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RWAGQGVAVDDGALPGLQRLGLVRSVRTPQFDGITFHEVLCKTALNKIPAASMLPFRFTVNGYRGCSHAC RYCFARPTHEYLEFDPGRDFDTQVVVKTNVAEVLRRELRRPSWSRETVALGTNTDPYQRAEGRYALMPGI IGALTDFGTPFSILTKGTLLRRDLPLLTDASRRVDVSVAVSLAVGDPDLHGRLEPGTPTPEARLSLISAI REAGLRCHVMVAPVLPGLTDSDDHLDDLLGRIAGAGATSATVFGLHLRGSTRGWFMDWLAEAYPDLVGEY RRLYRRGAYLPAEYRADLACRAAPLLARHGLARAPRFAAPLPGAGPVDAAPELQPTLF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3795 | - | - | 100% (339) | radical SAM domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2609c | - | 1e-144 | 75.00% (344) | hypothetical protein Mb2609c |
| M. tuberculosis H37Rv | Rv2578c | - | 1e-144 | 75.00% (344) | hypothetical protein Rv2578c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2868c | - | 1e-138 | 70.21% (339) | hypothetical protein MAB_2868c |
| M. marinum M | MMAR_2148 | - | 1e-145 | 74.42% (344) | hypothetical protein MMAR_2148 |
| M. avium 104 | MAV_3456 | - | 1e-146 | 76.23% (345) | radical SAM domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2990 | - | 1e-149 | 75.52% (339) | Fe-S protein, radical SAM family protein |
| M. thermoresistible (build 8) | TH_0535 | - | 1e-151 | 78.30% (341) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1734 | - | 1e-144 | 73.84% (344) | hypothetical protein MUL_1734 |
| M. vanbaalenii PYR-1 | Mvan_2599 | - | 1e-173 | 87.32% (339) | radical SAM domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3795|M.gilvum_PYR-GCK -----MRWAGQGVAV-----DDGALPGLQRLGLVRSVRTPQFDGITFHEV
Mvan_2599|M.vanbaalenii_PYR-1 -----MRWAGQGIDV-----DDGALPGLQRIGLIRSVRTPQFDGITFHEV
TH_0535|M.thermoresistible__bu -----MRWASQSVAI-----DDGALPGLQRVGLVRSVRTPQFDGITFHEV
Mb2609c|M.bovis_AF2122/97 -----MRWARQAVAVNGMPVDDGALPGLQRIGLVRSVRAPQFDGITFHEV
Rv2578c|M.tuberculosis_H37Rv -----MRWARQAVAVNGMPVDDGALPGLQRIGLVRSVRAPQFDGITFHEV
MAV_3456|M.avium_104 -----MRWASQAVAVNGKPVEDGALPGLQRLGLVRSVRAPQFEGITFHEV
MMAR_2148|M.marinum_M -----MRWCAQALAVNGEPVDDGALPGLQRIGLVRSVRSPHFEGMTFHEV
MUL_1734|M.ulcerans_Agy99 -----MRWCAQALAVNGEPVDDGALPGLQRIGLVRSVRSPHFEGMTFHEV
MSMEG_2990|M.smegmatis_MC2_155 MFDGGVRWDEQAVRV-----DDGALPGLARVGFVRSVRAPEFEGITFHEV
MAB_2868c|M.abscessus_ATCC_199 -----MRWDGQALAA-----DDGALPGLERIGLVRSVRTPEFEGITFHEV
:** *.: :******* *:*::****:*.*:*:*****
Mflv_3795|M.gilvum_PYR-GCK LCKTALNKIPAASMLPFRFTVNGYRGCSHACRYCFARPTHEYLEFDPGRD
Mvan_2599|M.vanbaalenii_PYR-1 LCKSALNKIPAASMLPFRYTVNGYRGCSHACRYCFARPTHEYLDFDSGRD
TH_0535|M.thermoresistible__bu LCKSALNKVPNAAMLPFRYTVNGYRGCSHACRYCFARPTHEYLDLDCGTD
Mb2609c|M.bovis_AF2122/97 LCKSALNKVPNAAALPFRYTVNGYRGCSHACRYCFARPTHEYLDFNPGTD
Rv2578c|M.tuberculosis_H37Rv LCKSALNKVPNAAALPFRYTVNGYRGCSHACRYCFARPTHEYLDFNPGTD
MAV_3456|M.avium_104 LCKSALNKVPNASALPFRYTVNGYRGCSHACRYCFARPSHEYLELNCGND
MMAR_2148|M.marinum_M LCKSALNKVPNAAALPFRYTVNGYRGCTHACRYCFARPTHEYLDFDSGAD
MUL_1734|M.ulcerans_Agy99 LCKSALNKVPNAAALPFRYTVNGYRGCMHACRYCFARPIHEYLDFDSGAD
MSMEG_2990|M.smegmatis_MC2_155 LCKSALNKVPAASALPFRFTVNGYRGCTHACRYCFARPTHEYLDFDPGVD
MAB_2868c|M.abscessus_ATCC_199 LCKSALNKVPTVSMLPFRFTVNAFRGCAHACRYCFARPTHEYLEFDSGAD
***:****:* .: ****:***.:*** ********** ****::: * *
Mflv_3795|M.gilvum_PYR-GCK FDTQVVVKTNVAEVLRRELRRPSWSRETVALGTNTDPYQRAEGRYALMPG
Mvan_2599|M.vanbaalenii_PYR-1 FDTQVVVKTNVADVLRRELRRPSWTRETVALGTNTDPYQRAEGRYALMPG
TH_0535|M.thermoresistible__bu FDTQVVVKVNVADVLRRELRRPSWTRETVALGTNTDPYQRAEGRYALMPD
Mb2609c|M.bovis_AF2122/97 FDTQVVVKTNVAAVLRHELRRPSWRRETVALGTNTDPYQRAEGRYALMPG
Rv2578c|M.tuberculosis_H37Rv FDTQVVVKTNVAAVLRHELRRPSWRRETVALGTNTDPYQRAEGRYALMPG
MAV_3456|M.avium_104 FDTQVVVKTNVAQVLRRELRRPSWRRETVALGTNTDPYQRAEGRYALMPG
MMAR_2148|M.marinum_M FDTQIVVKTNVAEVLRRELRRPSWRRETVALGTNTDPYQRAEGRYALMPG
MUL_1734|M.ulcerans_Agy99 FDTQIVVKTNVAEVLRRELRRPSWRRKTVALGTNTDPYQRAEGRYALMPG
MSMEG_2990|M.smegmatis_MC2_155 FDRQIVVKTNVVEVLRRELRRPSWTHETVALGTNTDPYQRAEGRYALMPG
MAB_2868c|M.abscessus_ATCC_199 FDNQIVVKTNVVPVLRKELGRKSWGRETVALGTNTDPYQRAEGRYQLMPG
** *:***.**. ***:** * ** ::****************** ***.
Mflv_3795|M.gilvum_PYR-GCK IIGALTDFGTPFSILTKGTLLRRDLPLLTDASRRVDVSVAVSLAVGDPDL
Mvan_2599|M.vanbaalenii_PYR-1 IIGALTDFGTPFSILTKGTLLRRDLPLLTEAARRVDVSVAVSLAVGDAEL
TH_0535|M.thermoresistible__bu IIRALADSHTPFSILTKGTLLRRDLPLIRDAAQQVPVSVAVSLAVGDADL
Mb2609c|M.bovis_AF2122/97 IIGALAASGTPLSILTKGTLLRRDLPLIAEAAQQVPVSVAVSLAVGDPEL
Rv2578c|M.tuberculosis_H37Rv IIGALAASGTPLSILTKGTLLRRDLPLIAEAAQQVPVSVAVSLAVGDPEL
MAV_3456|M.avium_104 IIGALAESGTPLSILTKGTLLRRDLPLIANAAAQVPVSVAVSLAVGDADL
MMAR_2148|M.marinum_M IIGALAGSGTPLSILTKGTLLRRDLPLLAEVSGQVPVSVAVSLAIADPDL
MUL_1734|M.ulcerans_Agy99 IIGALAGSGTPLSILTKGTLLRRDLPLLAEVSGQVPVSVAVSLAIADPDL
MSMEG_2990|M.smegmatis_MC2_155 IIGALADSYTPFSILTKGTLLRRDLGLIAEAARRVEVSVAVSLAIGDADL
MAB_2868c|M.abscessus_ATCC_199 VIGALADSGTPISILTKGTLLRRDLPLLSEAAGQVPVSLGISLAIGDEVL
:* **: **:************* *: :.: :* **:.:***:.* *
Mflv_3795|M.gilvum_PYR-GCK HGRLEPGTPTPEARLSLISAIREAGLRCHVMVAPVLPGLTDSDDHLDDLL
Mvan_2599|M.vanbaalenii_PYR-1 HSLVEPGTPSPEARLGLISAIRSAGLSCHVMVAPVLPGLTDSRDHLDDLL
TH_0535|M.thermoresistible__bu HRSVEPGTPTPEARLALISSIREAGLDCHVMVAPVLPYLTDSTDHLDDLL
Mb2609c|M.bovis_AF2122/97 HRDVESGTPTPQARLALITAIRAAGLDCHVMVAPVLPQLTDSGEHLDQLL
Rv2578c|M.tuberculosis_H37Rv HRDVESGTPTPQARLALITAIRAAGLDCHVMVAPVLPQLTDSGEHLDQLL
MAV_3456|M.avium_104 HRDVEPGTPTPQARLGLISAIRAAGLDCHVMVAPVLPYLTDSVEHLDDLL
MMAR_2148|M.marinum_M HKEIEPGTPAPQARLGLIAAIRDAGLDCHVMVAPVLPHLTDSAAHLDLLL
MUL_1734|M.ulcerans_Agy99 HKEIEPGTPAPQARLGLIAAIRDAGLDCHVMVAPVLPHLTDSAAHLDLLL
MSMEG_2990|M.smegmatis_MC2_155 HRDIEPGTPSPQARLALISAIRDAGLSCHVMVAPVLPYLTDSAEHLDDLL
MAB_2868c|M.abscessus_ATCC_199 HREVESGVPSPQARLALISAACEAGFQPHVMVAPVLPFLTDTVEHLDDLL
* :*.*.*:*:***.**:: **: ********* ***: *** **
Mflv_3795|M.gilvum_PYR-GCK GRIAGAGATSATVFGLHLRGSTRGWFMDWLAEAYPDLVGEYRRLYRRGAY
Mvan_2599|M.vanbaalenii_PYR-1 GRIAAAGATSATVFGLHLRGSTRGWFMDWLARTYPDLVGEYRRLYRRGAY
TH_0535|M.thermoresistible__bu GRIAAAGATGVTVFALHLRGSTRGWFMNWLARTHPQLVTPYRQLYRRGAY
Mb2609c|M.bovis_AF2122/97 GQIAAAGATGVTVFGLHLRGSTRGWFMCWLARAHPELVSRYRELYRRGPY
Rv2578c|M.tuberculosis_H37Rv GQIAAAGATGVTVFGLHLRGSTRGWFMCWLARAHPELVSRYRELYRRGPY
MAV_3456|M.avium_104 GQIAAAGAGSVTVFGLHLRGSTRGWFMEWLARSHPELVGRYRELYSRGAY
MMAR_2148|M.marinum_M GQIAAAGATGVTAFGLHLRGATRGWFMSWLARAHPDLVGTYRELYRRGAY
MUL_1734|M.ulcerans_Agy99 GQIAAAGATGVTAFGLHLRGATRGWFMSWLARAHPDLVGTYRELYRRGAY
MSMEG_2990|M.smegmatis_MC2_155 GRIAEAGATSVTAFGLHLRGSTRGWFMSWLASSHPELVWKYRQLYRKGAY
MAB_2868c|M.abscessus_ATCC_199 GRIADAGAAGVTVFPLHLRGTTRGWFMSWISHSHPELVGRYRELYRKGAY
*:** *** ..*.* *****:****** *:: ::*:** **.** :*.*
Mflv_3795|M.gilvum_PYR-GCK LPAEYRADLACRAAPLLARHGLARAPRFAAPLPGAGPVDAAPELQPTLF-
Mvan_2599|M.vanbaalenii_PYR-1 LPPEYRAELARTVAPLMARHRLAAAPRMAAPAPSVVPVTAG-SLQATLF-
TH_0535|M.thermoresistible__bu LPACYREELQDRVVPLIAKHRLNRRERPLPARPRAAEPAEP--VQPSLFD
Mb2609c|M.bovis_AF2122/97 LPPSYREMLRERVAPLIAKYRLAGDHR--PAPPETEAALV--PVQATLF-
Rv2578c|M.tuberculosis_H37Rv LPPSYREMLRERVAPLIAKYRLAGDHR--PAPPETEAALV--PVQATLF-
MAV_3456|M.avium_104 LPPSYRDMLRHRAAPLIAKYRLGGDHR--PFARAVAAAPAPEPAQPTLF-
MMAR_2148|M.marinum_M LPPYYRDMLRQRVAPLVAKHRLGGTPR--PSSPVAEAEVMPVPEQATLF-
MUL_1734|M.ulcerans_Agy99 LPPYYRDMLRQRVAPLVAKHRLGGTPR--PSSPVAEAEVMPVPEQATLF-
MSMEG_2990|M.smegmatis_MC2_155 LPAEYRHMLHDRVQPLIVKHGLAGQPRMPAPETPTPQVARPEPVQAALF-
MAB_2868c|M.abscessus_ATCC_199 VPAEYRAWLRERVGPLVQKHRLSSHR----EETPTRPVKMAPALEPTLF-
:*. ** * . **: :: * . :.:**