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RLTAAQARRVAVAAQGFHEPRPSGPVTRAHLKRLIARLQVLQLDSVSVAVRAHYAPVFSRLGPYDRDVLD RAAWSHSARSPRLLVEYWAHEAALMAVDDWPLLRWRMREYEHGRWGREIVKKNGKLAADIVEAVTALGPC TAGQIEAYLESEPRRTGGSVKKAMWDRSDTKWVAEALWSSGVLTTATRVGFARHYDLTERVLPADVVARR VDEADALRELTLRAATALGVATEADLRDYFRLGARQVRPAITDLLDAGEIERVEVDGWDAPAYLRAGQTV PRRDRGTALLCPFDPLIFFRPRVERLFGGFHYRIEIYVPQPKRRYGYYVWPFLLDGDLVGRVDLKADRTA GALQVLGAYCEGGRDGPRVAAELATALRQMADWLGLDDVVVAERGDLSAHLRAALVS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4005 | - | - | 100% (408) | hypothetical protein Mflv_4005 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2783c | - | 2e-11 | 49.40% (83) | hypothetical protein Mb2783c |
| M. tuberculosis H37Rv | Rv2762c | - | 2e-11 | 49.40% (83) | hypothetical protein Rv2762c |
| M. leprae Br4923 | MLBr_01517 | - | 7e-15 | 54.55% (77) | hypothetical protein MLBr_01517 |
| M. abscessus ATCC 19977 | MAB_3087c | - | 1e-158 | 67.90% (405) | hypothetical protein MAB_3087c |
| M. marinum M | MMAR_1958 | - | 1e-164 | 70.79% (404) | hypothetical protein MMAR_1958 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2679 | - | 1e-171 | 75.31% (401) | hypothetical protein MSMEG_2679 |
| M. thermoresistible (build 8) | TH_0690 | - | 1e-159 | 73.68% (380) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2180 | - | 1e-161 | 70.05% (404) | hypothetical protein MUL_2180 |
| M. vanbaalenii PYR-1 | Mvan_2383 | - | 0.0 | 83.99% (406) | hypothetical protein Mvan_2383 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4005|M.gilvum_PYR-GCK -------MRLTAAQARRVAVAAQGFHEPRPSGPVTRAHLKRLIARLQVLQ
Mvan_2383|M.vanbaalenii_PYR-1 MAPPLRSATLTAAQARRIAVGAQGFHEPKPAGPVTRAHLKRLIARLQVLQ
MSMEG_2679|M.smegmatis_MC2_155 ------MATLTVAQARRIAVAAQGFHEPRPRGSVTRAHVRRLINRIQVLQ
MLBr_01517|M.leprae_Br4923 --------------------------------------------------
MAB_3087c|M.abscessus_ATCC_199 ----MSRSALTVAQARRIAIAAQGFTDTS-ATAVTRAHLRKLISRIQVLQ
TH_0690|M.thermoresistible__bu ---------------------------------VTRAHLRRLIERIQVLQ
Mb2783c|M.bovis_AF2122/97 --------------------------------------------------
Rv2762c|M.tuberculosis_H37Rv ------MSAATAAWDRRAAVVVGGVAEPGSAGPIAGADRKRLISRIQVRQ
MMAR_1958|M.marinum_M ------MSTLTVAQARRVAVAAQGFAEPKPAGRINKAHLRRLISRIQVLQ
MUL_2180|M.ulcerans_Agy99 ------MSTLTVAQARRVAVAAQGFAEPKPAGRINKAHLRRLISRIQVLQ
Mflv_4005|M.gilvum_PYR-GCK LDSVSVAVRAHYAPVFSRLGPYDRDVLDRAAWSHSARSPRLLVEYWAHEA
Mvan_2383|M.vanbaalenii_PYR-1 LDSVSVAVRAHYAPVFSRIGPYDRDLLDRAAWSHSARSPRLLVEYWAHEA
MSMEG_2679|M.smegmatis_MC2_155 LDSVSVAVRAHYAPVFSRLGPYDRDVLDRAAWSHTARSPRLLVEYWAHEA
MLBr_01517|M.leprae_Br4923 --------------------------------------------------
MAB_3087c|M.abscessus_ATCC_199 LDSVSVAVRAHYAPVFSRLGPYDRALLDDAAWSHSARTPRLLIEYWAHEA
TH_0690|M.thermoresistible__bu LDSVSVSVRAHYAPVFSRLGPYDRDVLDRAAWDHSARAPRLLVEYWAHEA
Mb2783c|M.bovis_AF2122/97 --------------------------------------------------
Rv2762c|M.tuberculosis_H37Rv LDSA----------------------------------------------
MMAR_1958|M.marinum_M LDSVSVAVRAHYAPVFSRLGPYDREVLDRVAWGP--PSSRLLAEYWAHEA
MUL_2180|M.ulcerans_Agy99 LDSVSVAVRAHYAPVFSRLGPYDREVLDRVAWGP--PSSRLLAEYWAHEA
Mflv_4005|M.gilvum_PYR-GCK ALMAVDDWPLLRWRMREYEHGRWGREIVKKNGKLAADIVEAVTALGPCTA
Mvan_2383|M.vanbaalenii_PYR-1 ALMAVDDWPLLRWRMQEYRHGRWGVEIVKKNAKLAESVVEAVAALGPSTA
MSMEG_2679|M.smegmatis_MC2_155 ALMAVEDWPLLRWRMREYTHGRWGREIVKKNPRLADDIVSAVAELGPATA
MLBr_01517|M.leprae_Br4923 --------------------------------------------------
MAB_3087c|M.abscessus_ATCC_199 ALMSIQDWPLMRWRMREYRHGRWARKFVEENPGLVDEVLAAVAELGPCTA
TH_0690|M.thermoresistible__bu ALMAVDDWPLLRWRMRRYTHGRWGTHIVKRNPKLVEEVVAAVAELGPSTA
Mb2783c|M.bovis_AF2122/97 --------------------------------------------------
Rv2762c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1958|M.marinum_M ALMAVDDWPLLRWRMRQYRHGRWGTEIVKANPRLVDDVVAAVAELGPSSA
MUL_2180|M.ulcerans_Agy99 ALMAVEDWPLLRWRMRQYRHGRWGTEIVKANPRLVDDVVAAVAELGPSSA
Mflv_4005|M.gilvum_PYR-GCK GQIEAYLESEPRRTGGSVKKAMWDRSDTKWVAEALWSSGVLTTATRVGFA
Mvan_2383|M.vanbaalenii_PYR-1 GQIEAYLESEPRGR----KGPWWDRSETKWVAEALWSAGVLTTATRVGFA
MSMEG_2679|M.smegmatis_MC2_155 GQIEAHLEAEPRGR----KGPWWDRSDTKWVAEALFAAGILTTATRVGFA
MLBr_01517|M.leprae_Br4923 --------------------------------------------------
MAB_3087c|M.abscessus_ATCC_199 GQIEAYLEREAPGR----KGPWWDRSETKWIAEALFSSGELTTDKRVGFS
TH_0690|M.thermoresistible__bu GQIEEHLGTRPRRA----KGAWWNRSDTKWVTEALFAAGVLTTATRVGFA
Mb2783c|M.bovis_AF2122/97 --------------------------------------------------
Rv2762c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1958|M.marinum_M GQIEAHLAAEPRGG----QGPWWNRSDTKWVAEALFASGVLTTATRLGFA
MUL_2180|M.ulcerans_Agy99 GQIEAHLAAEPRGG----QGPWWNRSDTKWVAEALFASGVLTTATRLGFA
Mflv_4005|M.gilvum_PYR-GCK RHYDLTERVLPADVVARRVDEADALRELTLRAATALGVATEADLRDYFRL
Mvan_2383|M.vanbaalenii_PYR-1 RHYDLTERVLPAEVVDRQVDEADAVRELTLRAATSLGVATEADLRDYFRL
MSMEG_2679|M.smegmatis_MC2_155 RHYDLAENVLPPEVLAREVGDEEAVRELALRAATALGVGTEADIRDYFRM
MLBr_01517|M.leprae_Br4923 -----------------------------------MGV------------
MAB_3087c|M.abscessus_ATCC_199 RHYQLAHKVIPAEIYQREVSDEEAVLELARRAVGALGVGTEADIRDYFRL
TH_0690|M.thermoresistible__bu RHYDLTERVLPAEVVNRRVDDDEAICRLVLRAAGALGVATEADLRDYFRL
Mb2783c|M.bovis_AF2122/97 --------------------------------------------------
Rv2762c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1958|M.marinum_M RHYDLVERVLPPEVLARQVDDDEAVRELVLRAASALGVGTEADIRDYFRL
MUL_2180|M.ulcerans_Agy99 RHYDLVERVLPPEVLARQVDDDEAIRELVLRAASALGVGTEADIRDYFRL
Mflv_4005|M.gilvum_PYR-GCK GARQVRPAITDLLDAGEIERVEVDGWDAPAYLRAGQTVPRRDRGTALLCP
Mvan_2383|M.vanbaalenii_PYR-1 GARQVKPAIADLLAAGHIERVDVEGWPAPAYLRAGQTVPRRDRGTALLCP
MSMEG_2679|M.smegmatis_MC2_155 NAKQVKPAIAKLVADGELEPVDIDG--TPAYLRTGQIIPRRDRGTALLCP
MLBr_01517|M.leprae_Br4923 ---------AELVAAGEIESVTVQGVGARHICDTAKAVPRVDRGTALLCL
MAB_3087c|M.abscessus_ATCC_199 SAGQIKPALAVLADAGEVERVSVDGWGAPAYLAAGRTIPRADQGTALLCP
TH_0690|M.thermoresistible__bu SAAQTRPAVAALVAAGELEPVDVDGWGAPAYLRVGQTIPRRDRGTALLCP
Mb2783c|M.bovis_AF2122/97 --------------------------------------------------
Rv2762c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1958|M.marinum_M SAQQVKPALADLVAAGEVEPVQVQGWSAPAYLRAGRSLPRRDRGTALLCP
MUL_2180|M.ulcerans_Agy99 SAQQVKPALADLVAAGEVEPVQVQGWSAPTYLRAGRSLPRRDRGTALLCP
Mflv_4005|M.gilvum_PYR-GCK FDPLIFFRPRVERLFGGFHYRIEIYVPQPKRRYGYYVWPFLLDGDLVGRV
Mvan_2383|M.vanbaalenii_PYR-1 FDPLIFFRPRVERLFGGFHYRIEIYTPAAKRRFGYYVWPFLLDGDLVGRV
MSMEG_2679|M.smegmatis_MC2_155 FDPLIFFRPRVQRLFD-FHYRIEIYVPAPQRQFGYYVWPFLLDGRLVGRV
MLBr_01517|M.leprae_Br4923 FDPVIFFWQWVEWLFG-FRYCIEIYTSAVKRQYSY---------------
MAB_3087c|M.abscessus_ATCC_199 FDPLIFFRPRVERLFD-FHYRIEIYTPAAKRQYGYYVWPFLLDGQLVGRV
TH_0690|M.thermoresistible__bu FDPLIFFRPRVQRLFD-FHYRIEIYTPAAKRKYGYYVWPFLLDGQLVGRV
Mb2783c|M.bovis_AF2122/97 --------------------------MAAKRRHLYYVRP--LDGHPVARV
Rv2762c|M.tuberculosis_H37Rv -------------------------AVAAKRRHLYYVRP--LDGHPVARV
MMAR_1958|M.marinum_M FDPLIFFRPRVQRLFD-FHYRIEIYTPAAQRQYGYYVWPLLLDGQLVGRV
MUL_2180|M.ulcerans_Agy99 FDPLIFFRPRVQRLFD-FHYRIEIYTLAAQRQYGYYVRPLLLDGQLVGRV
:*:. *
Mflv_4005|M.gilvum_PYR-GCK DLKADRTAGALQVLGAYCEGGRDGPRVAAELATALRQMADWLGLDDVVVA
Mvan_2383|M.vanbaalenii_PYR-1 DLKADRVSGTLQVLGAFTEDGRDRARVARALATELQSMAGWLGLADVTVG
MSMEG_2679|M.smegmatis_MC2_155 DLK--RTDAALQVLGAFSEDGRDRAHVAQALAGELRSMAGWLGVPAVEVG
MLBr_01517|M.leprae_Br4923 ----------IFVVAAAKR----PVGRAC---------------------
MAB_3087c|M.abscessus_ATCC_199 DLKADRAAGTLNVVGAFAEEGRDPVGIAGPLAEQLVSMASWLGLERVAVG
TH_0690|M.thermoresistible__bu DLKRTDN--ALHVVGAFLEPGQEPARVAPALAAQLQSMASWLGVGAVTVG
Mb2783c|M.bovis_AF2122/97 DRKTDRAADSLPVAGVLGELDIPPVTVAEGLAGELASMASWLGLGGIAVS
Rv2762c|M.tuberculosis_H37Rv DRKTDRAADSLPVAGVLGELDIPPVTVAEGLAGELASMASWLGLGGIAVS
MMAR_1958|M.marinum_M DLKADRSTDTLLVVGAFAEPDASGPRVAAALAGELASMAPWLGLSGISVS
MUL_2180|M.ulcerans_Agy99 DLKADRSTDTLLVVGAFAEPDASGPRVAAALAGELASMAPWLGLSGVSVS
: * .. . *
Mflv_4005|M.gilvum_PYR-GCK ERGDLSAHLRAALVS---
Mvan_2383|M.vanbaalenii_PYR-1 HRGDLATELGDALVS---
MSMEG_2679|M.smegmatis_MC2_155 DRGDLAPVLREVV-----
MLBr_01517|M.leprae_Br4923 ------------------
MAB_3087c|M.abscessus_ATCC_199 ERGDLVRPLGAVLRTTP-
TH_0690|M.thermoresistible__bu ERGDLVGPLSTAIRRGD-
Mb2783c|M.bovis_AF2122/97 TRGDLAGELCAATKRTNG
Rv2762c|M.tuberculosis_H37Rv TRGDLAGELCAATKRTNG
MMAR_1958|M.marinum_M GRGDLAGELAIAVRRTG-
MUL_2180|M.ulcerans_Agy99 GRGDLAGELAIAVRRTG-