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VTTRETLAGELIRARDRTLRLVDFDDAELRRQYDPLMSPLVWDLAHIGQQEELWLLRGGDPQRPGLLSAE VDQLYDAFVHSRAARVDLPLLPPTDARNYCATVRGRALDTLEALPDGHPDEFAYALVISHENQHDETMLQ ALSLRSGAPLLDRGDPLPPGRSGVAGTSVLVTGGEFVLGVDAVTEPFSLDNERPAHTVDVPDFRIGRVPV TNAEWRQFLDDGGYAQRRWWSDAGWTHRQQAGLTRPLFWNADGTRTRFGHVEDIPGDEPVQHVTYYEAQA YAAWAGARLPTEIEWEKACAWDPATGARRRFPWGTAEPTADVANLGGGALRPAPVGAFPASASACGAEQM LGDVWEWTSSPLRPWPGFTPMIYRQYSEPFFDGTASGEYRVLRGGSWAVAAGILRPSFRNWDHPIRRQIF SGVRLAWDV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1316 | - | - | 100% (429) | hypothetical protein Mflv_1316 |
| M. gilvum PYR-GCK | Mflv_5038 | - | 2e-19 | 33.48% (221) | hypothetical protein Mflv_5038 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3729c | - | 0.0 | 76.05% (430) | hypothetical protein Mb3729c |
| M. tuberculosis H37Rv | Rv3703c | - | 0.0 | 76.05% (430) | hypothetical protein Rv3703c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0370 | - | 0.0 | 72.09% (430) | hypothetical protein MAB_0370 |
| M. marinum M | MMAR_5214 | - | 0.0 | 73.96% (434) | hypothetical protein MMAR_5214 |
| M. avium 104 | MAV_0400 | - | 0.0 | 75.12% (430) | hypothetical protein MAV_0400 |
| M. smegmatis MC2 155 | MSMEG_6249 | - | 0.0 | 81.22% (426) | hypothetical protein MSMEG_6249 |
| M. thermoresistible (build 8) | TH_0066 | - | 2e-26 | 84.75% (59) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4287 | - | 0.0 | 73.73% (434) | hypothetical protein MUL_4287 |
| M. vanbaalenii PYR-1 | Mvan_5485 | - | 0.0 | 84.58% (428) | hypothetical protein Mvan_5485 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1316|M.gilvum_PYR-GCK MTTRETLAGELIRARDRTLRLVDFDDAELRRQYDPLMSPLVWDLAHIGQQ
Mvan_5485|M.vanbaalenii_PYR-1 MTTREALACELTEARDRTLRLVAFDDAELRRQYDPLMSPLVWDLAHIGQQ
Mb3729c|M.bovis_AF2122/97 MTSPEQLACHLARARARTLRLVDFDDAELCCQYDPLMSPLVWDLAHIGQQ
Rv3703c|M.tuberculosis_H37Rv MTSPEQLACHLARARARTLRLVDFDDAELCCQYDPLMSPLVWDLAHIGQQ
MAV_0400|M.avium_104 MTSPEAIADQLARTRARTLRLVDFDDDELRRQYDPLMSPLVWDLAHIGQQ
MMAR_5214|M.marinum_M MTSRERLAEDLDRVRTQTLRLVDFDDAELRRQYDPLMSPLVWDLAHIGQQ
MUL_4287|M.ulcerans_Agy99 MTSRERLAEDLDRVRTQTLRLVDFDDAELRRQYDPLMSPLVWDLAHIGQQ
MAB_0370|M.abscessus_ATCC_1997 -MSRDELARDLEAARMRTLTITDHDDAELHRQYDPLMSPLVWDLAHIGQQ
MSMEG_6249|M.smegmatis_MC2_155 MIARETLADELALARERTLRLVEFDDAELHRQYNPLMSPLVWDLAHIGQQ
TH_0066|M.thermoresistible__bu --------------------------------------------------
Mflv_1316|M.gilvum_PYR-GCK EELWLLRGGDPQRPGLLSAEVDQLYDAFVHSRAARVDLPLLPPTDARNYC
Mvan_5485|M.vanbaalenii_PYR-1 EELWLLRGGNPDRPGLLPPQVDQLYDAFVHSRASRADLPLLPPTDARNYC
Mb3729c|M.bovis_AF2122/97 EELWLLRGGDPGQPGLLPPAVEGLYDAFEHSRASRVELPLLSPARARSYC
Rv3703c|M.tuberculosis_H37Rv EELWLLRGGDPGQPGLLPPAVEGLYDAFEHSRASRVELPLLSPARARSYC
MAV_0400|M.avium_104 EELWLLRGGDPARPGMLPPAVEGLYDAFVHSRASRVDLPLLSPEQARAYC
MMAR_5214|M.marinum_M EELWLLREGDPDRPGMLPRAVEGLYDAFVHNRASRVELPLLSPAQAHSYC
MUL_4287|M.ulcerans_Agy99 EELWLLREGDPDRPGMLPRAVEGLYDAFVHNRASRVELPLLSPAQAHSYC
MAB_0370|M.abscessus_ATCC_1997 EELWLLRGGDPRRPGMLPGEIESLYDAFRHTRASRVQLPLLSPAQARAFC
MSMEG_6249|M.smegmatis_MC2_155 EELWLLRDGNPDRPGMLAPEVDRLYDAFEHSRASRVNLPLLPPSDARAYC
TH_0066|M.thermoresistible__bu --------------------------------------------------
Mflv_1316|M.gilvum_PYR-GCK ATVRGRALDTLEALPDGHPD---EFAYALVISHENQHDETMLQALSLRSG
Mvan_5485|M.vanbaalenii_PYR-1 ATVRGKVLDALDALPDGHPD---AFTFGLVVSHENQHDETMLQALSLRSG
Mb3729c|M.bovis_AF2122/97 ATVRSAALDALAALPEDGDS----FVFAMVISHENQHDETMLQALNLRTG
Rv3703c|M.tuberculosis_H37Rv ATVRSAALDALAALPEDGDS----FVFAMVISHENQHDETMLQALNLRTG
MAV_0400|M.avium_104 RKVRAAVLDTLDALPDDPDAA---FVYAMVVSHENQHDETMLQALNLRSG
MMAR_5214|M.marinum_M RTVRGAVLDALDALDGQGDD----FTFGMVISHESQHNETMLQALNLRSG
MUL_4287|M.ulcerans_Agy99 RTLRGAVLDALDALDGQGDD----FTFGMVISHESQHNETMLQALNLRSG
MAB_0370|M.abscessus_ATCC_1997 HEVRGRVLDRLEALPSDGSARAEEFVYAMVLSHEHQHDETMMQALSIRHG
MSMEG_6249|M.smegmatis_MC2_155 ATVRAKALDTLDTLPEDDPG----FRFALVISHENQHDETMLQALNLREG
TH_0066|M.thermoresistible__bu --------------------------------------------------
Mflv_1316|M.gilvum_PYR-GCK APLLDRGDPLPPGRSGVAGTSVLVTGGEFVLGVDAVTEPFSLDNERPAHT
Mvan_5485|M.vanbaalenii_PYR-1 APLLDRGTSLPPGRPQTAGTSVRVPAGEFVLGVDAVTEPYSLDNERPAHV
Mb3729c|M.bovis_AF2122/97 SPLLAATSALPAGRPRMAGTSVLVAGGPFVLGVDAADEPCSLDNERPAHV
Rv3703c|M.tuberculosis_H37Rv SPLLAATSALPAGRPRMAGTSVLVAGGPFVLGVDAADEPCSLDNERPAHV
MAV_0400|M.avium_104 APLLRDTSVLPAGRPELAGTSVLVPGGEFVLGVDAADEPESLDNERPAHV
MMAR_5214|M.marinum_M PPLLGQTPALPPGRAGLAGTSVEVPAGPFVLGVDGSAEPYSLDNERPAHP
MUL_4287|M.ulcerans_Agy99 PPLLGQTPALPPGRAGLAGTSVEVPAGPFVLGVDGSAEPYSLDNERPAHP
MAB_0370|M.abscessus_ATCC_1997 AALLEAVDPVPPGRPGVAGTSVLVPEGPFVLGVDAVDEPFSLDNERPAHV
MSMEG_6249|M.smegmatis_MC2_155 PPLLDTGIPLPAGRPGVAGTSVLVPGGPFVLGVDALTEPHSLDNERPAHV
TH_0066|M.thermoresistible__bu --------------------------------------------------
Mflv_1316|M.gilvum_PYR-GCK VDVPDFRIGRVPVTNAEWRQFLDDGGYAQRRWWSDAGWTHRQQAGLTRPL
Mvan_5485|M.vanbaalenii_PYR-1 VDVPAFRIGRVPVTNAEWRQFVDDGGYHRRQWWSDAGWAHRRQAGLTAPL
Mb3729c|M.bovis_AF2122/97 VDVPAFRIGRVPVTNGEWQDFIDDGGYTQSRWWSERGWQHRQRAGLTAPQ
Rv3703c|M.tuberculosis_H37Rv VDVPAFRIGRVPVTNGEWQDFIDDGGYTQSRWWSERGWQHRQRAGLTAPQ
MAV_0400|M.avium_104 LDLPAFRIGTIPVTNGEWQQFVADGGYDEPRWWSRRGWQHRQAAGLTAPQ
MMAR_5214|M.marinum_M VDVAAFRIGRVPVTNAEWQHFIDDGGYQQSRWWSPRGWAHRQSAGLSAPQ
MUL_4287|M.ulcerans_Agy99 VDVAAFRIGRVPVTNAEWQHFIDDGGYQQSRWWSPRGWAHRQSAGLSAPQ
MAB_0370|M.abscessus_ATCC_1997 VHLRGFRIGTVPVTNAEWLAFMADGGYRRQELWTEIGWAHRCAEALTAPK
MSMEG_6249|M.smegmatis_MC2_155 VDIPSFRIGRVPVTNAEWREFIDDGGYDQPRWWSPRGWAHRQEAGLVAPQ
TH_0066|M.thermoresistible__bu --------------------------------------------------
Mflv_1316|M.gilvum_PYR-GCK FWNADG-TRTRFGHVEDIPGDEPVQHVTYYEAQAYAAWAGARLPTEIEWE
Mvan_5485|M.vanbaalenii_PYR-1 YWNGDG-SRTRFGYVEEIPGEEPVQHVTYYEAEAYAAWAGARLPTEVEWE
Mb3729c|M.bovis_AF2122/97 FWRSGGRTRTRFGHVEDIPADEPVQHVSYFEAEAYAAWAGARLPTEVEWE
Rv3703c|M.tuberculosis_H37Rv FWRSGGRTRTRFGHVEDIPADEPVQHVSYFEAEAYAAWAGARLPTEVEWE
MAV_0400|M.avium_104 FWHPDARARTRFGHVEDIPADEPVQHVSFFEAEAYAAWAGARLPTEMEWE
MMAR_5214|M.marinum_M FWNADGRTRTRFGYQEDIPADEPVQHVTYFEAEAYAAWAGARLPTEIEWE
MUL_4287|M.ulcerans_Agy99 FWNADGRTRTRFGYQEDIPADEPVQHVTYFEAEAYAAWAGARLPTEIEWE
MAB_0370|M.abscessus_ATCC_1997 FWNQGG-TLTRFGRELQIVPDEPVQHVTFHEAQAYASWAGARLPTEAEWE
MSMEG_6249|M.smegmatis_MC2_155 FWNPDG-TRTRFGHIEEIPGDEPVQHVTFFEAEAYAAWAGARLPTEIEWE
TH_0066|M.thermoresistible__bu --------------------------------------------------
Mflv_1316|M.gilvum_PYR-GCK KACAWDPATGARRRFPWGTAEPTA----DVANLGGGALRPAPVGAFPASA
Mvan_5485|M.vanbaalenii_PYR-1 KACAWDPETNSRRRYPWGATEPTA----EVANLGGRALRPAPVGAYPQSA
Mb3729c|M.bovis_AF2122/97 KACAWDPATGSRRRYPWGTEE-PT---DTYANLGGQTLRPAPVGAYPAGA
Rv3703c|M.tuberculosis_H37Rv KACAWDPATGSRRRYPWGTEE-PT---DTYANLGGQTLRPAPVGAYPAGA
MAV_0400|M.avium_104 KACAWDPSTGTRRRYPWGATP-PS---PAVANLGGAALRPAPVGAYPAGA
MMAR_5214|M.marinum_M KACAWDPVTNSRRRYPWGDSAGPVGNFAAHANLGATALRPAPVGAYPAGA
MUL_4287|M.ulcerans_Agy99 KACAWDPVTNSRRRYPWGDSAGPVGNFAAHANLGATALRPAPVGAYPAGA
MAB_0370|M.abscessus_ATCC_1997 KACVWDPEIGARRRFPWGAEAPAR----DRANLGGGALGPAPVGAYPESA
MSMEG_6249|M.smegmatis_MC2_155 KACAWDPVAGARRRFPWGSAQPSA----ALANLGGDARRPAPVGAYPAGA
TH_0066|M.thermoresistible__bu --------------------------------------------------
Mflv_1316|M.gilvum_PYR-GCK SACGAEQMLGDVWEWTSSPLRPWPGFTPMIYRQYSEPFFDGTASGEYRVL
Mvan_5485|M.vanbaalenii_PYR-1 SAYGAEQMLGDVWEWTSSPLRPWPGFTPMVYERYSQPFFDGTGTGEYRVL
Mb3729c|M.bovis_AF2122/97 SACGAEQMLGDVWEWTTSPLRPWPGFVPMVYERYSQPFFG----GDYRVL
Rv3703c|M.tuberculosis_H37Rv SACGAEQMLGDVWEWTTSPLRPWPGFVPMVYERYSQPFFG----GDYRVL
MAV_0400|M.avium_104 SACGAEQMLGDVWEWTTSPLRPWPGFAPMLYERYSQPFFD----GDYRVL
MMAR_5214|M.marinum_M SAYGAEQMLGDVWEWTASPLRPWPGFAPMIYQRYSQPFFD----GDYRVL
MUL_4287|M.ulcerans_Agy99 SAYGAEQMLGDVWEWTASPLRPWPGFAPMIYQRYSQPFFD----GDYRVL
MAB_0370|M.abscessus_ATCC_1997 SAYGAEQMLGDVWEWTTSPLRPWPGFTPMIYQQYSEPFFD----GDYRVL
MSMEG_6249|M.smegmatis_MC2_155 SAYGAEQMLGDVWEWTSSPLRPWPGFTPMIYERYSTPFFEGTTSGDYRVL
TH_0066|M.thermoresistible__bu ----------------------------MIYQRYSQPFFEGAGSGDYRVL
*:*.:** *** *:****
Mflv_1316|M.gilvum_PYR-GCK RGGSWAVAAGILRPSFRNWDHPIRRQIFSGVRLAWDV-------------
Mvan_5485|M.vanbaalenii_PYR-1 RGGSWAVAPNILRPSFRNWDHPIRRQIFSGVRLAWDDVGAPPACGGPLTR
Mb3729c|M.bovis_AF2122/97 RGGSWAVEPAILRPSFRNWDHPYRRQIFAGVRLAWDI-------------
Rv3703c|M.tuberculosis_H37Rv RGGSWAVEPAILRPSFRNWDHPYRRQIFAGVRLAWDI-------------
MAV_0400|M.avium_104 RGGSWAVEPGILRPSFRNWDHPYRRQIFAGVRLAWDVPGARDHR------
MMAR_5214|M.marinum_M RGGSWAVEPAILRPSFRNWDHPYRRQIFAGVRLAWSIEDAA---------
MUL_4287|M.ulcerans_Agy99 RGGSWAVEPAILRPSFRNWDHPYRRQIFAGVRLAWSIEDAA---------
MAB_0370|M.abscessus_ATCC_1997 RGGSWAVAREIMRPSFRNWDHPVRRQIFSGLRLAWDI-------------
MSMEG_6249|M.smegmatis_MC2_155 RGGSWAVAPGILRPSFRNWDHPIRRQIFSGVRLAWDV-------------
TH_0066|M.thermoresistible__bu RGGSWAVAADILRPSFRNWDHPIRRQIFAGVRLAWDVDRQTARPGPVGGC
******* *:********** *****:*:****.
Mflv_1316|M.gilvum_PYR-GCK ------
Mvan_5485|M.vanbaalenii_PYR-1 RVDGYV
Mb3729c|M.bovis_AF2122/97 ------
Rv3703c|M.tuberculosis_H37Rv ------
MAV_0400|M.avium_104 ------
MMAR_5214|M.marinum_M ------
MUL_4287|M.ulcerans_Agy99 ------
MAB_0370|M.abscessus_ATCC_1997 ------
MSMEG_6249|M.smegmatis_MC2_155 ------
TH_0066|M.thermoresistible__bu ------