For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AAPILQAEIDINAPVSKVWELVADLKKMSQWSPQCRVMKPLGTLRPGTRTINLNRRGPLFWPTTCRITEF VPEQKLGFRVNENNTVWTYELEPTEAGTRLVETRHAENGTSAVSNFLVGKFMGGVPSFEQELIEGMNASL QRIKAAAEK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1713 | - | - | 100% (150) | cyclase/dehydrase |
| M. gilvum PYR-GCK | Mflv_2072 | - | 1e-06 | 28.57% (98) | hypothetical protein Mflv_2072 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1915c | - | 6e-09 | 29.80% (151) | hypothetical protein Mb1915c |
| M. tuberculosis H37Rv | Rv1883c | - | 9e-07 | 29.14% (151) | hypothetical protein Rv1883c |
| M. leprae Br4923 | MLBr_02031 | - | 5e-10 | 27.52% (149) | hypothetical protein MLBr_02031 |
| M. abscessus ATCC 19977 | MAB_0877c | - | 1e-32 | 46.62% (148) | hypothetical protein MAB_0877c |
| M. marinum M | MMAR_4654 | - | 3e-53 | 63.76% (149) | hypothetical protein MMAR_4654 |
| M. avium 104 | MAV_1006 | - | 7e-60 | 67.79% (149) | hypothetical protein MAV_1006 |
| M. smegmatis MC2 155 | MSMEG_5690 | - | 6e-60 | 68.00% (150) | hypothetical protein MSMEG_5690 |
| M. thermoresistible (build 8) | TH_1375 | - | 5e-66 | 76.67% (150) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0272 | - | 7e-53 | 63.09% (149) | hypothetical protein MUL_0272 |
| M. vanbaalenii PYR-1 | Mvan_5038 | - | 4e-69 | 81.21% (149) | activator of Hsp90 ATPase 1 family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1713|M.gilvum_PYR-GCK MA-APILQ--AEIDINAPVSKVWELVADLKKMSQWSPQCRVMKPLGTLRP
Mvan_5038|M.vanbaalenii_PYR-1 MA-APVLQ--AEIDINAPVSKVWELVSDLRKMPQWSPQCRLMKPIGQLRP
TH_1375|M.thermoresistible__bu MA-APLLQ--AEIEINAPVSRVWELVSDLSRMPQWSPQCRRMRVLGQLRP
MSMEG_5690|M.smegmatis_MC2_155 MA-APLLQ--AQIDIDAPVERVWSLISDLRRMPEWSPQCRLMKTIGPLRP
MMAR_4654|M.marinum_M MA-SPLLQ--THIDIDAPPSKVWALISDLRRMPEWSPQCRWMHQFGPLRQ
MUL_0272|M.ulcerans_Agy99 MA-SPLLQ--THIDIDAPPSKVWALISDLRRMPEWSPQCRWMHQFGPLRQ
MAV_1006|M.avium_104 MV-APLLR--AQIDIDAPVATVWELVSDLRRMPQWSPQCRWMKPLGPVRQ
MAB_0877c|M.abscessus_ATCC_199 MPNASLLE--AAVEIDAPVEKVWGLISDLDNMPRWSPQTRKMFVRGPVQA
Mb1915c|M.bovis_AF2122/97 MCLDQVMEGSATVHMAAPPDKIWTLIADVRNTGRFSPETFEAEWLDGATG
Rv1883c|M.tuberculosis_H37Rv MCLDQVMEGSATVHMAAPPDKIWTLIADVRNTGRFSPETFEAEWLDGATG
MLBr_02031|M.leprae_Br4923 ------MEGSVTVHMAAPADKVWNLIADVRNTGRFSPETFEAEWLDDVTG
:. . :.: ** :* *::*: . .:**: .
Mflv_1713|M.gilvum_PYR-GCK GTRTINLN---RRG--PLFWPTTCRITEFVPEQKLGFRVNENN---TVWT
Mvan_5038|M.vanbaalenii_PYR-1 GARTINFN---RRG--FLFWPTSCRITEVIPEKKLAFQVAENH---TVWS
TH_1375|M.thermoresistible__bu GARTINLN---RRG--LMVWPTTCTITEVIPEKKLAFRVNENN---TVWS
MSMEG_5690|M.smegmatis_MC2_155 GALTVNLN---RRN--FMFWPTTCHILEVIPQQKLAFRVDLNK---TVWA
MMAR_4654|M.marinum_M GTRTLNLN---RRN--RLFWPTTSRIVEVIPEQKLAFRVDTNR---TIWS
MUL_0272|M.ulcerans_Agy99 GTRTLNFN---RRN--RLFWPTSSRIVEVIPEQKLAFRVDTNR---TIWS
MAV_1006|M.avium_104 GTRTINLN---RRN--RLFWPTTCTVVEIIPDRKLAFRVDTNN---TIWS
MAB_0877c|M.abscessus_ATCC_199 GTNVINYN---RKG--WKVWPTRAVLTAVEPNKRLAWHVKDNL---SEWS
Mb1915c|M.bovis_AF2122/97 PALGARFRGHVRRNGIGPVYWTVCEVTACEPGREFGFAVLLGDRPVNNWH
Rv1883c|M.tuberculosis_H37Rv PALGARFRGHVRRNGIGPVYWTVCE-----PGREFGFAVLLGDRPVNNWH
MLBr_02031|M.leprae_Br4923 PALNAKFRGHVRRNEIGPVYWTTCKVTACEPGREFGFTVLLGNKPVNNWH
: . . *:. .: * . * :.:.: * . . *
Mflv_1713|M.gilvum_PYR-GCK YELEPTEAG-TRLVETRHAENGTSAVSNFLVGKFMGGVPSFEQELIEGMN
Mvan_5038|M.vanbaalenii_PYR-1 YELEPTEAG-TRLTETRHAENGTTAVSAFLVDKFMGGTTTFEQELIEGMN
TH_1375|M.thermoresistible__bu YELEPTESGGTRLIESRHAENGVKPISNFLVNRFMGGVPNFEQELLDGMN
MSMEG_5690|M.smegmatis_MC2_155 YELEPTETG-TRVTESRHAENGTTAVSNAVITAFFGGVPNFEGELIEGMN
MMAR_4654|M.marinum_M YELAPHGAG-TRLTESRHAENGVSAFSSMSVNALLGGNTNFERELVEGMN
MUL_0272|M.ulcerans_Agy99 YELAPHGAG-TRLTESRHAENGVSAFSSMSVNALLGGNTNFERELVEGMN
MAV_1006|M.avium_104 YELEPTDTG-TRLIESRHAENGVTAFSNLSVKAFLGGTDNFERELLDGMN
MAB_0877c|M.abscessus_ATCC_199 YDLEPTAAGGTRVTERRVLGDKRSAVSTNLQNLMFGGTEVFDQVLLEGMR
Mb1915c|M.bovis_AF2122/97 YRLTPTADG-TEVTESFRLP---PSVLTTVYYRVFGGWLRQRRNIRD-MT
Rv1883c|M.tuberculosis_H37Rv YRLTPTADG-TEVTESFRLP---PSVLTTVYYRVFGGWLRQRRNIRD-MT
MLBr_02031|M.leprae_Br4923 YRLVTSGDG-TYVTESFRFN---RSPLLTVYW-LLGGFLRKRRNIRD-MT
* * . * * : * . .:** : : *
Mflv_1713|M.gilvum_PYR-GCK ASLQRIKAAAEK----
Mvan_5038|M.vanbaalenii_PYR-1 ASLTRIKSAAES----
TH_1375|M.thermoresistible__bu ASLARIKAAAES----
MSMEG_5690|M.smegmatis_MC2_155 QSLARIKAAAER----
MMAR_4654|M.marinum_M TSLARIKAAAEAG---
MUL_0272|M.ulcerans_Agy99 TSLARIKAAAEAG---
MAV_1006|M.avium_104 ASLARIKAAAENTDRR
MAB_0877c|M.abscessus_ATCC_199 TSLSKIKAAAEGV---
Mb1915c|M.bovis_AF2122/97 KTLQRIKDLVEAG---
Rv1883c|M.tuberculosis_H37Rv KTLQRIKDLVEAG---
MLBr_02031|M.leprae_Br4923 KTLRRIKDVVEAE---
:* :** .*