For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. gilvum PYR-GCK Mflv_2612 (-)

annotation: xylose isomerase domain-containing protein
coordinates: 2732482 - 2733366
length: 294

KIAGAPISWGVCEVPGWGHQLSADRVLTEMRQAGLTATELGPEGFLPADPAELVKLLDGYGLACVGGFVP
VVLFSDDHDPADGLAGPLESLVAAGAEVVVLAAATGQDGYDRRPVLDEKQWATLLSNLDRLADLVSARGL
TAVLHPHVGTMVETRAEVDRVLAGSRIPLCLDTGHLLIGGTDPLALTHEVPERIRHAHLKDVDAGLAAKV
QSGELTYTQAVAAGMYVPLGAGDVDIAGIITALEDNGFDGWYVMEQDKILHANPGATPDGRGPLGDVLAS
VAFLESAATGVSS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2612--100% (294)xylose isomerase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0087-3e-0529.05% (210) hypothetical protein MMAR_0087
M. avium 104-----
M. smegmatis MC2 155MSMEG_4651-1e-11671.58% (285) AP endonuclease, family protein 2
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_3969-1e-14083.67% (294) xylose isomerase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2612|M.gilvum_PYR-GCK          ---MKIAGAPISWG-----VCEVPGWGHQLSADRVLTEMRQAGLTATELG
Mvan_3969|M.vanbaalenii_PYR-1       ---MKIAGAPISWG-----VCEVPGWGYQLDSDRVLAEMRQAGLTATELG
MSMEG_4651|M.smegmatis_MC2_155      MTDLKIAGAPISWG-----VCEVPGWGHQLDRQRVLSEMRTAGLTATELG
MMAR_0087|M.marinum_M               MRLTNVAHLRLPFGRLWGYDVSVSDLGRQLPVSFDQRIHVAAGARPGSWM
                                        ::*   :.:*       .*.. * **  .        **  . .  

Mflv_2612|M.gilvum_PYR-GCK          PEGFLPADPAELVKLLDGYG--LACVGGFVPVVLFSDDHDP---------
Mvan_3969|M.vanbaalenii_PYR-1       PEGFLPTDTGELVKLLDGFG--LACVGGFVPVVLYKDDHDP---------
MSMEG_4651|M.smegmatis_MC2_155      PDGFLPSDTGELTALLGAHD--LSCVGGFVPVVLHDAEHDP---------
MMAR_0087|M.marinum_M               ALSIRLPAGVSRQSLADAWLGVIARHGTLRTAFTLGADGDPQLHEIDVQP
                                    . .:  .   .   * ..    ::  * : ...    : **         

Mflv_2612|M.gilvum_PYR-GCK          ----------ADGLAGPLESLVAAGAE--------VVVLAAATGQDGYDR
Mvan_3969|M.vanbaalenii_PYR-1       ----------ADDLAGPLESLVAAGAG--------IVVLAAATGLDGYDE
MSMEG_4651|M.smegmatis_MC2_155      ----------ADDLAGPLASLRAANAG--------VVVLAAATGADGYDS
MMAR_0087|M.marinum_M               GKWVEHEIAAGQEVNDALRVVLNAACSPDQRPSHRLCVLETAAGLTVVIA
                                              .: : ..*  :  * .         : ** :*:*      

Mflv_2612|M.gilvum_PYR-GCK          RPVLDEKQWATLLSNLDRLADLVSAR-GLTAVLHPHVGTMVETRAEVDR-
Mvan_3969|M.vanbaalenii_PYR-1       RPDLDENHWATLLSNLDRLAGIVAAR-GLTAVLHPHVGTMVETRAEVDR-
MSMEG_4651|M.smegmatis_MC2_155      RPTLSERQWATLLSNLDRLARIADEA-GLLAVLHPHVGTMVETREDVDR-
MMAR_0087|M.marinum_M               ADHAHVDMWSMLVIARDLLSMLADARTGRTSSLQPRPAFVVHTQALLDRP
                                            *: *:   * *: :.    *  : *:*: . :*.*:  :** 

Mflv_2612|M.gilvum_PYR-GCK          ----VLAGSRIPLCLDTGHLLIGGTDPLALTHEVPERIRHAHLKDVDAGL
Mvan_3969|M.vanbaalenii_PYR-1       ----VLSGSHIPLCLDTGHLLIGGTDPLALTREVPGRIKHAHLKDVDAAL
MSMEG_4651|M.smegmatis_MC2_155      ----VLNGSQIPLCLDTGHLLIGGTDPLELAKAVPHRIKHAHLKDVNAAL
MMAR_0087|M.marinum_M               PAPDRVRARWAQIINDSGGVMPRFPLPLGKSGPHPERVEVRDVFDVDDGA
                                         : .    :  *:* ::   . **  :   * *:.  .: **: . 

Mflv_2612|M.gilvum_PYR-GCK          AAKVQS---GELTYTQAVAAGMYVP---LGAGDVDIAGIITALEDNGFD-
Mvan_3969|M.vanbaalenii_PYR-1       AAKVQS---GELSYTQAVAAGMYVP---LGSGDVDIAGIVKTLEDNGFD-
MSMEG_4651|M.smegmatis_MC2_155      AARVRA---GEVSYTDAVRAGIYTP---LGTGDIDISGIVSVLRDNGFD-
MMAR_0087|M.marinum_M               AFAAQARNDGVSTLALAVVAMTAVTRELAGAPLRAVFPVHSRFEEKWHDS
                                    *  .::   *  : : ** *   ..    *:    :  : . :.:: .* 

Mflv_2612|M.gilvum_PYR-GCK          -GWYVME---------QDKILHANPGATPDGRGPLGDVLA----------
Mvan_3969|M.vanbaalenii_PYR-1       -GWYVME---------QDTILDGEP----RGAGPLADVVA----------
MSMEG_4651|M.smegmatis_MC2_155      -GWFVME---------QDTILDAEP----TDEGPLRDVRT----------
MMAR_0087|M.marinum_M               VGWFITNSVLESAVVEPNAAAAAVKEAVQLGSWPLADVLAPWGGMPMAPG
                                     **:: :          :    .       .  ** ** :          

Mflv_2612|M.gilvum_PYR-GCK          --SVAFLESAATGVSS----------------------------------
Mvan_3969|M.vanbaalenii_PYR-1       --SVAFLQGAASGVSA----------------------------------
MSMEG_4651|M.smegmatis_MC2_155      --SVAYLGTLTA--------------------------------------
MMAR_0087|M.marinum_M               MFAISWLDQLRLPVRIDSVGLDAQYVSARIHTDGVMLWFIQDESGLHLRC
                                      ::::*                                           

Mflv_2612|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3969|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4651|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0087|M.marinum_M               RYPDTAEARTNVGSWLDLLVARLQALAQSSVRGLLRVAGRTFRVQRATRE
                                                                                      

Mflv_2612|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3969|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4651|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0087|M.marinum_M               HVGVIAELLSDDEFGQDREGAELERYEAAYDILVRNRSNYLGVVLNGSDM
                                                                                      

Mflv_2612|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3969|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4651|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0087|M.marinum_M               VVATVQLTIIPGLSRGGATRLQIEGLRVAKAERAQGLGTALVEWAHNYGR
                                                                                      

Mflv_2612|M.gilvum_PYR-GCK          --------------------------------------
Mvan_3969|M.vanbaalenii_PYR-1       --------------------------------------
MSMEG_4651|M.smegmatis_MC2_155      --------------------------------------
MMAR_0087|M.marinum_M               AHGAQLAQVTTDEARERARAFYRRLGYHAAHVGLKRTI