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SRTVHTFCRYCLASCGVEVTVEDNRVTKISADKRNPHSWHDFCAKGRTAAQLVEHPRRILNPMRRVGDEY VEAGWDEAIADIATRMNAAIDAGGPDAVGVYYGNPAGFSSSNIVFMNGWLDAVGTHSRYAVGSIDQNAMH VVAQAMYGSILMAPVSDIDNCDYFLLVGTNPAVSAWNWLETVPGGWRRALARQARGATIVVVDPVRTESA AKADVHVAVRPGQDWALLLAMVAVILGEGLEHRQDCAELVDSMEGLRALVVDVDIDDLADRCDVPRDRIE SVARDFATARAAMVVTRTGLSMHLTGTVAEWLGHVLNVITGRMDRPGGRRYEPGYVDAIRMSGMVKATPH RNRLSGREMVAGAHALSELPDEITTPGPGQIRALLLNCGNPVVSGPDGARLDEALSQLDLLVAIDFVQRE SHRHAHWLLPAVHWLERDDLLAFTSNMHDEPYLHFGARTVEPPPGARQEWRIFVDLALAMGKPLFRAKGL NAFITATRRVARVTRRPQLEFSPAWIDRLVVATGRKFNGRRIRWREVLAHPHGWVLGPREFGHFREALRT PDKVVRLAPPEFVARARELLAEPAPAAPAGYPFQLANRRHRHSMNSWLNDLPGLHPSGKGSEVVLHPYDA APLGIADGDRVTVHSPVGAIELTAAVSDQPRPGVVIIDHGWGSRVFDPRGGSAPVGFGVNRNLLVDAEEV DPLSQTPALNSAYVAVTRV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2249 | - | - | 100% (720) | formate dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4342 | - | 9e-94 | 32.40% (713) | molydopterin dinucleotide-binding region |
| M. gilvum PYR-GCK | Mflv_1413 | - | 2e-88 | 33.77% (758) | molydopterin dinucleotide-binding region |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0203 | - | 6e-54 | 26.32% (756) | oxidoreductase |
| M. tuberculosis H37Rv | Rv0197 | - | 1e-53 | 26.32% (756) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3870c | - | 9e-85 | 32.97% (725) | molybdopterin oxidoreductase |
| M. marinum M | MMAR_2605 | - | 4e-81 | 31.52% (755) | anaerobic dehydrogenase |
| M. avium 104 | MAV_4983 | - | 1e-49 | 25.13% (748) | molybdopterin oxidoreductase Fe4S4 subunit |
| M. smegmatis MC2 155 | MSMEG_2237 | - | 7e-80 | 30.82% (743) | anaerobic dehydrogenase, typically |
| M. thermoresistible (build 8) | TH_4483 | - | 0.0 | 73.88% (716) | PUTATIVE Formate dehydrogenase |
| M. ulcerans Agy99 | MUL_1474 | fdhF | 6e-43 | 25.68% (767) | formate dehydrogenase H FdhF |
| M. vanbaalenii PYR-1 | Mvan_4442 | - | 0.0 | 79.55% (719) | molydopterin dinucleotide-binding region |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2249|M.gilvum_PYR-GCK ---------MSRTVHTFCRYCLASCGVEVTVE------DNRVTKISADKR
Mvan_4442|M.vanbaalenii_PYR-1 ---------MSRTVHTFCRYCLAACGVEVTVE------GNRVVKISADKQ
TH_4483|M.thermoresistible__bu ----------MTTVHTFCRYCLAACGVEVTVE------DNRVVNISADRA
MAB_3870c|M.abscessus_ATCC_199 --------------------------MVATVE------GGKLLSLRPDKD
MSMEG_2237|M.smegmatis_MC2_155 MVIESGAGHKPEHKVTFCRICEPLCGMIATVE------DGRLTALRPDRD
MMAR_2605|M.marinum_M -----MATVDDGRHLHTCPLCEAMCGLEIRVADG--PSGGRVVGIRGNRD
Mb0203|M.bovis_AF2122/97 -------MTSSDWLPTACILCECNCGIVVQVD------DRRLARIRGDKA
Rv0197|M.tuberculosis_H37Rv -------MTSSDWLPTACILCECNCGIVVQVD------DRRLARIRGDKA
MAV_4983|M.avium_104 -------MTG-EWQPSACILCECNCGIVVQVE------DRRLARIRGDKA
MUL_1474|M.ulcerans_Agy99 ------MAPNKDAVKTVCAYCGVGCGIVLQTTTDPQTGKRRVAKSTGDKS
: . :: ::
Mflv_2249|M.gilvum_PYR-GCK NPHSWHDFCAKGRTAAQLVEHPRRILNPMRRVGDE------------YVE
Mvan_4442|M.vanbaalenii_PYR-1 NPHSWQDFCAKGRTAHQVVEHPRRIVAPMKRVGDR------------YVE
TH_4483|M.thermoresistible__bu NPHTWHDFCAKGRTAHQVVEHPRRILAPMRRVGDR------------YVE
MAB_3870c|M.abscessus_ATCC_199 NPASSGFSCQKGIAFADVHNDPDRLTTPMRRTVSG-----------EFEP
MSMEG_2237|M.smegmatis_MC2_155 HPLSAGFACQKGIAFAEVVNDPDRITTPLRRRADAKRPGNRTDVLDGFEP
MMAR_2605|M.marinum_M DVWSRGHICPKGASLGALHDDPDRIRHPMIKIDGQ------------WHE
Mb0203|M.bovis_AF2122/97 HPGSAGYTCNKALRLDHYQNNRARLSSPMRRRADG-----------TYEE
Rv0197|M.tuberculosis_H37Rv HPGSAGYTCNKALRLDHYQNNRARLSSPMRRRADG-----------TYEE
MAV_4983|M.avium_104 HPASQGYTCNKVLRLDHYQNSRARLTSPLRRRPDG-----------SYEE
MUL_1474|M.ulcerans_Agy99 HPANLGRLCTKGTTTADLLAAPGRMESAHLRAHRAG----------HLES
. . * * *: . :
Mflv_2249|M.gilvum_PYR-GCK AGWDEAIADIATRMNAAIDAGGPDAVGVYYGNPAGFSSSNIVFMNGWLDA
Mvan_4442|M.vanbaalenii_PYR-1 TSWDEAIDDIAARLNAAIDADGPDAVGAYYGNPAGYSSSNLMFMNGWLDA
TH_4483|M.thermoresistible__bu ADWDEAITDIATRLNALIDADGPDAIGLYYGNPTGYSTSNLIFMNAWLDA
MAB_3870c|M.abscessus_ATCC_199 VEWDTAMADIAERVRAIHRMHGSGAIGWYFGNPGAFSYSHVLWLLLLSMG
MSMEG_2237|M.smegmatis_MC2_155 VGWDEALDDIAHRLSGIHRRHGSGAVAWYMGNPAAFSYSHLFAAMAFAKG
MMAR_2605|M.marinum_M VSWDAAFRRCTELLAPVIDTYGIGAVTAYTGNPLAHSFS-LARYAGVLLG
Mb0203|M.bovis_AF2122/97 IDWDTAIVEIAEGFKQIRDTHG-GDKIFYYGGGGQGNHLGGAYSGAFLKA
Rv0197|M.tuberculosis_H37Rv IDWDTAIVEIAEGFKQIRDTHG-GDKIFYYGGGGQGNHLGGAYSGAFLKA
MAV_4983|M.avium_104 IDWDTAIVEIAEGFKRIRDSYG-GDKIFYYGGGGQGNHLGGAYSGAFLKA
MUL_1474|M.ulcerans_Agy99 IPIDDAITQCAMRLRAIIDEHGPDAVGVYVSG--QMSIEAQYLANKLTKG
* *: : . * . * .. . .
Mflv_2249|M.gilvum_PYR-GCK VG-THSRYAVGSIDQNAMHVVAQAMYGS-ILMAPVSDIDNCDYFLLVGTN
Mvan_4442|M.vanbaalenii_PYR-1 VG-TFNRYAVGSVDQNAMHVVAEKMYGS-ALLAPVSDVDNCDFFLLIGAN
TH_4483|M.thermoresistible__bu VG-TNNRYAVGSVDQNALHVVAEAMYGS-PIMVPVSDVDNCDYFLIVGAN
MAB_3870c|M.abscessus_ATCC_199 FGSRLHLFTAGSQDINSRFVASQLLYGN-SATMPVPDIPRTDLLVVIGAN
MSMEG_2237|M.smegmatis_MC2_155 IGGDSHFFSSSTQDTSSRLLANQFLYGA-PFPVPIPDVMRTDLLVMIGAN
MMAR_2605|M.marinum_M MSGMPVTYSPGTVDQWPKNLSSHLMYGG-WWTFPVPDIERTDLLVIMGAN
Mb0203|M.bovis_AF2122/97 LG-SRYRSNALAQEKTGEAWVDFQLYGG-HTRG---EFENAEVSVFVGKN
Rv0197|M.tuberculosis_H37Rv LG-SRYRSNALAQEKTGEAWVDFQLYGG-HTRG---EFENAEVSVFVGKN
MAV_4983|M.avium_104 LG-SRYRSNALAQEKTGESWIDGQLYGG-HTRG---EFEHAEVAVFVGKN
MUL_1474|M.ulcerans_Agy99 FIGTKQIESNSRLCMAGASSGYKLSLGADGPPGSYQDFDHADVFLVIGAN
. * :. . : :.:* *
Mflv_2249|M.gilvum_PYR-GCK PAVSAWNWLETVPGGWRRALARQARGATIVVVDPVRTESAAKADVHVAVR
Mvan_4442|M.vanbaalenii_PYR-1 PAVSAWNWLESVPGGWRRALARQQQGATLVVVDPLRTESAGKADVHVAVR
TH_4483|M.thermoresistible__bu PAVSAWNWVESVPDGWRRALRRQRAGATIVVVDPIRTETADRADIHLAVR
MAB_3870c|M.abscessus_ATCC_199 PVVSHGSGVTMP--RIREHMKAVVKRGGRVLVIDPRKTETAADFEWLGIA
MSMEG_2237|M.smegmatis_MC2_155 PVVSHGSFLTAP--RLKDRMHDIVKRGGRVVVVDPRRSETAAQFEWLGIV
MMAR_2605|M.marinum_M PAASQGSLLAAP--DVMGLIDAIRQRGKVIVIDPVRTVTAARADEWLPIV
Mb0203|M.bovis_AF2122/97 PWMSQS----FPRARVVLNEIAKDPGRSMIVIDPVVTDTAKMADFHLRVQ
Rv0197|M.tuberculosis_H37Rv PWMSQS----FPRARVVLNEIAKDPGRSMIVIDPVVTDTAKMADFHLRVQ
MAV_4983|M.avium_104 PWMSQS----FPRARVVLNEIAKDPARSMIVIDPVVTDTAKMADFHLRVR
MUL_1474|M.ulcerans_Agy99 MADCHP-------ILFLRMMERVKSGAKLIVVDPRRTATADKADLFLQIA
. ::: : : :
Mflv_2249|M.gilvum_PYR-GCK PGQDWALLLAMVAVILGEGLEHRQDCAELVDSMEGLRALVVDVDIDDLAD
Mvan_4442|M.vanbaalenii_PYR-1 PGQDWALLLAMVKVILDGGLEHRGDCSDLAVGVDRLRTLVAEADLDDLAM
TH_4483|M.thermoresistible__bu PGQDWALLLAMVKIILDEGLEHRGDCTELATGVPRLRELVAAADLDDLAA
MAB_3870c|M.abscessus_ATCC_199 PDGDAFLLLSLLQVMFTENLVDRALVAQHARGVAWLEGLVRPFTPESTQA
MSMEG_2237|M.smegmatis_MC2_155 PDTDAYFLLSLLQVMFDENLVA-PRAATQADGLDWLRRQSAPFTPESTRA
MMAR_2605|M.marinum_M PGTDAALLLAVAHTLFDEDLVN---PGPHVDGVDTMRRVAADWPPARVSA
Mb0203|M.bovis_AF2122/97 PGCDAWCLAALAAVLVQENLCNEAFLAAHVHGVDTVRAALQEVPVADYAQ
Rv0197|M.tuberculosis_H37Rv PGCDAWCLAALAAVLVQENLCNEAFLAAHVHGVDTVRAALQEVPVADYAQ
MAV_4983|M.avium_104 PGTDAWCLAALAAVLVQENLCDEAFLAEHVRCADAVRHALRDVAVSEYAA
MUL_1474|M.ulcerans_Agy99 PGTDLALLNGLLHLIVENEQTDPQFISEFTEGWEVMPSFLEQFTPDRVSE
*. * * .: :. . :
Mflv_2249|M.gilvum_PYR-GCK RCDVPRDRIESVARDFATARAAMVVTRTGLSMHLTGTVAEWLGHVLNVIT
Mvan_4442|M.vanbaalenii_PYR-1 RCDVARTQIVDVATAFATSPRAMAVTRTGVSLHLAGTVAEWLGHVLNVIT
TH_4483|M.thermoresistible__bu RCDVPRTQIERVARGFATARTAMAVTRTGVSLHATGTVGEWLGHVLNVIT
MAB_3870c|M.abscessus_ATCC_199 QTGVDPGVVRQLARDLAGADRAVVYGRVGTCLGQNGTLTTYLLDVVNLVA
MSMEG_2237|M.smegmatis_MC2_155 HTGVEPETLRALARDLAGTARAAVYGRLGTCVGRHGTLTTYLIDAVNIVA
MMAR_2605|M.marinum_M VTGIEEERIRRLARELAGTHKSVVYGRIGLCNQEFGSLASWLVDVINILT
Mb0203|M.bovis_AF2122/97 RCGVDEELLRAAARRIGTAASVSVFEDLGIQQAPNSTVCSYLNKLLWILT
Rv0197|M.tuberculosis_H37Rv RCGVDEELLRAAARRIGTAASVSVFEDLGIQQAPNSTVCSYLNKLLWILT
MAV_4983|M.avium_104 HCGVDEELLRTAARRIGTADSVAVFEDLGVQQAPNSTLCSYLNKLLWILT
MUL_1474|M.ulcerans_Agy99 ITGIPSEDIRTAARWIGTAANWMSCWTMGLNQSTHGTWNTNALCNLHLAT
.: : * :. : * .: : : :
Mflv_2249|M.gilvum_PYR-GCK GRMDRPGGRRYEPGYVDAIRMSGMVKAT-------PHRNRLSGREMVAGA
Mvan_4442|M.vanbaalenii_PYR-1 GRMDRPGGRRFEPGYVDALRLAELAGTK-------PHTSRLRGRPLVAGA
TH_4483|M.thermoresistible__bu GRMDRPGGRRFERGYVDAQRLTALVKPP-------AHRSRVHGRPMVAGA
MAB_3870c|M.abscessus_ATCC_199 GHLGRVGGSMFGSFGIPGERFAMKAVGALLGAVYRRRRSRVGGFPSVLGS
MSMEG_2237|M.smegmatis_MC2_155 GNLDVPGGSVFSTLGMPGQRWGSMAMGASLRRSYRTRRTRVGGFKSVIGA
MMAR_2605|M.marinum_M GHFDTPGGAMFPRPAAWSITTQPLPGLEGGVAEFGRWHTRVRGAKEVLGQ
Mb0203|M.bovis_AF2122/97 GNFAKKGGQHLHSSFAPLFSQVSG-------------RTPVTGAPIIAGL
Rv0197|M.tuberculosis_H37Rv GNFAKKGGQHLHSSFAPLFSQVSG-------------RTPVTGAPIIAGL
MAV_4983|M.avium_104 GNFAKRGGQHLHSSFAPLFGQFSG-------------RTPVTGAPIISGL
MUL_1474|M.ulcerans_Agy99 GAICRPGSGPFSLTGQPNAMGGREMGYMG---------PGLPGQRSVLSA
* : *. : * : .
Mflv_2249|M.gilvum_PYR-GCK HALSELPDEITTPG-------------------PGQIRALLLNCGNPVVS
Mvan_4442|M.vanbaalenii_PYR-1 HALSELPDEITTPG-------------------RGQIRALIVNSGNPVIS
TH_4483|M.thermoresistible__bu HALAELPDEITTPG-------------------PGRIRALVINSGNPVVS
MAB_3870c|M.abscessus_ATCC_199 EPAGIMAKEITTPG-------------------RGQIRALFVGAGNPVLS
MSMEG_2237|M.smegmatis_MC2_155 EPAALMAKEITTPG-------------------RRQVKAMFIGAGNPVLS
MMAR_2605|M.marinum_M APVSCLAEEIATPG-------------------DGQLRALITIAGNPVLS
Mb0203|M.bovis_AF2122/97 IPGNVVPEEILTEH-------------------PDRFRAMIVESGNPAHS
Rv0197|M.tuberculosis_H37Rv IPGNVVPEEILTEH-------------------PDRFRAMIVERGNPAHS
MAV_4983|M.avium_104 VPSNVVPEEILTDH-------------------PDRFRAMIVESSNPAHS
MUL_1474|M.ulcerans_Agy99 PDREFVEEQWGLPGGALRTDVSGGVIDMFSRMADGEIKACWIICSNPVAT
: .: ..:* .**. :
Mflv_2249|M.gilvum_PYR-GCK GPDGARLDEALSQLDLLVAIDFVQR-ESHRHAHWLLPAVHWLERDDLLAF
Mvan_4442|M.vanbaalenii_PYR-1 GPDGAKLDHALSQLDLLVAIDFVQR-ESHRHAHWLLPAVHWLERDDLLAF
TH_4483|M.thermoresistible__bu GPDGARLDAALAQLDLLVAIDLVQR-ESHRHAHWLLPAVHWLERDDLLAL
MAB_3870c|M.abscessus_ATCC_199 VPNGDELEAACEQLDLMVGIDLYLN-ETLAHCHYVLPATTMYERDDFMIP
MSMEG_2237|M.smegmatis_MC2_155 VPNGPELAEALDAAELTVGLDLYVN-ETTAHCDYVLPVTTMYERDDFAVT
MMAR_2605|M.marinum_M TPGGDKLDEALSSLEAMISVDLWLN-ETTRHADVILPGLSPLEQPHHDDL
Mb0203|M.bovis_AF2122/97 LADSAACRAAFQALELMVVVDVAMT-ETARLAHYVLPAASQFEKPEATFF
Rv0197|M.tuberculosis_H37Rv LADSAACRAAFQALELMVVVDVAMT-ETARLAHYVLPAASQFEKPEATFF
MAV_4983|M.avium_104 LANSAACREAFASLELMVVIDVAMT-ETARLAHYVLPAASQFEKPEATFF
MUL_1474|M.ulcerans_Agy99 VANRKTVLAGLEKAELVISQDAFFETETNEYANVLLPAALWTESDGVMVN
.. . : : * *: .. :** *
Mflv_2249|M.gilvum_PYR-GCK TSNMHDEPYLHFGARTVEPPPGARQEWRIFVDLALAMGKPLFRAKG----
Mvan_4442|M.vanbaalenii_PYR-1 TSSLHDEPYLHYGVRAVDPPAQARQEWRIFVDLALAMNRPLFGVPG----
TH_4483|M.thermoresistible__bu TSGMHDEPYAQYGVRAVDPPPRAREEWRIFVDLALAMGRPLFGVRG----
MAB_3870c|M.abscessus_ATCC_199 FATLRPAPYRQATEAVVAPAGQARQEWQIIEDLTSRLWNLTPG-------
MSMEG_2237|M.smegmatis_MC2_155 FQMFQATPFRQATEAMVAPRGQARTEWDIVVDLIGRMSVRTPV-------
MMAR_2605|M.marinum_M VLQFAIRSFANYSAPVFDP-GDRPHEWEILIRLTGLCTGTPAEDVDVAAI
Mb0203|M.bovis_AF2122/97 NFEFPRNGFQLR-RPLFPPLPGTLPEPEIWARLVRALGVVDEADLRPLRE
Rv0197|M.tuberculosis_H37Rv NFEFPRNGFQLR-RPLFPPLPGTLPEPEIWARLVRALGVVDEADLRPLRE
MAV_4983|M.avium_104 NLEFPRNTFQLR-RPLLTPLPGTLPEPEIWARLVRALGVVTEADLRPLHD
MUL_1474|M.ulcerans_Agy99 CERN-----MSLFPKAVDPVGDALPDWQIIARIACEMGFSESFSYSSAAE
. * : * :
Mflv_2249|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4442|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAB_3870c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_2237|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2605|M.marinum_M DD------------------------------------------------
Mb0203|M.bovis_AF2122/97 AAAQGR--------------------------------------------
Rv0197|M.tuberculosis_H37Rv AAAQGR--------------------------------------------
MAV_4983|M.avium_104 AARRGR--------------------------------------------
MUL_1474|M.ulcerans_Agy99 VFEEIKRFSNPATGYDLRGISHDRLRETPLQWPCPPDGASNRSPIRYLND
Mflv_2249|M.gilvum_PYR-GCK ---------------LNAFITATRRVARVTR--RPQLEFS----------
Mvan_4442|M.vanbaalenii_PYR-1 ---------------LNRFVRASRRLARLTR--RPGLEFG----------
TH_4483|M.thermoresistible__bu ---------------INEFVTATRWLALRTG--RPGVAFG----------
MAB_3870c|M.abscessus_ATCC_199 ----------------LRFIEGLRRTVALF-----GARLQ----------
MSMEG_2237|M.smegmatis_MC2_155 ----------------FAMLRCAQKLAGRR-----GRRLN----------
MMAR_2605|M.marinum_M -----------GFFDYLAFTKGFDGAAIRKRYEHDGWAGG----------
Mb0203|M.bovis_AF2122/97 ----------QAYTEAFLAAAATNPTVAKLTAYVLYETLG----------
Rv0197|M.tuberculosis_H37Rv ----------QAYTEAFLAAAATNPTVAKLTAYVLYETLG----------
MAV_4983|M.avium_104 ----------HAYTEAFLTAVSTNPTVAQLLPFVLYETLG----------
MUL_1474|M.ulcerans_Agy99 GVSQLQFVRADGTVPRLAFPTATGRAVFFARPHLVPDEMPDGDYPFLLNT
.
Mflv_2249|M.gilvum_PYR-GCK -------------------PAW------------IDRLVVATGRKFNGRR
Mvan_4442|M.vanbaalenii_PYR-1 -------------------PRW------------VDRLIVATGRKVNGRR
TH_4483|M.thermoresistible__bu -------------------PHW------------LDRLMVATSRKINGHR
MAB_3870c|M.abscessus_ATCC_199 -------------------PRL------------LADALIRMSAGGDLFR
MSMEG_2237|M.smegmatis_MC2_155 -------------------PRP------------LIDGMIRMADGGDRFG
MMAR_2605|M.marinum_M -------------------PER------------ILDLTLRTGPFGDRYG
Mb0203|M.bovis_AF2122/97 -------------------PTLPDGLAGAAALWGLAQKTAMAYPDAVRRA
Rv0197|M.tuberculosis_H37Rv -------------------PTLPDGLAGAAALWGLAQKTAMAYPDAVRRA
MAV_4983|M.avium_104 -------------------PTLPDGLRGAAALWGLAQKTALTYPEAVRRA
MUL_1474|M.ulcerans_Agy99 GRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDDAADMQICEGDHIEIAS
Mflv_2249|M.gilvum_PYR-GCK IR------WREVLAHPHGWVLGPREFG-HFREALRTPDKV-------VRL
Mvan_4442|M.vanbaalenii_PYR-1 IR------WRDVLGHPHGWVLGPREFG-HFREALRTPDKL-------VHV
TH_4483|M.thermoresistible__bu LT------WRDLREHPHGLVLGPREFG-HFRSALRTPDKK-------VHT
MAB_3870c|M.abscessus_ATCC_199 LRRQGLTFDRLTRDYPHGKVLAEHLPEVPLSRSVSYLDGR-------MRL
MSMEG_2237|M.smegmatis_MC2_155 LRRDGLTFRKLAEEHPHGVIVAPHVRTGVLGEVVVYPKGR-------VRL
MMAR_2605|M.marinum_M QNPGGLTLDMLKAN-PNGIDFGPMVS--QLPDILGTPEKK-------IRL
Mb0203|M.bovis_AF2122/97 GHADGNALFDAILERPSGVTFTVHNYEDDFALIS-HPDHK-------IAL
Rv0197|M.tuberculosis_H37Rv GHADGNALFDAILERPSGVTFTVHNYEDDFALIS-HPDHK-------IAL
MAV_4983|M.avium_104 GHADGNALFDAILDNPSGVTFTVHDYADDFTLIG-HPDHK-------IAL
MUL_1474|M.ulcerans_Agy99 RRGRAVLPVVITDRVRPGNCFAPFHWNDAFGEYLSINAVTNDAVDPISRQ
* . :
Mflv_2249|M.gilvum_PYR-GCK APPEFVARARELLAEPAPAAPAGYPFQLANRRHR--------HSMNSWLN
Mvan_4442|M.vanbaalenii_PYR-1 APPEFLARARELLAEPVPQPPSGYPFQLANRRNR--------HSMNSWLN
TH_4483|M.thermoresistible__bu APPEFIARVRELLAEPHPQAPPGYPFVLGNRRRR--------HSMNSWLN
MAB_3870c|M.abscessus_ATCC_199 EHKDIESEVASLAAR---EHDPRFPMRLIGMREA--------RSENSWMH
MSMEG_2237|M.smegmatis_MC2_155 EHADIATEITALTRR---RNPDGFGLRMIGMREP--------RSENSWMH
MMAR_2605|M.marinum_M APQYLLDDLPRLASR---MDRPAEQLVLVNRRHL--------RSNNSWLH
Mb0203|M.bovis_AF2122/97 EIPEMLAEIRSLTQTPSRLTTPQLPIVLSVGERR--------AYTANDIF
Rv0197|M.tuberculosis_H37Rv EIPEMLAEIRSLTQTPSRLTTPQLPIVLSVGERR--------AYTANDIF
MAV_4983|M.avium_104 EIPAMLQELAKLSSGPPRLTTEEFPIVLSVGERR--------AYTANDIF
MUL_1474|M.ulcerans_Agy99 PEYKACAVTLTKVARPQLQPEPGEPADACADATAPKLLADTAQFSVTQVD
. :
Mflv_2249|M.gilvum_PYR-GCK DLPGLHPSGKGSEVVLHPYDAAPLG-------------IADGDRVTVHSP
Mvan_4442|M.vanbaalenii_PYR-1 DLPGLHPSGKGSEVVIHPDDAARLG-------------IRDGDRVRVSSP
TH_4483|M.thermoresistible__bu ELPDLHPGGRQNTAILHPDDAATLG-------------IADGDRVRLSSP
MAB_3870c|M.abscessus_ATCC_199 NVPMLMRGGRVQRALIHAYDADQLG-------------VTTDDLLAITSP
MSMEG_2237|M.smegmatis_MC2_155 NAPLLMRGQRIQRAFLHADDATARG-------------VRDGDVVRVRSP
MMAR_2605|M.marinum_M NVPALMKGKDRCTLLMHPDDAARNG-------------ITDNDTVTVRSS
Mb0203|M.bovis_AF2122/97 RDPSWRKRDANGALRVSVEDAQALG-------------LADGCLARITTA
Rv0197|M.tuberculosis_H37Rv RDPSWRKRDANGALRVSVEDAQALG-------------LADGCLARITTA
MAV_4983|M.avium_104 RDPSWRKRDAEGALRVSVEDAQALG-------------LADGCRARISTA
MUL_1474|M.ulcerans_Agy99 ALAELLGVGNEPTPQFGPSARSYLAGLIAGLRSETGRRMAGVSTLPISSP
. . . : : :.
Mflv_2249|M.gilvum_PYR-GCK VG-------AIELTAAVSDQPRPGVVIIDHGWGSRVFDPRGGSAPV-GFG
Mvan_4442|M.vanbaalenii_PYR-1 VG-------AVELGASVSDQPRPGVVVIDHGWGSRVFDPRGGADPQ-GYG
TH_4483|M.thermoresistible__bu VG-------VVEAEANLSDRPRRGLVILDHGWGSRVFDPSGHHPPQ-SYG
MAB_3870c|M.abscessus_ATCC_199 HG-------EIELPAQVSKDILPGVVAVPHGWGHRRRAGWSTANANPGAN
MSMEG_2237|M.smegmatis_MC2_155 FG-------QIDIAVSLTTDLVRGTVAIPHGWGHNGSGGWRIANRAGGAN
MMAR_2605|M.marinum_M AG-------EITVPVELTSAIKPGVVSMPHGWGHG-KPGTRLAVANSAPG
Mb0203|M.bovis_AF2122/97 AG-------SAEATVEVTETMLAGHAALPNGFGLDYTGDDG---RTVVAG
Rv0197|M.tuberculosis_H37Rv AG-------SAEATVEVTETMLAGHAALPNGFGLDYTGDDG---RTVVAG
MAV_4983|M.avium_104 AG-------SAEATVEISETMLAGHAALPNGFGLDYVGDDG---RTVVPG
MUL_1474|M.ulcerans_Agy99 FDTGTRLWLDGLLAGMFARAETPPALPFPQTPGAAAQSDNAAEAAVEQPP
. .: . : *
Mflv_2249|M.gilvum_PYR-GCK VNRNLLVDAEEVDPLSQTPALNSAYVAVTRV-------------------
Mvan_4442|M.vanbaalenii_PYR-1 VNRNLLVDGDPVDPLSQTAALNSSYVAVTRA-------------------
TH_4483|M.thermoresistible__bu VNRNLLVDAS-IDPLSQTSTLGTANVAIERSGA-----------------
MAB_3870c|M.abscessus_ATCC_199 VNLLMSSRPEDLEALAGMAHLNGVPVRVQRA-------------------
MSMEG_2237|M.smegmatis_MC2_155 VNELMSSDPRDVEALAGMSWLTGVPVEVETCHLHCESVGVAAGGSSG---
MMAR_2605|M.marinum_M VNTNVLSPPTLLDEPSGNGVLNGIPVTVS---------------------
Mb0203|M.bovis_AF2122/97 VAPNALTSTRWRDPYAGTPWHKHVPAAIRRADAESPIW------------
Rv0197|M.tuberculosis_H37Rv VAPNALTSTRWRDPYAGTPWHKHVPAAIRRADAESPIWYPKWAILPARGV
MAV_4983|M.avium_104 VAPNALTSTQWRDPYAGTPWHKHVPARIEALADARR--------------
MUL_1474|M.ulcerans_Agy99 IVVLWASQTGTAEELAASVAAQLSAAELPVVLHGMDEFAVADLVSTQRLL
: : : . :
Mflv_2249|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4442|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAB_3870c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_2237|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv LA------------------------------------------------
MAV_4983|M.avium_104 --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 LVTSTTGDGEPPDNGAAFWRELCAPTAPSLAGTRYSVLALGDSNYADFCG
Mflv_2249|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4442|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAB_3870c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_2237|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4983|M.avium_104 --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 HGRALDHRLAELGASRITDRVDCEPDYEESAARWLQEVLDGLRRTAPPVI
Mflv_2249|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4442|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAB_3870c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_2237|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4983|M.avium_104 --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 TAEPVRAASIASRPQGYTKKRPLLTSVMRNTTLSRPRSAKDVRQLVFRVP
Mflv_2249|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4442|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAB_3870c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_2237|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4983|M.avium_104 --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 EQTVSYEAGDALGVWPRNAHQLVDEWLGVTRLDGHTEVEVAGHGTMSLRA
Mflv_2249|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4442|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAB_3870c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_2237|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4983|M.avium_104 --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 ALTDRFEIAHLSPDLLRFVAQRTLDSNTANQLAELMRPENKAALADWTWG
Mflv_2249|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4442|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAB_3870c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_2237|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4983|M.avium_104 --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 RQSVDLLAQSPVRASVDEWMSVLKPIQPRLYSISSSPKEHPGEVHLTVSP
Mflv_2249|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4442|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAB_3870c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_2237|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4983|M.avium_104 --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 VRYNFQGVPRRGVCSTYLADRSPSDQIAIYVRKSSNFRPPSDPRTPMIMI
Mflv_2249|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4442|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAB_3870c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_2237|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4983|M.avium_104 --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 GPGTGIAPFRGFLQERRALGHTGPNWLFFGEQHAATDFYYRDEIQAMHRD
Mflv_2249|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4442|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAB_3870c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_2237|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4983|M.avium_104 --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 GLLTNLDLAFSRDQRDKVYVQHLMQQRGAQLWQWLQDGAQVYVCGTADPM
Mflv_2249|M.gilvum_PYR-GCK -----------------------------------------
Mvan_4442|M.vanbaalenii_PYR-1 -----------------------------------------
TH_4483|M.thermoresistible__bu -----------------------------------------
MAB_3870c|M.abscessus_ATCC_199 -----------------------------------------
MSMEG_2237|M.smegmatis_MC2_155 -----------------------------------------
MMAR_2605|M.marinum_M -----------------------------------------
Mb0203|M.bovis_AF2122/97 -----------------------------------------
Rv0197|M.tuberculosis_H37Rv -----------------------------------------
MAV_4983|M.avium_104 -----------------------------------------
MUL_1474|M.ulcerans_Agy99 AKDVDRMLCQIVAEHGGLDPESATAFVHALSADKRYHRDVY