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VTQQSALHLVLGDEELLVERAVAAVLKSARKSAGTADVPVDRLRAGEVSVSELAELLSPSLFADERVVVL ESAAEAGKEAVALIQSAAADLPAGTLLVIVHSGGGRAKALADHVKKLGAEVHPCARIAKASERADFVRKE FRSLRVKVDDDTVTAVLDAVGSDIRELAAACSQLVADTGGSVDAAAVRRYHSGRAEVKGFDIADKAVLGD VAGAAEALRWAMMAGEPHVVLADALAEAVHTIARVGPLSGDPYRLAGELGMPPWRVQKAQKQARRWSRDS VAEAVRVVAALNADVKGAAADADYALEKAVRSVANLVSD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2664 | - | - | 100% (319) | hypothetical protein Mflv_2664 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2436c | - | 1e-143 | 81.47% (313) | hypothetical protein Mb2436c |
| M. tuberculosis H37Rv | Rv2413c | - | 1e-143 | 81.47% (313) | hypothetical protein Rv2413c |
| M. leprae Br4923 | MLBr_00603 | - | 1e-138 | 79.68% (315) | hypothetical protein MLBr_00603 |
| M. abscessus ATCC 19977 | MAB_1633 | - | 1e-131 | 76.04% (313) | hypothetical protein MAB_1633 |
| M. marinum M | MMAR_3734 | holA | 1e-142 | 79.26% (323) | DNA polymerase III, delta subunit HolA |
| M. avium 104 | MAV_1769 | - | 1e-139 | 79.31% (319) | hypothetical protein MAV_1769 |
| M. smegmatis MC2 155 | MSMEG_4572 | - | 1e-148 | 85.26% (312) | hypothetical protein MSMEG_4572 |
| M. thermoresistible (build 8) | TH_1459 | - | 1e-146 | 81.70% (317) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3677 | holA | 1e-140 | 78.33% (323) | hypothetical protein MUL_3677 |
| M. vanbaalenii PYR-1 | Mvan_3913 | - | 1e-159 | 91.43% (315) | hypothetical protein Mvan_3913 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2436c|M.bovis_AF2122/97 --------------------------------------------------
Rv2413c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1769|M.avium_104 -------------------------------------------------M
MLBr_00603|M.leprae_Br4923 MLVLWRCFRVAMISALMVAVACLPDWLSGFLTGGLIAGSSARRATIYGVS
MMAR_3734|M.marinum_M -------------------------------------------------M
MUL_3677|M.ulcerans_Agy99 -------------------------------------------------M
Mflv_2664|M.gilvum_PYR-GCK -------------------------------------------------M
Mvan_3913|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4572|M.smegmatis_MC2_155 ----------------------------------------------MGVT
TH_1459|M.thermoresistible__bu -------------------------------VDGGRARTVGVTWHDRGVS
MAB_1633|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2436c|M.bovis_AF2122/97 -----MHLVLGDEELLVERAVADVLRSARQRAGT----ADVPVSRMRAGD
Rv2413c|M.tuberculosis_H37Rv -----MHLVLGDEELLVERAVADVLRSARQRAGT----ADVPVSRMRAGD
MAV_1769|M.avium_104 SEVSPLHLVLGDEELLVERAVAEVLAEARKRAGASG-DADVPVNRMRAGD
MLBr_00603|M.leprae_Br4923 NKFSSLHLVLGNEELLVERAVGEVLRSARQRAGT----QDVPVSRMRAGD
MMAR_3734|M.marinum_M SEISPLHLVLGDEELLVERAVGDIVRAARERARQAAGTDDVPVNRMRAGD
MUL_3677|M.ulcerans_Agy99 SEISPLHLVLGDEELLVERAVGDIVRAARERARQAAGTDDVPVNRMRAGD
Mflv_2664|M.gilvum_PYR-GCK TQQSALHLVLGDEELLVERAVAAVLKSARKSAGT----ADVPVDRLRAGE
Mvan_3913|M.vanbaalenii_PYR-1 --MTGLHLVLGDEELLVERAVAEVLRTARASAGT----SDVPVDRLRAGE
MSMEG_4572|M.smegmatis_MC2_155 DG---LHLVLGDEELLVERAVGAILRDIRKRAGS----DDVPVDRLRAGE
TH_1459|M.thermoresistible__bu DQDGRLHLVLGDEEFLVERAVAAVLRDARRRAGS----ADIPVNRMRAGD
MAB_1633|M.abscessus_ATCC_1997 -MTDALHLILGDEELLVERAVTSVLHAVRGKAGA-----DIPVNRLRAGQ
:**:**:**:****** :: * * *:**.*:***:
Mb2436c|M.bovis_AF2122/97 VGAYELAELLSPSLFAEERIVVLGAAAEAGKDAAAVIESAAADLPAGTVL
Rv2413c|M.tuberculosis_H37Rv VGAYELAELLSPSLFAEERIVVLGAAAEAGKDAAAVIESAAADLPAGTVL
MAV_1769|M.avium_104 VSTYELAELLSPSLFADERIVVLEAAGEAGKDAAAVILSAAAEMPAGVVL
MLBr_00603|M.leprae_Br4923 VGTYELTELLSPSLFADERIVVLEAAAEAGKEAAALIVSAAADIPQGTVL
MMAR_3734|M.marinum_M VSTYELAELLSPSLFAEERIVVLEAAAEAGKDAVALIASTAADIPPGTVL
MUL_3677|M.ulcerans_Agy99 VSTYELAELLSPSLFAEERIVVLEAAAEAGKDAVALIASTAADIPPGTVL
Mflv_2664|M.gilvum_PYR-GCK VSVSELAELLSPSLFADERVVVLESAAEAGKEAVALIQSAAADLPAGTLL
Mvan_3913|M.vanbaalenii_PYR-1 VSVSELAELLSPSLFADERVVVLESAAEAGKDAVALIQTAAADLPDGTLL
MSMEG_4572|M.smegmatis_MC2_155 VSTSELAELLSPSLFAEERLVVLEAAAEAGKDAVALIASAAADLPPGTVL
TH_1459|M.thermoresistible__bu VSTHELAELLSPSLFADERVVVLEPAAEAGKDAVALISDAAADLPAGIVL
MAB_1633|M.abscessus_ATCC_1997 VDVAELAELLSPSLFADERVIVIEAAAEAGKDAVTLIEQAATDLPPGTFL
*.. **:*********:**::*: .*.****:*.::* :*:::* * .*
Mb2436c|M.bovis_AF2122/97 VVVHSGGGRAKSLANQLRSMGAQVHPCARITKVSERADFIRSEFASLRVK
Rv2413c|M.tuberculosis_H37Rv VVVHSGGGRAKSLANQLRSMGAQVHPCARITKVSERADFIRSEFASLRVK
MAV_1769|M.avium_104 VVVHSGGGRAKALATELQSLGAVVHPCARITKLSERIDFVRKEFRRLRVK
MLBr_00603|M.leprae_Br4923 VVVHSGGGRAKALANELQSLGATVHPCARITKLSERTDFVRKELRSLRVK
MMAR_3734|M.marinum_M VVVHSGGGRAKALAGELKSLGAQVHPCARISKASERVDFVRGEFRALRVK
MUL_3677|M.ulcerans_Agy99 VVVHSGGGRTKALAGELKSLGAQVHPCARISKASERVDFVRGEFRALRVK
Mflv_2664|M.gilvum_PYR-GCK VIVHSGGGRAKALADHVKKLGAEVHPCARIAKASERADFVRKEFRSLRVK
Mvan_3913|M.vanbaalenii_PYR-1 VVVHSGGGRAKALADQLKKLGAEVHPCARITKASERADFVRKEFRTLRVK
MSMEG_4572|M.smegmatis_MC2_155 VVIHSGGGRAKALADQLKKLGAEVHPCARITKPAERADFVRSEFRRLRAK
TH_1459|M.thermoresistible__bu VVVHSGGGRAKALAEKLKKLGAQVYPCARITKQADRAEFVRREFRAGKVK
MAB_1633|M.abscessus_ATCC_1997 LVQHSGGGRAKALATTLQNLGASVHNCARITKAAERADFVHKEFRRLGQK
:: ******:*:** ::.:** *: ****:* ::* :*:: *: *
Mb2436c|M.bovis_AF2122/97 VDDETVTALLDAVGSDVRELASACSQLVADTGGAVDAAAVRRYHSGKAEV
Rv2413c|M.tuberculosis_H37Rv VDDETVTALLDAVGSDVRELASACSQLVADTGGAVDAAAVRRYHSGKAEV
MAV_1769|M.avium_104 ADEETVTAMLDAVGSDLRELASACSQLVADTGGAVDAAAVRRYHSGKAEV
MLBr_00603|M.leprae_Br4923 VDEGAVTALLNAVGSDVRELASACSQLVADTAGDVDADAVQRYHSGKAEV
MMAR_3734|M.marinum_M VGEDTVTALLDAVGSDIRELASACSQLVADTGGDVDAVAVRRYHSGKAEV
MUL_3677|M.ulcerans_Agy99 VGEDTVTALLDAVGSDIRELASACSQLVADTGGDVDAVAVRRYHSGKAEV
Mflv_2664|M.gilvum_PYR-GCK VDDDTVTAVLDAVGSDIRELAAACSQLVADTGGSVDAAAVRRYHSGRAEV
Mvan_3913|M.vanbaalenii_PYR-1 VDEATVTAVLDALGSDIRELAAACSQLVADTGGAVDAAAVRRYYSGRAEV
MSMEG_4572|M.smegmatis_MC2_155 VSEDTVSAVLDAVGSNIRELAAVCSQLVADTAGEVDAAAVRRYHSGKAEV
TH_1459|M.thermoresistible__bu VSDDTVAAVLDAVGSDIRELAAVCSQLIADTGGQVDAAAVRRYYSGKAEV
MAB_1633|M.abscessus_ATCC_1997 VDADVVAIVIDAVGSDIRELAAACSQLVSDTDGSVDGAAVRRYHSGRAEV
.. .*: :::*:**::****:.****::** * **. **:**:**:***
Mb2436c|M.bovis_AF2122/97 RGFDIADKAVAGDVAGAAEALRWAMMRGEPLVVLADALAEAVHTIGRVGP
Rv2413c|M.tuberculosis_H37Rv RGFDIADKAVAGDVAGAAEALRWAMMRGEPLVVLADALAEAVHTIGRVGP
MAV_1769|M.avium_104 KGFDIADKAVAGDIEGAAEALRWAMMRGEPLVVLADALAEAIHTIGRVGP
MLBr_00603|M.leprae_Br4923 KGFDIADKAVGGDVSGAVEALRWAMMRGEPLVVLADALAEAVHTIGRVGP
MMAR_3734|M.marinum_M KGFDIADKAVAGDVAGATEALRWAMMRGEPLVVLADALAEAIHTIGRVGP
MUL_3677|M.ulcerans_Agy99 KGFDIADKAVAGDVAGATEALRWAMMRGEPLLVLADALAEAIHTIGRVGP
Mflv_2664|M.gilvum_PYR-GCK KGFDIADKAVLGDVAGAAEALRWAMMAGEPHVVLADALAEAVHTIARVGP
Mvan_3913|M.vanbaalenii_PYR-1 KGFDIADKAVVGDVAGAAEALRWAMMAGEPHVVLADALAEAVHTIARVGP
MSMEG_4572|M.smegmatis_MC2_155 KGFDIADKAVVGDVAGAAEALRWAMLAGEPHVVLADALAEAVHTIARVGP
TH_1459|M.thermoresistible__bu KGYDIADKAVVGDVAGAAEALRWALMRGEPHVVLADALAEAVHSIARVGP
MAB_1633|M.abscessus_ATCC_1997 SGFDIADKAVTGDIAGSTETLRWAMQRGVPHVLLADALAEAVHTIARVGP
*:******* **: *:.*:****: * * ::********:*:*.****
Mb2436c|M.bovis_AF2122/97 QSGDPYRLAAQLGMPPWRVQKAQKQARRWSRDTVATAMRLVAELNANVKG
Rv2413c|M.tuberculosis_H37Rv QSGDPYRLAAQLGMPPWRVQKAQKQARRWSRDTVATAMRLVAELNANVKG
MAV_1769|M.avium_104 LSGDPYRLAAQLGMPPWRVQKAQKQARYWSRDSVATAMKVVATLNANVKG
MLBr_00603|M.leprae_Br4923 LSGDSYRLASRLGMPPWRVQKAQQQARRWSRDTVAAAMRVVAALNADVKG
MMAR_3734|M.marinum_M LSGDPYRMASQLGMPPWRVQKAQKQARRWSRDKVATAMQLVAQLNADVKG
MUL_3677|M.ulcerans_Agy99 LSGDPYRMASQLGMRPWRVQKAQKQARRWSRDKVATAMQLVAQLNADVKG
Mflv_2664|M.gilvum_PYR-GCK LSGDPYRLAGELGMPPWRVQKAQKQARRWSRDSVAEAVRVVAALNADVKG
Mvan_3913|M.vanbaalenii_PYR-1 LSGDPYRLAGELGMPPWRVQKAQKQARRWSRDSVAQALRLVAALNADVKG
MSMEG_4572|M.smegmatis_MC2_155 LSGDPYRLAGELGMPPWRVQKAQKQSRRWSRESVAEAMKVVAALNADVKG
TH_1459|M.thermoresistible__bu VSGDPYRLAGELGMPPWRVQKAQKQARRWSRESVAEAIRLVAALNADVKG
MAB_1633|M.abscessus_ATCC_1997 IKQNAYAAASELGMPPWRIEKAQKQARRWTRDAVAEAMRVVAALNADVKG
. :.* *..*** ***::***:*:* *:*: ** *:::** ***:***
Mb2436c|M.bovis_AF2122/97 AVADADYALESAVRQVAELVADRGR
Rv2413c|M.tuberculosis_H37Rv AVADADYALESAVRQVAELVADRGR
MAV_1769|M.avium_104 AVADADYALESAVRRVAELAGGRNR
MLBr_00603|M.leprae_Br4923 AAADAYYALESAVRKVAELAADGSR
MMAR_3734|M.marinum_M AAADADYALESAVRTVAELVADRA-
MUL_3677|M.ulcerans_Agy99 AAADADYALESAVRTVAELVADRA-
Mflv_2664|M.gilvum_PYR-GCK AAADADYALEKAVRSVANLVSD---
Mvan_3913|M.vanbaalenii_PYR-1 AAADADYALEKAVRSVAELASE---
MSMEG_4572|M.smegmatis_MC2_155 VAADADYALEAAVRRVAQLAAG---
TH_1459|M.thermoresistible__bu AAADAEYALESTVRKVAELVAD---
MAB_1633|M.abscessus_ATCC_1997 VAADADYALESAVRRVAELVST---
..*** **** :** **:*..