For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTLPEGTHDPTTLTNQAPEAIPKHRWRALLVRLHFYAGVLVGPFLVIAALTGALYAMAPTVERVVYRDLL FVEPGDRVLPLDDQVAAARRSYPALTVTGVRPPAAENESVRVYFADPALAPDLGRAVFVDPYTGRVLGDE VTWLGCLPVSTWLDGLHRHLNLGEPGRLYSELAASWLWVVASGGLYLWLVNAAGDRRRGRKPRILTVDRT AGGRSRNLNWHGATGVWLLGGLLFLSATGITWSTYAGAHVSDLRAAFEWQRPQLDTATHGDHGDHAPAAG HTAGPQSVDFDGVLAAATTAGVDLPVEILLPAEHGAAVTVSEIDKPYRWTTDAAAVNPGDLTVTGTVDYW RDYSLIAKLADWGIRGHMGFLFGLLNQLLLLGIAVGLLAVIVRGYRMWWQRRPTRGSRWAVGRPPARGGL RRLRPLTVTALVAGAVTVGWFLPLLGLTLAAFALTDLILGSIKKNASLKKNASLKKNASLNENTENSHVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4207 | - | - | 100% (490) | peptidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3429 | - | 1e-104 | 47.31% (446) | putative integral membrane protein |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_6570 | - | 1e-111 | 46.97% (462) | integral membrane protein |
| M. thermoresistible (build 8) | TH_0807 | - | 1e-106 | 48.57% (453) | integral membrane protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2159 | - | 0.0 | 70.90% (457) | peptidase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6570|M.smegmatis_MC2_155 MTTTPDDRPRTESPPTSPPTAR--AAARQLLMRLHFYAGVFVGPFILIAA
TH_0807|M.thermoresistible__bu --------------------------VLALLRRLHFYAGVFVGPFILIAA
MAB_3429|M.abscessus_ATCC_1997 MTYTED---RPDARESQPDTVW--GRFAPIVLRLHFYAGLLVGPFLLIAA
Mflv_4207|M.gilvum_PYR-GCK MTLPEGTHDPTTLTN-QAPEAIPKHRWRALLVRLHFYAGVLVGPFLVIAA
Mvan_2159|M.vanbaalenii_PYR-1 MPPAENTVQPLPTTDDQPPQTIPKHRWRAMIVRLHFYAGVLVAPFLLVAA
:: *******::*.**:::**
MSMEG_6570|M.smegmatis_MC2_155 VTGLLYALIPQIDATVYRHELTVDHIGQHRLPLTDQIAAARAAHPEGTVA
TH_0807|M.thermoresistible__bu VTGLLYALIPQIDAAVHRHELTVDRVGEQRLPLAEQIAAARAAHPTGAVS
MAB_3429|M.abscessus_ATCC_1997 LTGLAYALVGQVDAAVYRHELKVDSVGPQQLPLSQQVSVATAAQPSGTVT
Mflv_4207|M.gilvum_PYR-GCK LTGALYAMAPTVERVVYRDLLFVE-PGDRVLPLDDQVAAARRSYPALTVT
Mvan_2159|M.vanbaalenii_PYR-1 VTGGLYALAPTLERLVYGDILFVD-VQGSPLPLGDQIAAAQEEFPGLTVS
:** **: :: *: . * *: *** :*::.* * :*:
MSMEG_6570|M.smegmatis_MC2_155 SIRPPAEPTETTQVQLSVD----DVPPDYSRTVFVDPYTAEVRGALTTYG
TH_0807|M.thermoresistible__bu SVRPPVTAEETTQVTFAVDPETSGVPADYARTVFVDPYTGEVRGTLTTYG
MAB_3429|M.abscessus_ATCC_1997 SIRPPANPDDTTRVVLAVP----DVPEDYSRTVFVDPYSGEIRGTLTTYG
Mflv_4207|M.gilvum_PYR-GCK GVRPPAAENESVRVYFADP----ALAPDLGRAVFVDPYTGRVLGDEVTWL
Mvan_2159|M.vanbaalenii_PYR-1 GIRPPAGATESTRVYFVDP----ALDEEKLRTVFVDPYTGRVLGDEPTWF
.:***. ::.:* : : : *:******:..: * *:
MSMEG_6570|M.smegmatis_MC2_155 QWMPIRAWFDDLHRNLHLGAFGRHYSELAASWMWVIALAGLALWLLQR--
TH_0807|M.thermoresistible__bu QWMPVRAWFDELHRNLHLGAVGRHYSELAASWLWVIALAGLVLWVRHR--
MAB_3429|M.abscessus_ATCC_1997 EWLPVRAWFDELHRNLHLGAIGRNYSELAASWLWVVALGGLFLWIGYR--
Mflv_4207|M.gilvum_PYR-GCK GCLPVSTWLDGLHRHLNLGEPGRLYSELAASWLWVVASGGLYLWLVNAAG
Mvan_2159|M.vanbaalenii_PYR-1 GYLPMSTWLDGLHRHLNLGEPGRIYSELAASWLWVVASGGLYLWVLKAAG
:*: :*:* ***:*:** ** ********:**:* .** **:
MSMEG_6570|M.smegmatis_MC2_155 -RDKR--SRLVVPDRAATG-----RRKAMSWHAVIGVWVLAVLLALSVTG
TH_0807|M.thermoresistible__bu -RRSGGLRRLALPDRAGPDGSPNSRNRAVSRHAAVGVWLLVALLGLSATG
MAB_3429|M.abscessus_ATCC_1997 -RRTGRLRRIAVPDRDATP-----RRRRLTWHGAVGVWIVVGLLALSVTG
Mflv_4207|M.gilvum_PYR-GCK DRRRGRKPRILTVDRTAGG-----RSRNLNWHGATGVWLLGGLLFLSATG
Mvan_2159|M.vanbaalenii_PYR-1 DRRRGRTGRLLTVDRSTGG-----RARTLSWHGATGVWLLAGLLFLSATG
* *: ** * : :. *.. ***:: ** **.**
MSMEG_6570|M.smegmatis_MC2_155 ITWSRYGGETISTLQARLNS-TAPSVDASAP----------AHHHGHGTA
TH_0807|M.thermoresistible__bu ITWSRYGGASVDRLQQQLNS-KAPAVDTSLSTPATGQHGHAGHHSGTGSG
MAB_3429|M.abscessus_ATCC_1997 LTWSRYAGTNIGDLTQAIRPGLSTELDPASATPMTG----HEHHGAAATS
Mflv_4207|M.gilvum_PYR-GCK ITWSTYAGAHVSDLRAAFEW-QRPQLDT--ATHGDHG----DHAPAAGHT
Mvan_2159|M.vanbaalenii_PYR-1 ITWSTYAGAHVSDIRSAMNW-QRPQLDSTLAGHGDHG----GHGVPGPAV
:*** *.* :. : :. . :*. . *
MSMEG_6570|M.smegmatis_MC2_155 -PTTLDGADAVLHTAEEVGLKGPMWLYPPAEHGAVWTVSERKRDWPTRND
TH_0807|M.thermoresistible__bu -DELLAGVDTVLRSAQQAGLAGPMWLYPPAEPGEAWRAAERKRDWPTRND
MAB_3429|M.abscessus_ATCC_1997 RGEPLAGINTVLQTVRDAGLRGPLWMTPPPAPNTAWLVSERKRSIPTQLD
Mflv_4207|M.gilvum_PYR-GCK AGPQSVDFDGVLAAATTAGVDLPVEILLPAEHGAAVTVSEIDKPYRWTTD
Mvan_2159|M.vanbaalenii_PYR-1 VDRLAVDYDGVLAAAAGAGARSPVEITVPAEHGHGVTVTEIDEPYRWTTN
. : ** :. .* *: : *. . .:* .. :
MSMEG_6570|M.smegmatis_MC2_155 SIAVDAQTGAVTDRVD-FADWPLLAKLTRWTIDAHMGLLFGVVNQIILAV
TH_0807|M.thermoresistible__bu AVAVDPVSGEITDRVD-FADWPLLAKLTRWTIDAHMGILFGVVNQVVLIL
MAB_3429|M.abscessus_ATCC_1997 AITVNPSSGEITGRSN-FSEWSLLQKSTEWAIDGHMGVLFGIPNQILVAL
Mflv_4207|M.gilvum_PYR-GCK AAAVNPGDLTVTGTVDYWRDYSLIAKLADWGIRGHMGFLFGLLNQLLLLG
Mvan_2159|M.vanbaalenii_PYR-1 SAVVDPTDLSVTARIDYWSDYSLIAKLADWGIRAHMGFLFGLVNQLLLLG
: .*:. :* : : ::.*: * : * * .***.***: **:::
MSMEG_6570|M.smegmatis_MC2_155 SMIGLITLIVQGYRMWWQRRPTRGSTWAVGRPPRRGAIRRLPWWAVTAVA
TH_0807|M.thermoresistible__bu TAVGLIYLIVRGYRMWWQRRPVRGTAWAVGRPPLRGALRALGPLPATVLV
MAB_3429|M.abscessus_ATCC_1997 VVIGLITVITRGYLMWWRRRPTKSGRWPV--PPRRGGLLALKPLELAILA
Mflv_4207|M.gilvum_PYR-GCK IAVGLLAVIVRGYRMWWQRRPTRGSRWAVGRPPARGGLRRLRPLTVTALV
Mvan_2159|M.vanbaalenii_PYR-1 IAVGLVTLIVRGYRMWWQRRPTRGSDWAFGRPPVRGGMRGLSPVVRLWVI
:**: :*.:** ***:***.:. *.. ** **.: * :
MSMEG_6570|M.smegmatis_MC2_155 VTAVVIGWCLPLFGLSLAAFLVIDAATAYMKR----KQNENA--------
TH_0807|M.thermoresistible__bu LTAALVGWFLPLFGLSLLAFVAVDAAVAWYKR----RRT-----------
MAB_3429|M.abscessus_ATCC_1997 VVVVGVGWFMPLLGISLAAFLAIDLAGGLVAS----RRGTAASGG-----
Mflv_4207|M.gilvum_PYR-GCK AGAVTVGWFLPLLGLTLAAFALTDLILGSIKKNASLKKNASLKKNASLNE
Mvan_2159|M.vanbaalenii_PYR-1 AAAVAVGWFLPLLGLSLAAFVAVDLCIGAVKQ----RK---VKSDV----
.. :** :**:*::* ** * . ::
MSMEG_6570|M.smegmatis_MC2_155 --------
TH_0807|M.thermoresistible__bu --------
MAB_3429|M.abscessus_ATCC_1997 --------
Mflv_4207|M.gilvum_PYR-GCK NTENSHVR
Mvan_2159|M.vanbaalenii_PYR-1 --------