISVETAGNQIRDAKGMKIAID
MAV_4671|M.avium_104 ACEVKDQATASFGVTPLMLWQQATKHYTNISVQTAGNNIRDAKGMKLSIN
Mvan_0812|M.vanbaalenii_PYR-1 ECVVQDDATASFGVLPPFLMQHVSGHYTNIRIETAGNQVRDAKGMKVDLD
Mflv_0096|M.gilvum_PYR-GCK ECVVQDDATASFGVMPPFLLQHLSGHYDNIRIETAGNQVRDAKGMKLNID
MSMEG_0923|M.smegmatis_MC2_155 SCVVEDDVKASFDPLPPFLLQHMSGHYTNINIETAGNQIREAKGMKVALD
TH_2752|M.thermoresistible__bu SCVVQDEATASFDPLPPFLMQHMSGHYTNINIETAGNQIRDAKGMKLALH
MAB_4077|M.abscessus_ATCC_1997 SCLVQDGATASFGPMP-LVLQYLGDHIDKLTIKTAGNQIAQAKKMTVAIT
* ::* ..*.*. * :: * * :: ::****:: :** * : :
Mb0489c|M.bovis_AF2122/97 IQNVRLKNTPNSRGTIGALDATITWSSEGIKESVQNA--IPILGAFVTSS
Rv0479c|M.tuberculosis_H37Rv IQNVRLKNTPNSRGTIGALDATITWSSEGIKESVQNA--IPILGAFVTSS
MMAR_0804|M.marinum_M IQDVHLKSTPNSAGTLGALDATISWTSDGIKESVQNA--IPILGEFVTNS
MUL_4547|M.ulcerans_Agy99 IQDVHLKSTPNSAGTLGALDATISWTSDGIKESVQKA--IPILGEFVTNS
MLBr_02450|M.leprae_Br4923 IQNVQIRDTPTSRGTIGVLDAIITWSSDGIRQSVQNS--IPVLGGVVTTS
MAV_4671|M.avium_104 INDVRLKDNGNSKGTIGALDATIDWTTDGIKQSVQNA--IPVLGPFVTNT
Mvan_0812|M.vanbaalenii_PYR-1 INDVRLEDSPTSSGTIGSLVAHITWSAEGIKQTIQGA--IPLVGSFVTG-
Mflv_0096|M.gilvum_PYR-GCK INDVRLEDSATSSGSIGSLVANISWSTEGIRETIQGA--IPLVGSFVNA-
MSMEG_0923|M.smegmatis_MC2_155 IRDVRLEDTPTSTGTVGSLNADITWSTEGIRQTVADMVQLPFIGSAISD-
TH_2752|M.thermoresistible__bu IRDVRLEDTADSGGTLGALDITITWSADGIRRTVQEA--MPLIGSFVTTG
MAB_4077|M.abscessus_ATCC_1997 VRDVSLKKTADSLGTIGRLDVEVSWPTAGITESARAL-VPGMLGSMVGDA
:.:* :... * *::* * : *.: ** .: .:* :
Mb0489c|M.bovis_AF2122/97 VVTHPA-DGTVELKGLLNNITAKPIVAGKGLELQIINFNTLG-FSLPKET
Rv0479c|M.tuberculosis_H37Rv VVTHPA-DGTVELKGLLNNITAKPIVAGKGLELQIINFNTLG-FSLPKET
MMAR_0804|M.marinum_M VVTHPA-DGTIELKGMLNDIIARPVVSGKGLELQIVSFNTLG-FSLPKEA
MUL_4547|M.ulcerans_Agy99 VVTHPA-DGTIELKGMLNDIIARPVVSGKGLELQIVSFNTLG-FSLPKEA
MLBr_02450|M.leprae_Br4923 VTTHPT-NGTIELKGMLNDIVAKPVVSNGGLQLQIVSFNTLG-FSLPKET
MAV_4671|M.avium_104 VTTHPA-DGTIELKGMLDNITAKPVISGTGLQLQIVSFNALG-FTMPKES
Mvan_0812|M.vanbaalenii_PYR-1 VTTNPN-DGTVELEGALGSITARPEVADGGIALRVQQVTGLG-FTLPREA
Mflv_0096|M.gilvum_PYR-GCK VTTDAG-AGTIELEGALGSITAKPVVVNGGLSLQVQQVTGLG-FTLPREA
MSMEG_0923|M.smegmatis_MC2_155 VKTNPS-AGTIELKGLIGTITARPRVVNKGLSLQITELSAIG-LSWPRET
TH_2752|M.thermoresistible__bu VSTDPA-AGTITLDGPLASIVARPQVADGGIRLEVVSLTGIGFLTLPRET
MAB_4077|M.abscessus_ATCC_1997 TTNESTGEVTLSAAGGLAQITTKPVIKDGMVTLQSENVSAFI--GLPREI
. ... *: * : * ::* : . : *. ... : *:*
Mb0489c|M.bovis_AF2122/97 VQSTLNEFTSSLT-KNYPLGIHADSVQVTSTGVVSRFSTRDAAIP--TGI
Rv0479c|M.tuberculosis_H37Rv VQSTLNEFTSSLT-KNYPLGIHADSVQVTSTGVVSRFSTRDAAIP--TGI
MMAR_0804|M.marinum_M VQSTLNDFTADLT-RNYPLGIHADSVQVTTTGVVSHFSTRNATIP--TGS
MUL_4547|M.ulcerans_Agy99 VQSTLNDFTADLT-RNYPLGIHADSVQVTTTGVVSHFSTRNATIP--TGS
MLBr_02450|M.leprae_Br4923 VQFTLDDFTTNLT-KNYPLGIHADNVEVTSTGVTSHFSARNTNIPNSTGG
MAV_4671|M.avium_104 VQSTLDDFTSNLT-KNYPLGIHADSVQVTDKGVTSHFSTRNAAIP--TGN
Mvan_0812|M.vanbaalenii_PYR-1 VQPALDAFTSELT-QDYPMDIRADSVEVTDSGVVSQFSTRNASIP--KQT
Mflv_0096|M.gilvum_PYR-GCK VQPALDAFTERLT-QDYPMDIRADSVEVTDSGVVSQFSTSNASIP--KSQ
MSMEG_0923|M.smegmatis_MC2_155 LQPILDSFTSQLT-ENYPMGIHADSVQVTDSGVVARFSTQNAAMP--KGE
TH_2752|M.thermoresistible__bu VQPVLDAFTDGLT-DNYPMDITAQSVQVTDDGVIAQLSSRNASIP--KGQ
MAB_4077|M.abscessus_ATCC_1997 IQPALDTFSKGLVGGQYPMGLKAQEVKVTNDGITVKLSSTNQPMK----P
:* *: *: *. :**:.: *:.*:** *: ::*: : :
Mb0489c|M.bovis_AF2122/97 QN-PCFSHI--
Rv0479c|M.tuberculosis_H37Rv QN-PCFSHI--
MMAR_0804|M.marinum_M QN-PCFANL--
MUL_4547|M.ulcerans_Agy99 QN-PCFANL--
MLBr_02450|M.leprae_Br4923 QD-PCFANL--
MAV_4671|M.avium_104 NNDPCFANL--
Mvan_0812|M.vanbaalenii_PYR-1 DD-PCFAGL--
Mflv_0096|M.gilvum_PYR-GCK QD-PCFAGL--
MSMEG_0923|M.smegmatis_MC2_155 ED-PCFAGI--
TH_2752|M.thermoresistible__bu ED-PCFAEL--
MAB_4077|M.abscessus_ATCC_1997 TNEPCLQNLSF
: **: :