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M. gilvum PYR-GCK Mflv_1245 (-)

annotation: glycerol dehydratase
coordinates: 1298499 - 1300739
length: 746

VADELGRFRVLNSKPVNLDGFSVPDAALGLVAMSSPHDPAPSLVIRDGAVVELDSKDVAEFDVIDEFIAR
YGIDLSVAEEAMALDDETLARMVVDINVPRAGVVRLIGGTTPAKLARVVALLSPVEMQMAMVKMRARRTP
SNQAHVTNQLDDPLLIAADAASAVAYGFREVETTVPVLGDAPSNAVALLIGSQVGTPGAMAQCSIEEALE
LRLGLRGLTSYAETISIYGTEQVFIDGDDTPFSKAILTSAYASRGLKMRVTSGGGAEVLMGAAQKCSILY
LESRCVSLARALGSQGVQNGGIDGVGVVASVPEGMKELLAENLMVMMRDLESCAGNDNLISESDIRRSAH
TLPVLLAGADFIFSGFGSIPRYDNAFALSNFNSDDMDDFLVLQRDWGADGGLRTVSPEHLEAVRRRAAQA
VQAVYRDLGLADYDDARVEDVVAANGSRDLPAGHPKMVAEAAASIEARQLTVFDVIAALHRTGFTEEAEA
ITTLTRERLRGDQLQTSAIFDEQFRVFSKLTDPNDYRGPATGYALTEQRRAEIDAIRQARSGAELTVDQE
EHRGHVVVTDVEPAHQGSDPREVCIGLSPAWGRSVWLTLCGLTVGEVLRQIAAGLEEEGCIARTVRVCST
IDTGLIGLTAARLSGSGIGIGLQGKGTALIHRRDLAPLANLELFSVAPLLTAKMYRELGKNAARHAKGMA
PVPIFTGGTDESISARYHARAVALVALERDACEPGRAPVTVKVEAR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1245--100% (746)glycerol dehydratase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_6321-0.086.35% (740) glycerol dehydratase large subunit
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5563-0.094.35% (744) glycerol dehydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1245|M.gilvum_PYR-GCK          -----------MADELGRFRVLNSKPVNLDGFSVPDAALGLVAMSSPHDP
Mvan_5563|M.vanbaalenii_PYR-1       -----------MADELGRFRVLNSKPVNLDGFSVPDAGLGLVAMSSPHDP
MSMEG_6321|M.smegmatis_MC2_155      MVAVTESGDPGQSPELGRMRILDAKPVNLDGFSVPDPDLGLAAMSSPHDP
                                                : ****:*:*::************. ***.********

Mflv_1245|M.gilvum_PYR-GCK          APSLVIRDGAVVELDSKDVAEFDVIDEFIARYGIDLSVAEEAMALDDETL
Mvan_5563|M.vanbaalenii_PYR-1       APSLKIRGGEVVELDGKGAGEFDVIDEFIARYGIDLTVAEEAMALGDETL
MSMEG_6321|M.smegmatis_MC2_155      QPSLVIRDGRVVEMDGKAAEDFDVIDEFIARYGLDLDVAPEAMAMSDIDL
                                     *** **.* ***:*.* . :************:** ** ****:.*  *

Mflv_1245|M.gilvum_PYR-GCK          ARMVVDINVPRAGVVRLIGGTTPAKLARVVALLSPVEMQMAMVKMRARRT
Mvan_5563|M.vanbaalenii_PYR-1       ARMVVDINVPRAEVVRLIGGTTPAKLARVVALLSPVEMQMAMAKMRARRT
MSMEG_6321|M.smegmatis_MC2_155      ARMAVDINVPRAEVVRLIAGTTPAKLAKVIAVLTPVEMQAAMAKMRARRT
                                    ***.******** *****.********:*:*:*:***** **.*******

Mflv_1245|M.gilvum_PYR-GCK          PSNQAHVTNQLDDPLLIAADAASAVAYGFREVETTVPVLGDAPSNAVALL
Mvan_5563|M.vanbaalenii_PYR-1       PSNQAHVTNQLDDPLLIAADAASAVAYGFREVETTVPVLGDAPSNAVALL
MSMEG_6321|M.smegmatis_MC2_155      PSNQAHVTNQLDDPLLIAADAASAVAYGFREVETTVPVLADAPSNAVALL
                                    ***************************************.**********

Mflv_1245|M.gilvum_PYR-GCK          IGSQVGTPGAMAQCSIEEALELRLGLRGLTSYAETISIYGTEQVFIDGDD
Mvan_5563|M.vanbaalenii_PYR-1       IGSQVGSPGAMAQCSIEEALELRLGLRGLTSYAETISIYGTEQVFVDGDD
MSMEG_6321|M.smegmatis_MC2_155      IGSQVGVPGAMAQCSIEEALELRLGLRGLTSYAETISIYGTEQVFVDGDD
                                    ****** **************************************:****

Mflv_1245|M.gilvum_PYR-GCK          TPFSKAILTSAYASRGLKMRVTSGGGAEVLMGAAQKCSILYLESRCVSLA
Mvan_5563|M.vanbaalenii_PYR-1       TPFSKAILTSAYASRGLKMRVTSGGGAEVLMGAAEKCSILYLESRCVSLA
MSMEG_6321|M.smegmatis_MC2_155      TPFSKAILTSAYASRGLKMRVTSGGGAEVLMGAAEKCSILYLESRCVSLA
                                    **********************************:***************

Mflv_1245|M.gilvum_PYR-GCK          RALGSQGVQNGGIDGVGVVASVPEGMKELLAENLMVMMRDLESCAGNDNL
Mvan_5563|M.vanbaalenii_PYR-1       RALGSQGVQNGGIDGVGVVASVPEGMKELLAENLMVMMRDLESCAGNDNL
MSMEG_6321|M.smegmatis_MC2_155      RALGSQGVQNGGIDGVGVVASVPDGMKELLAENLMVMMRDLESCAGNDNL
                                    ***********************:**************************

Mflv_1245|M.gilvum_PYR-GCK          ISESDIRRSAHTLPVLLAGADFIFSGFGSIPRYDNAFALSNFNSDDMDDF
Mvan_5563|M.vanbaalenii_PYR-1       ISESDIRRSAHTLPVLLAGADFVFSGFGSIPRYDNAFALSNFNSDDMDDF
MSMEG_6321|M.smegmatis_MC2_155      ISESDIRRSAHTLPVLLAGADFIFSGFGSIPRYDNAFALSNFNSDDMDDF
                                    **********************:***************************

Mflv_1245|M.gilvum_PYR-GCK          LVLQRDWGADGGLRTVSPEHLEAVRRRAAQAVQAVYRDLGLADYDDARVE
Mvan_5563|M.vanbaalenii_PYR-1       LVLQRDWGADGGLRTVSPEHLEAVRRRAAKAVQAVYRDLGLADYEDARVE
MSMEG_6321|M.smegmatis_MC2_155      LVLQRDWGADGGLRTVPADQLAAVRRRAARAVQAVYRDLGLADFDDQHIE
                                    ****************..::* *******:*************::* ::*

Mflv_1245|M.gilvum_PYR-GCK          DVVAANGSRDLPAGHPKMVAEAAASIEARQLTVFDVIAALHRTGFTEEAE
Mvan_5563|M.vanbaalenii_PYR-1       EVVAANGSRDLPAGHPKMVAEAAASIEARQLTVFDVIASLHRTGFTDEAE
MSMEG_6321|M.smegmatis_MC2_155      NVVAANGSRDLPPGDPKAVLEAANAIEAKQLTVFDVVASLKRTGFDPEAE
                                    :***********.*.** * *** :***:*******:*:*:****  ***

Mflv_1245|M.gilvum_PYR-GCK          AITTLTRERLRGDQLQTSAIFDEQFRVFSKLTDPNDYRGPATGYALTEQR
Mvan_5563|M.vanbaalenii_PYR-1       AITTLTRERLRGDQLQTSAIFDEKFRVLSKLTDPNDYTGPATGYALTDRR
MSMEG_6321|M.smegmatis_MC2_155      AIMRLTAERMRGDQLQTSAIFDEQFRVLSKITDPNDYAGPGTGYTLSEQR
                                    **  ** **:*************:***:**:****** **.***:*:::*

Mflv_1245|M.gilvum_PYR-GCK          RAEIDAIRQARSGAELTVDQEEHRGHVVVTDVEPAHQGSDPREVCIGLSP
Mvan_5563|M.vanbaalenii_PYR-1       RAEIDAIRQARSSAELTADQESYRGHVLVTDVEPAQQGSDPREVCIGLSP
MSMEG_6321|M.smegmatis_MC2_155      RAEIDNIRQQRSAAELTADQAEHAGHITVTEIEPARQGSDPREVCIGLSP
                                    ***** *** **.****.** .: **: **::***:**************

Mflv_1245|M.gilvum_PYR-GCK          AWGRSVWLTLCGLTVGEVLRQIAAGLEEEGCIARTVRVCSTIDTGLIGLT
Mvan_5563|M.vanbaalenii_PYR-1       AWGRSVWLTLCGLTIGEVLRQISAGLEEEGCIARPVRVRSTIDVGLIGLT
MSMEG_6321|M.smegmatis_MC2_155      ALGRSVWLSLCGLPIGEVIRQISAGLEEEGCVPRFVRVRSTIDVGLIGLT
                                    * ******:****.:***:***:********:.* *** ****.******

Mflv_1245|M.gilvum_PYR-GCK          AARLSGSGIGIGLQGKGTALIHRRDLAPLANLELFSVAPLLTAKMYRELG
Mvan_5563|M.vanbaalenii_PYR-1       AARLSGSGIGIGLQGKGTALIHRRDLAPLANLELFSVAPLLTAKMYRELG
MSMEG_6321|M.smegmatis_MC2_155      AAKLAGSGIGIGLQGKGTALIHRRDLAPLANLELFSVAPLLTARNYRELG
                                    **:*:**************************************: *****

Mflv_1245|M.gilvum_PYR-GCK          KNAARHAKGMAPVPIFTGGTDESISARYHARAVALVALERDACEPGRAPV
Mvan_5563|M.vanbaalenii_PYR-1       KNAARHAKGMAPVPIFTGGTDESISARYHARAVALVALERESCEPGQPPV
MSMEG_6321|M.smegmatis_MC2_155      RNAARHAKGMAPVPILTGGTDESISARYHARAVALVALERQASEPGEAPV
                                    :**************:************************::.***..**

Mflv_1245|M.gilvum_PYR-GCK          TVKVEAR
Mvan_5563|M.vanbaalenii_PYR-1       TVKVEWP
MSMEG_6321|M.smegmatis_MC2_155      TVEVRRP
                                    **:*.