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MTYPDPTLFGHDPWWLILAKSLGVFVFLLLTVLAAILIERKILGRMQLRLGPNRVGPRGLLQSLADGIKL ALKEGLVPAGVDKWIYLAAPVISVIPAFMAFAVIPLGPEVSVFGHRTALQLTDLPVAVLYILAVTSIGVY GIVLAGWASGSVYPLLGGLRSSAQVISYEIAMALSFVAVFIYAGTMSTSGIVAAQNDVWFIFLLLPSFLV YLTSMVGETNRAPFDLPEAEGELVGGFHTEYSSLKFAMFMLAEYVNMTTVSALATTLFLGGWHAPWPISI ADGANSDWWPLLWFTAKVWLFLFFFMWLRATLPRMRYDQFMRLGWKLLIPVSLAWIAIVATTRAMQNQGY QGWVTALIGVAGVAAILASLLAWRALRARRRRTSHSPPAQSSDHGAFPVPPLPVKEPADA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4488 | - | - | 100% (410) | NADH dehydrogenase subunit H |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3176 | nuoH | 1e-166 | 70.57% (401) | NADH dehydrogenase subunit H |
| M. tuberculosis H37Rv | Rv3152 | nuoH | 1e-166 | 70.57% (401) | NADH dehydrogenase subunit H |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2141 | - | 1e-164 | 68.90% (418) | NADH dehydrogenase subunit H |
| M. marinum M | MMAR_1476 | nuoH | 1e-169 | 69.66% (412) | NADH dehydrogenase I (chain H) NuoH (NADH- ubiquinone |
| M. avium 104 | MAV_4040 | - | 1e-165 | 70.25% (400) | NADH dehydrogenase subunit H |
| M. smegmatis MC2 155 | MSMEG_2056 | nuoH | 0.0 | 77.97% (413) | NADH dehydrogenase subunit H |
| M. thermoresistible (build 8) | TH_1086 | nuoH | 0.0 | 74.94% (403) | PROBABLE NADH DEHYDROGENASE I (CHAIN H) NUOH |
| M. ulcerans Agy99 | MUL_2466 | nuoH | 1e-169 | 69.66% (412) | NADH dehydrogenase subunit H |
| M. vanbaalenii PYR-1 | Mvan_1878 | - | 0.0 | 85.75% (414) | NADH dehydrogenase subunit H |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4488|M.gilvum_PYR-GCK MT-YPDPTLFGHDPWWLILAKSLGVFVFLLLTVLAAILIERKILGRMQLR
Mvan_1878|M.vanbaalenii_PYR-1 MT-YPDPTLFGHDPWWLVLAKSLGIFAFLLLTVLAAILIERKVLGRMQLR
MSMEG_2056|M.smegmatis_MC2_155 MT-HPDPTLFGHDPWWLMLAKAVAIFVFLLLTVLSAILIERKLLGRMQMR
MAB_2141|M.abscessus_ATCC_1997 MTGRTDLSQFGIDPLWLVLVKCVAVFAFLVLTVLIAILAERRVLAWMQRR
TH_1086|M.thermoresistible__bu VT-YPDPGAFGHDPWWLIVAKTVGIFGFLVLTVLSAILIERKILGRMQMR
Mb3176|M.bovis_AF2122/97 ------MTTFGHDTWWLVAAKAIAVFVFLMLTVLVAILAERKLLGRMQLR
Rv3152|M.tuberculosis_H37Rv ------MTTFGHDTWWLVAAKAIAVFVFLMLTVLVAILAERKLLGRMQLR
MMAR_1476|M.marinum_M ------MTDFGHDVWWLVVAKAIAIFVFLMLTVLVAILAERKLLGRMQLR
MUL_2466|M.ulcerans_Agy99 ------MTDFGHDVWWLVVAKAIAIFVFLMLTVLVAILAERKLLGRMQLR
MAV_4040|M.avium_104 MT--TPLTAFGHDPWWLVLGKALAIFVFLMLNVLVAILLERKILGWMQLR
** * **: * :.:* **:*.** *** **::*. ** *
Mflv_4488|M.gilvum_PYR-GCK LGPNRVGPRGLLQSLADGIKLALKEGLVPAGVDKWIYLAAPVISVIPAFM
Mvan_1878|M.vanbaalenii_PYR-1 FGPNRVGPHGLLQSLADGVKLALKEGLVPAGVDKWIYLAAPIISVIPAFM
MSMEG_2056|M.smegmatis_MC2_155 FGPNRVGPAGLLQSLADGIKLALKEGLVPAGVDKPIYLLAPVISVIPAFV
MAB_2141|M.abscessus_ATCC_1997 IGPNRVGPFGLLQSLADGVKLALKEGLTPAGVDKPIYLLAPIISVVPAIV
TH_1086|M.thermoresistible__bu FGPNRVGPRGLLQSVADGVKLALKEGLIPRAADKPLYLLAPVIAVIPAFM
Mb3176|M.bovis_AF2122/97 PGPNRVGPKGALQSLADGIKLALKESITPGGIDRFVYFVAPIISVIPAFT
Rv3152|M.tuberculosis_H37Rv PGPNRVGPKGALQSLADGIKLALKESITPGGIDRFVYFVAPIISVIPAFT
MMAR_1476|M.marinum_M PGPNRVGPKGSLQSLADGIKLALKESITPGGIDRFVYFVAPIISVIPAFT
MUL_2466|M.ulcerans_Agy99 PGPNRVGPKGSLQSLADGIKLALKESITPGGIDRFVYFVAPIISVIPAFT
MAV_4040|M.avium_104 PGPNRVGPWGVLQSLADGIKLALKETITPGGVDKFVYFAAPVISTIPAFT
******* * ***:***:****** : * . *: :*: **:*:.:**:
Mflv_4488|M.gilvum_PYR-GCK AFAVIPLGPEVSVFGHRTALQLTDLPVAVLYILAVTSIGVYGIVLAGWAS
Mvan_1878|M.vanbaalenii_PYR-1 AFAVIPMGGEVSVFGHRTALQLTDLPVAVLYILAVTSIGVYGIVLAGWAS
MSMEG_2056|M.smegmatis_MC2_155 AFSVIPLGGAVSVFGHRTPLQLTDLPVAVLFILAATSIGVYGIVLAGWAS
MAB_2141|M.abscessus_ATCC_1997 AYAVIPFGPVVSVFGHRTPLQLTDLPVAILFVLAVTSVGVYGIVLGGWAS
TH_1086|M.thermoresistible__bu AFAVIPMGPVVSVFGHRTPLQLTDLPVAVLYILAVASVGVYGFILAGWSS
Mb3176|M.bovis_AF2122/97 AFAFIPFGPEVSVFGHRTPLQITDLPVAVLFILGLSAIGVYGIVLGGWAS
Rv3152|M.tuberculosis_H37Rv AFAFIPFGPEVSVFGHRTPLQITDLPVAVLFILGLSAIGVYGIVLGGWAS
MMAR_1476|M.marinum_M AFAFIPFGPVVSVFGHRTPLQLTDLPVAVLFILGLSAIGVYGIVLGGWAS
MUL_2466|M.ulcerans_Agy99 AFAFIPFGPVVSVFGHRTPLQLTDLPVAVLFILGLSAIGVYGIVLGGWAS
MAV_4040|M.avium_104 AFAFIPFGPVVSVFGHRTPLQLTDLPVAVLFILGLSAIGVYGIVLGGWAS
*::.**:* ********.**:******:*::*. :::****::*.**:*
Mflv_4488|M.gilvum_PYR-GCK GSVYPLLGGLRSSAQVISYEIAMALSFVAVFIYAGTMSTSGIVAAQNDVW
Mvan_1878|M.vanbaalenii_PYR-1 GSVYPLLGGLRSSAQVISYEIAMALSFAAVFIYAGTMSTSGIVAAQNDTW
MSMEG_2056|M.smegmatis_MC2_155 GSTYPLLGGLRSSAQVVSYEIAMGLSFVAVFLYAGTMSTSGIVAAQDRTW
MAB_2141|M.abscessus_ATCC_1997 GSTYPLLGGLRSSAQVISYEIAMGLTFAAVFLLAGTMSTSGIVAAQEGRW
TH_1086|M.thermoresistible__bu GSTYPLLGGLRSTAQVISYEVAMALTFVAVFLYAGTMSTSGIVAAQQGTW
Mb3176|M.bovis_AF2122/97 GSTYPLLGGVRSTAQVISYEVAMGLSFATVFLMAGTMSTSQIVAAQDGVW
Rv3152|M.tuberculosis_H37Rv GSTYPLLGGVRSTAQVISYEVAMGLSFATVFLMAGTMSTSQIVAAQDGVW
MMAR_1476|M.marinum_M GSTYPLLGGVRSTAQVISYEVAMGLSFAAVFLYAGSMSTSQIIAAQDRVW
MUL_2466|M.ulcerans_Agy99 GSTYPLLGGVRSTAQVISYEVAMGLSFAAVFLYAGSMSTSQIIAAQDRVW
MAV_4040|M.avium_104 GSTYPLLGGVRSTAQVISYEVAMGLSFAAVFLYAGSMSTSQIVAAQDRVW
**.******:**:***:***:**.*:*.:**: **:**** *:***: *
Mflv_4488|M.gilvum_PYR-GCK FIFLLLPSFLVYLTSMVGETNRAPFDLPEAEGELVGGFHTEYSSLKFAMF
Mvan_1878|M.vanbaalenii_PYR-1 YIVLLLPSFLVYVTAMVGETNRAPFDLPEAEGELVGGFHTEYSSLKFAMF
MSMEG_2056|M.smegmatis_MC2_155 FVFLLLPSFLVYVVSMVGETNRAPFDLPEAEGELVGGFHTEYSSLKFAMF
MAB_2141|M.abscessus_ATCC_1997 YLFLLLPSFLVYVTAMVGETNRAPFDLPEAEGELVGGFHTEYSSLRFAMF
TH_1086|M.thermoresistible__bu YLFLLLPSFLVFLVAMVGETNRAPFDLPEAEGELVGGFHTEYSSLKFAMF
Mb3176|M.bovis_AF2122/97 YAFLLLPSFVIYLISMVGETNRAPFDLPEAEGELVAGFHTEYSSLKFAMF
Rv3152|M.tuberculosis_H37Rv YAFLLLPSFVIYLISMVGETNRAPFDLPEAEGELVAGFHTEYSSLKFAMF
MMAR_1476|M.marinum_M YIFLLLPSFVIYLISMVGETNRAPFDLPEAEGELVAGFHTEYSSLKFAMF
MUL_2466|M.ulcerans_Agy99 YIFLLLPSFVIYLISMVGETNRAPFDLPEAEGELVAGFHTEYSSLKFAMF
MAV_4040|M.avium_104 FVFLLLPSFVIYLISMVGETNRAPFDLPEAEGELVAGFHTEYSSLKFAMF
: .******:::: :********************.*********:****
Mflv_4488|M.gilvum_PYR-GCK MLAEYVNMTTVSALATTLFLGGWHAPWPISIADGANSDWWPLLWFTAKVW
Mvan_1878|M.vanbaalenii_PYR-1 MLAEYVNMTTVSALATTLFLGGWHAPWPISIADGANSGWWPLLWFTVKVW
MSMEG_2056|M.smegmatis_MC2_155 MLAEYVNMTTVSALATTMFLGGWHAPFPFNLIDGANSGWWPLLWFTAKVW
MAB_2141|M.abscessus_ATCC_1997 MLAEYINMATVSGLAATMFLGGWHAPWPLSLIDGANTSWLPALWFVAKVW
TH_1086|M.thermoresistible__bu MLAEYINMATVSALATTLFLGGWAAPWPINMWAGANSGWWPLLWFTAKVW
Mb3176|M.bovis_AF2122/97 MLAEYVNMTTVSALAATLFFGGWHAPWPLNMWASANTGWWPLIWFTAKVW
Rv3152|M.tuberculosis_H37Rv MLAEYVNMTTVSALAATLFFGGWHAPWPLNMWASANTGWWPLIWFTAKVW
MMAR_1476|M.marinum_M MLAEYVNMTTVSALAATLFLGGWHAPWPLNLWHGANAGWWPVLWFTAKVW
MUL_2466|M.ulcerans_Agy99 MLAEYVNMTTVSALAATLFLGGWHAPWPLNLWHGANAGWWPVLWFTAKVW
MAV_4040|M.avium_104 MLAEYVNMMTVSSLATALFFGGWHAPWPLNMWAGANTGWWPVLWFTAKMW
*****:** ***.**:::*:*** **:*:.: .**:.* * :**..*:*
Mflv_4488|M.gilvum_PYR-GCK LFLFFFMWLRATLPRMRYDQFMRLGWKLLIPVSLAWIAIVATTRAMQNQG
Mvan_1878|M.vanbaalenii_PYR-1 LFLFFFMWLRATLPRMRYDQFMALGWKILIPVSLGWIMIVAITHSLRDQG
MSMEG_2056|M.smegmatis_MC2_155 TFMFLYFWLRATLPRLRYDQFMALGWKVLIPVSLLWIMVVAITRSLRQHG
MAB_2141|M.abscessus_ATCC_1997 GFMFLFMWLRATLPRLRYDQFMRLGWEVLIPVALVWIVVVGVVKAMGLYG
TH_1086|M.thermoresistible__bu VFLFVFFWLRATLPRLRYDQFMALGWKVLIPMSMVWIMVVATARGLQVFG
Mb3176|M.bovis_AF2122/97 GFLFIYFWLRATLPRLRYDQFMALGWKLLIPVSLVWVMVAAIIRSLRNQG
Rv3152|M.tuberculosis_H37Rv GFLFIYFWLRATLPRLRYDQFMALGWKLLIPVSLVWVMVAAIIRSLRNQG
MMAR_1476|M.marinum_M GFLFMYFWLRATLPRLRYDQFMALGWKLLIPVSLVWVLIAAVIRTLRNQG
MUL_2466|M.ulcerans_Agy99 GFLFMYFWLRATLPRLRYDQFMALGWKLLIPVSLVWVLIAAVIRTLRNQG
MAV_4040|M.avium_104 TFLFIYFWLRASLPRLRYDQFMGLGWKLLIPASLVWVLIAAVIRTLQNQG
*:*.::****:***:****** ***::*** :: *: :.. : : *
Mflv_4488|M.gilvum_PYR-GCK YQGWVTALIGVAGVAAILASLLAWRALRARRRRTS---------HSPPAQ
Mvan_1878|M.vanbaalenii_PYR-1 YQAPATAAIGLAVAAVILLALLGRSRLRARRIRP------------EPIR
MSMEG_2056|M.smegmatis_MC2_155 EGTWAAWLLTAAVVVVVALIWGLATSLRRRTVQP------------PPPQ
MAB_2141|M.abscessus_ATCC_1997 YGN-PSIILGITGVAVSLGSIGLVGVLSRRTQPPKP--------VLPARF
TH_1086|M.thermoresistible__bu YVGWSTGLTSVAAITALALIAVVWWVFSRRNEAE------------PALP
Mb3176|M.bovis_AF2122/97 YQYWTPTLVFSSIVVAAAMVLLLRKPLSAPGARASARQRG-------DEG
Rv3152|M.tuberculosis_H37Rv YQYWTPTLVFSSIVVAAAMVLLLRKPLSAPGARASARQRG-------DEG
MMAR_1476|M.marinum_M YQYWTPALVVSSIVVAAILVMSLRKPFSTPNAVTKARRRGKQPAAGPDEQ
MUL_2466|M.ulcerans_Agy99 YQYWTPALVVSSIVVAAILVMSLRKPFSTPNAVTKARRRGKQPAAGPDEQ
MAV_4040|M.avium_104 YAHWTPILVISSIVFAAALVLSLRKPFTTPHIRALRRAAAP------PGQ
. : . :
Mflv_4488|M.gilvum_PYR-GCK SSDHGAFPVPPLPVK-----------EPADA--
Mvan_1878|M.vanbaalenii_PYR-1 PAGDGAFPVPPLPVKTR-------ALEDADA--
MSMEG_2056|M.smegmatis_MC2_155 ST--GAYPVPPLPSVG--------TKETADA--
MAB_2141|M.abscessus_ATCC_1997 DPMAGGFPVPPLPGQRVDTGAHPSTKEDADA--
TH_1086|M.thermoresistible__bu QTHSGAFPVPSLPAGQQRTEN---AKETVDV--
Mb3176|M.bovis_AF2122/97 TSPEPAFPTPPL--------LAGATKENAGG--
Rv3152|M.tuberculosis_H37Rv TSPEPAFPTPPL--------LAGATKENAGG--
MMAR_1476|M.marinum_M GALEPLFPTPPLPMKPL-AQPVGASKENARG--
MUL_2466|M.ulcerans_Agy99 GALEPLFPTPPLPMKPL-AQPVGASKENARG--
MAV_4040|M.avium_104 AAAHRAGFHPGIP-------DTAAAGESAGGRE
. * : * .