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VTSSRDPLAPLTELPGVAAAADEAREALGRAHRHRANLRGWPQNAAEASLRAARASSVLDGGALQFPPDG TEPVLAGAIRVAEALEGGEGTLVGVWRRAPLQAIARLHSLAAADLVDDDALGRPREGAGRRLELLAALAT GRTRVPASILAAVAHGELLTLEPFGSADGVVARGVSRLITIASGLDPHGLGVPEVHWMRRSNDYRAAARG FASGTPDGLTAWLLLSCEGLHAGAREALSIAQAPSAQG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1381 | - | - | 100% (248) | hypothetical protein Mflv_1381 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3686c | - | 2e-88 | 67.73% (251) | hypothetical protein Mb3686c |
| M. tuberculosis H37Rv | Rv3662c | - | 6e-89 | 68.13% (251) | hypothetical protein Rv3662c |
| M. leprae Br4923 | MLBr_02289 | - | 1e-89 | 68.67% (249) | hypothetical protein MLBr_02289 |
| M. abscessus ATCC 19977 | MAB_0430 | - | 5e-81 | 63.33% (240) | hypothetical protein MAB_0430 |
| M. marinum M | MMAR_5150 | - | 5e-87 | 67.07% (249) | hypothetical protein MMAR_5150 |
| M. avium 104 | MAV_0468 | - | 8e-93 | 72.08% (240) | hypothetical protein MAV_0468 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_0712 | - | 2e-50 | 72.39% (134) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4236 | - | 3e-87 | 67.07% (249) | hypothetical protein MUL_4236 |
| M. vanbaalenii PYR-1 | Mvan_5424 | - | 1e-111 | 84.43% (244) | hypothetical protein Mvan_5424 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1381|M.gilvum_PYR-GCK ----------------------------MTSSRDPLAPLTELPGVA-AAA
Mvan_5424|M.vanbaalenii_PYR-1 --------------MPPALRPSGRLPCPGVTPDDPLAPLTTLPGVA-EAG
MMAR_5150|M.marinum_M ------------------------------MTADPLAALMELPGVG-DAS
MUL_4236|M.ulcerans_Agy99 ------------------------------MTADPLAALMELPGVG-DAS
MLBr_02289|M.leprae_Br4923 ------------------------------MTADLLAPLMELPGVA-TAS
MAV_0468|M.avium_104 ---------------------------------------MELPGVA-EAS
Mb3686c|M.bovis_AF2122/97 ------------------------------MTVDPLAPLMELPGVA-AAS
Rv3662c|M.tuberculosis_H37Rv ------------------------------MTVDPLAPLMELPGVA-AAS
MAB_0430|M.abscessus_ATCC_1997 -------------------------------MTDPLAPLASLPGVP-EAA
TH_0712|M.thermoresistible__bu MSAPSAVERVHAAYAAIERVDRPEIWITLRPLADALADAVRVDAAARTGA
: .. ..
Mflv_1381|M.gilvum_PYR-GCK DEAREALGRAHRHRANLRGWPQNA-----------AEA------------
Mvan_5424|M.vanbaalenii_PYR-1 EEAREALGRAHRHRANLRGWPKSA-----------AEA------------
MMAR_5150|M.marinum_M DRAREALGQAHRHRANLRGWPVTA-----------AEA------------
MUL_4236|M.ulcerans_Agy99 DRAREALGQAHRHRANLRGWPVTA-----------AEA------------
MLBr_02289|M.leprae_Br4923 DRARDALGRAHRHRANLRGWPVTA-----------AEA------------
MAV_0468|M.avium_104 DRARDALGRAHRHRANLRGWPVTA-----------AEA------------
Mb3686c|M.bovis_AF2122/97 DRVRDALSRVHRHRTNLRGWPVAA-----------AEA------------
Rv3662c|M.tuberculosis_H37Rv DRVRDALSRVHRHRANLRGWPVAA-----------AEA------------
MAB_0430|M.abscessus_ATCC_1997 EAARDALTKVHRHRANLRGWPVTA-----------AEA------------
TH_0712|M.thermoresistible__bu ELPLAGLVAAVKNNIDVAGIPTTAGCPTFATCAATADAPAVARLRTAGAV
: .* . ::. :: * * * *:*
Mflv_1381|M.gilvum_PYR-GCK ----------------------SLRAARASSVLDGGALQFP-PDG-----
Mvan_5424|M.vanbaalenii_PYR-1 ----------------------SLRAARASSVLDGGPLQFANVDD-----
MMAR_5150|M.marinum_M ----------------------ALRGARASSVLDGGPTRLEDLVDASAGD
MUL_4236|M.ulcerans_Agy99 ----------------------ALRGARASSVLDGGPTRLEDLVDPSAGD
MLBr_02289|M.leprae_Br4923 ----------------------ALRAARASSVLDGGPVRLDHLPGASPQA
MAV_0468|M.avium_104 ----------------------ALRAARASSVLDGGPVRLEDLA----EA
Mb3686c|M.bovis_AF2122/97 ----------------------SLRAARASSVLDGGPARLHDAGAPTSGK
Rv3662c|M.tuberculosis_H37Rv ----------------------SLRAARASSVLDGGPARLHDAGAPTSGK
MAB_0430|M.abscessus_ATCC_1997 ----------------------AVRAARSSSALDGGTMKLSADG------
TH_0712|M.thermoresistible__bu VIGATNLDQFATGLVGTRSPYGAVRDARRPDRISGGSSSGSAVAVALGLV
::* ** .. :.**.
Mflv_1381|M.gilvum_PYR-GCK ---TEPVLAGAIRVAEALE-------------------------------
Mvan_5424|M.vanbaalenii_PYR-1 ---RDPVLAGALRVAEALE-------------------------------
MMAR_5150|M.marinum_M PVVNDPVFGGALRVAQALE-------------------------------
MUL_4236|M.ulcerans_Agy99 PVVNDPVFGGALRVAQALE-------------------------------
MLBr_02289|M.leprae_Br4923 GGVSDPVFGGALRVAQALE-------------------------------
MAV_0468|M.avium_104 GQISDPVFAGALRVAQALE-------------------------------
Mb3686c|M.bovis_AF2122/97 PALSDPVFAGALRVGQALE-------------------------------
Rv3662c|M.tuberculosis_H37Rv PALSDPVFAGALRVGQALE-------------------------------
MAB_0430|M.abscessus_ATCC_1997 -AVEDPILAGALRVGQALD-------------------------------
TH_0712|M.thermoresistible__bu DVALGTDTAGSGRVPAALQGIVGIKPTIGVVPTDGVVPACRSYDCVTVFA
. .*: ** **:
Mflv_1381|M.gilvum_PYR-GCK ------GGE-GTLVG------------------------------VWRRA
Mvan_5424|M.vanbaalenii_PYR-1 ------GGE-GALVG------------------------------VWRRA
MMAR_5150|M.marinum_M ------GGA-GPLVG------------------------------VWQKA
MUL_4236|M.ulcerans_Agy99 ------GGA-GPLVG------------------------------VWQKA
MLBr_02289|M.leprae_Br4923 ------GGA-GPLVG------------------------------VWQRA
MAV_0468|M.avium_104 ------GGE-GPVVG------------------------------IWRRA
Mb3686c|M.bovis_AF2122/97 ------GGA-GPVVG------------------------------VWRRA
Rv3662c|M.tuberculosis_H37Rv ------GGA-GPVVG------------------------------VWRRA
MAB_0430|M.abscessus_ATCC_1997 ------GDALTQLAA------------------------------VWSRA
TH_0712|M.thermoresistible__bu RDLDTADAAMGVLAGGGRPFPPDAPLTVPPTTRVAVPGRLPGLSPAWRQA
. :.. * :*
Mflv_1381|M.gilvum_PYR-GCK PLQAIARLH-----------------------------------------
Mvan_5424|M.vanbaalenii_PYR-1 PLQAIARLH-----------------------------------------
MMAR_5150|M.marinum_M PLQALARLH-----------------------------------------
MUL_4236|M.ulcerans_Agy99 PLQALARLH-----------------------------------------
MLBr_02289|M.leprae_Br4923 PLQALARLH-----------------------------------------
MAV_0468|M.avium_104 PLQALARLH-----------------------------------------
Mb3686c|M.bovis_AF2122/97 PLQALARLH-----------------------------------------
Rv3662c|M.tuberculosis_H37Rv PLQALARLH-----------------------------------------
MAB_0430|M.abscessus_ATCC_1997 PLQALARLH-----------------------------------------
TH_0712|M.thermoresistible__bu FESACERLAGNGIELVEVDLTPFLQAATLLYDGGLVAERHAAVGTFVDEH
.* **
Mflv_1381|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5424|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_5150|M.marinum_M --------------------------------------------------
MUL_4236|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02289|M.leprae_Br4923 --------------------------------------------------
MAV_0468|M.avium_104 --------------------------------------------------
Mb3686c|M.bovis_AF2122/97 --------------------------------------------------
Rv3662c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0430|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0712|M.thermoresistible__bu LAAGDPALDPTVAQIISAAGAVPATTLLRDRARLAELTASALARLGDCAA
Mflv_1381|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5424|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_5150|M.marinum_M --------------------------------------------------
MUL_4236|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02289|M.leprae_Br4923 --------------------------------------------------
MAV_0468|M.avium_104 --------------------------------------------------
Mb3686c|M.bovis_AF2122/97 --------------------------------------------------
Rv3662c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0430|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0712|M.thermoresistible__bu LLIPTTTEHPSIAEVAADPVGVNSRLGTYTNFCNLMDLCAVAVPAGTTSD
Mflv_1381|M.gilvum_PYR-GCK ------------------------------------------------SL
Mvan_5424|M.vanbaalenii_PYR-1 ------------------------------------------------AL
MMAR_5150|M.marinum_M ------------------------------------------------ML
MUL_4236|M.ulcerans_Agy99 ------------------------------------------------ML
MLBr_02289|M.leprae_Br4923 ------------------------------------------------VL
MAV_0468|M.avium_104 ------------------------------------------------ML
Mb3686c|M.bovis_AF2122/97 ------------------------------------------------ML
Rv3662c|M.tuberculosis_H37Rv ------------------------------------------------ML
MAB_0430|M.abscessus_ATCC_1997 ------------------------------------------------VL
TH_0712|M.thermoresistible__bu GAQFGVTVLGRAGADALALDLARLVSAPVDGAAPPGVPAPPTPAVPWPXX
Mflv_1381|M.gilvum_PYR-GCK AAADLVDDDALGRPR--EGAGRRLELLAALATGRTRVPASILAAVAHGEL
Mvan_5424|M.vanbaalenii_PYR-1 AAADLADGDTLGRPRRDEGVGRRLELLADLVTGGTRVPAPVLAAVAHGEL
MMAR_5150|M.marinum_M AAADLAADGGLGRPRADAGIGPRLELLADLVTRPTRASAPVIAAVAHGEL
MUL_4236|M.ulcerans_Agy99 AAADLAADGGLGRPRADAGIGPRLELLADLVTRPTRASAPVIAAVAHGEL
MLBr_02289|M.leprae_Br4923 AAADQVGDEWLGRPRMDAEVGLRLGLLVDVVSGRTFAAAPVVAAVVHGEL
MAV_0468|M.avium_104 AAADQVDDERLGRPRADAGVGPRLELLADLVNGRTRVPAPVLAAVAHGEL
Mb3686c|M.bovis_AF2122/97 AAADQVDDDRLGRPRSDADVGPRLELLADVVTHPTLASAPVVAAVAHGEL
Rv3662c|M.tuberculosis_H37Rv AAADQVDDDRLGRPRSDADVGPRLELLADVVTHPTLASAPVVAAVAHGEL
MAB_0430|M.abscessus_ATCC_1997 AATGMADEDTLGRPRPGADTD-RLELLAQLISGGTSVPAPILAAVTHGEL
TH_0712|M.thermoresistible__bu XAADLTDDDHLGRPRGDTETGQRLELLAHLVTGGTRAPATVLAAVVHGEL
*:. . ***** . ** **. : . * ..*.::***.****
Mflv_1381|M.gilvum_PYR-GCK LTLEPFGSADGVVARGVSRLITIASGLDPHGLGVPEVHWMRRSNDYRAAA
Mvan_5424|M.vanbaalenii_PYR-1 LTLAPFGTADGVVARAVSRLITIASGLDPHGLGVPEVHWMRRSGDYRAAA
MMAR_5150|M.marinum_M LTLRPFGTADGVVARGVSRLVTIATGLDPHGLGVPEVSWMRQPVGYRDAA
MUL_4236|M.ulcerans_Agy99 LTLRPFGTADGVVARGVSRLVTIATGLDPHGLGVPEVSWMRQPVGYRDAA
MLBr_02289|M.leprae_Br4923 LTLQPFGSADGVVARAVSRLVTIATGLDPHGLGVPEVSWMRRAAVYRDAA
MAV_0468|M.avium_104 LTLRPFGSCDGVVARAVSRLVTIASGLDPHGLGVPEVSWMRQPAAYRDAA
Mb3686c|M.bovis_AF2122/97 LTLRPFGCADGVVARAVSRLVTIATGLDPHGLGVPEVIWMRQPAEYHDAA
Rv3662c|M.tuberculosis_H37Rv LTLRPFGCADGVVARAVSRLVTIATGLDPHGLGVPEVIWMRQPAEYHDAA
MAB_0430|M.abscessus_ATCC_1997 LALNPFGSADGVVARAASRLVTVSRGLDPHALGVPEVMWMRQSGRYRELS
TH_0712|M.thermoresistible__bu LALAPFGTADGVVARAASRLVTMASGLDPHGLGVPEVFWMTQQRDYRAAA
*:* *** .******..***:*:: *****.****** ** : *: :
Mflv_1381|M.gilvum_PYR-GCK RGFASGTPDGLTAWLLLSCEGLHAGAREALSIAQAPSAQG
Mvan_5424|M.vanbaalenii_PYR-1 RGFASGTPDGLAAWLVLSSEALHAGAREALSIAQGASS--
MMAR_5150|M.marinum_M DRFAEGTPAGLAAWLVLCCRAMEAGAQEALAIANSVPRS-
MUL_4236|M.ulcerans_Agy99 DRFAEGTPAGLAAWLVLCCRAMEAGAQEALAIANSVPRS-
MLBr_02289|M.leprae_Br4923 CGFAGGTPKGVAAWLVLCCRALHAGAQEALSIAESLPSR-
MAV_0468|M.avium_104 RGFADGTPEGVGAWLVLCCRAMRAGAQEALSIADSMSNR-
Mb3686c|M.bovis_AF2122/97 RRFAGGTPDGVAGWLLLCCGAMLDGAREALSIAESLSPG-
Rv3662c|M.tuberculosis_H37Rv RRFAGGTPDGVAGWLLLCCGAMLDGAREALSIAESLSPG-
MAB_0430|M.abscessus_ATCC_1997 SAFAQGTPEAITAWIVFCCQALTAGAAEATSIADTAAG--
TH_0712|M.thermoresistible__bu QGFASGTRDGLTTWLMLTARALHAGAREAISIAEAQAEAN
** ** .: *::: . .: ** ** :**: .