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MNPDAMRPIGIFDSGVGGLTVARAVIDQLPHEDIIYVGDTGNGPYGPLTIPQIRAHALAIGDDLAGRGIK ALVIACNSASSACLRDARERYAPIPVVEVILPAVRRAVAATRNGRIGVIGTAATIASGAYQDSFAAARDI EVFGVACPRFVDFVERGVTSGRQVLGLAEAYLEPLQRAQVDTLVLGCTHYPMLSGLIQLAMGDHVTLVSS AEETAKDLLRVLTERELLKPHTGDPAAPARRVFEATGDPEAFTALAARFLGPSLDGVRPVTRHARLRT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2356 | - | - | 100% (278) | glutamate racemase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1373 | murI | 1e-124 | 83.40% (265) | glutamate racemase |
| M. tuberculosis H37Rv | Rv1338 | murI | 1e-124 | 83.40% (265) | glutamate racemase |
| M. leprae Br4923 | MLBr_01172 | murI | 1e-121 | 80.00% (270) | glutamate racemase |
| M. abscessus ATCC 19977 | MAB_1482 | - | 1e-121 | 81.30% (262) | glutamate racemase |
| M. marinum M | MMAR_4058 | murI | 1e-123 | 82.64% (265) | glutamate racemase MurI |
| M. avium 104 | MAV_1555 | murI | 1e-125 | 82.78% (273) | glutamate racemase |
| M. smegmatis MC2 155 | MSMEG_4903 | murI | 1e-135 | 87.82% (271) | glutamate racemase |
| M. thermoresistible (build 8) | TH_1017 | - | 1e-134 | 86.45% (273) | PROBABLE GLUTAMATE RACEMASE MURI |
| M. ulcerans Agy99 | MUL_3925 | murI | 1e-123 | 82.64% (265) | glutamate racemase |
| M. vanbaalenii PYR-1 | Mvan_4289 | - | 1e-142 | 92.99% (271) | glutamate racemase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4058|M.marinum_M MSSP----LAPVGIFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGP
MUL_3925|M.ulcerans_Agy99 MSSP----LAPVGIFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGP
Mb1373|M.bovis_AF2122/97 MNSP----LAPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGP
Rv1338|M.tuberculosis_H37Rv MNSP----LAPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGP
MLBr_01172|M.leprae_Br4923 MSSP----LLPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGP
MAV_1555|M.avium_104 MSSA----LAPVGIFDSGVGGLTVARAIIDQLPDEHIIYVGDTGHGPYGP
MAB_1482|M.abscessus_ATCC_1997 MSD------APIGIFDSGVGGLTVARAIIDQLPDEDILYVGDTGNGPYGP
Mflv_2356|M.gilvum_PYR-GCK MN-PDAMR--PIGIFDSGVGGLTVARAVIDQLPHEDIIYVGDTGNGPYGP
Mvan_4289|M.vanbaalenii_PYR-1 MSGPTEPTGMPIGIFDSGVGGLTVARAVIDQLPDEDIIYIGDTGNGPYGP
MSMEG_4903|M.smegmatis_MC2_155 MS----DRLAPIGIFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGP
TH_1017|M.thermoresistible__bu MS---GDAFAPVGIFDSGVGGLTVARAIIDQLPDESIIYIGDTGNGPYGP
*. *:*:*************:*****.* *:*:****:*****
MMAR_4058|M.marinum_M LTIPEVRAHALAIGDDLVGRGVKALVIACNTASAACLRDARERYD-VPVV
MUL_3925|M.ulcerans_Agy99 LTIPEVRAHALAIGDDLVGRGVKALVIACNTASAACLRDARERYD-VPVV
Mb1373|M.bovis_AF2122/97 LTIPEIRAHALAIGDDLVGRGVKALVIACNSASSACLRDARERYQ-VPVV
Rv1338|M.tuberculosis_H37Rv LTIPEIRAHALAIGDDLVGRGVKALVIACNSASSACLRDARERYQ-VPVV
MLBr_01172|M.leprae_Br4923 LSIPEIRAHALAICDDLVGRGVKILVIACNTASAACLRDARERYD-VPVV
MAV_1555|M.avium_104 LSIPEVRAHALAIGDDLVGRGVKALVIACNTASAACLRDARERYE-VPVV
MAB_1482|M.abscessus_ATCC_1997 LTIPEIRTHALTIGDDLVGRGVKALVIACNTASAACLRDARERYAPVPVI
Mflv_2356|M.gilvum_PYR-GCK LTIPQIRAHALAIGDDLAGRGIKALVIACNSASSACLRDARERYAPIPVV
Mvan_4289|M.vanbaalenii_PYR-1 LTIPEIRAHALAIGDDLAGRGIKALVIACNSASSACLRDARERYAPIPVV
MSMEG_4903|M.smegmatis_MC2_155 LTIPQIRAHSLAIGDDLVSRGVKALVIACNTASSACLRDARERYSPVPVV
TH_1017|M.thermoresistible__bu LTLPEIRAHALAIGDDLVERGVKALVIACNSASAACLRDARERYAPVPVV
*::*::*:*:*:* ***. **:* ******:**:********** :**:
MMAR_4058|M.marinum_M EVILPAVRRAVATTRNGRIGVIGTRATITSHAYQDAFAAARDTEITAVAC
MUL_3925|M.ulcerans_Agy99 EVILPAVRRAVATTRNGRIGVIGTRATITSHAYQDAFAAARDTEITAVAC
Mb1373|M.bovis_AF2122/97 EVILPAVRRAVAATRNGRIGVIGTRATITSHAYQDAFAAARDTEITAVAC
Rv1338|M.tuberculosis_H37Rv EVILPAVRRAVAATRNGRIGVIGTRATITSHAYQDAFAAARDTEITAVAC
MLBr_01172|M.leprae_Br4923 EVILPAVRRAVAATRNGRIGVIGTRATIASHAYQDAFAAARDTEITAVAC
MAV_1555|M.avium_104 EVILPAVRRAVATTRNGRIGVIGTQATINSHAYQDAFAAARDTEITAVAC
MAB_1482|M.abscessus_ATCC_1997 EVVLPAVRRAVHTTHNNKIGVIGTEATIASGAYQDAFAAARDTEITAVAC
Mflv_2356|M.gilvum_PYR-GCK EVILPAVRRAVAATRNGRIGVIGTAATIASGAYQDSFAAARDIEVFGVAC
Mvan_4289|M.vanbaalenii_PYR-1 EVILPAVRRAVATTRNGRIGVIGTAATIASGAYQDTFAAARDIEVFGVAC
MSMEG_4903|M.smegmatis_MC2_155 EVILPAVRRAVAATRNGRIGVIGTQATIASGAYQDAFAAARDTEVFTVAC
TH_1017|M.thermoresistible__bu EVILPAVRRAVATTRNGRIGVIGTAATIASGAYQDAFAAARDTEIFGVAC
**:******** :*:*.:****** *** * ****:****** *: ***
MMAR_4058|M.marinum_M PRFVDFVERGVTSGRQVLGLAEGYLEPLQRSGVDTLVLGCTHYPLLSGLI
MUL_3925|M.ulcerans_Agy99 PRFVDFVERGVTSGRQVLGLAEGYLEPLQRSGVDTLVLGCTHYPLLSGLI
Mb1373|M.bovis_AF2122/97 PRFVDFVERGVTSGRQVLGLAQGYLEPLQRAEVDTLVLGCTHYPLLSGLI
Rv1338|M.tuberculosis_H37Rv PRFVDFVERGVTSGRQVLGLAQGYLEPLQRAEVDTLVLGCTHYPLLSGLI
MLBr_01172|M.leprae_Br4923 PRFVDFVECGVTSGRQVLGLAEGYLEPLQRSGVDTLVLGCTHYPLLAGLI
MAV_1555|M.avium_104 PRFVDFVERGVTSGRQVLGLAEGYLEPLQRAQVDTLVLGCTHYPLLSGLI
MAB_1482|M.abscessus_ATCC_1997 PRFVDFVERGITSGRQVLQLAEGYLEPLQRAQVDTVVLGCTHYPLLSGLI
Mflv_2356|M.gilvum_PYR-GCK PRFVDFVERGVTSGRQVLGLAEAYLEPLQRAQVDTLVLGCTHYPMLSGLI
Mvan_4289|M.vanbaalenii_PYR-1 PRFVDFVERGVTSGRQVLGLAEGYLEPLQRAEVDTLVLGCTHYPMLSGLI
MSMEG_4903|M.smegmatis_MC2_155 PRFVDFVERGVTSGRQVLGLAEGYLEPLQLAEVDTLVLGCTHYPMLSGLI
TH_1017|M.thermoresistible__bu PRFVDFVERGITSGRQVLGLAEGYLEPLQRAGVDTLVLGCTHYPMLSGLI
******** *:******* **:.****** : ***:********:*:***
MMAR_4058|M.marinum_M QLVMGDNVTLVSSAEETAKEVLRVLTERDILRPHDAPP----ATRLFEAT
MUL_3925|M.ulcerans_Agy99 QLVMGDNVTLVSSAEETAKEVLRVLTERDILRPHDAPP----ATRLFEAT
Mb1373|M.bovis_AF2122/97 QLAMGENVTLVSSAEETAKEVVRVLTEIDLLRPHDAPP----ATRIFEAT
Rv1338|M.tuberculosis_H37Rv QLAMGENVTLVSSAEETAKEVVRVLTEIDLLRPHDAPP----ATRIFEAT
MLBr_01172|M.leprae_Br4923 QLAMGENVTLVSSAEETAKEVLRVLTERDLLRRHDAPP----VNRVFEAT
MAV_1555|M.avium_104 QLAMGDNVTLVSSAEETAKEVLRVLTERDLLHPHPDDPRAAGPSRVFEAT
MAB_1482|M.abscessus_ATCC_1997 QLAMGEDVTLVSSAEETAKDLLRVLSEKDLLRPHPERPGTASPNRVFEAT
Mflv_2356|M.gilvum_PYR-GCK QLAMGDHVTLVSSAEETAKDLLRVLTERELLKPHTGDPA-APARRVFEAT
Mvan_4289|M.vanbaalenii_PYR-1 QLVMGDHVTLVSSAEETAKDLLRVLTKRELLKPHPGDPA-VRAHRQFEAT
MSMEG_4903|M.smegmatis_MC2_155 QLAMGDNVTLVSSAEETAKDLLRVLTELDLLRPHPDDPS-VTAVRRFEAT
TH_1017|M.thermoresistible__bu QLAMGDHVTLVSSAEETAKELLRVLTERDLLRPHDAGP----PRRVFEAT
**.**:.************:::***:: ::*: * * * ****
MMAR_4058|M.marinum_M GDPEAFMALAARFLGPALTGVQP----VRP-SGMH---
MUL_3925|M.ulcerans_Agy99 GDPEAFMALAARFLGPALTGVQP----VRP-SGMH---
Mb1373|M.bovis_AF2122/97 GDPEAFTKLAARFLGPVLGGVQP----VHP-SRIH---
Rv1338|M.tuberculosis_H37Rv GDPEAFTKLAARFLGPVLGGVQP----VHP-SRIH---
MLBr_01172|M.leprae_Br4923 GDPEAFIQLAARFLGPAVSGVQP----ARLHSRVR---
MAV_1555|M.avium_104 GDPEAFTRLAARFLGPAVSGVRP----VHH-VRID---
MAB_1482|M.abscessus_ATCC_1997 GDPEAFRALAARFLGPAVTAVQTRASSVPGYTEITRSS
Mflv_2356|M.gilvum_PYR-GCK GDPEAFTALAARFLGPSLDGVRP----VTRHARLRT--
Mvan_4289|M.vanbaalenii_PYR-1 GDPEAFTALAARFLGPTLDGVRP----VQRHVGTRT--
MSMEG_4903|M.smegmatis_MC2_155 GDPEAFTALAARFLGPTLDGVRP----VRRHAGAGR--
TH_1017|M.thermoresistible__bu GDPEGFTTLAARFLGPTLDGVRP----VAHHVPGRR--
****.* ******** : .*:. .