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VNRDTVWQHIDEQRTSLADLIDDLGSRGPGVWDTPSLCAGWSVRNVAAHLTHSTMAPPRMLWEAIRSGFR FDAMVDRLALADPRSPAEISAHLRAAVGSRRHPPGTTAFEPLIDVLVHAQDICVPLGIDRPMPVDAAVAA AERVWEMGFPFRARTRLAGVRLVATDADFAVGAGREHAAPVRELLMVLTGRAAAVADAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2303 | - | - | 100% (199) | hypothetical protein Mflv_2303 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2062 | - | 3e-19 | 34.83% (201) | hypothetical protein Mb2062 |
| M. tuberculosis H37Rv | Rv2036 | - | 9e-20 | 35.32% (201) | hypothetical protein Rv2036 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1584 | - | 9e-21 | 34.41% (186) | hypothetical protein MAB_1584 |
| M. marinum M | MMAR_0893 | - | 5e-20 | 33.51% (194) | hypothetical protein MMAR_0893 |
| M. avium 104 | MAV_0227 | - | 1e-16 | 34.04% (188) | hypothetical protein MAV_0227 |
| M. smegmatis MC2 155 | MSMEG_5349 | - | 1e-53 | 52.85% (193) | hypothetical protein MSMEG_5349 |
| M. thermoresistible (build 8) | TH_1248 | - | 5e-16 | 34.24% (184) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0646 | - | 2e-19 | 32.99% (194) | hypothetical protein MUL_0646 |
| M. vanbaalenii PYR-1 | Mvan_4343 | - | 4e-81 | 74.35% (191) | hypothetical protein Mvan_4343 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0227|M.avium_104 -------MTSELMAMARAERADLAEFLATLG---PRDWEAPSLCSRWSVK
TH_1248|M.thermoresistible__bu -----------MMDMAYAERTELAQFLATLT---PEQWATPSLCARWTVK
Mb2062|M.bovis_AF2122/97 MIAADDDTEKSMMDMARAERAELAAFLTTLT---LQQWETPSLCAGWSVK
Rv2036|M.tuberculosis_H37Rv MIAADDDTEKSMMDMARAERAELAAFLTTLT---LQQWETPSLCAGWSVK
MAB_1584|M.abscessus_ATCC_1997 --------MQSAMELARAERIDLADFLAGLT---AEQWDAPSLCTQWRVR
MMAR_0893|M.marinum_M --------MADIWTTIAAERGALADDLATLP---ADRWETPSLCAGWRVR
MUL_0646|M.ulcerans_Agy99 --------MADIWTTIAAERGALADDLATLP---ADRWETSSLCAGWRVR
Mflv_2303|M.gilvum_PYR-GCK ------MNRDTVWQHIDEQRTSLADLIDDLGSRGPGVWDTPSLCAGWSVR
Mvan_4343|M.vanbaalenii_PYR-1 ------MDRDTVWHHIDNQRLELADLIDEIDARDRALWDTPSLCAGWTVR
MSMEG_5349|M.smegmatis_MC2_155 ------MDSDTIWRHVDEQRGQLADLLDTLK---PEQWSTPSLCAGWTVR
:* ** : : * :.***: * *:
MAV_0227|M.avium_104 DVVAHVISYEELGAFGLLKRFAKG--WVVRANQVGVDEFADLTPQQLLEF
TH_1248|M.thermoresistible__bu DVVAHVISYEELGPFGLLKRFAKG--YVVRANQVGVDEFGSLSPEQLLDF
Mb2062|M.bovis_AF2122/97 EVVAHMISYEDLGVFGLLKRFAKG--RIVRANEVGVDEFAGLSPQELVDY
Rv2036|M.tuberculosis_H37Rv EVVAHMISYEDLGVFGLLKRFAKG--RIVRANEVGVDEFAGLSPQELADY
MAB_1584|M.abscessus_ATCC_1997 DVVTHMIGYEDLSRAEFYSRVAKAGFNPNKANANRVAELAGRTPQELLAM
MMAR_0893|M.marinum_M DVVAHLCATASLNPARFFLGMAAAGFSFDRFTNGQLAKHLGPDPAATLDE
MUL_0646|M.ulcerans_Agy99 DVVAHLCATASLNPARFFLGMAAAGFSFDRFTNGQLAKHLGPDPAATLDE
Mflv_2303|M.gilvum_PYR-GCK NVAAHLTHSTMAPPRMLWEAIRSG--FRFDAMVDRLALADPRSPAEISAH
Mvan_4343|M.vanbaalenii_PYR-1 NVAAHLTHSTIGMPRMFFEAARSG--FRFNAVVNRMAVSDDRSPAQIAAN
MSMEG_5349|M.smegmatis_MC2_155 DVAVHVTQVNVSRGEYVRAAIRSG--FRFDAMISRMAVTDTSDPATITAR
:*..*: . . : *
MAV_0227|M.avium_104 LREHLEPRGLTAGFGGMIALVDGTIHHQDIRRALGRPRVVPPDRLQRVLS
TH_1248|M.thermoresistible__bu LNRHLWPRGLTAGFGGMIALVDGTVHHQDIRRPLGRPRTIAADRLLRVLR
Mb2062|M.bovis_AF2122/97 VGRHLQPRGLTAGFGGMIALVDGMIHHQDIRRPLGQPRTIPAQRLDRVLR
Rv2036|M.tuberculosis_H37Rv VGRHLQPRGLTAGFGGMIALVDGMIHHQDIRRPLGQPRTIPAQRLDRVLR
MAB_1584|M.abscessus_ATCC_1997 VRAAQTPGVLTSGFGGRIALLDGIIHQQDIRRPLGMPRQIPGDRLTVAMD
MMAR_0893|M.marinum_M FRGLQHATSAPPGPK-VSWLGEIVLHGADIRQPLGIPHTYSPGALRQTID
MUL_0646|M.ulcerans_Agy99 FRGLQHATSAPPGPK-VSWLGEIVLHGADIRQPLGIPHTYSPGALRQTID
Mflv_2303|M.gilvum_PYR-GCK LRAAVGSRRHPPGTTAFEPLIDVLVHAQDICVPLGIDRPMPVDAAVAAAE
Mvan_4343|M.vanbaalenii_PYR-1 LRAVVGSRRHPPGTTERDPLTDVLVHTQDICVPLGIDRPMPVDAAVAAAE
MSMEG_5349|M.smegmatis_MC2_155 LRAIVGDRGRPPFTKEVDPLMDVLVHTQDICVPLGIEHPMPVDAAVAVAQ
. .. * : :* ** .** : . .
MAV_0227|M.avium_104 LVPGNPRLG-AGRRIRGLRLRATDIDWTHG--DGPQVSGPGEALLMAMSG
TH_1248|M.thermoresistible__bu SVPGNPRLG-AGRRIRGLRLHATDIDWTHG--EGPEVSGTGEALLMAMTG
Mb2062|M.bovis_AF2122/97 LMPKNPRLR-ARPRIKGLRLRATDLDWTIG--TGPEVTGPGEALLMAMAG
Rv2036|M.tuberculosis_H37Rv LMPKNPRLR-ARPRIKGLRLRATDLDWTIG--TGPEVTGPGEALLMAMAG
MAB_1584|M.abscessus_ATCC_1997 FARWAPPVR-GALRARGVRLVATDLDWSRG--SGPEVTGPAEALLMAMAA
MMAR_0893|M.marinum_M FYRGSNLLSGAKKRISGLELCATDDDWRHG--QGERVEGPLLSLLLAMTG
MUL_0646|M.ulcerans_Agy99 FYRGSNLLSGAKKRISGLQLCATDDDWRHG--QGERVEGPLLSLLLAMTG
Mflv_2303|M.gilvum_PYR-GCK RVWEMGFPFRARTRLAGVRLVATDADFAVG--AGREHAAPVRELLMVLTG
Mvan_4343|M.vanbaalenii_PYR-1 RVWNADFPFHARKRLAGTRLVATDADFTVG--EGREVAAPISALLMLLTG
MSMEG_5349|M.smegmatis_MC2_155 RLWGMKFPLNPQRDLPGYRFVATDAGFTAGPEWGALREATIHDIVLMLSR
* .: *** .: * * .. ::: ::
MAV_0227|M.avium_104 RPAALADLDGPGRATLAARLGQ-
TH_1248|M.thermoresistible__bu RAAVVDELGGPGKPVLAGRLR--
Mb2062|M.bovis_AF2122/97 RPAAVSDLSGPGKPTLAGRLG--
Rv2036|M.tuberculosis_H37Rv RPAAVSDLSGPGKPTLAGRLG--
MAB_1584|M.abscessus_ATCC_1997 RPCALAELEGPGKSTLAQHIS--
MMAR_0893|M.marinum_M RAAGCVDLTGPGAQLLRSRCSGT
MUL_0646|M.ulcerans_Agy99 RAAGCVDLTGPGAQLLRSRCSGT
Mflv_2303|M.gilvum_PYR-GCK RAAAVADAR--------------
Mvan_4343|M.vanbaalenii_PYR-1 RE---------------------
MSMEG_5349|M.smegmatis_MC2_155 RLSIPDSEPDPDE----------
*