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M. gilvum PYR-GCK Mflv_4238 (ilvH)

annotation: acetolactate synthase 3 regulatory subunit
coordinates: 4498198 - 4498698
length: 166

ATTHTLSVLVEDKPGVLARVASLFSRRGYNIQSLAVGATEHKDLSRMTIVVDVEESPLEQITKQLNKLIN
VIKIVEQDEEHSVSRELALIKVRTDATTRGQVIEAVNLFRAKVVDVSTESLTVEATGTPEKIEALLRVLE
PYGVREIVQSGVVSLSRGPRGISTK*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. gilvum PYR-GCK Mflv_4238 ilvH - 100% (166) acetolactate synthase 3 regulatory subunit

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3027c ilvH 3e-70 83.33% (162) acetolactate synthase 3 regulatory subunit
M. tuberculosis H37Rv Rv3002c ilvH 3e-70 83.33% (162) acetolactate synthase 3 regulatory subunit
M. leprae Br4923 MLBr_01695 ilvH 5e-68 80.86% (162) acetolactate synthase 3 regulatory subunit
M. abscessus ATCC 19977 MAB_3322c ilvH 3e-68 78.05% (164) acetolactate synthase 3 regulatory subunit
M. marinum M MMAR_1711 ilvH 5e-70 80.86% (162) acetolactate synthase (small subunit) IlvN
M. avium 104 MAV_3851 ilvH 2e-70 83.95% (162) acetolactate synthase 3 regulatory subunit
M. smegmatis MC2 155 MSMEG_2373 ilvH 1e-76 90.00% (160) acetolactate synthase 3 regulatory subunit
M. thermoresistible (build 8) TH_0063 ilvN 2e-75 87.04% (162) PROBABLE ACETOLACTATE SYNTHASE (SMALL SUBUNIT) ILVN
M. ulcerans Agy99 MUL_1948 ilvH 3e-70 80.86% (162) acetolactate synthase 3 regulatory subunit
M. vanbaalenii PYR-1 Mvan_2123 ilvH 1e-82 95.78% (166) acetolactate synthase 3 regulatory subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4238|M.gilvum_PYR-GCK          -MAT-----THTLSVLVEDKPGVLARVASLFSRRGYNIQSLAVGATEHKD
Mvan_2123|M.vanbaalenii_PYR-1       -MSI-----THTLSVLVEDKPGVLARVASLFSRRGYNIQSLAVGATEHKD
TH_0063|M.thermoresistible__bu      -MSASNSVRTHTLSVLVEDKPGVLARVASLFSRRGFNIQSLAVGATEQKN
MSMEG_2373|M.smegmatis_MC2_155      -MSNG--TPTHTLSVLVEDKPGVLARVSSLFSRRGFNIQSLAVGATEQKD
MAB_3322c|M.abscessus_ATCC_199      -MTS-----THTLSVLVEDRPGVLARVAALFSRRGFNIASLAVGPTELKD
Mb3027c|M.bovis_AF2122/97           -MSPK----THTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATECKD
Rv3002c|M.tuberculosis_H37Rv        -MSPK----THTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATECKD
MMAR_1711|M.marinum_M               -MSTK----THTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATEQKD
MUL_1948|M.ulcerans_Agy99           -MSTK----THTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATEQKD
MAV_3851|M.avium_104                -MSPQ----THTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATEQKD
MLBr_01695|M.leprae_Br4923          MVGLP----THTLSVLVEDTPGVLARVAALFSRRGFNIESLAVGATECKT
                                     :       ********** *******::******:** *****.** * 

Mflv_4238|M.gilvum_PYR-GCK          LSRMTIVVDVEESPLEQITKQLNKLINVIKIVEQDEEHSVSRELALIKVR
Mvan_2123|M.vanbaalenii_PYR-1       LSRMTIVVDVEESPLEQITKQLNKLINVIKIVEQDEENSVSRELALIKVR
TH_0063|M.thermoresistible__bu      LSRMTIVVSVEEAPLEQITKQLNKLVNVIKIVEQDPENSVARELALIKVR
MSMEG_2373|M.smegmatis_MC2_155      MSRMTIVVSVEDSPLEQITKQLNKLINVIKIVEQEEDNSVSRELALIKVR
MAB_3322c|M.abscessus_ATCC_199      VSRMTIVVTVDDFPLEQVTKQLNKLINVIKIVEQDEDNSVARELMLVKVR
Mb3027c|M.bovis_AF2122/97           RSRMTIVVSAEDTPLEQITKQLNKLINVIKIVEQDDEHSVSRELALIKVQ
Rv3002c|M.tuberculosis_H37Rv        RSRMTIVVSAEDTPLEQITKQLNKLINVIKIVEQDDEHSVSRELALIKVQ
MMAR_1711|M.marinum_M               MSRMTIVVSAEATPLEQITKQLNKLINVIKIIEQDDDHSVARELALIKVR
MUL_1948|M.ulcerans_Agy99           MSRMTIVVSAEATPLEQITKQLNKLINVIKIIEQDDDHSVARELALIKVR
MAV_3851|M.avium_104                MSRMTIVVSAEETPLEQITKQLNKLINVIKIVELEDGNSVSRELALIKVR
MLBr_01695|M.leprae_Br4923          MSRMTIVVSAEETPLEQVTKQLHKLINVIKVVEQEADNSLSRELALIKVR
                                     ******* .:  ****:****:**:****::* :  :*::*** *:**:

Mflv_4238|M.gilvum_PYR-GCK          TDATTRGQVIEAVNLFRAKVVDVSTESLTVEATGTPEKIEALLRVLEPYG
Mvan_2123|M.vanbaalenii_PYR-1       TDAATRGQVIEAVNLFRAKVVDVSNESLTVEATGTPGKIEALLRVLEPYG
TH_0063|M.thermoresistible__bu      ADATTRGQIIETVNLFRAKVVDVSTESLTIEATGTQDKLDALLRVLEPYG
MSMEG_2373|M.smegmatis_MC2_155      ADATTRGQIIEAVNLFRAKVVDVSTESLTIEATGTPEKLEALLRVLEPYG
MAB_3322c|M.abscessus_ATCC_199      ADATVRAQVIEVVNLFRAKVVDVSPESVTIEATGTQSKLDALLRMLDPYG
Mb3027c|M.bovis_AF2122/97           ADAGSRSQVIEAVNLFRANVIDVSPESLTVEATGNRGKLEALLRVLEPFG
Rv3002c|M.tuberculosis_H37Rv        ADAGSRSQVIEAVNLFRANVIDVSPESLTVEATGNRGKLEALLRVLEPFG
MMAR_1711|M.marinum_M               ADAGTRSQVIEAVNLFRGKIIDVSPESLTIEATGDRGKLEALLRVLEPFG
MUL_1948|M.ulcerans_Agy99           ADAGTRSQVIEAVNLFRGKIIDVSPESLTIEATGDRGKLEALLRVLEPFG
MAV_3851|M.avium_104                ADAGTRSQVIEAVNLFRAKVIDVSPEALTIEATGDRGKIEALLRVLEPFG
MLBr_01695|M.leprae_Br4923          AEAGTRSQVIEAVHLFRARVIDVSLESLTVEATGDCSKIEALLRVLEPFG
                                    ::*  *.*:**.*:***..::*** *::*:****   *::****:*:*:*

Mflv_4238|M.gilvum_PYR-GCK          VREIVQSGVVSLSRGPRGISTK----
Mvan_2123|M.vanbaalenii_PYR-1       IREIVQSGVVSLSRGPRGISTK----
TH_0063|M.thermoresistible__bu      IRELVQSGIVSLSRGPRGIGTVKQAP
MSMEG_2373|M.smegmatis_MC2_155      IREIAQSGVVSVSRGPRGIGAAK---
MAB_3322c|M.abscessus_ATCC_199      IREIVQSGVVALSRGPRSIAAAK---
Mb3027c|M.bovis_AF2122/97           IREIAQSGMVSLSRGPRGIGTAK---
Rv3002c|M.tuberculosis_H37Rv        IREIAQSGMVSLSRGPRGIGTAK---
MMAR_1711|M.marinum_M               IREIAQSGMVALSRGPRGIGTAAK--
MUL_1948|M.ulcerans_Agy99           IREIAQSGMVALSRGPRGIGTAAK--
MAV_3851|M.avium_104                IREIVQSGVVSLSRGPRGIGTAK---
MLBr_01695|M.leprae_Br4923          VREIVQSGVVSLSRGPRGIGTVR---
                                    :**:.***:*::*****.*.:

species	id	gene	e-value	identity (len)	annotation
M. gilvum PYR-GCK	Mflv_4238	ilvH	-	100% (166)	acetolactate synthase 3 regulatory subunit