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MSAPLVDRVRERLAQETAPLRPSVVAAAIRAESGGVLGDAEVLRSLRELQTELTGAGALDPLLSAPGTTD VLVTAPDAVWIDDGRGLRRTSVRFADEAAVRRLAQRLALTAGRRLDEAQPWVDGHLLAPGPGGQLTVRLH AVLPPVAAAGTCLSLRVLRPANQNLDALTSAGTLTPEAAGLLRDILAARLAFVVSGGTGAGKTTLLAALL AAVPHTERIVCVEDAAELAPDHPHLVKLVARGANVEGAGEVTVRDLVRQALRMRPDRIVIGEVRGPEVVD LLSALNTGHDGGAGTVHANSPAEVPARFEALAALGGLDRAALHSQLAAAIQVVLHVARDRAGRRHLAEIG LLYRAGGGSVDVVRCWHRDDGFGRGAGELRALLRARDGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1384 | - | - | 100% (389) | type II secretion system protein E |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3683c | - | 1e-144 | 75.78% (351) | hypothetical protein Mb3683c |
| M. tuberculosis H37Rv | Rv3659c | - | 1e-144 | 75.78% (351) | hypothetical protein Rv3659c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0433 | - | 1e-133 | 73.64% (330) | Type II secretion system protein E |
| M. marinum M | MMAR_5147 | - | 1e-160 | 75.97% (387) | hypothetical protein MMAR_5147 |
| M. avium 104 | MAV_0471 | - | 1e-144 | 79.94% (334) | Type II/IV secretion system protein |
| M. smegmatis MC2 155 | MSMEG_6169 | - | 1e-155 | 75.47% (375) | type II/IV secretion system protein |
| M. thermoresistible (build 8) | TH_2272 | trbB | 1e-131 | 72.54% (346) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4232 | - | 1e-156 | 74.42% (387) | hypothetical protein MUL_4232 |
| M. vanbaalenii PYR-1 | Mvan_5421 | - | 1e-161 | 87.39% (333) | type II secretion system protein E |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1384|M.gilvum_PYR-GCK MSAPLVDRVRERLAQE----TAPLRPSVVAAAIRAESGGVLGDAEVLRSL
Mvan_5421|M.vanbaalenii_PYR-1 MSAPLIDRVRERLAMQ----SSPLRPSVVAAAIRAESGGVLGDAEVLTNL
MAB_0433|M.abscessus_ATCC_1997 MTGSLIDRVRERLAAD----NVALRPTAVAAAIRAESGGVLGDSDVLHNI
TH_2272|M.thermoresistible__bu MTSSLIDRVRARLAAGPLTAGASLRPDVVAAAIRAESGGVVGDTEVLATL
MAV_0471|M.avium_104 MSSSLIDRVRERLAGETVPLGAPLPASVVAAAIRAESGGMLGDTEVLANL
Mb3683c|M.bovis_AF2122/97 ---------------------------------------MLGDTEVLANL
Rv3659c|M.tuberculosis_H37Rv ---------------------------------------MLGDTEVLANL
MMAR_5147|M.marinum_M MNGPLIERVRERLTTE----PGPLRPSVVAAAIRAESGGMLGDTEVLANL
MUL_4232|M.ulcerans_Agy99 MNGPLIERVSERLTTE----PGPPRPSVVAAAIRAESGGMLGDTEVLANL
MSMEG_6169|M.smegmatis_MC2_155 MSPSLIDRVRERLVAE----TAPLSPDVVAAAIRAESGGLLGDTEVLSNL
::**::** .:
Mflv_1384|M.gilvum_PYR-GCK RELQTELTGAGALDPLLSAPGTTDVLVTAPDAVWIDDGRGLRRTSVRFAD
Mvan_5421|M.vanbaalenii_PYR-1 RELQTELIGAGILDPLLSGPGVTDVLVTAPDAVWVDDGNGLRRTSVRFAD
MAB_0433|M.abscessus_ATCC_1997 KELQSELSGAGILEPLLCADDTTDVLVTAPDRVWVDDGHGLRLTAVRFTD
TH_2272|M.thermoresistible__bu RELQTELIGAGVLEPLLRADGVTDVLVTGPDAVWVDDGGGLRRTAVRFPD
MAV_0471|M.avium_104 RTLQTELTGAGILEPLLCADGTTDVLVTAPDAVWVDDGNGLRRSEIRFPD
Mb3683c|M.bovis_AF2122/97 RVLQTELTGAGILEPLLSADGTTDVLVTAPDSVWVDDGNGLRRSQIRFAD
Rv3659c|M.tuberculosis_H37Rv RVLQTELTGAGILEPLLSADGTTDVLVTAPDSVWVDDGNGLRRSQIRFAD
MMAR_5147|M.marinum_M RVLQTELTGAGILEPLLCADGTTDVLVTAPDAVWVDDGNGLRRSEVRFAD
MUL_4232|M.ulcerans_Agy99 RVLQTELTGAGILEPLLCADGTTDVLVIAPDAVWVDDGNGLRRSEVRFAD
MSMEG_6169|M.smegmatis_MC2_155 RALDTELTGAGVLEPLLRADGTTDVLVTAPDAVWVDAGHGLRRTDIRFPD
: *::** *** *:*** . ..***** .** **:* * *** : :**.*
Mflv_1384|M.gilvum_PYR-GCK EAAVRRLAQRLALTAGRRLDEAQPWVDGHLLAPG---PGGQLTVRLHAVL
Mvan_5421|M.vanbaalenii_PYR-1 DAAVRRLAQRLALTAGRRLDEAQPWVDGNLSGFGAGQPGGPLSVRLHAVL
MAB_0433|M.abscessus_ATCC_1997 EAAVRRLAQRLALAVGRRLDDAQPFVDGQLLDVG----PPRSVVRLHAVL
TH_2272|M.thermoresistible__bu EQAVRRLAQRLAVAAGRRLDEAQPWVDGQLTGLG----EGMFTVRLHAVL
MAV_0471|M.avium_104 EAAVRRLAQRLALAAGRRLDDAQPWVDGELTGIG----AGGFAVRLHAVL
Mb3683c|M.bovis_AF2122/97 ESAVRRLAQRLALAAGRRLDDAQPWVDGQLTGIG----VGGFAVRLHAVL
Rv3659c|M.tuberculosis_H37Rv ESAVRRLAQRLALAAGRRLDDAQPWVDGQLTGIG----VGGFAVRLHAVL
MMAR_5147|M.marinum_M EAAVRRLAQRLALAAGRRLDDAQPWVDGHLGGIG----TGGLTVRLHAVL
MUL_4232|M.ulcerans_Agy99 EAAVRRLAQRLALAAGRRLDDAQPWVDGHLGGIG----TGGLTVRLHAVL
MSMEG_6169|M.smegmatis_MC2_155 EAAVRRLAQRLALLAGRRLDEAQPWVDGHLGGMG----P--FTVRLHAVL
: **********: .*****:***:***.* * *******
Mflv_1384|M.gilvum_PYR-GCK PPVAAAGTCLSLRVLRPANQNLDALTSAGTLTPEAAGLLRDILAARLAFV
Mvan_5421|M.vanbaalenii_PYR-1 PPVAAGGTCLSLRVLRPANQDLDALIGAGAIEPDAAGILRDVISARLAFV
MAB_0433|M.abscessus_ATCC_1997 APIAAAGTCISLRVLRPMAKGLDQLIADGTVPEDAGRLLRGMLAARLAFL
TH_2272|M.thermoresistible__bu PPIAAAGTVLSLRVLRPATQDLGALIRAGTIAPPAADLLAGVLRARLAFL
MAV_0471|M.avium_104 PPVAAAGTCLSLRVLRPASQDLAALSAAGAIEPAAAALVADIIAARLAFL
Mb3683c|M.bovis_AF2122/97 PPVATQGTCLSLRVLRPATQDLAALAAAGAIDPAAAALVADIVTARLAFL
Rv3659c|M.tuberculosis_H37Rv PPVATQGTCLSLRVLRPATQDLAALAAAGAIDPAAAALVADIVTARLAFL
MMAR_5147|M.marinum_M PPVAAAGTCLSLRVLRPTTVDLAALIASGAIAEQAAELVGEILAARLAFL
MUL_4232|M.ulcerans_Agy99 PPVAAAGTCLSLRVLRPTTVDLAALIAAGAIAEQAAELVGEILAARLAFL
MSMEG_6169|M.smegmatis_MC2_155 PPIAAAGTCLSLRVLRPATQNLDSLARSGAIAPAAVDLLRRVIDARLAFL
.*:*: ** :******* .* * *:: * :: :: *****:
Mflv_1384|M.gilvum_PYR-GCK VSGGTGAGKTTLLAALLAAVPHTERIVCVEDAAELAPDHPHLVKLVARGA
Mvan_5421|M.vanbaalenii_PYR-1 VSGGTGAGKTTLLAALLAAVPEDERIVCVEDAAELAPDHPHLVKLVARCA
MAB_0433|M.abscessus_ATCC_1997 VTGGTGAGKTTLLSALLGAVDPTERIICAEDAAELAPRHPHVVSLAARAV
TH_2272|M.thermoresistible__bu VSGGTGAGKTTLLSALLGAISDAERIVCVEDAPENR---------AARAA
MAV_0471|M.avium_104 VSGGTGAGKTTLLAAILGAVPPDERIVCVEDAAELAPPHPHLVKLVARCA
Mb3683c|M.bovis_AF2122/97 VCGGTGAGKTTLLAAMLGAVSPDERIVCVEDAAELAPRHPHLVKLVARRA
Rv3659c|M.tuberculosis_H37Rv VCGGTGAGKTTLLAAMLGAVSPDERIVCVEDAAELAPRHPHLVKLVARRA
MMAR_5147|M.marinum_M VCGGTGAGKTTLLAAMLGAVAGSERIVCVEDAAELAPRHPHLVKLVARCA
MUL_4232|M.ulcerans_Agy99 VCGGTGPGKTTLLAAMLGAVAGSERIVCVEDAAELAPRHPHLVKLVARCA
MSMEG_6169|M.smegmatis_MC2_155 ISGGTGAGKTTLLSALLGTVPGHERIVCVEDAAELAPQHPHVVRLVARNA
: ****.******:*:*.:: ***:*.***.* .** .
Mflv_1384|M.gilvum_PYR-GCK NVEGAGEVTVRDLVRQALRMRPDRIVIGEVRGPEVVDLLSALNTGHDGGA
Mvan_5421|M.vanbaalenii_PYR-1 NVEGAGEVTVRDLVRQALRMRPDRIVIGEVRGAEVVDLLTALNTGHDGGA
MAB_0433|M.abscessus_ATCC_1997 NIEGVGEVTLRQLVRQALRMRPDRIVVGEVRGAEVVELLTALNTGHDGGA
TH_2272|M.thermoresistible__bu NVEGVGEVTMRDLVRQALRMRPDRLVVGEVRGAEVVDLLAALNTGHDGGA
MAV_0471|M.avium_104 NVEGVGEVPVRQLVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHDGGA
Mb3683c|M.bovis_AF2122/97 NVEGIGEVTVRQLVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHEGGA
Rv3659c|M.tuberculosis_H37Rv NVEGIGEVTVRQLVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHEGGA
MMAR_5147|M.marinum_M NVEGAGEVTLRQLVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHEGGA
MUL_4232|M.ulcerans_Agy99 NVEGAGKVTLRQLVRQALRVRPDRIVVGEVRGAGVVDLLAALNTGHEGGA
MSMEG_6169|M.smegmatis_MC2_155 NVEGVGEITVRDLVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHDGGA
*:** *::.:*:*******:****:*:*****. **:**:******:***
Mflv_1384|M.gilvum_PYR-GCK GTVHANSPAEVPARFEALAALGGLDRAALHSQLAAAIQVVLHVARDRAGR
Mvan_5421|M.vanbaalenii_PYR-1 GTVHANNPAEVPARFEALAALGGLDRAALHSQLAAAILSVTGCGVCRTVT
MAB_0433|M.abscessus_ATCC_1997 GTVHANAPAEVPARLEALGALGGLDRAALHSQFAAAILSVTDARVCMTVT
TH_2272|M.thermoresistible__bu GTVHANSPADVPARLEALAALGGLDRAALHSQLAAAVLSVTSIGMCKTGT
MAV_0471|M.avium_104 GTVHANNPGEVPARLEALGALGGLDRAALHSQLAAAVLSVGRSGVWLTVS
Mb3683c|M.bovis_AF2122/97 GTVHANNPGEVPARMEALGALGGLDRAALHSQLAAAVQVLLHVARDRAGR
Rv3659c|M.tuberculosis_H37Rv GTVHANNPGEVPARMEALGALGGLDRAALHSQLAAAVQVLLHVARDRAGR
MMAR_5147|M.marinum_M GTVHANSPGEVPARLEALGALGGLDRAALHSQLAAAVQVLLHVTRDQGGR
MUL_4232|M.ulcerans_Agy99 GTVHANSPGEVPARLEALGALGGLDRAALHSQLAAAVQVLLHVTRDQGGR
MSMEG_6169|M.smegmatis_MC2_155 GTVHANSPAEVPARLEALGALGGLDRYALSSQAAAAVQVLLHVDRGLAGR
****** *.:****:***.******* ** ** ***: :
Mflv_1384|M.gilvum_PYR-GCK RHLAEIGLLYRAGGGSVDVVRCWHRDDGFGRGAGELR-----ALLRARDG
Mvan_5421|M.vanbaalenii_PYR-1 HVGFRWGFLVGDTVICNGVTDVGSRWVLLCCGGGAVRRVRWRGLVRGFCS
MAB_0433|M.abscessus_ATCC_1997 DVTYRV----GKDRCSHGYL------------------------------
TH_2272|M.thermoresistible__bu HVDLEC----RASRRCQSYL------------------------------
MAV_0471|M.avium_104 DGEIRP----CACRREQPYL------------------------------
Mb3683c|M.bovis_AF2122/97 RRLAEIAVLRQAEG-RVQAVTVWHADRGMS-DDAAALHDLLRSRASA---
Rv3659c|M.tuberculosis_H37Rv RRLAEIAVLRQAEG-RVQAVTVWHADRGMS-DDAAALHDLLRSRASA---
MMAR_5147|M.marinum_M RRLSEIAVLHRAEDGLVAALTAWHADRGMAQDGGAVLRGLLSGRGTP---
MUL_4232|M.ulcerans_Agy99 RRLSEIAVLHRAEDGLVAALTAWHADRGMAQDGGAVLRGLLSGRGTP---
MSMEG_6169|M.smegmatis_MC2_155 RRLSEIAVLRRHES-GLEVATAWHADAGLG-CGMELLAEKFTQRGMR---
.
Mflv_1384|M.gilvum_PYR-GCK S-
Mvan_5421|M.vanbaalenii_PYR-1 RL
MAB_0433|M.abscessus_ATCC_1997 --
TH_2272|M.thermoresistible__bu --
MAV_0471|M.avium_104 --
Mb3683c|M.bovis_AF2122/97 --
Rv3659c|M.tuberculosis_H37Rv --
MMAR_5147|M.marinum_M --
MUL_4232|M.ulcerans_Agy99 --
MSMEG_6169|M.smegmatis_MC2_155 --