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TAFPDGPVATGGSRCYEVTHRTEYRYSDVVTSSYGRGFLTPRDSARQRCLFHELAIEPDAADSSTSRDVY GNISSYFHVTARHRRLVITSRSVVEVDPPPPDLYQGPSARAPWEIARPVGADGALAKEFTLDLQPPEITE ELRAYAAPSFVAGRPLIEVLRDLNERIYTDFTYRSGSTTVSTQVAEVLAAREGVCQDFARLAIACLRANG LAASYVSGYLATDPPPGKERMVGVDATHAWASVWTPQNLWLGLDPTNNQMVDERYVTVGFGRDYADVPPL RGIIYTDSESSVIDVSVDVAPYLGGVLNA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3769 | - | - | 100% (310) | transglutaminase domain-containing protein |
| M. gilvum PYR-GCK | Mflv_2668 | - | 6e-35 | 34.71% (291) | transglutaminase domain-containing protein |
| M. gilvum PYR-GCK | Mflv_3771 | - | 5e-13 | 28.01% (282) | transglutaminase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2599c | - | 1e-131 | 75.17% (302) | hypothetical protein Mb2599c |
| M. tuberculosis H37Rv | Rv2569c | - | 1e-131 | 75.17% (302) | hypothetical protein Rv2569c |
| M. leprae Br4923 | MLBr_00508 | - | 1e-127 | 74.75% (301) | hypothetical protein MLBr_00508 |
| M. abscessus ATCC 19977 | MAB_2857c | - | 1e-107 | 65.52% (290) | hypothetical protein MAB_2857c |
| M. marinum M | MMAR_2162 | - | 1e-126 | 73.49% (298) | hypothetical protein MMAR_2162 |
| M. avium 104 | MAV_3439 | - | 1e-131 | 76.35% (296) | transglutaminase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3018 | - | 1e-145 | 83.61% (299) | transglutaminase domain-containing protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1746 | - | 1e-125 | 72.82% (298) | hypothetical protein MUL_1746 |
| M. vanbaalenii PYR-1 | Mvan_2630 | - | 1e-165 | 89.68% (310) | transglutaminase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3769|M.gilvum_PYR-GCK ----------------------MTAFPDGPVATGGSRCYEVTHRTEYRYS
Mvan_2630|M.vanbaalenii_PYR-1 ----------------------MTAFPDGPTASGASRCYEITHRTEYRYS
MSMEG_3018|M.smegmatis_MC2_155 ----------------------MTDVFGG----GVTRRYEITHRTVYRYS
Mb2599c|M.bovis_AF2122/97 ----------MSAD---------SSLSLPLSG---THRYRVTHRTEYRYS
Rv2569c|M.tuberculosis_H37Rv ----------MSAD---------SSLSLPLSG---THRYRVTHRTEYRYS
MMAR_2162|M.marinum_M MISLAITGVVAVVDGREVRSQLLSLLSDALFGSPDTKRYRVTHRTEYRYS
MUL_1746|M.ulcerans_Agy99 MISLAITGVVAVVDGREVRSQLLSLLSDALFGSPDTKRYRVTHRTEYRYS
MAV_3439|M.avium_104 -----------------------MPEADQQADGGAARRHRVTHRTEYRYS
MLBr_00508|M.leprae_Br4923 -----------------------MLSCHMKWTQLTSRRYRVSHRTEYRYS
MAB_2857c|M.abscessus_ATCC_199 -----------------------------MTNGLSSIRYQVTHRTLYRYS
: :.::*** ****
Mflv_3769|M.gilvum_PYR-GCK DVVTSSYGRGFLTPRDSARQRCLFHELAIEPDAADSSTSRDVYGNISSYF
Mvan_2630|M.vanbaalenii_PYR-1 DVVTSSYGRGFLTPRDSARQRCLFHELILDPEAADSSISRDGWGNTSSYF
MSMEG_3018|M.smegmatis_MC2_155 DVVTSSYGRGFLTPRGLDRQRCLSHELLIEPEAADSSTSRDAYGNTSSYF
Mb2599c|M.bovis_AF2122/97 DVVTSSYGRGFLTPRNSLRQRCVAHRLTIDPAPADRSTSRDGYGNISSYF
Rv2569c|M.tuberculosis_H37Rv DVVTSSYGRGFLTPRNSLRQRCVAHRLTIDPAPADRSTSRDGYGNISSYF
MMAR_2162|M.marinum_M DIVTSSYGRGFLTPRDSLRQRCVTHQITIDPTPADSSTSRDTYGNISSYF
MUL_1746|M.ulcerans_Agy99 DIVTSSYGRGFLTPRDSLRQRCVTHQITIDPTPADSSTSRDTYGNISSYF
MAV_3439|M.avium_104 DVVTSSYGRGFLTPRDSLRQRCVAHRLTIDPAPADSSTSTDCYGNISSYF
MLBr_00508|M.leprae_Br4923 DVVTSSYGRGFLTPCDSLRQRCVDHRLHIVPVPADSSISRDSYGNISSYF
MAB_2857c|M.abscessus_ATCC_199 DDVTSSYGRGYLTPRDTDWQHCESSELIVEPEPSDRSTGRDLYGNLSSYF
* ********:*** . *:* .: : * .:* * . * :** ****
Mflv_3769|M.gilvum_PYR-GCK HVTARHRRLVITSRSVVEVDPPPPDLYQGPSARAPWEIARPVGAD----G
Mvan_2630|M.vanbaalenii_PYR-1 HVTQRHRALTITSRSVVEVDPPPPDLYDGPSARAPWEIARPVGAD----G
MSMEG_3018|M.smegmatis_MC2_155 HVTTPHRMLCITSHSVVEVDPPAPDHYTCRSAKAPWELARPVGGE----A
Mb2599c|M.bovis_AF2122/97 HVTEPHRTLTITSDSIVDVSPPPPGLYTSGPALQPWEAARPAGLP----G
Rv2569c|M.tuberculosis_H37Rv HVTEPHRTLTITSDSIVDVSPPPPGLYTSGPALQPWEAARPAGLP----G
MMAR_2162|M.marinum_M HVTEPHRVLGITSDSIVDVAPPDSGLYTSGPALLPWEAARPSGMQ----G
MUL_1746|M.ulcerans_Agy99 HVTEPHRVLGITSDSIVDVAPPDSGLYTSGPALLPWEAARPSGMQ----G
MAV_3439|M.avium_104 HVTEPHHSLTVTSDSIVDVNPPAPGLYATGPAVQPWEAARPAGRR----G
MLBr_00508|M.leprae_Br4923 HVTEPHCTLTVTSESIVDVYPTPPELFTSGPASAPWEAARPTGRR----G
MAB_2857c|M.abscessus_ATCC_199 HVTTPHRELSVTARSIVDVENLAP---SGAGWEQPWELARPAYQDSTGAG
*** * * :*: *:*:* . *** *** .
Mflv_3769|M.gilvum_PYR-GCK ALAKEFTLDLQPPEITEELRAYAAPSFVAGRPLIEVLRDLNERIYTDFTY
Mvan_2630|M.vanbaalenii_PYR-1 ALATEFTLDLQPSEITEEIRAYAAPSFVAGRPLIEVLLDLTQRIYTDFTY
MSMEG_3018|M.smegmatis_MC2_155 ALAAEFTLDLQPPEITDAVREYAAPSFEPGRPLIEVLRDLTSRIYTDFTY
Mb2599c|M.bovis_AF2122/97 SLATEFTLDLNPPEITDAVREYAAPSFLPKRPLVEVLRDLASRIYTDFTY
Rv2569c|M.tuberculosis_H37Rv SLATEFTLDLNPPEITDAVREYAAPSFLPKRPLVEVLRDLASRIYTDFTY
MMAR_2162|M.marinum_M ALAVDFALDLDPAEITDEVREYAAVSFLPERPLVEALRDLTTRIYNDFTY
MUL_1746|M.ulcerans_Agy99 ALAVDFALDLDPAEITDEVREYGAVSFLPERPLVEALRDLTTRIYNDFTY
MAV_3439|M.avium_104 ALATEFTLDLDPPEITDEVRDYAAPSFAPGRPLIEVLRDLASRIFTDFTY
MLBr_00508|M.leprae_Br4923 VLATEFTLDLNPPEITDEVRQYAAPSFEPQRPLIEVLRDLTTRIYADFTY
MAB_2857c|M.abscessus_ATCC_199 ALATEFVLDLVPPEITDDVRDYAAVSFTPGRPLGEAVVDLMGRIYRDFEY
** :*.*** *.***: :* *.* ** . *** *.: ** **: ** *
Mflv_3769|M.gilvum_PYR-GCK RSGSTTVSTQVAEVLAAREGVCQDFARLAIACLRANGLAASYVSGYLATD
Mvan_2630|M.vanbaalenii_PYR-1 RSGSTTVSTKVSEVLAAREGVCQDFARLAIACLRANGLAASYASGYLATD
MSMEG_3018|M.smegmatis_MC2_155 RSGSTTISTQVAEVLAAREGVCQDFARLAIACLRANGLAASYVSGYLATD
Mb2599c|M.bovis_AF2122/97 RSGSTTISTGVNEVLLAREGVCQDFARLAIACLRANGLAACYVSGYLATD
Rv2569c|M.tuberculosis_H37Rv RSGSTTISTGVNEVLLAREGVCQDFARLAIACLRANGLAACYVSGYLATD
MMAR_2162|M.marinum_M RSGSTTVSTRVNEVLQAREGVCQDFARLAIACLRANGLAACYVSGYLATD
MUL_1746|M.ulcerans_Agy99 RSGSTTVSTRVNEVLQAREGVCQDFARLAIACLRANGLAACYVSGFLATD
MAV_3439|M.avium_104 RSGSTTISTGVAEVLAAREGVCQDFARLAIACLRAHGLAASYVSGYLATD
MLBr_00508|M.leprae_Br4923 RSGSTTISTGVNEVLLAREGVCQDFARLAIACLRANGLAASYVSGYLATD
MAB_2857c|M.abscessus_ATCC_199 RSGSTTISTKVSEVLAAREGVCQDFARIAATALRTQGLAARYVSGYLATN
******:** * *** ***********:* :.**::**** *.**:***:
Mflv_3769|M.gilvum_PYR-GCK PPPGKERMVGVDATHAWASVWTPQN----LWLGLDPTNNQMVDERYVTVG
Mvan_2630|M.vanbaalenii_PYR-1 PPPGKERMVGIDATHAWASVWTPQN----LWLGLDPTNNQMVDERYVTVG
MSMEG_3018|M.smegmatis_MC2_155 PPPGRERMVGVDATHAWASVWTPQN----IWLGLDPTNDQMVDERYIVAG
Mb2599c|M.bovis_AF2122/97 PPPGKDRMIGIDATHAWASVWTPQQPGRFEWLGLDPTNDQLVDQRYIVVG
Rv2569c|M.tuberculosis_H37Rv PPPGKDRMIGIDATHAWASVWTPQQPGRFEWLGLDPTNDQLVDQRYIVVG
MMAR_2162|M.marinum_M PPPGKDRMIGIDATHAWAAVWTPQQPGQFEWMGLDPTNDQLVDERYIVVG
MUL_1746|M.ulcerans_Agy99 PPPGKDRMIGIDATHAWAAVWTPQQPGQFEWMGLDPTNDQLVDERYIVVG
MAV_3439|M.avium_104 PPPGKDRMIGIDATHAWAAVWTPHEPGQFEWLGVDPTNDQMIDERYIVVG
MLBr_00508|M.leprae_Br4923 PPPGKDRMVGIDVTHAWASVWTPQQSGQCEWLGLDPTNDQLVDERYIVVG
MAB_2857c|M.abscessus_ATCC_199 PPPGQPRLVGSDATHAWAAVWVPPD----GWIAFDPTNDTIADQRYVTVA
****: *::* *.*****:**.* : *:..****: : *:**:...
Mflv_3769|M.gilvum_PYR-GCK FGRDYADVPPLRGIIYTDSESSVIDVSVDVAPYLGGVLNA
Mvan_2630|M.vanbaalenii_PYR-1 LGRDYADIPPLRGIIYTDSESSTIDVSVDVAPYAGGVLRA
MSMEG_3018|M.smegmatis_MC2_155 FGRDYADVPPLRGIIYTDSESSVIEVSVDVAPYEGDLLHA
Mb2599c|M.bovis_AF2122/97 RGRDYADVPPLRGIIYTNSENSVIDVSVDVVPFEGDALHA
Rv2569c|M.tuberculosis_H37Rv RGRDYADVPPLRGIIYTNSENSVIDVSVDVVPFEGDALHA
MMAR_2162|M.marinum_M RGRDYADVPPVRGIIYTNSEHSVIDVGVDVVPFDGDVLDA
MUL_1746|M.ulcerans_Agy99 RGRDYADVPPVRGIIYTNSEHSVIDVGVDVVPFEGDVLDA
MAV_3439|M.avium_104 RGRDYADVPPLRGIIYTNSQHSVIDVSVDVVPYA------
MLBr_00508|M.leprae_Br4923 QGRDYVNVPPLRGIIYTNSENSVIDVAVDVAPCEGDALYA
MAB_2857c|M.abscessus_ATCC_199 WGRDYADVPPLRGIIYTDSDSSSIEVSVDVAPCEESPAHA
****.::**:******:*: * *:*.***.*