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VRKWKRVEGPSGPRFRSALAAHEVELLSSLVTSLLGMLDDREASAPRDELAEITGMRTGNSVAPQDDTMK RLLPDFYRPATEHPAGSSAAESLNSALRSLHEPEILDAKREAAQRLLDTLPAAGGKFELSEQDAHAWASA VNDVRLALGTMLDIGADGPDRLPGDHPMSGHLDVYQWLTVLQEYLVVSLMGGSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2350 | - | - | 100% (194) | hypothetical protein Mflv_2350 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1367 | - | 1e-68 | 62.37% (194) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv1332 | - | 1e-68 | 62.37% (194) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01166 | - | 1e-65 | 61.66% (193) | hypothetical protein MLBr_01166 |
| M. abscessus ATCC 19977 | MAB_1476 | - | 2e-66 | 62.69% (193) | hypothetical protein MAB_1476 |
| M. marinum M | MMAR_4066 | - | 2e-70 | 62.69% (193) | hypothetical protein MMAR_4066 |
| M. avium 104 | MAV_1552 | - | 2e-73 | 67.02% (191) | hypothetical protein MAV_1552 |
| M. smegmatis MC2 155 | MSMEG_4909 | - | 4e-84 | 76.44% (191) | hypothetical protein MSMEG_4909 |
| M. thermoresistible (build 8) | TH_1209 | - | 7e-72 | 65.64% (195) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3930 | - | 1e-70 | 62.69% (193) | hypothetical protein MUL_3930 |
| M. vanbaalenii PYR-1 | Mvan_4295 | - | 1e-98 | 89.69% (194) | hypothetical protein Mvan_4295 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2350|M.gilvum_PYR-GCK ----------------------MRKWKRVEGPSGPRFRSALAAHEVELLS
Mvan_4295|M.vanbaalenii_PYR-1 ----------------------MRKWKRVEGAGGPRFRSALAAHEAELLS
MSMEG_4909|M.smegmatis_MC2_155 ----------------------MRKWKRVEAADGPRFRSALEGHEAALLS
Mb1367|M.bovis_AF2122/97 MPPVCGRRCSRTGEIRGYSGSIVRRWKRVETRDGPRFRSSLAPHEAALLK
Rv1332|M.tuberculosis_H37Rv MPPVCGRRCSRTGEIRGYSGSIVRRWKRVETRDGPRFRSSLAPHEAALLK
MMAR_4066|M.marinum_M ----------------------MRKWKRVETRNGPRFRSSLAPHEATLLK
MUL_3930|M.ulcerans_Agy99 ----------------------MRKWKRVETRNGPRFRSSLAPHEATLLK
MAV_1552|M.avium_104 ----------------------MRKWKRVETADGPRFRSALASHEAALLK
MLBr_01166|M.leprae_Br4923 ----------------------MRKWKRVETANGPRFRSVVAPHEVALLK
TH_1209|M.thermoresistible__bu ----------------------VRLWKRVQTASGPRFRSALESHEATLLR
MAB_1476|M.abscessus_ATCC_1997 ----------------------MRKWKRVNASDGIRLRSEMEPHEAALVQ
:* ****: .* *:** : **. *:
Mflv_2350|M.gilvum_PYR-GCK SLVTSLLGMLDDREASAPRDELAEITGMRTGNSVAPQDDTMKRLLPDFYR
Mvan_4295|M.vanbaalenii_PYR-1 SLVTSLLGMLDDREASAPVDELAEITGMRTGNSVPPQDDTLKRLLPDFYR
MSMEG_4909|M.smegmatis_MC2_155 SLVGSMLGMLDERESSAPADELEAITGIKTGHSRPPEDATMKRLLPDFFR
Mb1367|M.bovis_AF2122/97 NLAGAMIGLLDDRDSSSPSDELEEITGIKTGHAQRPGDPTLRRLLPDFYR
Rv1332|M.tuberculosis_H37Rv NLAGAMIGLLDDRDSSSPSDELEEITGIKTGHAQRPGDPTLRRLLPDFYR
MMAR_4066|M.marinum_M NLVGAMIGLLDERESTAPSDELEEITGIRTGHAQRPGDPTLRRLLPDFYK
MUL_3930|M.ulcerans_Agy99 NLVGAMIGLLDERESTAPSDELEEITGIRTGHAQRPGDPTLRRLLPDFYK
MAV_1552|M.avium_104 NLATAMIGLLDERESSSPADELEEITGIKTGNAQPPKDPTLRRLLPDFYR
MLBr_01166|M.leprae_Br4923 HLVGALLGLLNERESSSPLDELEVITGIKAGNAQRPEDPTLRRLLPDFYT
TH_1209|M.thermoresistible__bu NLTTSLLAMLEERESSAPRDELAQLTGMRTGHTTPPPDATLQRLLPDFHR
MAB_1476|M.abscessus_ATCC_1997 SMVTSMLAMLDERESSAPSDELAQLTGIRTGNTEAPTDVTLGRLLPDFHR
:. :::.:*::*::::* *** :**:::*:: * * *: ******.
Mflv_2350|M.gilvum_PYR-GCK PA---TEHPAGSSA-----AESLNSALRSLHEPEILDAKREAAQRLLDTL
Mvan_4295|M.vanbaalenii_PYR-1 PA---TEHPAGSGT-----AESLNSALRSLHEPAILDAKREAAQRLLDTV
MSMEG_4909|M.smegmatis_MC2_155 PQ---TDHPAGSGT-----AESLNSALRGLHEPQIIDAKRQAAQRLLDTM
Mb1367|M.bovis_AF2122/97 PDDLDDDDPTAVDG-----SESFNAALRSLHEPEIIDAKRVAAQQLLDTV
Rv1332|M.tuberculosis_H37Rv PDDLDDDDPTAVDG-----SESFNAALRSLHEPEIIDAKRVAAQQLLDTV
MMAR_4066|M.marinum_M PG---ETDPMTLDS-----SETLNAALRSLHEPDIIDAKRATAQQLLDTV
MUL_3930|M.ulcerans_Agy99 PG---ETDPMTLDS-----SETLNAALRSLHEPDIIDAKRATAQQLLDTV
MAV_1552|M.avium_104 PD---DNGDESPDA-----AESLNAALRSLHEPGIVNAKRVAAQRLLDTV
MLBr_01166|M.leprae_Br4923 PDDKDQLDPAALDA-----VDSLNAALRSLHEPEIVDAKRSAAQQLLDTL
TH_1209|M.thermoresistible__bu PP---GDDPDSADAGSAQDVESLNSALRSLHEPQILDAKRQSAEQLLQTL
MAB_1476|M.abscessus_ATCC_1997 PD---QDGTSSIEA-----VSGLNSALRSLYEPEIIDAKREAGQRLLRTL
* . :*:***.*:** *::*** :.::** *:
Mflv_2350|M.gilvum_PYR-GCK PAAGGKFELSEQDAHAWASAVNDVRLALGTMLDIGADGPDRLPGDHPMSG
Mvan_4295|M.vanbaalenii_PYR-1 PAGGGKFELSEDDAHAWAAAVNDVRLALGTMLDVGSDGPDHLPGDHPMAG
MSMEG_4909|M.smegmatis_MC2_155 PDGGGKFELTEDDAHAWAAAVNDVRLALGTLLEIGPDGPDRLPPEHPMAG
Mb1367|M.bovis_AF2122/97 PDNGGRLELTESDANAWIAAVNDLRLALGVMLEIGPRGPERLPGNHPLAA
Rv1332|M.tuberculosis_H37Rv PDNGGRLELTESDANAWIAAVNDLRLALGVMLEIGPRGPERLPGNHPLAA
MMAR_4066|M.marinum_M PEKGGRFELTEDGANAWVAAVNDLRLTLGVLLDVGPRGPERLPADHPLAA
MUL_3930|M.ulcerans_Agy99 PEKGGRFELTEDGANAWVAAVNDLRLTLGVLLDVGPRGPERLPADHPLAA
MAV_1552|M.avium_104 PDDGGRFELTEDDANAWIAAVNDIRLTLGVMLEIGPDGPERLPADHPLAV
MLBr_01166|M.leprae_Br4923 PESDGRLELTEASANAWIAAVNDLRLALGVILEIDRPAPERVPAGHPLSV
TH_1209|M.thermoresistible__bu PERGGKVDLSEAEAEAWAAAVNDIRLALGTMLGVGPEGPERLPDDHPLAG
MAB_1476|M.abscessus_ATCC_1997 PADGGRFELSETDAQAWLTALNDVRLALGAMLGIDSEGPQELAVDDPMAG
* .*:.:*:* *.** :*:**:**:**.:* :. .*:.:. .*::
Mflv_2350|M.gilvum_PYR-GCK HLDVYQWLTVLQEYLVVSLMGGSR-
Mvan_4295|M.vanbaalenii_PYR-1 HLDVYQWLTVLQEYLVVCLMGNNR-
MSMEG_4909|M.smegmatis_MC2_155 HLDVYQWLTVLQEYLVLELVGK---
Mb1367|M.bovis_AF2122/97 HFNVYQWLTVLQEYLVLVLMGSR--
Rv1332|M.tuberculosis_H37Rv HFNVYQWLTVLQEYLVLVLMGSR--
MMAR_4066|M.marinum_M HYDVYQWLTVLQEYLVLVLMGKSAG
MUL_3930|M.ulcerans_Agy99 HYDVYQWLTVLQEYLVLVLMGKSAG
MAV_1552|M.avium_104 HFDVYQWLTVLQEYLVLVLMGPRSS
MLBr_01166|M.leprae_Br4923 HFDVYQWLTVLQEYLVLALMAT---
TH_1209|M.thermoresistible__bu HHDVYQWLTVLQEYLVLGLLDRPGR
MAB_1476|M.abscessus_ATCC_1997 HMDIYHWLTVMQELLVLALMGKSAV
* ::*:****:** **: *: