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MPKNLARALGAAALTGCGVLAAPPVVADADRPTPPLLYGFYDVSVDFSKQTFNGAPTPMPAKTFQVEYTA RCDVAGCAVSMDNSDDLSRNPGAPTVFEYRWNNDRWETSGDYPYLCDRMNPASAVQSVRSDYLIPNPDGS FSGERTITVGGAGCPGEGPGTHWLPITVTPISPPSGHPTGPPTGPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0448 | - | - | 100% (186) | hypothetical protein Mvan_0448 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2938c | pknI | 3e-06 | 25.17% (151) | transmembrane serine/threonine-protein kinase I |
| M. gilvum PYR-GCK | Mflv_2173 | - | 2e-06 | 24.69% (162) | hypothetical protein Mflv_2173 |
| M. tuberculosis H37Rv | Rv2914c | pknI | 3e-06 | 25.17% (151) | transmembrane serine/threonine-protein kinase I |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3799c | - | 2e-45 | 51.81% (166) | hypothetical protein MAB_3799c |
| M. marinum M | MMAR_4124 | - | 2e-05 | 26.55% (177) | hypothetical protein MMAR_4124 |
| M. avium 104 | MAV_3145 | - | 9e-05 | 26.38% (163) | PknF protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3799c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2938c|M.bovis_AF2122/97 --------------------------------------------------
Rv2914c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3145|M.avium_104 MNEHKGTTRRIGAGRRLLSNPRQARAALRAGFQSLPGMPIGQLFRRIPPV
Mflv_2173|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4124|M.marinum_M --------------------------------------------------
Mvan_0448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3799c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2938c|M.bovis_AF2122/97 ---------------------MALASGVTFAGYTVVRMLGCSAMGEVYLV
Rv2914c|M.tuberculosis_H37Rv ---------------------MALASGVTFAGYTVVRMLGCSAMGEVYLV
MAV_3145|M.avium_104 DSRPHPEPAAAQGNSEPGGPRLTIGNGASFAGYTILRQLGAGGMAEVYLA
Mflv_2173|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4124|M.marinum_M --------------------------------------------------
Mvan_0448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3799c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2938c|M.bovis_AF2122/97 QHPGFPGWQALKVLSPAMAADDEFRRRFQRETEVAARLFHPHILEVHDRG
Rv2914c|M.tuberculosis_H37Rv QHPGFPGWQALKVLSPAMAADDEFRRRFQRETEVAARLFHPHILEVHDRG
MAV_3145|M.avium_104 LHPRLPRRDVIKVLAEAVTVDPEFRERFNREADLAATLWHPHIVGVHDRG
Mflv_2173|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4124|M.marinum_M --------------------------------------------------
Mvan_0448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3799c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2938c|M.bovis_AF2122/97 EFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTAVAGALDYAH
Rv2914c|M.tuberculosis_H37Rv EFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTAVAGALDYAH
MAV_3145|M.avium_104 EFNGHLWISMDYVEGTDASRLVKESYADGMPLDEVSAIVQAVAGALDYAH
Mflv_2173|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4124|M.marinum_M --------------------------------------------------
Mvan_0448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3799c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2938c|M.bovis_AF2122/97 QRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQP-------------
Rv2914c|M.tuberculosis_H37Rv QRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQP-------------
MAV_3145|M.avium_104 ARGLLHRDVKPANILLTHPEAGERRILLADFGVARHLGDISGITETNVAV
Mflv_2173|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4124|M.marinum_M --------------------------------------------------
Mvan_0448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3799c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2938c|M.bovis_AF2122/97 ---SYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQ--
Rv2914c|M.tuberculosis_H37Rv ---SYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQ--
MAV_3145|M.avium_104 GTVAYAAPEQLTGSPIDGRADQYALAATAFHLLTGAPPFQHSNPIAVIGQ
Mflv_2173|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4124|M.marinum_M --------------------------------------------------
Mvan_0448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3799c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2938c|M.bovis_AF2122/97 -----PPKLSAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAG
Rv2914c|M.tuberculosis_H37Rv -----PPKLSAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAG
MAV_3145|M.avium_104 HLHEDPPRLSDFRPELAALDEVFCQALAKVPEDRFDRCRAFAAAVSREC-
Mflv_2173|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4124|M.marinum_M --------------------------------------------------
Mvan_0448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3799c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2938c|M.bovis_AF2122/97 VAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPSARAPAP
Rv2914c|M.tuberculosis_H37Rv VAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPSARAPAP
MAV_3145|M.avium_104 --------------DGAAAIG---------------------PDARSRTV
Mflv_2173|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4124|M.marinum_M --------------------------------------------------
Mvan_0448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3799c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2938c|M.bovis_AF2122/97 AAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVA
Rv2914c|M.tuberculosis_H37Rv AAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVA
MAV_3145|M.avium_104 ASPAHRRRG-----PGRVIAAVTHRFSPQTRWAAA---------LVCAVL
Mflv_2173|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4124|M.marinum_M --------------------------------------------------
Mvan_0448|M.vanbaalenii_PYR-1 ----------------MPKNLARALGAAALTGCGVLAAPPVVADADRPTP
MAB_3799c|M.abscessus_ATCC_199 ---------------------MRRCGAAALAAIGALTG-AWAARADRPEP
Mb2938c|M.bovis_AF2122/97 VLLLAGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVP
Rv2914c|M.tuberculosis_H37Rv VLLLAGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVP
MAV_3145|M.avium_104 VAVAATWSVL----------YSFQPGAPPAN-PALASKPSPPAAVAAPIA
Mflv_2173|M.gilvum_PYR-GCK ---------------MLARRAR-----HALTAAAVVAAAAVCGAAT-AAA
MMAR_4124|M.marinum_M ---------------MDTMRARSRLRLQVLGVLGGIAAAMFAPPSTPAHA
. : . .
Mvan_0448|M.vanbaalenii_PYR-1 --PLLYGFYDVSVDFSKQTFNGAPTPM--PAKTFQVEYTARCDVAGCAVS
MAB_3799c|M.abscessus_ATCC_199 --VPLYGAYDTYLDHARQTFEGRPDPS--APSTQAASFTTTCTAQGCVAH
Mb2938c|M.bovis_AF2122/97 ----LDGTYRIEIQRSKQTYDYTPTPQP-PDVNTWWAFRTSCTPTECLAA
Rv2914c|M.tuberculosis_H37Rv ----LDGTYRIEIQRSKQTYDYTPTPQP-PDVNTWWAFRTSCTPTECLAA
MAV_3145|M.avium_104 GGPVLNGTYKLDYDQTKRTTNGIGIRHD-GAGTNWWAFRSACTSSGCAAT
Mflv_2173|M.gilvum_PYR-GCK APPDWNGRYTVVTFASQKIGTSIATRQPEPDFSAQYTFSTSC-VGTCVAT
MMAR_4124|M.marinum_M AMPMWNGKYSLVRYAEQKAGTSMAASQMEPTFSADYVFVTACSAEQCVAT
* * :: . : : * * .
Mvan_0448|M.vanbaalenii_PYR-1 MDNSDD----LSRNPGAPTVFEYRWNNDRWETSGD---YPYLCDRMNPAS
MAB_3799c|M.abscessus_ATCC_199 WLRVAE----LSDNPHAPALFDYRWNGDRWESSAD---YPFHCG---AGG
Mb2938c|M.bovis_AF2122/97 ATMLDDNDHTQAKTPP-VRPFLMQFGEGQWKSRPETVQFPCVGPNGSP-S
Rv2914c|M.tuberculosis_H37Rv ATMLDDNDHTQAKTPP-VRPFLMQFGEGQWKSRPETVQFPCVGPNGSP-S
MAV_3145|M.avium_104 GTRLDDATHQAAGGPDGDQTDTLRFVGGYWQGAPEQQRVGCTRPGGPAGA
Mflv_2173|M.gilvum_PYR-GCK ASDGPA-----PSNPTIPQPTRYTWDGRQWIFNYN-WQWECFRGEGLPRE
MMAR_4124|M.marinum_M ATNGPT-----PKNPTLPQPSRYFWDGAKWVERFD-FQWDCYMGEGAAKV
. * : * : .
Mvan_0448|M.vanbaalenii_PYR-1 AVQSVRSDYLIPNPDGSFSGERTITVGGAGCPGEGPGTHWLPITVTPISP
MAB_3799c|M.abscessus_ATCC_199 TVTAARSDFLIPNGDGSFSGERTFTVGAPGCPGDGPGTYWLPFTLTPTS-
Mb2938c|M.bovis_AF2122/97 TQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIPAVASRSGDL
Rv2914c|M.tuberculosis_H37Rv TQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIPAVASRSGDL
MAV_3145|M.avium_104 TQQETIARSLAPQSDGTLRGTETETVLSNECGAQGAVVRVPVVATRVGDV
Mflv_2173|M.gilvum_PYR-GCK YAAARSLVFYAPTADGSMYGTWRTEILDGVCKG---TVVMPVAAYPV---
MMAR_4124|M.marinum_M WAPARSWAYYAPQPDGSLRGTWHTDIVGGPCQG---TVQMPVAALPAGS-
* :* : * : * :
Mvan_0448|M.vanbaalenii_PYR-1 PSGHPTGPPTGPR-------------------------------------
MAB_3799c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2938c|M.bovis_AF2122/97 PPAVTVPDPATIP-------------------------------------
Rv2914c|M.tuberculosis_H37Rv PPAVTVPDPATIP-------------------------------------
MAV_3145|M.avium_104 PPGVTVADPASVINASPTATAPAPPVLGGLCSDVGKVAYDPTNNEQIVCE
Mflv_2173|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4124|M.marinum_M --------------------------------------------------
Mvan_0448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3799c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2938c|M.bovis_AF2122/97 --------------------DTPDTTSTATLT----------PPTTTAPG
Rv2914c|M.tuberculosis_H37Rv --------------------DTPDTTSTATLT----------PPTTTAPG
MAV_3145|M.avium_104 GSSWAKAPITMGVHAAGSSCDRPGTSVFAMSTSSDGYLLQCDPVTRTWTR
Mflv_2173|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4124|M.marinum_M --------------------------------------------------
Mvan_0448|M.vanbaalenii_PYR-1 ---
MAB_3799c|M.abscessus_ATCC_199 ---
Mb2938c|M.bovis_AF2122/97 PGR
Rv2914c|M.tuberculosis_H37Rv PGR
MAV_3145|M.avium_104 PAG
Mflv_2173|M.gilvum_PYR-GCK ---
MMAR_4124|M.marinum_M ---