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TGWAATVGADVITVADVDAREDLLRAGDRAHALPGPGTGEARQLRRWLTQVLVAERIVAASPGADPAPSE QDLLLDEVGLMELGSVAAATLATPHGRAVYASVTAEVQVGADAVSDYFARNPYRFAHGAARPGVWRGPSS PPRFDDVRALIHAHLLAAARRREYRRWLDAQCAALVTLADGYEHPGDPRQPDNTHRH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5103 | - | - | 100% (198) | putative malonyl CoA-acyl carrier protein transacylase FabD2 (MCT) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0668 | fabD2 | 5e-54 | 57.29% (199) | putative malonyl CoA-acyl carrier protein transacylase |
| M. tuberculosis H37Rv | Rv0649 | fabD2 | 6e-54 | 57.29% (199) | malonyl CoA-acyl carrier protein transacylase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0986 | fabD2 | 1e-51 | 55.78% (199) | malonyl CoA-acyl carrier protein transacylase, FabD2 |
| M. avium 104 | MAV_4511 | - | 6e-49 | 52.76% (199) | FabD2 protein |
| M. smegmatis MC2 155 | MSMEG_1362 | - | 7e-56 | 57.58% (198) | hypothetical protein MSMEG_1362 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0738 | fabD2 | 2e-37 | 54.00% (150) | malonyl CoA-acyl carrier protein transacylase, FabD2 |
| M. vanbaalenii PYR-1 | Mvan_1250 | - | 1e-67 | 66.67% (201) | FabD2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0668|M.bovis_AF2122/97 MSGRSRLPGSSSRRDAARIVAERVVATVAGVAVAVDEVDAAEARLRDGPR
Rv0649|M.tuberculosis_H37Rv MSGRSRLPGSSSRRDAARIVAERVVATVAGVAVAVDEVDAAEARLRDGPR
MMAR_0986|M.marinum_M -------------------MTGSLVATVAGAPIAVGEVDAREARLRNGPR
MUL_0738|M.ulcerans_Agy99 --------------------------------------------------
MAV_4511|M.avium_104 -------------------MSGHPVATVAGVPVSSVEVDAAEARLRGGRG
MSMEG_1362|M.smegmatis_MC2_155 --------------------MRAVAARVAGSAVFVDEIDERERRLRASNL
Mflv_5103|M.gilvum_PYR-GCK --------------------MTGWAATVGADVITVADVDAREDLLRAGDR
Mvan_1250|M.vanbaalenii_PYR-1 --------------------MSAVAATVGSHVITVADVDARERAVRAGVR
Mb0668|M.bovis_AF2122/97 AAALPASGTSEGRQLRRWLTQLIVTERVVAAEAAARGLTAAGAPAEADLL
Rv0649|M.tuberculosis_H37Rv AAALPASGTSEGRQLRRWLTQLIVTERVVAAEAAARGLTAAGAPAEADLL
MMAR_0986|M.marinum_M AAALPVSGTSEGRQLRRWLAQLIATERVLADEATARGVTGHPAPSEAELL
MUL_0738|M.ulcerans_Agy99 ---------------------MIATERVLADEATARGVTGHPAPSEAELL
MAV_4511|M.avium_104 AAALPPPGTSEGRQLRRWLTQLIVTRRVIAAEAAARGLTPAGAPNEAELL
MSMEG_1362|M.smegmatis_MC2_155 ASALPRPGTSEGRQLRRWLTQLAVAERVVAAEVAG-----DVAPAEGELL
Mflv_5103|M.gilvum_PYR-GCK AHALPGPGTGEARQLRRWLTQVLVAERIVAASPG-----ADPAPSEQDLL
Mvan_1250|M.vanbaalenii_PYR-1 GDALPRPGAGEARQLRRWLTQVLVAEQVVAMWQGP--VDLDAAPFADDLL
: .:.:::* ** :**
Mb0668|M.bovis_AF2122/97 PDATARLEIGSVAAAVLADPLARALFAAVTARVAVTDDAVADYHARNPLR
Rv0649|M.tuberculosis_H37Rv PDATARLEIGSVAAAVLADPLARALFAAVTARVAVTDDAVADYHARNPLR
MMAR_0986|M.marinum_M PDVTARLEIGSVAAAVLADPRVRALFAEVTADVRVGDDEVAAYHARNPLR
MUL_0738|M.ulcerans_Agy99 PDVTARLEIGSVAAAVLAYPRVRALFAEVTADVRVGDDEVAAYHARNPLR
MAV_4511|M.avium_104 PDVTARLEIGSVAAAVLADPLARALFADVTAAVDVAERELAAYHARNPLR
MSMEG_1362|M.smegmatis_MC2_155 PDTAARLEIGSVAASLLASAHARAVFMRVTASVSVTDADVAAYHARNPLR
Mflv_5103|M.gilvum_PYR-GCK LDEVGLMELGSVAAATLATPHGRAVYASVTAEVQVGADAVSDYFARNPYR
Mvan_1250|M.vanbaalenii_PYR-1 PDAVARMEVGSVAAATLADRRGRAVFAAVTGDVRVPEAAVADYHERNPLR
* .. :*:*****: ** **:: **. * * :: *. *** *
Mb0668|M.bovis_AF2122/97 FAA-PCPGQHGWRAPAAAAPPLDQVRRAITEHLLGAARRRAFRVWLDARR
Rv0649|M.tuberculosis_H37Rv FAA-PCPGQHGWRAPAAAAPPLDQVRRAITEHLLGAARRRAFRVWLDARR
MMAR_0986|M.marinum_M FAA-PVPGRHGWHVPPVAAPPLERVRDAIAEHLLGAARRRAFRVWLDGRR
MUL_0738|M.ulcerans_Agy99 FAA-PVPGRHGWHVPPVAAPPLERVRDAIAEHLLGAARRRAFRVWLDGRR
MAV_4511|M.avium_104 FAP-SQPVQNVWRTTALVAPPLDEVRPAIREQLRGAARRRAFRLWLDERR
MSMEG_1362|M.smegmatis_MC2_155 FAPRPDVDADGWRGRP-VAPPLADVENAVRQHLLAAARRREFRRWLDESC
Mflv_5103|M.gilvum_PYR-GCK FAH-GAARPGVWRGPS-SPPRFDDVRALIHAHLLAAARRREYRRWLDAQC
Mvan_1250|M.vanbaalenii_PYR-1 FSS-FRHKVGGWRRAP-GPAHLDEVRAEISAHLLAAARRREYRRWLDARC
*: *: . .. : *. : :* .***** :* ***
Mb0668|M.bovis_AF2122/97 NALVVLAPGYEHPGDPRQPDNTRRH
Rv0649|M.tuberculosis_H37Rv NALVVLAPGYEHPGDPRQPDNTRRH
MMAR_0986|M.marinum_M AALVQLAPGYEHPGDPRQPDNTHRH
MUL_0738|M.ulcerans_Agy99 AALVQLAPGYEHPGDPRQPDNTHRH
MAV_4511|M.avium_104 AALVRLAPGYEHPGDPRQPDNTHRH
MSMEG_1362|M.smegmatis_MC2_155 AKLVGLAPGYEHPGDPRQPDNTHRH
Mflv_5103|M.gilvum_PYR-GCK AALVTLADGYEHPGDPRQPDNTHRH
Mvan_1250|M.vanbaalenii_PYR-1 AELVTLAPGYEHPGDPRQPDNTHRH
** ** **************:**