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SSSWIAVLAVLIGAVGVAFMVSRMISSRSEMTPTDDEARAVDTAGLGLSTTGPTVLHFSASWCGPCAGVR RVVDRVCEDLPAVEHVEIDMDANPEAARRLSVLSLPTTIIFDADGRPRYRTSRVPTAADLRSALEPLLA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1648 | - | - | 100% (140) | thioredoxin domain-containing protein |
| M. gilvum PYR-GCK | Mflv_0838 | - | 4e-10 | 37.23% (94) | thioredoxin |
| M. gilvum PYR-GCK | Mflv_0987 | - | 3e-07 | 37.33% (75) | thioredoxin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0839c | thiX | 5e-35 | 57.25% (131) | thioredoxin ThiX |
| M. tuberculosis H37Rv | Rv0816c | thiX | 6e-35 | 57.25% (131) | thioredoxin ThiX |
| M. leprae Br4923 | MLBr_02196 | thiX | 4e-38 | 56.20% (137) | thiredoxin |
| M. abscessus ATCC 19977 | MAB_0742c | - | 9e-34 | 52.78% (144) | thioredoxin ThiX |
| M. marinum M | MMAR_3647 | thiX | 3e-43 | 63.16% (133) | thioredoxin ThiX |
| M. avium 104 | MAV_0758 | - | 1e-39 | 58.52% (135) | thioredoxin |
| M. smegmatis MC2 155 | MSMEG_5786 | - | 6e-46 | 61.69% (154) | thiredoxin |
| M. thermoresistible (build 8) | TH_2412 | trxC | 4e-10 | 36.96% (92) | THIOREDOXIN TRXC (TRX) (MPT46) |
| M. ulcerans Agy99 | MUL_1463 | thiX | 3e-43 | 63.16% (133) | thioredoxin ThiX |
| M. vanbaalenii PYR-1 | Mvan_5099 | - | 3e-52 | 70.63% (143) | thioredoxin domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3647|M.marinum_M MSTTL--IAAS----------AIVAALTGASAIGLTVNRRAGVLRET---
MUL_1463|M.ulcerans_Agy99 MSTTL--IAAS----------AIVAALTGASAIGLTVNRRAGVLRET---
MAB_0742c|M.abscessus_ATCC_199 MTSDLSALHASGSSPLVTAVIAIAVALLASSLIAVAIKSRSGKLRE----
Mflv_1648|M.gilvum_PYR-GCK MSSSWIAVLAV-----------LIGAVGVAFMVSRMISSRSEMTPT----
Mvan_5099|M.vanbaalenii_PYR-1 MSSSWIAVIAV-----------LIAAFGLAFVIGRLLTLRSGLIKG----
MSMEG_5786|M.smegmatis_MC2_155 MSSSMAAAVAV-----------LIAALVLAYVIGRVLTRRSGRVRQTGPG
Mb0839c|M.bovis_AF2122/97 ----MTTMIVA-----------SVATGALATIARWLLTRRSVILREVG--
Rv0816c|M.tuberculosis_H37Rv ----MTTMIVA-----------SVATGALATIARWLLTRRSVILREVG--
MLBr_02196|M.leprae_Br4923 ----MMTAIVA-----------TITVGMLTAFTGRWLTRHSGNVHEIC--
MAV_0758|M.avium_104 -----MTTLVV-----------IFAVLAAATLAGWLLTRRSGRIREID--
TH_2412|M.thermoresistible__bu -------------------------------MSGTVTVTDSTFKTDV---
:
MMAR_3647|M.marinum_M --GPSTDRAHQDTSD------LGLSETGPTVMHFSANWCGPCAAVRRVVD
MUL_1463|M.ulcerans_Agy99 --GPSTDRAHQDTSD------LGLSETGPTVMHFSANWCGPCAAVRRVVD
MAB_0742c|M.abscessus_ATCC_199 --GPGGTDDVQAPPG------IELSATGPTIVHFSAVWCGPCAAVRRVVD
Mflv_1648|M.gilvum_PYR-GCK ---DDEARAVDTA-------GLGLSTTGPTVLHFSASWCGPCAGVRRVVD
Mvan_5099|M.vanbaalenii_PYR-1 ---AAEWPALDDSDVD----ALGLSRTGPTVLHFSAVWCGPCAGVRRVVD
MSMEG_5786|M.smegmatis_MC2_155 SAVGAETDAVAQAEAERNLTDLGLSRTGPTILHFSAEWCGPCAGVRRVVD
Mb0839c|M.bovis_AF2122/97 ---PETTPAAPARTAE-----LGLSGAGPTVVHFRAPGCAPCDRVRRGVG
Rv0816c|M.tuberculosis_H37Rv ---PETTPAAPARTAE-----LGLSGAGPTVVHFRAPGCAPCDRVRRGVG
MLBr_02196|M.leprae_Br4923 ---SGPGQGTGTDTAD-----LGLSRTGPTIVHFSAPWCGPCDRVRRVVY
MAV_0758|M.avium_104 ---AGPQRDTGDDVAA-----LGLSRDGPTVVHFSAPWCGPCDRVRRVVD
TH_2412|M.thermoresistible__bu -----------------------LDSDTPVLVDFWADWCGPCKMVAPVLE
*. *.::.* * *.** * :
MMAR_3647|M.marinum_M QVCEELP-DVAHVEVDIDANPVAAKRLSVLSLPTTFIFDTDGRQRYRTAG
MUL_1463|M.ulcerans_Agy99 QVCEELP-DVAHVEVDSDANPVAAKRLSVLSLPTTFIFDTDGRQRYRTAG
MAB_0742c|M.abscessus_ATCC_199 QVSADHP-EVAHIEVDIDANPDAARVLSVLSLPTTFIFDATGRQAYRVSG
Mflv_1648|M.gilvum_PYR-GCK RVCEDLP-AVEHVEIDMDANPEAARRLSVLSLPTTIIFDADGRPRYRTSR
Mvan_5099|M.vanbaalenii_PYR-1 QVCAELP-EVTHVEIDLDADPESARKLSVLSLPTTFIFDADGRQRYRTSG
MSMEG_5786|M.smegmatis_MC2_155 QVCAELP-AIAHVEIDMDANPQAARRLSVLSLPTTFIFDARGHQRYRTSG
Mb0839c|M.bovis_AF2122/97 DVCADLG-DVAHIEVDLDSNPQAARRFSVLSLPTTLIFDVDGRQRYRTSG
Rv0816c|M.tuberculosis_H37Rv DVCADLG-DVAHIEVDLDSNPQAARRFSVLSLPTTLIFDVDGRQRYRTSG
MLBr_02196|M.leprae_Br4923 QVCKDLP-DVAHIEIDLDTNPAAVRRFSVLSLPTTLIFDTDGQQRYRTSG
MAV_0758|M.avium_104 QVCADLG-GVAHVEIDLDAHPDTARRYAVLSLPTTLIFDADGRQRYRSSG
TH_2412|M.thermoresistible__bu EIANEKSGTLKVAKLDVDANPEAARDFQVVSIPTMILFKG-GTPVKRIVG
:. : : ::* *:.* :.: *:*:** ::*. * *
MMAR_3647|M.marinum_M VPKVADLRATLIPLLT--
MUL_1463|M.ulcerans_Agy99 VPKVADLRATLIPLLT--
MAB_0742c|M.abscessus_ATCC_199 VPKATDLRTALQGMTQPG
Mflv_1648|M.gilvum_PYR-GCK VPTAADLRSALEPLLA--
Mvan_5099|M.vanbaalenii_PYR-1 VPTAADLRSALQPLLA--
MSMEG_5786|M.smegmatis_MC2_155 VPRAADLRTAVEPLLA--
Mb0839c|M.bovis_AF2122/97 VPKAADLRSALKPLLA--
Rv0816c|M.tuberculosis_H37Rv VPKAADLRSALKPLLA--
MLBr_02196|M.leprae_Br4923 VPKAFDLLSTLEPLLA--
MAV_0758|M.avium_104 VPGAADLRSALKPLLA--
TH_2412|M.thermoresistible__bu AKGKAALLREIEDAL---
. * :