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IEAGEPNDLPSLWSHEPHAELMFQPGDKVADIDTEATPGFRGTKSDAPTLQAERNVRFAELQEKLYANSR SGDTRSVLLVLQGMDTAGKGGIVKHVVGGGNPQGIQYRSFGKPTAEELAHHYLWRIRKALPAAGHIGVFD RSHYEDVLIVRVHNLVPPDVWQPRYDEINAFERELVNQGTSIVKVAMFVSLDEQKRRLAARLERPDKYWK YNPADIDERLKWPAYQEAYQAMLDRTSTAYAPWHIVPCNRKWYSRLAITELLIETLKRLNMSWPPPDFDV AAEKKRLASA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0804 | - | - | 100% (291) | hypothetical protein Mvan_0804 |
| M. vanbaalenii PYR-1 | Mvan_0772 | - | 5e-27 | 33.05% (236) | hypothetical protein Mvan_0772 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3261c | pvdS | 6e-24 | 31.82% (242) | transcriptional regulatory protein PvdS |
| M. gilvum PYR-GCK | Mflv_0104 | - | 1e-156 | 90.56% (286) | hypothetical protein Mflv_0104 |
| M. tuberculosis H37Rv | Rv3232c | pvdS | 6e-24 | 31.82% (242) | transcriptional regulatory protein PvdS |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4087 | - | 1e-110 | 67.78% (270) | hypothetical protein MAB_4087 |
| M. marinum M | MMAR_1312 | pvdS | 8e-22 | 30.48% (210) | transcriptional regulatory protein PvdS |
| M. avium 104 | MAV_4195 | - | 7e-24 | 31.16% (199) | polyphosphate kinase 2 |
| M. smegmatis MC2 155 | MSMEG_0915 | - | 1e-136 | 80.28% (284) | polyphosphate kinase 2 superfamily protein |
| M. thermoresistible (build 8) | TH_1923 | - | 1e-104 | 70.97% (248) | polyphosphate kinase 2 superfamily protein |
| M. ulcerans Agy99 | MUL_2568 | pvdS | 6e-22 | 30.48% (210) | transcriptional regulatory protein PvdS |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1312|M.marinum_M ------------------------MSTATNDGAPAKAKKKKKKSAGAGRH
MUL_2568|M.ulcerans_Agy99 ------------------------MSTATNDGAPAKAKKKKKKSAGAGRH
MAV_4195|M.avium_104 ------------------------MSSAKNDGVPLKAGKKKSARAAV---
Mb3261c|M.bovis_AF2122/97 -----------------MDIPSVDVSTATNDGASSRAKGHR--SAAPGRR
Rv3232c|M.tuberculosis_H37Rv -----------------MDIPSVDVSTATNDGASSRAKGHR--SAAPGRR
Mvan_0804|M.vanbaalenii_PYR-1 MIEAGE---PNDLPSLWSHEPHAELMFQPGDKVADIDTEATPGFRGTKSD
Mflv_0104|M.gilvum_PYR-GCK ---MTE---PDDLPSLWSHEPHVELRFRPGDRVADIDADATPGFRGDKSD
MSMEG_0915|M.smegmatis_MC2_155 MSDFDDDDLAGDLPTLWTHEPHQHLAFRQGDQVSRIKTDGTPGFRGSKSD
TH_1923|M.thermoresistible__bu -------------------------LFRSXX--------------XGKAD
MAB_4087|M.abscessus_ATCC_1997 ---------------MTQKFDTSALRYRPGLTFADVDSRATPGFDGSRED
MMAR_1312|M.marinum_M KISKSVYEAELFRLQTEFVRLQEWVRHAGARVVVIFEGRDAAGKGGAIKR
MUL_2568|M.ulcerans_Agy99 KISKGVYEAELFRLQTEFVRLQEWVRHAGARVVVIFEGRDAAGKGGAIKR
MAV_4195|M.avium_104 KIPDAVYEAELFRLQTELVKLQEWVRHSGARLVVVFEGRDAAGKGGAIKR
Mb3261c|M.bovis_AF2122/97 KISDAVYQAELFRLQTEFVKLQEWARHSGARLVVIFEGRDGAGKGGAIKR
Rv3232c|M.tuberculosis_H37Rv KISDAVYQAELFRLQTEFVKLQEWARHSGARLVVIFEGRDGAGKGGAIKR
Mvan_0804|M.vanbaalenii_PYR-1 APTLQAERNVRFAELQEKLYANSRSGD-TRSVLLVLQGMDTAGKGGIVKH
Mflv_0104|M.gilvum_PYR-GCK APTLQAERNVRFAELQEMLYANSRSGD-TRSVLLVLQGMDTAGKGGIVKH
MSMEG_0915|M.smegmatis_MC2_155 AATLQVERNLRLASLQEMLYARSKAGDDNRSVLLILQGMDTAGKGGIVKH
TH_1923|M.thermoresistible__bu APALQTERSARLAELQEMLYANHRVRGDRRSVLLVLQGMDTAGKGGIVKH
MAB_4087|M.abscessus_ATCC_1997 GEALQAELSGRLGLLQEMLYANGRSGD-HRSVLLVLQGMDTSGKGGIVKH
. . : * : . ::::::* * :**** :*:
MMAR_1312|M.marinum_M ITEYLSPRHAYVAALPVPNDRERGQWYYQRYIAHLPAKGEIVFFDRSWYN
MUL_2568|M.ulcerans_Agy99 ITEYLSPRHAYVAALPVPNDRERGQWYYQRYIAHLPAKGEIVFFDRSWYN
MAV_4195|M.avium_104 ITEYLSPRVARVAALPVPTDRERGQWYYQRYIAHLPSKGEIVLFDRSWYN
Mb3261c|M.bovis_AF2122/97 ITEYLNPRVARIAALPAPTDRERGQWYYQRYIAHLPAKGEIVLFDRSWYN
Rv3232c|M.tuberculosis_H37Rv ITEYLNPRVARIAALPAPTDRERGQWYYQRYIAHLPAKGEIVLFDRSWYN
Mvan_0804|M.vanbaalenii_PYR-1 VVGGGNPQGIQYRSFGKPTAEELAHHYLWRIRKALPAAGHIGVFDRSHYE
Mflv_0104|M.gilvum_PYR-GCK VVGGCNPQGVQYRSFGKPTAEELAHHYLWRIRKALPSAGHIGVFDRSHYE
MSMEG_0915|M.smegmatis_MC2_155 VVGAANPQGVRYTSFGKPTEEERAHHYLWRIRNALPPAGHIGVFDRSHYE
TH_1923|M.thermoresistible__bu VVGAVNPMGVRYRAFGPPTAEEKARHYLWRVRRALPPPGHLGVFDRSHYE
MAB_4087|M.abscessus_ATCC_1997 VVGQVDPQGMAHASFGVPTEDERKHHYLWRIRNALPSGGQLGVFDRSHYE
:. .* :: *. * : * * **. *.: .**** *:
MMAR_1312|M.marinum_M RAGIEKVMGFCTPQEHALFLRQTPIFEQMLIDDGILLRKYWFSVSDEEQL
MUL_2568|M.ulcerans_Agy99 RAGIEKVMGFCTPQEHALFLRQTPIFEQMLIDDGILLRKYWFSVSDEEQL
MAV_4195|M.avium_104 RAGIEKVMGFCTPQEYVLFLRQTPIFEQMLIDDGILLRKYWFSVSEAEQL
Mb3261c|M.bovis_AF2122/97 RAGVEKVMGFCTPQEYVLFLRQTPIFEQMLIDDGILLRKYWFSVSDAEQL
Rv3232c|M.tuberculosis_H37Rv RAGVEKVMGFCTPQEYVLFLRQTPIFEQMLIDDGILLRKYWFSVSDAEQL
Mvan_0804|M.vanbaalenii_PYR-1 DVLIVRVHNLVPPDVWQPRYDEINAFERELVNQGTSIVKVAMFVSLDEQK
Mflv_0104|M.gilvum_PYR-GCK DVLIVRVHNLVPPEVWEPRYDEINAFERELVDGGTTLVKVAMFVSLDEQK
MSMEG_0915|M.smegmatis_MC2_155 DVLIVRVHNLVPPEVWSARYDEINEFERELVDAGTTLVKVAMFVSLAEQK
TH_1923|M.thermoresistible__bu DVLVVRVHNLVPPEVWSDRYDEINAFERELVDAGMTLVKVALFISPAEQR
MAB_4087|M.abscessus_ATCC_1997 DVLVVRVHNLVAPEVWGARYEEINPFEKELTEAGTTILKVVLVVSLDEQK
. : :* .: .*: : **: * : * : * : :* **
MMAR_1312|M.marinum_M HRFKARQTDPVRQWKLSPMDLESVYRWEDYSRAKDEMMVHTDTPVSPWYV
MUL_2568|M.ulcerans_Agy99 HRFKARQTDPVRQWKLSPMDLESVYRWEDYSRAKDEMMVHTDTPVSPWYV
MAV_4195|M.avium_104 RRFKARLKDPVRRWKLSPIDLESVYRWEDYSRAKDEMMVHTDTPESPWYV
Mb3261c|M.bovis_AF2122/97 RRFKARRNDPVRQWKLSPMDLESVYRWEDYSRAKDEMMVHTDTPVSPWYV
Rv3232c|M.tuberculosis_H37Rv RRFKARRNDPVRQWKLSPMDLESVYRWEDYSRAKDEMMVHTDTPVSPWYV
Mvan_0804|M.vanbaalenii_PYR-1 RRLAARLERPDKYWKYNPADIDERLKWPAYQEAYQAMLDRTSTAYAPWHI
Mflv_0104|M.gilvum_PYR-GCK KRLAERLERPDKYWKYNPGDIDERLKWPAYQEAYQAMLDRTSTDHAPWHI
MSMEG_0915|M.smegmatis_MC2_155 NRLAERLERPDKYWKYNPADIDERLLWPKYQEAYQAMLEKTSTDHAPWHI
TH_1923|M.thermoresistible__bu KNLLARLEDPAKHWKYSPSDVDERRHWPAYQAAYQDMLDRTSTVYAPWFV
MAB_4087|M.abscessus_ATCC_1997 RRLAERLDRPDKYWKFNPNDIDERAFWPAYQDAYQAVLEKTSTAHAPWYV
..: * * : ** .* *::. * *. * : :: :*.* :**.:
MMAR_1312|M.marinum_M VESDIKKHARLNMMAHLLSTIDYRPVEMPKVNLPDQPIVTGNYKRPPREL
MUL_2568|M.ulcerans_Agy99 VESDIKKHARLNMMAHLLSTIDYRPVEMPKVNLPDQPIVTGNYKRPPREL
MAV_4195|M.avium_104 VESDIKKHARLNMMAHLLSTIPYHAVEAPPVKLPRRPVVTGNYQRPPREL
Mb3261c|M.bovis_AF2122/97 VESDIKKHARLNMMAHLLSTIDYADVEKPKVKLPPRPLVSGNYRRPPREL
Rv3232c|M.tuberculosis_H37Rv VESDIKKHARLNMMAHLLSTIDYADVEKPKVKLPPRPLVSGNYRRPPREL
Mvan_0804|M.vanbaalenii_PYR-1 VPCNRKWYSRLAITELLIETLKRLNMSWP----PPDFDVAAEKKRLASA-
Mflv_0104|M.gilvum_PYR-GCK VPCNRKWYSRLAITELMIEALKGLNMAWP----PPDFDVAAEKKRLASA-
MSMEG_0915|M.smegmatis_MC2_155 VPCNRKWYSRLAITELLIEALKRLNMSWP----PPDFDVEAEKRRLAEA-
TH_1923|M.thermoresistible__bu VPGDRRWYSRLAVTELLIDALAGMGLSWP----PADFDVEAERNRLLRA-
MAB_4087|M.abscessus_ATCC_1997 IPCDRKWYSRLAVTALLDETLDGLNLSWP----PADFDIEEQKRRLAQA-
: : : ::** : : .:: : * * : : .*
MMAR_1312|M.marinum_M SKYVEDYASTLIGR
MUL_2568|M.ulcerans_Agy99 SKYVEDYASTLIGR
MAV_4195|M.avium_104 SRYVDDYAATLI--
Mb3261c|M.bovis_AF2122/97 STYVDDYVATLIAR
Rv3232c|M.tuberculosis_H37Rv STYVDDYVATLIAR
Mvan_0804|M.vanbaalenii_PYR-1 --------------
Mflv_0104|M.gilvum_PYR-GCK --------------
MSMEG_0915|M.smegmatis_MC2_155 --------------
TH_1923|M.thermoresistible__bu --------------
MAB_4087|M.abscessus_ATCC_1997 --------------