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TSADHYRTWDAAYVLGALSTDDRREYEGHLSGCGGCRSAVAELDGMPGLLSLLDLDEVIALDHEQPAPPL RPEVLTSVIDRMGARRRRARRATVWAVAVAAALLALAIVLAVRPAIFGSDGGGEQTAPMQNMAKVSETPI NASIALTGYGWGTRIDMACSYGDWGQNPRGTPPQNLGMVVIGHDGSRSQIATWLGLSGATALPSGTTPMQ VDEIRAVQLVSASDGEVLLEKQW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5018 | - | - | 100% (234) | putative transmembrane anti-sigma factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0757 | - | 4e-44 | 42.80% (236) | hypothetical protein Mb0757 |
| M. tuberculosis H37Rv | Rv0736 | - | 4e-44 | 42.80% (236) | hypothetical protein Rv0736 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2164 | - | 2e-29 | 36.29% (237) | hypothetical protein MAB_2164 |
| M. marinum M | MMAR_1074 | - | 2e-42 | 41.42% (239) | hypothetical protein MMAR_1074 |
| M. avium 104 | MAV_4430 | - | 9e-48 | 43.42% (228) | hypothetical protein MAV_4430 |
| M. smegmatis MC2 155 | MSMEG_1487 | - | 5e-83 | 66.09% (230) | hypothetical protein MSMEG_1487 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0832 | - | 2e-42 | 41.00% (239) | hypothetical protein MUL_0832 |
| M. vanbaalenii PYR-1 | Mvan_1351 | - | 8e-96 | 76.96% (230) | putative transmembrane anti-sigma factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5018|M.gilvum_PYR-GCK ---MTS--------------------ADHYRTWDAAYVLGALSTDDRREY
Mvan_1351|M.vanbaalenii_PYR-1 ---MTPQDRQ----------------DDRYRTWDAAYVLGALAGDDRREY
MSMEG_1487|M.smegmatis_MC2_155 ---MTQSEPHRIGPVD----------PDRYSTWDAAYVLGSLSSEERREY
MMAR_1074|M.marinum_M MDDIRTPVTGLGAPTEG---------EHPYLMWDAAYVLGSLSAADRREF
MUL_0832|M.ulcerans_Agy99 MDDIRTPVTGLGAPTEG---------EHPYLMWDAAYVLGSLSAADRREF
MAV_4430|M.avium_104 MDEMRTPVHDVGPP------------EDRYAMWDAAYVLGSLSAAQRREF
Mb0757|M.bovis_AF2122/97 ---MTMPLRGLGPPDDTGVREVSTGDDHHYAMWDAAYVLGALSAADRREF
Rv0736|M.tuberculosis_H37Rv ---MTMPLRGLGPPDDTGVREVSTGDDHHYAMWDAAYVLGALSAADRREF
MAB_2164|M.abscessus_ATCC_1997 -----------------------MTIEHVYADWDAAYVLGALSSTERREY
. * ********:*: :***:
Mflv_5018|M.gilvum_PYR-GCK EGHLSGCGGCRSAVAELDGMPGLLSLLDLDEVIALDHEQPAP-------P
Mvan_1351|M.vanbaalenii_PYR-1 EAHLTGCDRCHSAVAELSGIPGLLAMLDLDEVSALDDAQPDP-------P
MSMEG_1487|M.smegmatis_MC2_155 EAHLTTCPQCRAGVAELSGMPALLSLIDLDDVRAIDGEQPDP-------P
MMAR_1074|M.marinum_M EAHLAGCASCRAAVAELCGVPALLSQLGADEVAAIGEPGVAAGTTSGSPQ
MUL_0832|M.ulcerans_Agy99 EAHLAGCASCRAAVAELCGVPAVLSQLGADEVAAIGEPGVAAGTTSGSPQ
MAV_4430|M.avium_104 EQHMAHCRGCREAVADISGVPALLSRLDHDEVAAIDEAGPAP-------Q
Mb0757|M.bovis_AF2122/97 EAHLAGCPECRGAVTELCGVPALLSQLDRDEVAAISESAPTVVAS----G
Rv0736|M.tuberculosis_H37Rv EAHLAGCPECRGAVTELCGVPALLSQLDRDEVAAISESAPTVVAS----G
MAB_2164|M.abscessus_ATCC_1997 EQHLVDCVSCQRALSEVTAMPGLLSKVDRGYAEKMELEDPPVLAK----P
* *: * *: .:::: .:*.:*: :. . . :
Mflv_5018|M.gilvum_PYR-GCK LRPEVLTSVIDRMGARRRR---ARRATVWAVAVAAALLALAIVLAVRPAI
Mvan_1351|M.vanbaalenii_PYR-1 LRPEVLTSVLDRVSARRRR---ARWWTTTALAAAAVLLAVALVLAIRPAT
MSMEG_1487|M.smegmatis_MC2_155 LRPEVLDSVMAEVGARRRR---TRWLTTSVAALAAVLLAVGIVVLARPEA
MMAR_1074|M.marinum_M MSSQLLPTLLATVRWRRRR---TRLAIWVASSAAAVFLGIGVLVGVV---
MUL_0832|M.ulcerans_Agy99 MSSQLLPTLLATVRWRRRR---TRLAIWVALSAAAVFLGIGVLVGAV---
MAV_4430|M.avium_104 LSADLLPSLLTAVRRRRRR---GRVATWVASAAAAAVLAIGVFVGLE---
Mb0757|M.bovis_AF2122/97 LSPELLPSLLAAVHRRRRR---TRLITWVASSAAAAVLAIGVLVGVQ---
Rv0736|M.tuberculosis_H37Rv LSPELLPSLLAAVHRRRRR---TRLITWVASSAAAAVLAIGVLVGVQ---
MAB_2164|M.abscessus_ATCC_1997 ATSCPVQALWPKLQARWRRQSAVRRLAYVGAVAVAAAVALTVSLVPPPWY
. : :: : * ** * .*. :.: : :
Mflv_5018|M.gilvum_PYR-GCK F----GSDGGGEQ--TAPMQNMAKVSETPINASIALTGYGWGTRIDMACS
Mvan_1351|M.vanbaalenii_PYR-1 F----GLGTGTESPPTAQMQEMAKVSETPINASIALTGYGWGTRIDMACS
MSMEG_1487|M.smegmatis_MC2_155 F----GLQRGTEQQ-TAQMLEMSKVAQTPINASIALTGYTWGTRIDMACS
MMAR_1074|M.marinum_M -----GHSAS-APVQTASAQPMAQVGTHLLESTVSVDGMHWGTFINLRCV
MUL_0832|M.ulcerans_Agy99 -----GHSAS-APVQTASAQPMAQVGTHLLESTVSVDGIHWGTFINLRCV
MAV_4430|M.avium_104 -----GWSSTPARQVTASAEPMAQVGTTLLTSTVQVSGQHWGTSINLRCV
Mb0757|M.bovis_AF2122/97 -----GHSAA-PQRAAVSALPMAQVGTQLLASTVSISGEPWGTFINLRCV
Rv0736|M.tuberculosis_H37Rv -----GHSAA-PQRAAVSALPMAQVGTQLLASTVSISGEPWGTFINLRCV
MAB_2164|M.abscessus_ATCC_1997 HRPAPMNVAAGSLPAGEHWQPMRQVTPSPLSAQVALVRDGTGTRIEMWCS
* :* : : : : ** *:: *
Mflv_5018|M.gilvum_PYR-GCK YGDWGQNPRGTPPQNLGMVVIGHDGSRSQIATWLGLSGATALPSGTTPMQ
Mvan_1351|M.vanbaalenii_PYR-1 YGDWGR--RDAPPQNLGMVVIGDDGSRSEIATWLGLSGATALPSGTTPMP
MSMEG_1487|M.smegmatis_MC2_155 YGDWGS--KGAQPQDLGMVVVGRDGSREQVATWLGLSGATALPSGNTQKP
MMAR_1074|M.marinum_M C----LAPPDAHHDTLAMVVVGRDGSQTRLATWVAEPGHTATPAGSISMP
MUL_0832|M.ulcerans_Agy99 C----LAPPDAHHDTLAMVVVGRDGSQTRLATWVAEPGHTATPAGSISMP
MAV_4430|M.avium_104 C----LAPLNAHHDTLAMVVVGRDGSRTRLATWVAVPGHTASPAGSISTP
Mb0757|M.bovis_AF2122/97 C----LAPPYASHDTLAMVVVGRDGSQTRLATWLAEPGHTATPAGSISTP
Rv0736|M.tuberculosis_H37Rv C----LAPPYASHDTLAMVVVGRDGSQTRLATWLAEPGHTATPAGSISTP
MAB_2164|M.abscessus_ATCC_1997 YPVYGDDADDSAAAPYALRIGTRTGQSIIASSWTAKPGSTLMTSTTVPMA
: .: : *. ::* . .* * .: .
Mflv_5018|M.gilvum_PYR-GCK VDEIRAVQLVS---ASDGEVLLEKQW
Mvan_1351|M.vanbaalenii_PYR-1 LDQIAAVQLVS---SPDGKVLLEKNL
MSMEG_1487|M.smegmatis_MC2_155 MDDIAAIQMVS---VADGKVLLEKKL
MMAR_1074|M.marinum_M VDQIAAVQVVS---ADSGEVLLQRSL
MUL_0832|M.ulcerans_Agy99 VDQIAAVQVVS---ADSGEVLLQRSL
MAV_4430|M.avium_104 VDQIAAVQVVA---ADSGQVLLQRSL
Mb0757|M.bovis_AF2122/97 VDQIAAVQVVA---ADTGQVLLQRSL
Rv0736|M.tuberculosis_H37Rv VDQIAAVQVVA---ADTGQVLLQRSL
MAB_2164|M.abscessus_ATCC_1997 QDQIESIQVIDNHGDASPLVFLELHR
*:* ::*:: *:*: