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MAADIVPIGLTLTKGDVYTLWAPRWRADGDEWEAFLGKDEDLYVLESVADLAAFVRTNNDNDLVDHPAWT KLTEANAHRLTPTESNTHDLVVLEELLAQKPTEAGVSALYGALAVVSSMGSVCELPAVTKFFNGNPVLGT VGGGVEAFAGRAGKKRWAEIEKIIAKGWDKVIEALDEIITIPEVDSAAVAKAQAELDADAPEPDEELVID DVVDTPEESDDLAAEAETKVLGSDKDFWERVGIDPIRIMMTGETYFTLRCYFDDRPIFLGRNGRISVFPS ERALARYLADEHDHDLSDLATYDDIRTAATDGSLRVDVTDDNVYVLTDIVDDLAEGPDALDHDQIELAVE LLRDIGDYSEEATVDTKLAPDTALGRVIFHVLEPGKVARPNAPFADAVTQWESLERFVESRLRSET
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4840 | - | - | 100% (416) | hypothetical protein Mflv_4840 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3339 | - | 1e-155 | 64.85% (421) | hypothetical protein Mb3339 |
| M. tuberculosis H37Rv | Rv3311 | - | 1e-155 | 64.85% (421) | hypothetical protein Rv3311 |
| M. leprae Br4923 | MLBr_00703 | - | 1e-154 | 62.74% (424) | hypothetical protein MLBr_00703 |
| M. abscessus ATCC 19977 | MAB_3669 | - | 1e-144 | 57.47% (442) | hypothetical protein MAB_3669 |
| M. marinum M | MMAR_1215 | - | 1e-157 | 61.68% (441) | hypothetical protein MMAR_1215 |
| M. avium 104 | MAV_4288 | - | 1e-159 | 63.10% (439) | hypothetical protein MAV_4288 |
| M. smegmatis MC2 155 | MSMEG_1684 | - | 1e-165 | 66.13% (431) | hypothetical protein MSMEG_1684 |
| M. thermoresistible (build 8) | TH_1645 | - | 1e-168 | 66.43% (426) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2677 | - | 1e-157 | 62.36% (441) | hypothetical protein MUL_2677 |
| M. vanbaalenii PYR-1 | Mvan_1593 | - | 0.0 | 86.27% (415) | hypothetical protein Mvan_1593 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4840|M.gilvum_PYR-GCK -------------MAADIVPIGLTLTKGDVYTLWAPRWRADGDEWEAFLG
Mvan_1593|M.vanbaalenii_PYR-1 MVGRSGSVIRLCRMAADIVPIGLTLTKGDVYTLWAPRWRADGDEWEAFLG
MSMEG_1684|M.smegmatis_MC2_155 -------------MAADIVPVRLGLTKGDLYTLWAPRWRDAGDEWEAFLG
TH_1645|M.thermoresistible__bu -------------MAADIVPLRIGLTKGDLYTLWAPRWRAAGDEWEAFLG
MLBr_00703|M.leprae_Br4923 -------------MVADLVPICLSLPAGDRYTVWAPRWRDGGDEWEAFLG
MAV_4288|M.avium_104 -------------MAADLVPIRLSLSAGDRYTVWAPRWRDSGDEWEAFLG
Mb3339|M.bovis_AF2122/97 -------------MVADLVPIRLSLSAGDRYTLWAPRWRDAGDEWEAFLG
Rv3311|M.tuberculosis_H37Rv -------------MVADLVPIRLSLSAGDRYTLWAPRWRDAGDEWEAFLG
MMAR_1215|M.marinum_M -------------MAADLVPIRLSLSDGDHYTLWAPRWRDSGDEWEAFLG
MUL_2677|M.ulcerans_Agy99 -------------MAADLVPIRLSLSDGDHYTLWAPRWRDSGDEWEAFLG
MAB_3669|M.abscessus_ATCC_1997 -------------MAADIVPIELGLTEGDVVTLWAPRWRDAGDEWEAFLG
*.**:**: : *. ** *:****** *********
Mflv_4840|M.gilvum_PYR-GCK KDEDLYVLESVADLAAFVRTNNDNDLVDHPAWTKLTEANAHRLTPTESNT
Mvan_1593|M.vanbaalenii_PYR-1 KDEDLYVLESVADLAAFVRTNNDNDLADHPAWQKLTEANAHRLAPSEANT
MSMEG_1684|M.smegmatis_MC2_155 KDEDLFAFETVADLVAFVRTNSDNDLTDHPAWEKLTEANAHKLDPAEDRH
TH_1645|M.thermoresistible__bu KDEDLYAFESVADLVAFVRTDNDNDLTDHPAWQKLTERSAHRLNPGEDGQ
MLBr_00703|M.leprae_Br4923 KDDNLYACETVADLVAFVRTDSDNDLVDHPAWKDLTSVHAHKLDPSEDNQ
MAV_4288|M.avium_104 KDEDLYVFSSVADLVAFVRSDEDNDLTDHPAWTRLRTAHAHKFEPAKDKQ
Mb3339|M.bovis_AF2122/97 KDDDLYGFESVSDLVAFVRTDTENDLVDHPAWQDLTGAHAHNLNPAEDNQ
Rv3311|M.tuberculosis_H37Rv KDDDLYGFESVSDLVAFVRTDTENDLVDHPAWQDLTGAHAHNLNPAEDNQ
MMAR_1215|M.marinum_M KDEDLYVFDSVADLVAFVRTDTDNDLVDHPGWQDLTEAHAHNFDPADDKK
MUL_2677|M.ulcerans_Agy99 KDEDLYVFDSVADLVAFVRTDTDNDLVDHPGWQDLTEAHAHNFDPADDKK
MAB_3669|M.abscessus_ATCC_1997 KDDDLYVFESVADLVAFVRTDNDNDLVDHPAWSTLASLSADELEPDDDNR
**::*: .:*:**.****:: :***.***.* * *..: * .
Mflv_4840|M.gilvum_PYR-GCK HDLVVLEELLAQKPTEAGVSALYGALAVVSSMGSVCELPAVTKFFNGNPV
Mvan_1593|M.vanbaalenii_PYR-1 HDLVVLEELLARKPTEDSVRALHGALAVVSSMGSVCELPAVTKFFNGHPV
MSMEG_1684|M.smegmatis_MC2_155 YDLVGVPEVVAEKPTEDSVEALRRTLAIAASIGSVCDLAAVNRFFNGNPV
TH_1645|M.thermoresistible__bu ADLIGVPELVAEKPTEESVAALRRTLAIASAIGSVCELPAVTKFFNGNPV
MLBr_00703|M.leprae_Br4923 FDLVVVEELVAEKPTAESVTTLAATLAIVASIGSVCELPAVSKFFNGNPS
MAV_4288|M.avium_104 FDLVAVEELVSEKPTEESVTALAGVLAIVSSIGSVCELAAVSKFFNGNPA
Mb3339|M.bovis_AF2122/97 FDLVVVEELLAEKPTAESVAALAASLAIVSAIGSVCELAAVSKFFNGNPI
Rv3311|M.tuberculosis_H37Rv FDLVVVEELLAEKPTAESVAALAASLAIVSAIGSVCELAAVSKFFNGNPI
MMAR_1215|M.marinum_M FDLVIVEELVAEKPTEESVNAMAATLAIVSSIGSVCELTAVSKFFNGNPT
MUL_2677|M.ulcerans_Agy99 FDLVIVEELVAEKPTEESVNAMAATLAIVSSIGSVCELTAVSKFFNGNPT
MAB_3669|M.abscessus_ATCC_1997 YDLIGVPELVADKPTEDAVDTLRATLAIVASIGAVCELAPINKLINGNPV
**: : *::: *** .* :: **:.:::*:**:*..:.:::**:*
Mflv_4840|M.gilvum_PYR-GCK LGTVGGGVEAFAGRAGKKRWAEIEKIIAKGWDKVIEALDEIITIPE-VDS
Mvan_1593|M.vanbaalenii_PYR-1 LGAVGGGVEAFAGRAGRKRWAEIEKIVAKGWDNVIAALDEVITIPD-VDS
MSMEG_1684|M.smegmatis_MC2_155 LSTVGGGIEAFSGRSGRKRWGEIETVILRGWDGVVDAIDEIVAIPEDIDA
TH_1645|M.thermoresistible__bu LSLVGGGVEAFKGRSGRKRWAEISNVIARGWDTVIDAIDEIVSIPP-VDA
MLBr_00703|M.leprae_Br4923 LGAVSGGIEHFTGRAGQRRWNSIAEIIGRSWDDVLSAIDKVISTPR-VNA
MAV_4288|M.avium_104 LGTVSGGIEHFTGKAGAKRWHAIAEIIARGWDDVLGAIDDIATTPE-VEE
Mb3339|M.bovis_AF2122/97 LGTVSGGLEHFTGKAGNKRWNSIAEVIGRSWDDVLAAIDEIISTPE-VDA
Rv3311|M.tuberculosis_H37Rv LGTVSGGLEHFTGKAGNKRWNSIAEVIGRSWDDVLAAIDEIISTPE-VDA
MMAR_1215|M.marinum_M LGTVSGGIDYFSGKAGQKRWNAIAEIIARSWDDVLKAIEEVVSTPE-VDE
MUL_2677|M.ulcerans_Agy99 LGTVSGGIDYFSGKAGQKRWNAIAEIIARSWDDVLKAIEEVVSTPE-VDE
MAB_3669|M.abscessus_ATCC_1997 LGTLSGGAESFTGKDGLKRWNQIGTIVGKSWDSVIDAIDEIAATPD-VDE
*. :.** : * *: * :** * :: :.** *: *::.: : * ::
Mflv_4840|M.gilvum_PYR-GCK AAVAKAQAELDADAPEPD-----------EELVIDDVVDTPE--------
Mvan_1593|M.vanbaalenii_PYR-1 VAAEKAQAELDEPAPEPD-----------EDLVIDDVVDTEE--------
MSMEG_1684|M.smegmatis_MC2_155 AAVKKAEAELDEPAPEEDDED--IAVEDTEDAEADTEADTDE--------
TH_1645|M.thermoresistible__bu AASEKAAAELQEPDPEPD------ADADVDSALEEATAADPD--------
MLBr_00703|M.leprae_Br4923 AMSAKAADELAEEPVEPEVEP-----DDEDGADSATAQANN---------
MAV_4288|M.avium_104 ALSAKAEDELAEERDDEETDE-----ADEAAEAPADATEPDEEALENDEA
Mb3339|M.bovis_AF2122/97 ELSEKVAEELAEEPEG----------AEEVAAEVEATQDTQE--------
Rv3311|M.tuberculosis_H37Rv ELSEKVAEELAEEPEG----------AEEVAAEVEATQDTQE--------
MMAR_1215|M.marinum_M KLSAKAAEELEEEPEEPEEDEGAAGEDDEASADSADEDDEDE--------
MUL_2677|M.ulcerans_Agy99 KLSAKAAEELEEEPEEPEEDEGAAGEDDDASADSADEDDEDE--------
MAB_3669|M.abscessus_ATCC_1997 ELSAAADAELLAAAENAVDKDDDLEDDDELDLLDEDSDSDDE--------
. **
Mflv_4840|M.gilvum_PYR-GCK ----ESDD-------------LAAEAETKVLGSDKDFWERVGIDPIRIMM
Mvan_1593|M.vanbaalenii_PYR-1 ----EADE-------------LAVEAETKVLGSDKDFWARVGIDPVRIMT
MSMEG_1684|M.smegmatis_MC2_155 ----SDDDDDDAV-------VAPATAGTGVLGGDEDFWLKVGIDPVRIMT
TH_1645|M.thermoresistible__bu ----SAAEPEEAS-------ALAGQAQSVVLGSDEDFWLKVGIDPVQILT
MLBr_00703|M.leprae_Br4923 -----SDDTEDE---------SRTAGDTVVLGSDKDFWLQVGIDPVRIMT
MAV_4288|M.avium_104 DGEPDDDADETE---------TRAAGDTVVLGGDKDFWLQVGIDPIRIIT
Mb3339|M.bovis_AF2122/97 --AAESDDEEAD-----------APGDSVVLGGDRDFWLQVGIDPIQIMT
Rv3311|M.tuberculosis_H37Rv --AAESDDEEAD-----------APGDSVVLGGDRDFWLQVGIDPIQIMT
MMAR_1215|M.marinum_M --AAEDEADEDEEDEEDSVEEDRAAGDTVVLGGDEDFWLKVGIDPIRIMT
MUL_2677|M.ulcerans_Agy99 --AAEDEDEEDEEDEEDSVEEDRAAGDTVVLGGDEDFWLKVGIDPIRIMT
MAB_3669|M.abscessus_ATCC_1997 -SSDDAEDESDDAAEDDDTEDEDTADDDVVLGGDEDFWLEVGIDPIQMIT
***.*.*** .*****::::
Mflv_4840|M.gilvum_PYR-GCK TGETYFTLRCYFDDRPIFLGRNGRISVFPSERALARYLADEHDHDLSDLA
Mvan_1593|M.vanbaalenii_PYR-1 SGGTFFTLRCYLDDQPIFLGRNGRISVFTSERALARYLADEHDHDLSGLA
MSMEG_1684|M.smegmatis_MC2_155 GTGTFYTLRCYLDDQPVFLGRNGRISVFPSERTLARYLADEHDHDLSDLA
TH_1645|M.thermoresistible__bu RSGSFFTLRCYLDEAPVFLGRNGRISVFGSERALARYLADEHDHDLSDLA
MLBr_00703|M.leprae_Br4923 GAGTFYTLRCYLDDHPIFLGRNGRISVFSSERALARYLADEHDHDLSYLS
MAV_4288|M.avium_104 SSGTFYTLRCYLDDQPIFLGRNGRISVFTSERALARYLADEHDHDLADLS
Mb3339|M.bovis_AF2122/97 GTATFYTLRCYLDDRPIFLGRNGRISVFGSERALARYLADEHDHDLSDLS
Rv3311|M.tuberculosis_H37Rv GTATFYTLRCYLDDRPIFLGRNGRISVFGSERALARYLADEHDHDLSDLS
MMAR_1215|M.marinum_M GAGNLYTLRCYLDDRPIFLGRNGRISVFSSERALARYLADEHDHDLSDLA
MUL_2677|M.ulcerans_Agy99 GAGNLYTLRCYLDDRPIFLGRNGRISVFSSERALARYLADEHDHDLSDLA
MAB_3669|M.abscessus_ATCC_1997 NSGTFYTLRCYLNDEPIFLGRNGRISVFGSERALARYLADEHDHDLADLS
. :*****::: *:*********** ***:*************: *:
Mflv_4840|M.gilvum_PYR-GCK TYDDIRTAATDGSLRVDVTDDNVYVLTDIVDDLAEGPDALDHDQIELAVE
Mvan_1593|M.vanbaalenii_PYR-1 TYDDIRTAATDGSLRIDVTDDNVYVLTGIVDDLAEGPDALDHDQLELAVE
MSMEG_1684|M.smegmatis_MC2_155 TYDDIRTAATDGSLRVEVTDENVYVLSGIADDIADGPEAIDRDQLELAVE
TH_1645|M.thermoresistible__bu TYDDIRTAATDGSLEIDVTDDNVYVLSGLADDIGDGPDAVDRDQLELAVE
MLBr_00703|M.leprae_Br4923 TYDDIRTAATDGSLAIDITDDNIYVLSGLSDDLADGPDAVDRDQLDLAVE
MAV_4288|M.avium_104 TYDDIRTAATDGSLEVEITDDNIYVLSGLADDLADGPDAVDRDQLELAVE
Mb3339|M.bovis_AF2122/97 TYDDIRTAATDGSLAVAVTDDNVYVLSGLVDDFADGPDAVDREQLDLAVE
Rv3311|M.tuberculosis_H37Rv TYDDIRTAATDGSLAVAVTDDNVYVLSGLVDDFADGPDAVDREQLDLAVE
MMAR_1215|M.marinum_M TYDDIRTAATDGSLAVDVTDENIYVLTGLADDFADGPEAVDHDQLDLAVE
MUL_2677|M.ulcerans_Agy99 TYDDIRTAATDGSLAVDVTDENIYVLTGLADDFADGPEAVDHDQLDLAVE
MAB_3669|M.abscessus_ATCC_1997 TYDDIRTAATDGSLRIDITDDNIYVFTGLADDLEDGVDEVDRDQLELAVE
************** : :**:*:**::.: **: :* : :*::*::****
Mflv_4840|M.gilvum_PYR-GCK LLRDIGDYSEEATVDTKLAPDTALGRVIFHVLEPGKVARPNAPFADAVTQ
Mvan_1593|M.vanbaalenii_PYR-1 LLRDIGDYSEDTGVEAKLAPDTALGRVIAHVLDPKAVKRPGAPYADAVAQ
MSMEG_1684|M.smegmatis_MC2_155 LLRDVSDYSEDKTVDETLSTDQPLGAFVAHVLEPDDHDAPDAPYAKAVEQ
TH_1645|M.thermoresistible__bu LLRDVGEYAEDKIVENTLKPDTALGRFVGHVLTPDKVRKPRGSYAEAVQQ
MLBr_00703|M.leprae_Br4923 LLRDIGQYSEESAVDTALETNRPLGKLVAHVLSPSAVDKPVAPYSAAVRE
MAV_4288|M.avium_104 VLRDIGDYSEDSTVDKALEPGRPLGKLVAAVLEPGSVAKPSPPYAAAVRE
Mb3339|M.bovis_AF2122/97 LLRDIGDYSEDSAVDKALETTRPLGQLVAYVLDPHSVGKPTAPYAAAVRE
Rv3311|M.tuberculosis_H37Rv LLRDIGDYSEDSAVDKALETTRPLGQLVAYVLDPHSVGKPTAPYAAAVRE
MMAR_1215|M.marinum_M LLRDIGDYSEEGTVDKALNPAKPLGKLVAYVLDPDSGSKPAAPYAKAVRE
MUL_2677|M.ulcerans_Agy99 LLRDIGDYSEEGTVDKALNPAKPLGKLVAYVLDPDSGSKPAAPYAKAVRE
MAB_3669|M.abscessus_ATCC_1997 LLTDVAEYSEDDSVDAELDSDTPLGKLVGHLLEPEKHDEPKGPFVDAAER
:* *:.:*:*: *: * . .** .: :* * * .: *. .
Mflv_4840|M.gilvum_PYR-GCK WESLERFVESRLRSET
Mvan_1593|M.vanbaalenii_PYR-1 WESVESFVESRLRQE-
MSMEG_1684|M.smegmatis_MC2_155 WESLVRFVESRLRQE-
TH_1645|M.thermoresistible__bu WEKLEAFVESRLRPE-
MLBr_00703|M.leprae_Br4923 WEKLEQFVESRLRLE-
MAV_4288|M.avium_104 WEKLEQFVDGRLRRE-
Mb3339|M.bovis_AF2122/97 WEKLERFVESRLRRE-
Rv3311|M.tuberculosis_H37Rv WEKLERFVESRLRRE-
MMAR_1215|M.marinum_M WEQLERFVESRLRRE-
MUL_2677|M.ulcerans_Agy99 WEQLERFVESRLRRE-
MAB_3669|M.abscessus_ATCC_1997 WRTLERAMEARLRRE-
*. : ::.*** *