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VSARGLKLVALSLLLGGMTVLLSGCSWSEVLGLGWPNGITPEAHANRELWIGSVIAAFVVGGIVYVLTFW TTIFHRKKATDTELPRQFGYNMPLELTLTVIPFIIISVLFYFTVVVQEEMLKKEPNPEVVIDVTAFQWNW KFGYQKVEFADGTMSYDGVDNERKEAMTSAPEGADEHGIEQIGAIAGKRPEDRTYLNFDKIETLGSSTEI PVLVVPSGKRIEFQIASADVIHGFWVPEFLFKRDVLPNPKENNSDNIFQVSEIMQTGAFVGRCTEMCGTY HAMMNFELRVVEPNDFKAYLAQREAGKTNAEALRAINQEPLAVTTKPFDTRRGELAPQVPAATR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2949 | - | - | 100% (344) | cytochrome c oxidase, subunit II |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2223c | ctaC | 1e-153 | 75.30% (336) | transmembrane cytochrome C oxidase subunit II CtaC |
| M. tuberculosis H37Rv | Rv2200c | ctaC | 1e-153 | 75.30% (336) | transmembrane cytochrome C oxidase subunit II CtaC |
| M. leprae Br4923 | MLBr_00875 | ctaC | 1e-145 | 71.47% (333) | putative cytochrome C oxidase chain II |
| M. abscessus ATCC 19977 | MAB_1961 | - | 1e-134 | 68.58% (331) | cytochrome c oxidase subunit 2 precursor |
| M. marinum M | MMAR_3244 | ctaC | 1e-144 | 72.81% (331) | transmembrane cytochrome C oxidase (subunit II) CtaC |
| M. avium 104 | MAV_2291 | - | 1e-142 | 71.39% (332) | cytochrome c oxidase, subunit 2 |
| M. smegmatis MC2 155 | MSMEG_4268 | - | 1e-164 | 80.18% (338) | cytochrome c oxidase subunit 2 |
| M. thermoresistible (build 8) | TH_2397 | ctaC | 1e-149 | 75.84% (327) | PROBABLE TRANSMEMBRANE CYTOCHROME C OXIDASE (SUBUNIT II) |
| M. ulcerans Agy99 | MUL_3557 | ctaC | 1e-143 | 72.51% (331) | transmembrane cytochrome C oxidase (subunit II) CtaC |
| M. vanbaalenii PYR-1 | Mvan_3564 | - | 1e-178 | 86.92% (344) | cytochrome c oxidase, subunit II |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2949|M.gilvum_PYR-GCK -------------------------MSARGLKLVA-LSLLLGGMTVLLSG
Mvan_3564|M.vanbaalenii_PYR-1 -------------------------MSARGLKLVA-LSLLLGGTTVLLSG
MSMEG_4268|M.smegmatis_MC2_155 -------------------------MTPRGFRVVA-LSIVLGGSALLLSG
TH_2397|M.thermoresistible__bu -------------------------------------------MALLLSG
MMAR_3244|M.marinum_M MTPREPGRSQSLSPCNSQSNSVGRSGAARRIARLAGLAGALGLLAVTLSG
MUL_3557|M.ulcerans_Agy99 MTPREPGRSQSLSPCNSQSNSVGRSGAARRIARLAGLAGALGLLAVTLSG
Mb2223c|M.bovis_AF2122/97 MTPRGPGRLQRLSQCRPQR---GSGGPARGLRQLA-LAAMLGALAVTVSG
Rv2200c|M.tuberculosis_H37Rv MTPRGPGRLQRLSQCRPQR---GSGGPARGLRQLA-LAAMLGALAVTVSG
MLBr_00875|M.leprae_Br4923 MTARELVCSQRVG-----------QGLSRRLRPLV-LAVTLGVLVVTLSG
MAV_2291|M.avium_104 -----------------------------MLRPLA-LAVTLGVLAIVLSG
MAB_1961|M.abscessus_ATCC_1997 -----------------------MTSRSGSRPSLLATVVLLGAASFLLSG
. :**
Mflv_2949|M.gilvum_PYR-GCK CS-WSEVLGLGWPNGITPEAH-ANRELWIGSVIAAFVVGGIVYVLTFWTT
Mvan_3564|M.vanbaalenii_PYR-1 CS-WSEVLGLGWPNGITPEAH-LNRELWIGSVIAALVVGAIVYVLLFWTM
MSMEG_4268|M.smegmatis_MC2_155 CS-WSDALALGWPTGITPEAK-LNRELWIGSVIASFAVGAIVWGLIFWTS
TH_2397|M.thermoresistible__bu CS-WSDVLGLGWPKGITPEAH-VNRELWIGSVIASLVVGAIVWGLTFWTC
MMAR_3244|M.marinum_M CS-WSEALALGWPEGITPEAH-VNRELWIGAVIASLVVGVIVWGLIFWSA
MUL_3557|M.ulcerans_Agy99 CS-WSEALALGWPEGITPEAH-VNRELWIGAVIASLVVGVIVWGLIFWSA
Mb2223c|M.bovis_AF2122/97 CS-WSEALGIGWPEGITPEAH-LNRELWIGAVIASLAVGVIVWGLIFWSA
Rv2200c|M.tuberculosis_H37Rv CS-WSEALGIGWPEGITPEAH-LNRELWIGAVIASLAVGVIVWGLIFWSA
MLBr_00875|M.leprae_Br4923 CS-WSDALAIGWPEGITPEAH-LNRQLWIGAVVASLVVGVIVWGLIFWST
MAV_2291|M.avium_104 CSSWADALALGWPKGITPQAH-LNRELWIGAVIASLVVGAIVYGLIFWAS
MAB_1961|M.abscessus_ATCC_1997 CS-VQEVLRFGWPEGITPEAHDYMAPLWTWAVVASLVVGVIVWGLTFWTV
** :.* :*** ****:*: ** :*:*::.** **: * **:
Mflv_2949|M.gilvum_PYR-GCK IFHRKKATDTELPRQFGYNMPLELTLTVIPFIIISVLFYFTVVVQEEMLK
Mvan_3564|M.vanbaalenii_PYR-1 AFHRKKKGDTELPRQFGYNMPLELTLTVIPFIIISVLFYFTVVVQEKMVH
MSMEG_4268|M.smegmatis_MC2_155 AFHRKKATDTELPRQFGYNMPLELTLTVIPFLIISVLFYFTVVVQERMMH
TH_2397|M.thermoresistible__bu AFHRKKKGDTELPRQFGYNMPLELVLTVTPFLIISVLFYFTVVVQERMLH
MMAR_3244|M.marinum_M TFHRKKKTDTDFPRQFGYNMPLELVLTVTPFLIISVLFYFTVVVQEKMLH
MUL_3557|M.ulcerans_Agy99 TFHRKKKTDTDFPRQFGYNMPLELVLTVTPFLIISVLFYFTVVVQERMLH
Mb2223c|M.bovis_AF2122/97 VFHRKKNTDTELPRQFGYNMPLELVLTVIPFLIISVLFYFTVVVQEKMLQ
Rv2200c|M.tuberculosis_H37Rv VFHRKKNTDTELPRQFGYNMPLELVLTVIPFLIISVLFYFTVVVQEKMLQ
MLBr_00875|M.leprae_Br4923 IFHRKKTTDTELPRQFGYNMPLELVLTVTPFLIISMLFYFTVIVQDKMLY
MAV_2291|M.avium_104 AFHRKKATDTELPRQFGYNMPLELVLTVTPFLIISVLFYFTVVVQEKMLH
MAB_1961|M.abscessus_ATCC_1997 AFHRHKPGDTEFPRQFGYNLPLELVLTVVPFLIIAVLFYFTVVVQNKVMH
***:* **::*******:****.*** **:**::******:**:.::
Mflv_2949|M.gilvum_PYR-GCK KEPNPEVVIDVTAFQWNWKFGYQKVEFADGTMSYDGVDNERKEAMTSAPE
Mvan_3564|M.vanbaalenii_PYR-1 KEDNPEVVIDVTAYQWNWKFGYQKVDFADGTLTYDGEDNARKEAMVSRPE
MSMEG_4268|M.smegmatis_MC2_155 KDPNPEVVIDVTAFQWNWKFGYQKIAFADGSFDYDGADPERKEAMTSRPE
TH_2397|M.thermoresistible__bu KEPDPEVVVDVTAFQWNWKFGYQSVNFKDGTFTYDGRDEERKAAVASIPE
MMAR_3244|M.marinum_M LADDPEVVVDVTAFQWNWKFGYQKVDFHDHTLTYDGADEARKRAMESKPE
MUL_3557|M.ulcerans_Agy99 LADDPEVVVDVTAFQWNWKFGYQKVDFHDHTLTYDGAVEARKRAMESKPE
Mb2223c|M.bovis_AF2122/97 IAKDPEVVIDITSFQWNWKFGYQRVNFKDGTLTYDGADPERKRAMVSKPE
Rv2200c|M.tuberculosis_H37Rv IAKDPEVVIDITSFQWNWKFGYQRVNFKDGTLTYDGADPERKRAMVSKPE
MLBr_00875|M.leprae_Br4923 LAKDPEVVIDVTAFQWNWKFGYQRVDFKDGTLTYDGVDPARKKAMVSKPE
MAV_2291|M.avium_104 IAKDPEVVVDVTAFQWNWKFGYQKVNFKDGTLTYDGADPERKKAMVSKPE
MAB_1961|M.abscessus_ATCC_1997 KDPNPEVVVDVTAFQWNWKFGYQKVAFKDGSLNYEGADPERKKAMTSKPE
:****:*:*::********* : * * :: *:* ** *: * **
Mflv_2949|M.gilvum_PYR-GCK GADEHGIEQIGAIAGKRPEDRTYLNFDKIETLGSSTEIPVLVVPSGKRIE
Mvan_3564|M.vanbaalenii_PYR-1 GVDSHGNDRVGAIYGKNPEDRSYLNFDKIETLGSSTEIPVLVVPAGKRIE
MSMEG_4268|M.smegmatis_MC2_155 GKDEHGIEKVGPIRGMTPEDRTYLNFDKIETLGTSSEIPVLVLPAGKRIE
TH_2397|M.thermoresistible__bu GVDEHGQEIRGAVHGANPQDRSYLNFNEVETVGTTSEIPVLVLPAGKRIE
MMAR_3244|M.marinum_M GKDEHGEELVGPVAGRNTEDRTYLNFDKVETLGTTSEIPVLVLPAGKRIE
MUL_3557|M.ulcerans_Agy99 GKDEHGEELVGPVAGRNTEDRTYLNFDKVETLGTTSEIPVLVLPAGKRIE
Mb2223c|M.bovis_AF2122/97 GKDKYGEELVGPVRGLNTEDRTYLNFDKVETLGTSTEIPVLVLPSGKRIE
Rv2200c|M.tuberculosis_H37Rv GKDKYGEELVGPVRGLNTEDRTYLNFDKVETLGTSTEIPVLVLPSGKRIE
MLBr_00875|M.leprae_Br4923 GKDSHGEELVGAVRGLNTEDRAYLNFDKVETLGTTTEIPVLVLPAGKRIE
MAV_2291|M.avium_104 GKDAHGEERVGAVRGLNTSDRTYLNFDKVETLGSSDEIPVLVLPTGKRIE
MAB_1961|M.abscessus_ATCC_1997 GKDAHGNELVGPVRGLNREDRTYLNFDKIETVGTSSEIPVLVVPSGKSIE
* * :* : *.: * .**:****:::**:*:: ******:*:** **
Mflv_2949|M.gilvum_PYR-GCK FQIASADVIHGFWVPEFLFKRDVLPNPKENNSDNIFQVSEIMQTGAFVGR
Mvan_3564|M.vanbaalenii_PYR-1 FEIASADVIHGFWVPEFLFKRDVMPNPEENNSDNVFQISEINQTGAFVGR
MSMEG_4268|M.smegmatis_MC2_155 FVLNSADVIHGFWVPEFLFKRDVLPEPKANNSDNVFQVSEIQQTGAFVGR
TH_2397|M.thermoresistible__bu FQIASADVIHAFWVPEFLFKRDVMPDPQANNSDHIFQISEINQTGAFVGR
MMAR_3244|M.marinum_M FQLNSADVIHAFWVPEFLFKRDVMPNPAANNSVNRFQVEQITKTGAFVGH
MUL_3557|M.ulcerans_Agy99 FQLNSADVIHAFWVPEFLFKRDVMPNPAANNSVNRFQVEQITKTGAFVGH
Mb2223c|M.bovis_AF2122/97 FQMASADVIHAFWVPEFLFKRDVMPNPVANNSVNVFQIEEITKTGAFVGH
Rv2200c|M.tuberculosis_H37Rv FQMASADVIHAFWVPEFLFKRDVMPNPVANNSVNVFQIEEITKTGAFVGH
MLBr_00875|M.leprae_Br4923 FQLNSADVVHSFWVPKFLFKRDVMPNPVANNSVNVFQVEEITKTGAFVGH
MAV_2291|M.avium_104 FDLASADVVHTFWVPEFLFKRDVIPNAEANNSIHVFQVEEINSPGAFVGH
MAB_1961|M.abscessus_ATCC_1997 FQLASADVIHSFRVVPFLFTRDVMPEPKANNSDNVFQVSKILKEGAFVGR
* : ****:* * * ***.***:*:. *** : **:.:* . *****:
Mflv_2949|M.gilvum_PYR-GCK CTEMCGTYHAMMNFELRVVEPNDFKAYLAQREAGKTNAEALRAINQEPLA
Mvan_3564|M.vanbaalenii_PYR-1 CTEMCGTYHAMMNFELRVVEPNDFKAYLDQRSAGKTNAEALLAINQPPLA
MSMEG_4268|M.smegmatis_MC2_155 CTEMCGTFHAMMNFEVRVVEPNDFKAYIDQRNAGKTNAEALAAINQPPLA
TH_2397|M.thermoresistible__bu CAEMCGTYHAMMNFEIRVVEPNDFKAYMQERIGGASNAEALLAINQEPTA
MMAR_3244|M.marinum_M CAEMCGTYHSMMNFEVRVVAANDFKAYLQQRIAGKTNAEALQAINQPPLA
MUL_3557|M.ulcerans_Agy99 CAEMCGTYHSMMNFEVRVVAANDFKAYLQQRIAGKTNAEALQAINQPPLA
Mb2223c|M.bovis_AF2122/97 CAEMCGTYHSMMNFEVRVVTPNDFKAYLQQRIDGKTNAEALRAINQPPLA
Rv2200c|M.tuberculosis_H37Rv CAEMCGTYHSMMNFEVRVVTPNDFKAYLQQRIDGKTNAEALRAINQPPLA
MLBr_00875|M.leprae_Br4923 CAEMCGTYHSMMNFEVRVVAPNDFKAYLQQRIDGKTNAEALQVIAQPPLA
MAV_2291|M.avium_104 CAEFCGTYHSMMNFEVRVVSPNDFKAYLQQRMDGKSNAEALQAIGQSPVA
MAB_1961|M.abscessus_ATCC_1997 CVEMCGTYHSMMAFELRVVSPNDFKFYLKARQDGKSNAEALASIGQSPVS
*.*:***:*:** **:*** .**** *: * * :***** * * * :
Mflv_2949|M.gilvum_PYR-GCK VTTKPFDTRRGELAPQVPAATR-
Mvan_3564|M.vanbaalenii_PYR-1 ITTKPFDTRRGELAPQMPQASR-
MSMEG_4268|M.smegmatis_MC2_155 ITTEPFESRRGELVPQASK----
TH_2397|M.thermoresistible__bu ITTSPFDSRRGEQVPPQASR---
MMAR_3244|M.marinum_M ITTHPFETRRGQQAPMPVG----
MUL_3557|M.ulcerans_Agy99 ITTHPFETRRGQQAPMPVG----
Mb2223c|M.bovis_AF2122/97 VTTHPFDTRRGELAPQPVG----
Rv2200c|M.tuberculosis_H37Rv VTTHPFDTRRGELAPQPVG----
MLBr_00875|M.leprae_Br4923 VTTHPFDTRRGQLTNSQ------
MAV_2291|M.avium_104 VTTHPFDSKRGQLAGSQ------
MAB_1961|M.abscessus_ATCC_1997 ITTRPFDGRRGDLAPVDNNAAKN
:** **: :**: .