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GEQSGHPVRRPALSPSRAGDFKQCPLLYRFRAIDRLPEPSSTAQVRGSVVHAALEQLYALPAAERRPETA LSLVAPAWERVVAEQPSLATDIDPALRAEMLEQARTLLSGYYRLEDPTRFDPQSCEQRVEVELADGTLLR GFIDRIDVAPTGEMRVVDYKTGKAPPEARALAEFKAMFQMKFYAVALLRSRGSLPARLRLVYLADHQILD YTPTLDELERFEKTLMAIWRAIQSAGATGDFRPSPSRLCNWCAHQAHCPSFGGTPPPYPGWPQVLDDGDP DAVLQAEPAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3064 | - | - | 100% (291) | RecB family exonuclease |
| M. gilvum PYR-GCK | Mflv_4666 | - | 2e-05 | 27.01% (274) | UvrD/REP helicase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2143 | - | 1e-124 | 77.66% (273) | hypothetical protein Mb2143 |
| M. tuberculosis H37Rv | Rv2119 | - | 1e-124 | 77.66% (273) | hypothetical protein Rv2119 |
| M. leprae Br4923 | MLBr_01312 | - | 1e-115 | 74.14% (263) | hypothetical protein MLBr_01312 |
| M. abscessus ATCC 19977 | MAB_2155c | - | 1e-112 | 70.91% (275) | hypothetical protein MAB_2155c |
| M. marinum M | MMAR_3095 | - | 1e-123 | 79.85% (263) | hypothetical protein MMAR_3095 |
| M. avium 104 | MAV_2395 | - | 1e-124 | 77.57% (272) | RecB family protein exonuclease |
| M. smegmatis MC2 155 | MSMEG_3907 | - | 1e-125 | 76.60% (282) | RecB family protein exonuclease |
| M. thermoresistible (build 8) | TH_0043 | - | 1e-111 | 76.83% (246) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2341 | - | 1e-122 | 79.47% (263) | hypothetical protein MUL_2341 |
| M. vanbaalenii PYR-1 | Mvan_3463 | - | 1e-145 | 85.42% (288) | RecB family exonuclease |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2143|M.bovis_AF2122/97 MAD---------QPDPPTPRPALSPSRATDFKQCPLLYRFRAIDRLPEAT
Rv2119|M.tuberculosis_H37Rv MAD---------QPDPPTPRPALSPSRATDFKQCPLLYRFRAIDRLPEAT
Mflv_3064|M.gilvum_PYR-GCK MGE---------QSGHPVRRPALSPSRAGDFKQCPLLYRFRAIDRLPEPS
Mvan_3463|M.vanbaalenii_PYR-1 MSDRRPSLDHMSEPTRPVRRPALSPSRASDFKQCPLLYRFRAIDRLPEPS
MSMEG_3907|M.smegmatis_MC2_155 MSEEP------VRGAAGRRRPALSPSRASDFKQCPLLYRFRAIDRLPEPR
MAB_2155c|M.abscessus_ATCC_199 MSET--------TRDRPVRRPALSPSRASDFKQCPLLYRLRAIDRLPEPP
TH_0043|M.thermoresistible__bu ------------------------------------LYRFRAIDRLPEPT
MAV_2395|M.avium_104 MIVQPEARQSAARPAGQVSRPALSPSRAADFKQCPLLYRFRAIDRLPEAP
MMAR_3095|M.marinum_M MTDQP------GSVASVYIRPALSPSRAADFKQCPLLYRFRAIDRLPEKP
MUL_2341|M.ulcerans_Agy99 MTDQP------GSVASVYIRPALSPSRAADFKQCPLLYRFRAIDRLSEKP
MLBr_01312|M.leprae_Br4923 MIDQPKP----LRADLCSPRLALSPSRAADFKQCPLLYRFRAIDRLPEAP
***:******.*
Mb2143|M.bovis_AF2122/97 SAAQLRGSVVHAALEQLYGLPAGLRSPDTARSLVQRAWDQMVAAEPELAG
Rv2119|M.tuberculosis_H37Rv SAAQLRGSVVHAALEQLYGLPAGLRSPDTARSLVQRAWDQMVAAEPELAG
Mflv_3064|M.gilvum_PYR-GCK STAQVRGSVVHAALEQLYALPAAERRPETALSLVAPAWERVVAEQPSLAT
Mvan_3463|M.vanbaalenii_PYR-1 SAAQVRGTVVHAALEQLYRLPAVERGPATAAALVAPVWERLLAEQPSLAV
MSMEG_3907|M.smegmatis_MC2_155 STAQLRGTLVHAALEDLYGLPAQERVPDTALSLVEPAWDRVVAADPELAS
MAB_2155c|M.abscessus_ATCC_199 SAAQARGSLVHAALEDLYTRPAAEREYATAAGLVEPAWERLVESNPELAE
TH_0043|M.thermoresistible__bu SPAQVRGSVVHAALEQLYALPAAQRDRDTALGLIGPAWEQVLARQPELAA
MAV_2395|M.avium_104 SPAQLRGSLVHAALQQLYELPAAQRGPETALALVGPAWEQLLAATPELTA
MMAR_3095|M.marinum_M STAQLRGSVVHAALEQLYALPAVQRGPDTARSLVESAWEQVIAGELDLAG
MUL_2341|M.ulcerans_Agy99 STAQLRGSVVHAALEQLYALPAVQRGPDTARSLVESAWEQVIAGELDLAG
MLBr_01312|M.leprae_Br4923 SAAQLLGSVVHTTLQRLYGLPALRRCSDTARSLVESVWNQMIAAERDLDG
*.** *::**::*: ** ** * ** .*: .*:::: .*
Mb2143|M.bovis_AF2122/97 ELDPGQPTQLLEDARALVSGYYRLEDPTRFDPQCCEQRVEVELADGTLLR
Rv2119|M.tuberculosis_H37Rv ELDPGQPTQLLEDARALVSGYYRLEDPTRFDPQCCEQRVEVELADGTLLR
Mflv_3064|M.gilvum_PYR-GCK DIDPALRAEMLEQARTLLSGYYRLEDPTRFDPQSCEQRVEVELADGTLLR
Mvan_3463|M.vanbaalenii_PYR-1 DIEPALHGELLEQARALLSGYYRLEDPTRFDPQSCEQRVEVELVDGTLLR
MSMEG_3907|M.smegmatis_MC2_155 ---LAERDVLLREARALLTGYYRLEDPTRFDPQCCEQLIEVELADGTLLR
MAB_2155c|M.abscessus_ATCC_199 VVEAERLPRFFDEARDLLSGYYRLEDPTRFDPDSCEERVEVELADGTMLR
TH_0043|M.thermoresistible__bu EWADPQRADLFAEARSLVSGYYRLEDPTRFDPHACEEFVEVELADGTLLR
MAV_2395|M.avium_104 DLDPTQHGQLLAEAQALLAGYYRLEDPTRFDPQCCEERVEVELADGTLLR
MMAR_3095|M.marinum_M ELAADQQAQLLEDARALLSGYYRLEDPRRFDPQSCEQRVEVELADGTLLR
MUL_2341|M.ulcerans_Agy99 ELAADQQAQLLEDARALLSGYYRLEDPRRFDPQSCEQRVEVELADGTLLR
MLBr_01312|M.leprae_Br4923 ELDAKQRTQLLDEARTLLSGYYRLEDPTRFNPQSCEQRVEVELADGLLLR
:: :*: *::******** **:*..**: :****.** :**
Mb2143|M.bovis_AF2122/97 GYIDRIDVAATGELRVVDYKTGKAPPAARALAEFKAMFQMKFYAVALFRS
Rv2119|M.tuberculosis_H37Rv GYIDRIDVAATGELRVVDYKTGKAPPAARALAEFKAMFQMKFYAVALFRS
Mflv_3064|M.gilvum_PYR-GCK GFIDRIDVAPTGEMRVVDYKTGKAPPEARALAEFKAMFQMKFYAVALLRS
Mvan_3463|M.vanbaalenii_PYR-1 GYVDRIDVAPTGEVRVVDYKTGKAPPEARALAEFKAMFQMKFYAVALLRS
MSMEG_3907|M.smegmatis_MC2_155 GYVDRIDVAPTGEVRVVDYKTGKAPAAARELAEFKALFQMKFYAVALLRS
MAB_2155c|M.abscessus_ATCC_199 GFIDRIDIAPGGAMRLVDYKTGRAP---RALFEAKALFQMKFYAVALYRT
TH_0043|M.thermoresistible__bu GFIDRIDLAPTGELRVVDYKTGKAPPAARAVAEAKALFQMKFYAVAVLRS
MAV_2395|M.avium_104 GFIDRIDVAATGELRVVDYKTGKAPPAARALAEFKAMFQMKFYAVALLRS
MMAR_3095|M.marinum_M GYIDRIDVAATGELRVVDYKTGKAPPAARALAEFKAMFQMKFYGVALFRS
MUL_2341|M.ulcerans_Agy99 GYIDRIDVAATGELRVVDYKTGKAPPAARALAEFKAMFQMKFYGVALFRS
MLBr_01312|M.leprae_Br4923 GFIDRIDVAATGELRVVDYKTGKAPPAAQALAEFKAMFQMKFYALTLLHS
*::****:*. * :*:******:** : : * **:******.::: ::
Mb2143|M.bovis_AF2122/97 RGVPPTRLRLIYLADGQLLDYSPDRDELLRFEKTLMAIWRAIQSAGETGD
Rv2119|M.tuberculosis_H37Rv RGVPPTRLRLIYLADGQLLDYSPDRDELLRFEKTLMAIWRAIQSAGETGD
Mflv_3064|M.gilvum_PYR-GCK RGSLPARLRLVYLADHQILDYTPTLDELERFEKTLMAIWRAIQSAGATGD
Mvan_3463|M.vanbaalenii_PYR-1 RGVLPSRLRLLYLADGQVLDYSPDLEELERFEKTLMAIWRAIQSAGATGD
MSMEG_3907|M.smegmatis_MC2_155 REVMPSRLRLLYLADKQVLDYSPAHDELLRFERTLIAIWKAIQAAGAGGD
MAB_2155c|M.abscessus_ATCC_199 RGVVPRRLRLLYLSDGEVLDYAPDEAELLKFEKTLMAIWRAIQNIGTTGD
TH_0043|M.thermoresistible__bu RGVLPARLRLIYLADGQLLDYSPDHDELLRFERTLMAIWRAIQKAGADRD
MAV_2395|M.avium_104 RGVPPTRLRLIYLADGQVLDYSPEYDELLRFEKTLMAIWRAIQSAGRTGD
MMAR_3095|M.marinum_M RGVLPSRLRLIYLADGQVLDYSPDRDELLRFEKTLMAIWRAIQSAGQSGD
MUL_2341|M.ulcerans_Agy99 RGVLPSRLRLIYLADGQVLDYSPDRDELLRFEKTLMAIWRAIQSAGQSGD
MLBr_01312|M.leprae_Br4923 RGVLPARLRLIYLADSQLLDYAPDRDELLRFGKTLMAIWRTIQFSGETGD
* * ****:**:* ::***:* ** :* :**:***::** * *
Mb2143|M.bovis_AF2122/97 FRPNPSRLCDWCPHQQRCPAFGGTPPPYPGWPTEPAA-------------
Rv2119|M.tuberculosis_H37Rv FRPNPSRLCDWCPHQQRCPAFGGTPPPYPGWPTEPAA-------------
Mflv_3064|M.gilvum_PYR-GCK FRPSPSRLCNWCAHQAHCPSFGGTPPPYPGWPQVLDD----GDPDAVLQA
Mvan_3463|M.vanbaalenii_PYR-1 FRPNPSKLCDWCAHRVHCPTFGGTPPPYPGWPEVLDETLEDGDPDAVLHA
MSMEG_3907|M.smegmatis_MC2_155 FRPNPSRLCSWCAHQSLCPAFGGTLPPYPGWPDQIDD----GDPDAVLQE
MAB_2155c|M.abscessus_ATCC_199 FRPNPSRLCDWCAHQSLCPAFGGTPPPYPGWPADYGVADADIEDTATSIS
TH_0043|M.thermoresistible__bu FRPNASKLCDWCVHRAHCPVFGGTPPPYPGWPAEIAA-------------
MAV_2395|M.avium_104 FRPTQSRLCDWCPHQQLCPLFGGTPPPYPGWPDTLGAQ----DNSTLSDP
MMAR_3095|M.marinum_M FRPNASRLCNWCPHQQHCPAYGGTPPPYPGWPDRPPG-----EAVSCSAI
MUL_2341|M.ulcerans_Agy99 FRPNASRLCNWCPHQQHCPAYGGTPPPYPGWPDRPPA-----EAVSCSAI
MLBr_01312|M.leprae_Br4923 FRPNPSRLCGWCPHQEHCPAFGGTPPPYPGWPDHSHT------EAVSRLT
***. *:**.** *: ** :*** *******
Mb2143|M.bovis_AF2122/97 -----
Rv2119|M.tuberculosis_H37Rv -----
Mflv_3064|M.gilvum_PYR-GCK EPAA-
Mvan_3463|M.vanbaalenii_PYR-1 EPAA-
MSMEG_3907|M.smegmatis_MC2_155 VGAA-
MAB_2155c|M.abscessus_ATCC_199 GDAA-
TH_0043|M.thermoresistible__bu -----
MAV_2395|M.avium_104 VDLAG
MMAR_3095|M.marinum_M EPTA-
MUL_2341|M.ulcerans_Agy99 EPTA-
MLBr_01312|M.leprae_Br4923 ESAA-