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NEHHGRHEMPPDAAPEAPRRRRSVFGVLAVLLCLLLGVAIATQVRQTDSGDSLETARPADLLVLLDSLQQ REAALNTEVADLQRTLTQLETSGSSDQAAIENARARLAALSILIGSIAATGPGVILTVTDPAQGVAAETM LDVINELRAAGAEAMEIRGRSGGGDQVAVRVGVDTWVTGGPGALVVDETTLAPAYSVLAIGDPPTLAAAM NIPGGAMDSIERVGGTMTVQQSERVDVTALRQPKPRQYAQPVK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3404 | - | - | 100% (254) | hypothetical protein Mflv_3404 |
| M. gilvum PYR-GCK | Mflv_3406 | - | 4e-09 | 30.57% (229) | hypothetical protein Mflv_3406 |
| M. gilvum PYR-GCK | Mflv_0814 | - | 6e-08 | 24.76% (206) | hypothetical protein Mflv_0814 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1856 | - | 4e-92 | 66.92% (263) | hypothetical protein Mb1856 |
| M. tuberculosis H37Rv | Rv1825 | - | 4e-92 | 66.92% (263) | hypothetical protein Rv1825 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2401 | - | 9e-91 | 64.57% (254) | hypothetical protein MAB_2401 |
| M. marinum M | MMAR_2702 | - | 8e-92 | 72.65% (234) | hypothetical protein MMAR_2702 |
| M. avium 104 | MAV_2890 | - | 3e-91 | 64.39% (264) | hypothetical protein MAV_2890 |
| M. smegmatis MC2 155 | MSMEG_3649 | - | 1e-106 | 75.38% (264) | hypothetical protein MSMEG_3649 |
| M. thermoresistible (build 8) | TH_1124 | - | 1e-102 | 75.00% (252) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3044 | - | 3e-95 | 68.82% (263) | hypothetical protein MUL_3044 |
| M. vanbaalenii PYR-1 | Mvan_3137 | - | 1e-119 | 86.90% (252) | hypothetical protein Mvan_3137 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1856|M.bovis_AF2122/97 MSEN-----RPEPVAAETSAATTARHSQADAGAHDAVRRGRHELPADHPR
Rv1825|M.tuberculosis_H37Rv MSEN-----RPEPVAAETSAATTARHSQADAGAHDAVRRGRHELPADHPR
MMAR_2702|M.marinum_M -------------------------------------------MPADRSR
MUL_3044|M.ulcerans_Agy99 MSQDCCAAGGDESRDENRGTATQHGHSKTTPKSHATAKHGRHEMPADRSR
MAV_2890|M.avium_104 -----------------MNMSHDPPDRPADP-PDQGAAHGRHELPGKQPR
Mflv_3404|M.gilvum_PYR-GCK ----------------------------------MNEHHGRHEMPPD---
Mvan_3137|M.vanbaalenii_PYR-1 ----------------------------------MSEH-GRHELPPDDG-
MSMEG_3649|M.smegmatis_MC2_155 -------------------MTENPENPTAAPTGRGAEHHGRHEMPEPTSR
TH_1124|M.thermoresistible__bu -----------MAGGPATGPRDEDRKATAAPAAGSGPRHGRHEMPSGAG-
MAB_2401|M.abscessus_ATCC_1997 --------MLPPCGAGCLGREPVNQSHPGQPDPRLESHPGKHEMPKTRR-
:*
Mb1856|M.bovis_AF2122/97 SKVGPLRRTRLTEILRGGRSRLVFGTLAILLCLVLGVAIVTQVRQTDSGD
Rv1825|M.tuberculosis_H37Rv SKVGPLRRTRLTEILRGGRSRLVFGTLAILLCLVLGVAIVTQVRQTDSGD
MMAR_2702|M.marinum_M PDRGP-RETQDSTGARRGRSRLLFGALAILLCLVLGVAIVTQVRQTESGD
MUL_3044|M.ulcerans_Agy99 PDRGP-RETQDSTGARRGRSRLLFGALAILLCLVLGVAIVTQVRQTESGD
MAV_2890|M.avium_104 PAIGPLRRTGLSGMLRGGRSRFGFGTLAVLLCLLLGIAIVTQVRQTESGD
Mflv_3404|M.gilvum_PYR-GCK -----------AAPEAPRRRRSVFGVLAVLLCLLLGVAIATQVRQTDSGD
Mvan_3137|M.vanbaalenii_PYR-1 -----------AAPARGGRSQAVFGVLAVLLCLLLGVAIATQVRQTDSGD
MSMEG_3649|M.smegmatis_MC2_155 FRMFK----RDPAAAPKTRSQLMFGALGVLLCLLLGVAIVTQVRQNESGD
TH_1124|M.thermoresistible__bu -----------PFPAGRRGQRLLFGALAVLLCLLLGVAIVTQVRQNESDD
MAB_2401|M.abscessus_ATCC_1997 ---------------PPTRSQITFGVLGVALCALLGLAITTQVRQTESGD
: **.*.: ** :**:**.*****.:*.*
Mb1856|M.bovis_AF2122/97 SLETARPADLLVLLDSLRQREATLNAEVIDLQNTLNALQASGNTDQAALE
Rv1825|M.tuberculosis_H37Rv SLETARPADLLVLLDSLRQREATLNAEVIDLQNTLNALQASGNTDQAALE
MMAR_2702|M.marinum_M SLETARPADLLVLLDSLRQREGTLNAEVTDLQNTLNALEASGNNDQTAIE
MUL_3044|M.ulcerans_Agy99 SLETARPADLLVLLDSLRQREGTLNAEVTDLQNTLNALEASGNNDQAAIE
MAV_2890|M.avium_104 SLETARPADLLVLLDSLRQREGTLSAEVSELQNTLNSLQASGNNDQAAIQ
Mflv_3404|M.gilvum_PYR-GCK SLETARPADLLVLLDSLQQREAALNTEVADLQRTLTQLETSGSSDQAAIE
Mvan_3137|M.vanbaalenii_PYR-1 SLETARPADLLVLLDSLQQREAALNTEVADLQRTLTQLQASGSSDQAAIE
MSMEG_3649|M.smegmatis_MC2_155 SLETARPADLLVLLDSLQQREASLNTEVADLRRTLQELQASGSSDQAAIE
TH_1124|M.thermoresistible__bu ALQTARPADLLVLLDSLQQREAALNTEIADLQRTLAALEASGSSDEAAIE
MAB_2401|M.abscessus_ATCC_1997 GLDTARPADLLVLLDSLQQREANLNKEIADLQQSLITMRASGTGNQAVIN
.*:**************:***. *. *: :*:.:* :.:**. :::.::
Mb1856|M.bovis_AF2122/97 SAQARLAALSILVGAVGATGPGVMITIDDPGPGVAPEVMIDVINELRAAG
Rv1825|M.tuberculosis_H37Rv SAQARLAALSILVGAVGATGPGVMITIDDPGPGVAPEVMIDVINELRAAG
MMAR_2702|M.marinum_M SAQARLAALSILVGAVGATGPGVTVRIDDPGPGVAPEAMLDVINELRAAG
MUL_3044|M.ulcerans_Agy99 SAQARLAALSILVGAVGATGPGVTVRIDDPGPGVAPEAMLDVINELRAAG
MAV_2890|M.avium_104 SAQSRLAALSILVGAVGATGPGVTVTIDDPAPGVSPEALLDVVNELRAAG
Mflv_3404|M.gilvum_PYR-GCK NARARLAALSILIGSIAATGPGVILTVTDPAQGVAAETMLDVINELRAAG
Mvan_3137|M.vanbaalenii_PYR-1 NAQARLAALSILIGTVAATGPGVTMTITDPAQGVAAETMLDVINELRAAG
MSMEG_3649|M.smegmatis_MC2_155 NAQARLAALSIQIGTVAATGPGVTLTITDTGPGVSAETMLDVINELRAAG
TH_1124|M.thermoresistible__bu NAQERLAALSIMIGTVAATGPGVILTIDDTAPGVSPETMVDVINELRNAG
MAB_2401|M.abscessus_ATCC_1997 DAKARLSALSIMVGTVGATGPGVILTINDPGQGLGPEALLDIVNELRAAG
.*: **:**** :*::.****** : : *.. *:..*.::*::**** **
Mb1856|M.bovis_AF2122/97 AEAIQIND-----AHRSVRVGVDTWVVGVPGSLTVDTKVLSPPYSILAIG
Rv1825|M.tuberculosis_H37Rv AEAIQIND-----AHRSVRVGVDTWVVGVPGSLTVDTKVLSPPYSILAIG
MMAR_2702|M.marinum_M AEAIQVSD-----AQQSVRVGVDTWVVGAPGALTIDNKNLSPPYSILAIG
MUL_3044|M.ulcerans_Agy99 AEAIQVSD-----AQQSVRVGVDTWVVGAPGALTTDNKNLSPPYSILAIG
MAV_2890|M.avium_104 AEALEVND-----AHQSVRVGVDTWVAGTPGSLTIDSKTLSPSYSILAIG
Mflv_3404|M.gilvum_PYR-GCK AEAMEIRGRSGGGDQVAVRVGVDTWVTGGPGALVVDETTLAPAYSVLAIG
Mvan_3137|M.vanbaalenii_PYR-1 AEAMEIRGEQGG-QQVSVRIGVDTWVVGGPGALVIDSATVGPVYSVLAIG
MSMEG_3649|M.smegmatis_MC2_155 AEAIEIRG--GGDQQTAVRVGVDTWIAGTPGELIFDDVTVRPPYSVLAIG
TH_1124|M.thermoresistible__bu AEAIEIRG--GGPDGPAARIGVDSWVAGAPGTLIVDDATLTPPYAVSAIG
MAB_2401|M.abscessus_ATCC_1997 AEAIEITA-----GDKSVRIGVDSWIIGAPGQLVVDGTTLTPPYSVLAIG
***::: :.*:***:*: * ** * * : * *:: ***
Mb1856|M.bovis_AF2122/97 DPPTLAAAMNIPGGAQDGVKRVGGRMVVQQADRVDVTALRQPKQHQYAQP
Rv1825|M.tuberculosis_H37Rv DPPTLAAAMNIPGGAQDGVKRVGGRMVVQQADRVDVTALRQPKQHQYAQP
MMAR_2702|M.marinum_M DPPTLAAAMNIPGGAEDSIKRVGGRMSVQQSDRVDVTALRQPKPHQYAQP
MUL_3044|M.ulcerans_Agy99 DPPTLAAAMNIPGGAEDSIKRVGGRMSVQQSDRVDVTALRQPKPHQYAQP
MAV_2890|M.avium_104 DPPTLAAAMNIPGGAQDTVKRVGGRMSVQQADRVDVTTLRQPKPHQYAQP
Mflv_3404|M.gilvum_PYR-GCK DPPTLAAAMNIPGGAMDSIERVGGTMTVQQSERVDVTALRQPKPRQYAQP
Mvan_3137|M.vanbaalenii_PYR-1 DPPTLAAAMNIPGGAMDSIERVGGTMVVQQSDRVDVTALRQPKPRQYAQP
MSMEG_3649|M.smegmatis_MC2_155 DPPTLAAAMNIPGGAMDSVKRVGGTMVIQQAEQVDVTALRQPKPRQYAQP
TH_1124|M.thermoresistible__bu DPPTLAAAMTIPGGAMDAVERVGGRMRIEQAERVDVTALRQPKPRQYAQP
MAB_2401|M.abscessus_ATCC_1997 DPPTLAAAMNIPGGAVDTVSRVGGSVTIDQPARVDITTLREPKPRQYAQP
*********.***** * :.**** : ::*. :**:*:**:** :*****
Mb1856|M.bovis_AF2122/97 VK
Rv1825|M.tuberculosis_H37Rv VK
MMAR_2702|M.marinum_M VK
MUL_3044|M.ulcerans_Agy99 VK
MAV_2890|M.avium_104 VK
Mflv_3404|M.gilvum_PYR-GCK VK
Mvan_3137|M.vanbaalenii_PYR-1 VK
MSMEG_3649|M.smegmatis_MC2_155 VK
TH_1124|M.thermoresistible__bu VK
MAB_2401|M.abscessus_ATCC_1997 GK
*