For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
DSGDKAWGNLASKFPGGQMADVASHSNGQRLSPQSVELRVAAALENLAVLRTLVAAIGTFEDLDFDAVAD LRLAVDEACTRLIRSALPDSTLLVVVDPQPDALVVHASTTCDSTDILAPGSFSWHVLSSLTDEVTTFSDG QAADDGEVFGISMTTRRASSLQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4790 | - | - | 100% (163) | putative anti-sigma regulatory factor, serine/threonine protein kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3315c | rsbW | 3e-48 | 66.43% (143) | anti-sigma factor rsbW (sigma negative effector) |
| M. tuberculosis H37Rv | Rv3287c | rsbW | 3e-48 | 66.43% (143) | anti-sigma factor rsbW (sigma negative effector) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2513c | - | 1e-28 | 46.43% (140) | anti-sigma factor RsbW |
| M. marinum M | MMAR_1247 | rsbW | 7e-50 | 61.25% (160) | anti-sigma factor RsbW |
| M. avium 104 | MAV_4258 | - | 3e-49 | 67.13% (143) | RsbW protein |
| M. smegmatis MC2 155 | MSMEG_1803 | - | 8e-49 | 71.32% (129) | RsbW protein |
| M. thermoresistible (build 8) | TH_0240 | rsbW | 1e-43 | 75.44% (114) | ANTI-SIGMA FACTOR RSBW (SIGMA NEGATIVE EFFECTOR) |
| M. ulcerans Agy99 | MUL_2641 | rsbW | 2e-44 | 62.94% (143) | anti-sigma factor RsbW |
| M. vanbaalenii PYR-1 | Mvan_1659 | - | 1e-76 | 87.73% (163) | putative anti-sigma regulatory factor, serine/threonine protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3315c|M.bovis_AF2122/97 ---------------------------MADSDLPTKGRQRGVRAVELNVA
Rv3287c|M.tuberculosis_H37Rv ---------------------------MADSDLPTKGRQRGVRAVELNVA
MMAR_1247|M.marinum_M MTNRLQRWAQSGTQSESTVGAKLPGGQMTDADPRINKRERGHRAVELNVA
MUL_2641|M.ulcerans_Agy99 ---------------------------MTDADPRINKRERGHRAVELNVA
MAV_4258|M.avium_104 ---------------------------MKDAGLHADKRPRGHRAVELHVA
Mflv_4790|M.gilvum_PYR-GCK --------MDSGDKAWGNLASKFPGGQMADVASHSNGQRLSPQSVELRVA
Mvan_1659|M.vanbaalenii_PYR-1 --------MDNGRSGWGNLAGKLLGGQMADVASHINGRRQGAQSVELRVA
TH_0240|M.thermoresistible__bu --------------------------------------------------
MSMEG_1803|M.smegmatis_MC2_155 ---------------------------MAETPAR------GERSVEIRVA
MAB_2513c|M.abscessus_ATCC_199 ---------------------------MTEAHTTHSGSHPDDRSLRFDMA
Mb3315c|M.bovis_AF2122/97 ARLENLALLRTLVGAIGTFEDLDFDAVADLRLAVDEVCTRLIRSALPDAT
Rv3287c|M.tuberculosis_H37Rv ARLENLALLRTLVGAIGTFEDLDFDAVADLRLAVDEVCTRLIRSALPDAT
MMAR_1247|M.marinum_M ARLENLSMLRTLVGAIGTFEDLDFDAVADLRLAVDEVCTRLIRSATPDAT
MUL_2641|M.ulcerans_Agy99 ARLENLSMLRTLVGAIGTFEDLDFDAVADLRLAVDEVCTRLIRSATPDAT
MAV_4258|M.avium_104 ARLENLAMLRTLVGAIGTFEDLDFDAVADLRLAVDEVCTRLIRSATPDAT
Mflv_4790|M.gilvum_PYR-GCK AALENLAVLRTLVAAIGTFEDLDFDAVADLRLAVDEACTRLIRSALPDST
Mvan_1659|M.vanbaalenii_PYR-1 ATLENLAVLRTLVAAIGTFEDLDFDAVADLRLAVDEACTRLIRSAVPDST
TH_0240|M.thermoresistible__bu -------VLRTLVAAVGTFEDLDFDAVADLRLAVDEACTRLVRSAVPGAT
MSMEG_1803|M.smegmatis_MC2_155 AMLENLAVVRTVVAAIATFEDLDFDVVADLRLAVDEACTTLIRSAVPDAT
MAB_2513c|M.abscessus_ATCC_199 ARLENLAMMRTVVAAAATVDDLDMDMVADLKLATDEACTRLVRSSVPNAM
::**:*.* .*.:***:* ****:**.**.** *:**: *.:
Mb3315c|M.bovis_AF2122/97 LRLVVDPRKDEVVVEASAACDTHDVVAPGSFSWHVLTALADDVQTFHDGR
Rv3287c|M.tuberculosis_H37Rv LRLVVDPRKDEVVVEASAACDTHDVVAPGSFSWHVLTALADDVQTFHDGR
MMAR_1247|M.marinum_M LTLVVDPRDDELVVQASAACGTHDVVAPGSFSWHVLTSLADDVQTFHDGR
MUL_2641|M.ulcerans_Agy99 LTLVVDPRDDELVVQASAACSTHDVVALGSFSWHVLTSLADDVQTFHDGR
MAV_4258|M.avium_104 LIVVVDPQDDQLVVEASAACDTHDVVAPGSFSWHVLTSLADDVQTFHDGR
Mflv_4790|M.gilvum_PYR-GCK LLVVVDPQPDALVVHASTTCDSTDILAPGSFSWHVLSSLTDEVTTFSDGQ
Mvan_1659|M.vanbaalenii_PYR-1 LLVVVDPQPDALVVHASTTCDSTDILAPGSFSWHVLSSLTDDVKTFSDGR
TH_0240|M.thermoresistible__bu LVVRVHPYDDVVVVEASTTVTETDILSPGSFSWHVLNSLTDEVRTFQDGQ
MSMEG_1803|M.smegmatis_MC2_155 LVLRVDPGPDAVVISTSTVCIGDNVVEPGSFSWHVLSSLTDEVNTFTDGS
MAB_2513c|M.abscessus_ATCC_199 LVVRLDFHLDRLVMAVYSHCQPGDVFPLDSFSWHVLSSLADHVETFERAH
* : :. * :*: . : ::. .*******.:*:*.* ** .
Mb3315c|M.bovis_AF2122/97 QPDVAGSVFGITLTARR--AASSR----
Rv3287c|M.tuberculosis_H37Rv QPDVAGSVFGITLTARR--AASSR----
MMAR_1247|M.marinum_M PPEAAGSVFGIMLTARR--VASGR----
MUL_2641|M.ulcerans_Agy99 PPEAAGSVFGIMLTARR--VASGR----
MAV_4258|M.avium_104 EPNEAGSVFGITLTARR--AASSR----
Mflv_4790|M.gilvum_PYR-GCK AAD-DGEVFGISMTTRR--ASSLQ----
Mvan_1659|M.vanbaalenii_PYR-1 SVG-DGEVFGISMTTRR--ASSLQ----
TH_0240|M.thermoresistible__bu QAS-GAQVCGIAMTTRR--ASSLR----
MSMEG_1803|M.smegmatis_MC2_155 GPE-EGQVFGITMTTRR--ASLLR----
MAB_2513c|M.abscessus_ATCC_199 PDDPVGHIVGISLTKLRDTGSAVRVANG
. : ** :* * : :