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GALRPAAVAGAFAAGLATGVLTRSQRNTHAGQDELPESAASAAPEPAEAEKVDAPPADDPAKPESPTDLT RPSWLFVLRKTAREFTHDQCTDLAAALTYYAVLSLFPALVVVMSLLGVIGQSERTADAVLGIVDDVSPGA AVDVLREPIQQLVNAPSAGLTLVLGIVGALWSASGFVGAFGRAMNRIYEVEEGRPGWKLRLQQLFLTLVG LIVAATAALLLAVSGPVAEAVGGYLGVGATGLTVWNIARWPLLLVLVVFGVAMLYYVSPNVRQPKFRWIS VGAAIAIVTWVCASLGFGFYVANFGNYNKTFGTLAGVIVFLLWLWLTNLALLFGAEVDAELERGRQLQAG IRAEDTLKLPLRDTSLIEKNKAKEHETRLRGRVLRRSRGRHDGFGDDPQG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3869 | - | - | 100% (401) | putative ribonuclease BN |
| M. gilvum PYR-GCK | Mflv_3945 | - | 2e-12 | 26.33% (281) | ribonuclease BN |
| M. gilvum PYR-GCK | Mflv_3865 | - | 2e-09 | 26.74% (258) | ribonuclease BN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2726 | - | 3e-15 | 25.64% (273) | hypothetical protein Mb2726 |
| M. tuberculosis H37Rv | Rv2707 | - | 3e-15 | 25.64% (273) | hypothetical protein Rv2707 |
| M. leprae Br4923 | MLBr_01017 | - | 3e-14 | 24.64% (276) | hypothetical protein MLBr_01017 |
| M. abscessus ATCC 19977 | MAB_3025 | - | 6e-16 | 27.50% (280) | ribonuclease BN |
| M. marinum M | MMAR_2006 | - | 2e-17 | 26.41% (284) | hypothetical protein MMAR_2006 |
| M. avium 104 | MAV_3600 | - | 6e-16 | 26.86% (283) | hypothetical protein MAV_3600 |
| M. smegmatis MC2 155 | MSMEG_2755 | - | 1e-11 | 23.72% (333) | hypothetical protein MSMEG_2755 |
| M. thermoresistible (build 8) | TH_1245 | - | 3e-20 | 27.22% (327) | conserved hypothetical proline rich protein |
| M. ulcerans Agy99 | MUL_3347 | - | 2e-17 | 26.41% (284) | hypothetical protein MUL_3347 |
| M. vanbaalenii PYR-1 | Mvan_2454 | - | 4e-15 | 26.64% (304) | ribonuclease BN |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2726|M.bovis_AF2122/97 --------------------------------------------------
Rv2707|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2006|M.marinum_M --------------------------------------------------
MUL_3347|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01017|M.leprae_Br4923 --------------------------------------------------
MAV_3600|M.avium_104 --------------------------------------------------
MSMEG_2755|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2454|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3025|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1245|M.thermoresistible__bu MPDGIGLSVGATTLAAVVVGRTALTRTPVLTRYPHRPPEVGVPSENPQLT
Mflv_3869|M.gilvum_PYR-GCK --------------------------------------------------
Mb2726|M.bovis_AF2122/97 --------------------------------------------------
Rv2707|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2006|M.marinum_M --------------------------------------------------
MUL_3347|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01017|M.leprae_Br4923 --------------------------------------------------
MAV_3600|M.avium_104 --------------------------------------------------
MSMEG_2755|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2454|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3025|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1245|M.thermoresistible__bu ERGLIITDFVDRVGDPVGIVAPDGSTHPGEAVLADALHALWRTVAPLGSP
Mflv_3869|M.gilvum_PYR-GCK --------------------------------------------------
Mb2726|M.bovis_AF2122/97 --------------------------------------------------
Rv2707|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2006|M.marinum_M --------------------------------------------------
MUL_3347|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01017|M.leprae_Br4923 --------------------------------------------------
MAV_3600|M.avium_104 --------------------------------------------------
MSMEG_2755|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2454|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3025|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1245|M.thermoresistible__bu DDPIGVAHPAHWQPVAVEALRGRLAAQRDQAPVLAQAPLVSDAEAALTAL
Mflv_3869|M.gilvum_PYR-GCK --------------------------------------------------
Mb2726|M.bovis_AF2122/97 --------------------------------------------------
Rv2707|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2006|M.marinum_M --------------------------------------------------
MUL_3347|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01017|M.leprae_Br4923 --------------------------------------------------
MAV_3600|M.avium_104 --------------------------------------------------
MSMEG_2755|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2454|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3025|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1245|M.thermoresistible__bu QADPGLPTSGIVALCDFGGTGTSLTIADAADGYRPVAPTLRHLDLSGELI
Mflv_3869|M.gilvum_PYR-GCK --------------------------------------------------
Mb2726|M.bovis_AF2122/97 --------------------------------------------------
Rv2707|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2006|M.marinum_M --------------------------------------------------
MUL_3347|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01017|M.leprae_Br4923 --------------------------------------------------
MAV_3600|M.avium_104 --------------------------------------------------
MSMEG_2755|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2454|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3025|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1245|M.thermoresistible__bu DQALLRHVLADLTEAGVVDASGTSAIGSLSRLRAQCRTAKERLSTTAVTT
Mflv_3869|M.gilvum_PYR-GCK --------------------------------------------------
Mb2726|M.bovis_AF2122/97 --------------------------------------------------
Rv2707|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2006|M.marinum_M --------------------------------------------------
MUL_3347|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01017|M.leprae_Br4923 --------------------------------------------------
MAV_3600|M.avium_104 --------------------------------------------------
MSMEG_2755|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2454|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3025|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1245|M.thermoresistible__bu LTAEAPGRPHELRLTRDELDAVLRPPLDEFLTAVQYTLDRNGIRPSDLTA
Mflv_3869|M.gilvum_PYR-GCK --------------------------------------------------
Mb2726|M.bovis_AF2122/97 --------------------------------------------------
Rv2707|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2006|M.marinum_M --------------------------------------------------
MUL_3347|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01017|M.leprae_Br4923 --------------------------------------------------
MAV_3600|M.avium_104 --------------------------------------------------
MSMEG_2755|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2454|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3025|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1245|M.thermoresistible__bu VATVGGGARIPLITAALSERFRVPVVTTPQPELTAAIGAGLTAVRALQAG
Mflv_3869|M.gilvum_PYR-GCK ----------------------------------MGALRPAAVAGAFAAG
Mb2726|M.bovis_AF2122/97 ----------------------------------------------MSDQ
Rv2707|M.tuberculosis_H37Rv ----------------------------------------------MSDQ
MMAR_2006|M.marinum_M ----------------------------------------------MSDQ
MUL_3347|M.ulcerans_Agy99 ----------------------------------------------MSEQ
MLBr_01017|M.leprae_Br4923 ----------------------------------------------MSGQ
MAV_3600|M.avium_104 ----------------------------------------------MSDQ
MSMEG_2755|M.smegmatis_MC2_155 ----------------------------------------------MTGQ
Mvan_2454|M.vanbaalenii_PYR-1 ----------------------------------------------MDDQ
MAB_3025|M.abscessus_ATCC_1997 ----------------------------------------------MSEK
TH_1245|M.thermoresistible__bu PADEATQWAAAVPDQADTQLWDGADQPGSDQLGADPTGAAPALAWSQADD
Mflv_3869|M.gilvum_PYR-GCK LATGVLTRSQRNTHAGQDELPESAASAAPEPAEAEKVDAPPADDPAKPES
.
Mb2726|M.bovis_AF2122/97 VP-------------------KPHRHHIWRITRRTLSKSWDDSIFSESAQ
Rv2707|M.tuberculosis_H37Rv VP-------------------KPHRHHIWRITRRTLSKSWDDSIFSESAQ
MMAR_2006|M.marinum_M VP-------------------RPSRHHIWRISLRTLSKSWDDSIFSESAQ
MUL_3347|M.ulcerans_Agy99 VP-------------------RPSRHHIWRISLRTLSKSWDDSIFSESAQ
MLBr_01017|M.leprae_Br4923 VY-------------------KPTRQHIWRISLRTLSKSWDDSIFSESAQ
MAV_3600|M.avium_104 VA-------------------KPSRHHIWRITLRTLSKSWDDSIFSESAQ
MSMEG_2755|M.smegmatis_MC2_155 P--------L---------PVPPSRHHIRHIAKRTLSKSWDDSIFSESAQ
Mvan_2454|M.vanbaalenii_PYR-1 SERPDVRPTQ---------RARPSRHHIRHITIRALSKSWDDSIFSESAQ
MAB_3025|M.abscessus_ATCC_1997 PR------------------HVSFGRDVLHVMRRTAVKSWDDSIFAQSAQ
TH_1245|M.thermoresistible__bu VPEVSDVYAPXXXXRSLYARCPAPVRHAWRLTDRTVRAASADRVPGLAAE
Mflv_3869|M.gilvum_PYR-GCK PT-------------------DLTRPSWLFVLRKTAREFTHDQCTDLAAA
: :: * :*
Mb2726|M.bovis_AF2122/97 AAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSALSTAHSFFSPS
Rv2707|M.tuberculosis_H37Rv AAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSALSTAHSFFSPS
MMAR_2006|M.marinum_M AGFWSALSLPPLLLGMLGSLAYVAPLFGQDTLPAIEKTIISMTHRFFSPS
MUL_3347|M.ulcerans_Agy99 AGFWSALSLPPLLLGMLGSLAYVAPLFGQDTLPAIEKTIISMTHRFFSPS
MLBr_01017|M.leprae_Br4923 AAFWSALSLPPLVLGMLGSLAYVAPLFGEDTLPTIERRVISMAHSFFSPS
MAV_3600|M.avium_104 AGFWSALSLPPLLLGLLGTLAYVAPLFGPDMLPSILRQLISTAHSVFSPS
MSMEG_2755|M.smegmatis_MC2_155 AAFWCALSLPPLLLGMLGSLAYIAPLFGPETLPTIQNQLITAANSFFSPN
Mvan_2454|M.vanbaalenii_PYR-1 AAFWCALSLPPLLLGMLGSLAYVAPLFGPDTLVTIQSQLVSLAGRFFSPN
MAB_3025|M.abscessus_ATCC_1997 AAFWQVLSLPPLLLGILGSLTFVGPLFGPDTLPEIQERLVRVANSVFSKS
TH_1245|M.thermoresistible__bu AALFTLISLPALLLAVFGSLGYIAEALGPDGTEGLRRLVLDVPQSFLTEE
Mflv_3869|M.gilvum_PYR-GCK LTYYAVLSLFPALVVVMSLLGVIG------QSERTADAVLGIVDDVSPGA
: :** . :: ::. * :. : . .
Mb2726|M.bovis_AF2122/97 VVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHDQ
Rv2707|M.tuberculosis_H37Rv VVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHDQ
MMAR_2006|M.marinum_M VVDEIIEPTIRDITANARGEVVSVGFLISLWAGSSAISSYVDAIVEAHDQ
MUL_3347|M.ulcerans_Agy99 VVDEIIEPTIRDITANARGEVVSVGFLISLWAGSSAISSYVDAIVEAHDQ
MLBr_01017|M.leprae_Br4923 VVNEIIEPTISDVNNGARGEVVSLGFLISLWAGSSAISAFVDAVVKAHDQ
MAV_3600|M.avium_104 VVNEIIEPTVRDIANNARGEVVSLGFLISLWAGSSAISAFVDSVVEAHDQ
MSMEG_2755|M.smegmatis_MC2_155 VVNEIIEPTIRDIVKGARGEVVSIGFVISLWAGSSAVSAFVDSIVEAHDQ
Mvan_2454|M.vanbaalenii_PYR-1 VVSEIIEPTVRDIVRGARGEVVSLGFVISLWAGSSAISAFVDSITEAHDQ
MAB_3025|M.abscessus_ATCC_1997 VVTEIIEPTIIDIMRDGRGEVVSIGFVISLWAGSSAISSFVDSVVEAHDQ
TH_1245|M.thermoresistible__bu TFG-FYAVMVEDVLTRRRGSVVSIGLLLSLWTGSRAVNRYLETITIAYGV
Mflv_3869|M.gilvum_PYR-GCK AVDVLREPIQQLVNAPSAGLTLVLGIVGALWSASGFVGAFGRAMNRIYEV
.. : : * . :*:: :**:.* :. : :: :
Mb2726|M.bovis_AF2122/97 TPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVG---PRKVSEHIP----
Rv2707|M.tuberculosis_H37Rv TPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVG---PRKVSEHIP----
MMAR_2006|M.marinum_M TPLRHPVRQRFFALFLYVVGLLFIVISAPVAVMG---PRKVSEHIP----
MUL_3347|M.ulcerans_Agy99 TPLRHPVRQRFFALFLYVVGLLFIVISAPVAVMG---PRKVSEHIP----
MLBr_01017|M.leprae_Br4923 TLLRHPVKQRLFALFLYIAMLAFVVATAPLVVVG---PRKVTKLIP----
MAV_3600|M.avium_104 TPLRHPVRQRFFALFLYVVMLVGVVATAPLVVVG---PRKVGEHIP----
MSMEG_2755|M.smegmatis_MC2_155 TPLRHPVRQRFYALGLYVVMLVGAIAAAPLVALG---PRKIAEQLP----
Mvan_2454|M.vanbaalenii_PYR-1 TPLRHPVRQRFYALGLYVVMLVGAIVAAPFLALG---PRKVAEFIP----
MAB_3025|M.abscessus_ATCC_1997 TPLRHPVRQRFFALGLYVAALAMAVVTLPMVALG---PKRIAEVVP----
TH_1245|M.thermoresistible__bu AP-RPVWRRRLIALGLTAGGLVGAAAVLPPLVVG---PQLVQELAPPAMR
Mflv_3869|M.gilvum_PYR-GCK EEGRPGWKLRLQQLFLTLVGLIVAATAALLLAVSGPVAEAVGGYLG--VG
* : *: * * * .:. .. :
Mb2726|M.bovis_AF2122/97 ESLANLLRYGYYPALILGLTVGVILLYRVALPVPLP-THRLVLGAVLAIA
Rv2707|M.tuberculosis_H37Rv ESLANLLRYGYYPALILGLTVGVILLYRVALPVPLP-THRLVLGAVLAIA
MMAR_2006|M.marinum_M DNMSNLMHYGYYPALIAVLTVGVIILYRVSLPVPLP-THRLILGAVLAMA
MUL_3347|M.ulcerans_Agy99 DSMSNLMHYGYYPALIAVLTVGVIILYRVSLPVPLP-THRLILGAVLAMA
MLBr_01017|M.leprae_Br4923 HSWANMLHLGYYPAVIVSLLVAVMILYRVALPIPLP-THRLVFGAILATA
MAV_3600|M.avium_104 LGLSNVLRYGYYPALIVGLTIAVMILYRVALPEPLP-SHRLILGAMLATT
MSMEG_2755|M.smegmatis_MC2_155 DSWDNALHYGYYPALFFAVALFVTVLYRVSLPEPLP-THRLLLGTVLATV
Mvan_2454|M.vanbaalenii_PYR-1 DSWDSALQFAYYPVLFVALVVSVNLLYRVSLPKPLP-SHRLLLGSVLAAA
MAB_3025|M.abscessus_ATCC_1997 DSWNSLLRYGYFPLLGIALVALVTLLYRVSLPRPLP-SHRLWIGALLAVT
TH_1245|M.thermoresistible__bu AATVQMLDAMFWPALILAILVGLVSFYHFGVPWQTP-WRRDLPGAVLAMV
Mflv_3869|M.gilvum_PYR-GCK ATGLTVWNIARWPLLLVLVVFGVAMLYYVSPNVRQPKFRWISVGAAIAIV
:* : : : :* .. * : *: :* .
Mb2726|M.bovis_AF2122/97 VFLIATLGLRVYLAWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELN
Rv2707|M.tuberculosis_H37Rv VFLIATLGLRVYLAWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELN
MMAR_2006|M.marinum_M VFLIATLGLRFYLGWITHTGYTYGALSTPIAFLLFAFFGGFAVMIGAELN
MUL_3347|M.ulcerans_Agy99 VFLIATLGLRFYLGWITHTGYTYGALSTPIAFLLFAFFGGFAVMIGAELN
MLBr_01017|M.leprae_Br4923 VFVITTLGLRIYLKWITGTGYTYGALTTPIAFLLFAFFGGFAIMLGAEFN
MAV_3600|M.avium_104 VFVTATLGLRFYLRWITSTGYTYGALSTPIAFLLFAFFGGFAIMLGAELN
MSMEG_2755|M.smegmatis_MC2_155 VFLVTTVGLRVYLTWITSTGYTYGALATPIAFLLFAFFLGFAIMIGAELN
Mvan_2454|M.vanbaalenii_PYR-1 VFLIATWGLRVYLTWITSTGYTYGALATPIAFLLFAFFLGFAIMIGAELN
MAB_3025|M.abscessus_ATCC_1997 FFAIASLGLRFYLNWITGTGYTYGALATPIAFLLFAFMLGFAIVLGAELN
TH_1245|M.thermoresistible__bu LWLLASAGLRAYLAVSVRDEAVYAQLAVPIAVVLWLYVTAFAVLVGAEFN
Mflv_3869|M.gilvum_PYR-GCK TWVCASLGFGFYVANFGNYNKTFGTLAGVIVFLLWLWLTNLALLFGAEVD
: :: *: *: .:. *: *..:*: :. :*::.***.:
Mb2726|M.bovis_AF2122/97 AAVQEE------WPAPATHAHRLGNWLKARIGVG----TTTYSSTAQHSA
Rv2707|M.tuberculosis_H37Rv AAVQEE------WPAPATHAHRLGNWLKARIGVG----TTTYSSTAQHSA
MMAR_2006|M.marinum_M AAIQEE------WPAPATHAHRLRNWLRARTAAA----TGSADSESPQSN
MUL_3347|M.ulcerans_Agy99 AAIQEE------WPAPATHAHRLRNWLRARTAAA----TGSADSESPQSN
MLBr_01017|M.leprae_Br4923 ASIQEK------FPAPKTHTHRLHNWLTSRLHTDPGRNTVTTQTTQHRSG
MAV_3600|M.avium_104 AAVQEE------FPAPKTHAHRLRTWLFSRSPALARTVQTLASPIANPAT
MSMEG_2755|M.smegmatis_MC2_155 AAIQEE------WPAADTHATRVRKWIETRTRNG-GAEEPVRD--EPDPV
Mvan_2454|M.vanbaalenii_PYR-1 AAIEEE------FPAPDTHAKRFRWWLEAKAESLNGTTSPTAAPGEPRAA
MAB_3025|M.abscessus_ATCC_1997 AAIEEN------WPAGATHARQLREWLSPQNGQN-----GRDDGTPTQSP
TH_1245|M.thermoresistible__bu AEIERM------WPHDR-YPWRLRRRRDRRSRDG-----------SARMG
Mflv_3869|M.gilvum_PYR-GCK AELERGRQLQAGIRAEDTLKLPLRDTSLIEKNKAKEHETRLRGRVLRRSR
* ::. . .
Mb2726|M.bovis_AF2122/97 VAAE--PPS----
Rv2707|M.tuberculosis_H37Rv VAAE--PPS----
MMAR_2006|M.marinum_M TAVD--PPS----
MUL_3347|M.ulcerans_Agy99 TAVD--PPS----
MLBr_01017|M.leprae_Br4923 RAAELINPS----
MAV_3600|M.avium_104 QRREVAPAEPRG-
MSMEG_2755|M.smegmatis_MC2_155 PG---AAEEPSAS
Mvan_2454|M.vanbaalenii_PYR-1 AGGPVATSDAATS
MAB_3025|M.abscessus_ATCC_1997 EGC----------
TH_1245|M.thermoresistible__bu R------------
Mflv_3869|M.gilvum_PYR-GCK GRHDGFGDDPQG-