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KRWVSALRLEATLQVRQRFVHAAVISGMLWLVVLLPMPQHLRSIVEPYVLIGDITIVGFFFIGGAVFFEK QERTLGAVICSPLRFIEYLSVKILVLTGVSLFIAVVVTLATHGTDFRPGFLVAGVVLGTLVMLLVGFISA LPFDSVSDWFLSTVVPLLILSLPVMYMLGVWTNPAFYLVPTQGPLLMFLAVFDQVSLAPWQVGYAVLYPL ICAAGLYRLARVMFGRYVVERSGVA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0775 | - | - | 100% (236) | putative antibiotic-transport integral membrane leucine and valine rich protein ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2706c | - | 1e-89 | 65.68% (236) | antibiotic ABC transporter transmembrane protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2687c | - | 1e-89 | 65.68% (236) | antibiotic ABC transporter transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1859 | - | 2e-78 | 59.40% (234) | antibiotic ABC transporter membrane protein |
| M. marinum M | MMAR_2027 | - | 5e-81 | 60.26% (234) | antibiotic-transport integral membrane leucine and valine rich |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1503 | - | 7e-83 | 61.02% (236) | antibiotic ABC transporter transmembrane protein |
| M. thermoresistible (build 8) | TH_1291 | cydB | 4e-06 | 26.00% (200) | Probable integral membrane cytochrome D ubiquinol oxidase |
| M. ulcerans Agy99 | MUL_3325 | - | 8e-72 | 61.35% (207) | antibiotic-transport integral membrane leucine and valine rich |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2706c|M.bovis_AF2122/97 MTRLVPALRLELTLQVRQKFLHAAVFSGLIWLAVLLPMPVSLRPVAEP--
Rv2687c|M.tuberculosis_H37Rv MTRLVPALRLELTLQVRQKFLHAAVFSGLIWLAVLLPMPVSLRPVAEP--
MSMEG_1503|M.smegmatis_MC2_155 MTRLWAALRLELTVQTRQKFLHAAVFSGLIWLAVLLPLPHSVRPVVEP--
MMAR_2027|M.marinum_M MSRLSTALRLELTLQNRQRFLHAAVFSGLIWLAVLLPMPADLRSVAEP--
MUL_3325|M.ulcerans_Agy99 MSRLSTALRLELTLQNRQRFLHAAVFSGLIWLAVLLPMPADLRSVAEP--
MAB_1859|M.abscessus_ATCC_1997 MNRFSQALRLELTLQVRQKFLHAAVFSGFIWLAVLLPMSRSLRSAAEP--
Mvan_0775|M.vanbaalenii_PYR-1 MKRWVSALRLEATLQVRQRFVHAAVISGMLWLVVLLPMPQHLRSIVEP--
TH_1291|M.thermoresistible__bu --VISVGLQELWFILIAALFLGFLVLEGFDFGVGMLMGPLGAAGEGDPEP
.*: : *: *:.*: : . :* . :*
Mb2706c|M.bovis_AF2122/97 ------------------YVLVGDIAIIGFFFVGGTVFFEKQERTIGAIV
Rv2687c|M.tuberculosis_H37Rv ------------------YVLVGDIAIIGFFFVGGTVFFEKQERTIGAIV
MSMEG_1503|M.smegmatis_MC2_155 ------------------YVLIGDVAIIGFFFIGGAVFFEKQERTLGAII
MMAR_2027|M.marinum_M ------------------YVLSGDITIIGFFFVAGTVFFEKQERTLSAVI
MUL_3325|M.ulcerans_Agy99 ------------------YVLSGDITIIGFFFAAGTVFFEKQERTLSAVI
MAB_1859|M.abscessus_ATCC_1997 ------------------YILIGDISIIGFFFIAGTVFFEKQEHTLGAVI
Mvan_0775|M.vanbaalenii_PYR-1 ------------------YVLIGDITIVGFFFIGGAVFFEKQERTLGAVI
TH_1291|M.thermoresistible__bu RRRAVLNTIGPVWDANEVWLITAGASMFAAFPNWYATLFSALYLPLLAIL
::: .. ::.. * :.:*. .: *::
Mb2706c|M.bovis_AF2122/97 S-------------------------------------------------
Rv2687c|M.tuberculosis_H37Rv S-------------------------------------------------
MSMEG_1503|M.smegmatis_MC2_155 S-------------------------------------------------
MMAR_2027|M.marinum_M A-------------------------------------------------
MUL_3325|M.ulcerans_Agy99 A-------------------------------------------------
MAB_1859|M.abscessus_ATCC_1997 C-------------------------------------------------
Mvan_0775|M.vanbaalenii_PYR-1 C-------------------------------------------------
TH_1291|M.thermoresistible__bu FGMIVRIVGIEWRGKIDDERWRKWADAGIAVGSWLPAVLWGVAFAILLRG
Mb2706c|M.bovis_AF2122/97 -------------TPLRFWEYLAAKLTVLLAISLFVAVVVATIVHGLGYH
Rv2687c|M.tuberculosis_H37Rv -------------TPLRFWEYLAAKLTVLLAISLFVAVVVATIVHGLGYH
MSMEG_1503|M.smegmatis_MC2_155 -------------TPLRFAEYLTAKLTVLAAISLFVAVVVATITHGLTYH
MMAR_2027|M.marinum_M -------------TPLRFGEYLAAKLAVLLMVSVGVAVVVATIAHGLSYS
MUL_3325|M.ulcerans_Agy99 -------------TPLRFGEYLAAKLAVLLMVSVGVAVVVATIAHGFSYS
MAB_1859|M.abscessus_ATCC_1997 -------------TPLRFREYLSAKLVVLLAISLVVGVGVSTVANGFHYR
Mvan_0775|M.vanbaalenii_PYR-1 -------------SPLRFIEYLSVKILVLTGVSLFIAVVVTLATHGTDFR
TH_1291|M.thermoresistible__bu LPIDADGRAHPGLTDVLNGYTLLGGLATASLFAFYGAVFVALKTAGSVRA
: : * : . .:. .* *: . *
Mb2706c|M.bovis_AF2122/97 LLPLVAGIVLGTLLMLLVGFSSSLPFASVTDWFLAAV-IPLAIMLAPPVV
Rv2687c|M.tuberculosis_H37Rv LLPLVAGIVLGTLLMLLVGFSSSLPFASVTDWFLAAV-IPLAIMLAPPVV
MSMEG_1503|M.smegmatis_MC2_155 AAALIGGVLLGTLLMLVVGFISSLPFASVSDWAMATV-IPLAVMLVPPIL
MMAR_2027|M.marinum_M AAPMIVAVALGTLLMLLVGFISSLPFASISDWFLVAT-IPLAVMNLP-VL
MUL_3325|M.ulcerans_Agy99 AAPMIVAVALGTLLMLLVGFISSLPFASISDWFLVAT-IPLAVMNLP-VL
MAB_1859|M.abscessus_ATCC_1997 PLPLLVGVVLGSLLMLLSGFLTSLPFASISDWFLAAT-IPLAILTLP-IL
Mvan_0775|M.vanbaalenii_PYR-1 PGFLVAGVVLGTLVMLLVGFISALPFDSVSDWFLSTV-VPLLILSLP-VM
TH_1291|M.thermoresistible__bu DAFRFAKWLSAPVIVLAGGFGLWTQLAHGTDWTWVALGVAVVALLVAVGL
. ..:::* ** : :** : :.: : . :
Mb2706c|M.bovis_AF2122/97 HYSG---LWPNPVLYLIPTQGPLLLLGAAFD-------------------
Rv2687c|M.tuberculosis_H37Rv HYSG---LWPNPVLYLIPTQGPLLLLGAAFD-------------------
MSMEG_1503|M.smegmatis_MC2_155 HYSG---VWTHPVLYAAPMQGPMLLLGAAFD-------------------
MMAR_2027|M.marinum_M YYSG---VWPHPVLYAIPTQGPLLLLGAAFG-------------------
MUL_3325|M.ulcerans_Agy99 YYSG---VWPHPVLYAIPTQGPLLLLGAAFG-------------------
MAB_1859|M.abscessus_ATCC_1997 GFSG---LWNTPGLYVVPTYGPLLLFGAAFG-------------------
Mvan_0775|M.vanbaalenii_PYR-1 YMLG---VWTNPAFYLVPTQGPLLMFLAVFD-------------------
TH_1291|M.thermoresistible__bu MWAGRREGWAFFNTVVVITAVTVLIFGAMYPNLLPSTLNPEWSVTIYNGS
* * .:*:: * :
Mb2706c|M.bovis_AF2122/97 ----QVSLAPWQVGYAVVYPIVCAAGLCRAAKALFGRYVVQRSGVL--
Rv2687c|M.tuberculosis_H37Rv ----QVSLAPWQVGYAVVYPIVCAAGLCRAAKALFGRYVVQRSGVL--
MSMEG_1503|M.smegmatis_MC2_155 ----QSVLNAWQIGYAVAYPLACLAGLWWAAHAMFDHYVVERSGVL--
MMAR_2027|M.marinum_M ----QLTLAPWQIGYALLYPSVCVGVLYRVAEASFARYVVAAAGSW--
MUL_3325|M.ulcerans_Agy99 ----QLTLAPWQIGYALF---VSVGVCRGAVSSG--------------
MAB_1859|M.abscessus_ATCC_1997 ----QVELTPWLAVYAVGYPVLGIAGLSWLCKIAFGKYVVAQSGGMS-
Mvan_0775|M.vanbaalenii_PYR-1 ----QVSLAPWQVGYAVLYPLICAAGLYRLARVMFGRYVVERSGVA--
TH_1291|M.thermoresistible__bu STPYTLQIMSWAALTLLPLVLGYQAWTYWVFRKRISTDAIPPPIGLPR
: .* : .