For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VADVMRLVRGCLWVMFGLFFLFPLYAMADFSTRNLISDGRTWQAWANLVTDDALYRSIVVSLLLAVLTVV AMLVLLVPTMIWVRLRAPWAKGLVEFLCLLPLTIPALVIVVGLRNVYLWVVYFLGESALTLTFVYVIVVL PFAYRAIDAALSAIDLQTLSEAARSLGAGWFTTITRVVVPNIWSGILSAAFISIAVVLGEYTIASLSGYE TLQVQIVLIGKSDGPTSVAASLATLLFGFALLLILSLVTRGRRNVGVTT
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_1082 | - | - | 100% (259) | binding-protein-dependent transport systems inner membrane component |
M. gilvum PYR-GCK | Mflv_2679 | - | 2e-12 | 26.05% (215) | sulfate ABC transporter, inner membrane subunit CysT |
M. gilvum PYR-GCK | Mflv_3135 | - | 5e-10 | 26.12% (245) | binding-protein-dependent transport systems inner membrane |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2421c | cysT | 2e-13 | 28.51% (221) | sulfate-transport integral membrane protein ABC transporter |
M. tuberculosis H37Rv | Rv2399c | cysT | 2e-13 | 28.51% (221) | sulfate-transport integral membrane protein ABC transporter |
M. leprae Br4923 | MLBr_02093 | pstA1 | 5e-08 | 28.66% (164) | membrane-bound component of phosphate transport |
M. abscessus ATCC 19977 | MAB_1504 | - | 2e-14 | 29.70% (202) | ABC transporter permease |
M. marinum M | MMAR_3717 | cysT | 9e-12 | 26.38% (254) | sulfate-transport integral membrane protein ABC transporter |
M. avium 104 | MAV_1783 | cysT | 2e-14 | 28.80% (250) | sulfate ABC transporter, permease protein CysT |
M. smegmatis MC2 155 | MSMEG_6522 | - | 1e-120 | 87.50% (248) | ABC transporter, inner membrane subunit |
M. thermoresistible (build 8) | TH_1446 | cysT | 6e-15 | 28.29% (251) | PROBABLE SULFATE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC |
M. ulcerans Agy99 | MUL_3660 | cysT | 2e-11 | 26.95% (256) | sulfate-transport integral membrane protein ABC transporter |
M. vanbaalenii PYR-1 | Mvan_5740 | - | 1e-129 | 92.83% (251) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1082|M.gilvum_PYR-GCK --------------------------------MADVMRLVRGCLWVMFGL Mvan_5740|M.vanbaalenii_PYR-1 ---------------------------------------MRGALWVMFGL MSMEG_6522|M.smegmatis_MC2_155 -------------------MSTSTTTGTSTGSNRALRRAVRATLWVLFGL Mb2421c|M.bovis_AF2122/97 -------------MTESLVGER----RAPQFRARL--SGPAGPPSVRVGM Rv2399c|M.tuberculosis_H37Rv -------------MTESLVGER----RAPQFRARL--SGPAGPPSVRVGM MAV_1783|M.avium_104 ----------MTAITPDPLAIRPELGGDPGHQPVP--GRGRGTTALRVGV MMAR_3717|M.marinum_M MTVTAHSGQSDPPAVAPDPGQRAD--GGPQWISGLGRSGRRGATALQVGV MUL_3660|M.ulcerans_Agy99 MTVTAHSGQSDPPAVAPDLGQRAD--GGPQWISGPGRSGRRGATALQVGV TH_1446|M.thermoresistible__bu ---------------VSAVLPRSE--TTPAAPPGW---GRGGATSLRVGI MAB_1504|M.abscessus_ATCC_1997 -----------------------------------MLLWNGRSRLILWSV MLBr_02093|M.leprae_Br4923 -------------MNLDTLDRPVKAVVLRPISVRRRIKNNVATMFFFTSF . .. Mflv_1082|M.gilvum_PYR-GCK FFLFP-LYAMADFSTRNLISDGRTWQ-----AWANLVTDDALYRSIVVSL Mvan_5740|M.vanbaalenii_PYR-1 FFLFP-LYAMADFSTRNLIAGGRTWR-----AWANLFADQALYQAIVVSL MSMEG_6522|M.smegmatis_MC2_155 FFLFP-LYAMADFSTRNLISGGRTLA-----AWGNLVADEALYRAIVISL Mb2421c|M.bovis_AF2122/97 AVVWLSVIVLLPLAAIVWQAAGGGWR-----AFWLAVSSHAAMESFRVTL Rv2399c|M.tuberculosis_H37Rv AVVWLSVIVLLPLAAIVWQAAGGGWR-----AFWLAVSSHAAMESFRVTL MAV_1783|M.avium_104 ATVWLSVIVLLPLAAIAWQSAGGGWH-----VFWLAVTSNAALESFRVTL MMAR_3717|M.marinum_M SMVWLSVIVLLPLAAIAWQAADGGWH-----AFWLSVSSHAALESLRVTL MUL_3660|M.ulcerans_Agy99 SMVWLSVIVLLPLAAIAWQAADGGWH-----AFWLSVSSHAALESLRVTL TH_1446|M.thermoresistible__bu ATVWLSIIVLLPLAAILWQSTNGGWD-----AFRDAVTANAALTSLRVTL MAB_1504|M.abscessus_ATCC_1997 FAVVITVVFIAPIATVVLAGFSGAWTGPLPTQLSFMRYEKALGGDDLASM MLBr_02093|M.leprae_Br4923 LIALVPLVWLLSVVVARGFYAVTRFDWWT-HSLRGVMPEEFAGGVYHALY : : . . . Mflv_1082|M.gilvum_PYR-GCK LLAVLTVVAMLVLLVPTMIWVRLRAPWA----KGLVEFLCLLPLTIPALV Mvan_5740|M.vanbaalenii_PYR-1 LLAVFTVAAMLVLLVPTMIWVRLRAPWA----KGLVEFMCLLPLTIPALV MSMEG_6522|M.smegmatis_MC2_155 LLAVFTVVAMLVLLVPTMIWVRLRARWA----RRIVEFLCLLPLTIPALV Mb2421c|M.bovis_AF2122/97 TISTA-VTVINLVFGLLIAWVLVRDDFAG---KRIVDAIIDLPFALPTIV Rv2399c|M.tuberculosis_H37Rv TISTA-VTVINLVFGLLIAWVLVRDDFAG---KRIVDAIIDLPFALPTIV MAV_1783|M.avium_104 TISAG-VTVLNLVFGLVIAWVLVRDEFPG---KRLVDAIIDLPFALPTIV MMAR_3717|M.marinum_M TVSAG-VTLLNTVFGLLIAWVLIRDEFVG---KRLVDAVIDLPFALPTIV MUL_3660|M.ulcerans_Agy99 TVSAG-VTLLNAVFGLLIAWGLIRDEFVG---KRLVDAVIDLPFALPTIV TH_1446|M.thermoresistible__bu TIAAG-VTVVNTVFGLMVAWVLTRDEFIG---KRLVNSVIDLPFALPTIV MAB_1504|M.abscessus_ATCC_1997 AVSLQTAVMSSGVALLLGTWAALSVREVPSWLRRVIDAVFHLPIAIPSVA MLBr_02093|M.leprae_Br4923 GSLVQAVVAAIMAVPLGSMTAVYLVEYGSGPFVRVTTFMVDVLAGVPSIV .. : : : :*::. Mflv_1082|M.gilvum_PYR-GCK IVVGLRNVY---LWVVYFLGESALTLTFVYVIVVLPFAYRAIDAALSAID Mvan_5740|M.vanbaalenii_PYR-1 IVVGLRNVY---LWVTYFLGESALTLTFVYVVIVLPFAYRAIDAALSAID MSMEG_6522|M.smegmatis_MC2_155 IVVGLRNVY---LWVTYFLGESALTLTFVYVVLVLPFAYRAIDSALAAID Mb2421c|M.bovis_AF2122/97 ASLVMLALYGNNSPVGLHFQHTATGVGVALAFVTLPFVVRAVQPVLLEID Rv2399c|M.tuberculosis_H37Rv ASLVMLALYGNNSPVGLHFQHTATGVGVALAFVTLPFVVRAVQPVLLEID MAV_1783|M.avium_104 ASLVMLALYGNNSPVGLHLQHTAAGVAVALAFVTLPFVVRAVQPVLLELD MMAR_3717|M.marinum_M ASLVMLALYGHNSPLGLHLQHTVWGVGVALAFVTLPFVVRAVQPVLLELD MUL_3660|M.ulcerans_Agy99 ASLVMLALYGHNSPLGLHLQHTVWGVGVALAFVTLPFVVRAVQPVLLELD TH_1446|M.thermoresistible__bu ASLVMLALYGPASPVDIHLQHTRWGVGVALLFVTLPFVVRSVQPVLLELD MAB_1504|M.abscessus_ATCC_1997 IGLGLLTAFN---EPPLLLGGTKWIVIVAHTALVLAFAFSSVSAALERLD MLBr_02093|M.leprae_Br4923 AALFIFCLW----IATLGFQQSAFAVSLALVLLMLPVVVRSTEEILRLVP : : : : : : .. : *... : . * : Mflv_1082|M.gilvum_PYR-GCK LQTLSEAARSLGAGWFTTITRVVVPNIWSGILSAAFISIAVVLGEYTIAS Mvan_5740|M.vanbaalenii_PYR-1 LQTLSEAARSLGAGWLTTITRVVVPNIWSGILSAAFISIAVVLGEFTIAS MSMEG_6522|M.smegmatis_MC2_155 LQTLSEAARSLGAGWFTTITRVIVPNIWSGILSAAFISIAVVLGEYTIAS Mb2421c|M.bovis_AF2122/97 RET-EEAAASLGANGAKIFTSVVLPSLTPALLSGAGLAFSRAIGEFGSVV Rv2399c|M.tuberculosis_H37Rv RET-EEAAASLGANGAKIFTSVVLPSLTPALLSGAGLAFSRAIGEFGSVV MAV_1783|M.avium_104 RET-EEAAASLGASGPKIFTSVVLPALLPALLSGAGLAFSRAIGEFGSVV MMAR_3717|M.marinum_M RET-EEAAASLGATGWKVFTSVIFPSLMPALLSGAGLAFSRAIGEFGSVV MUL_3660|M.ulcerans_Agy99 RET-EEAAASLGATGWKVFTSVIFPSLMPALLSGAGLAFSRAIGEFGSVV TH_1446|M.thermoresistible__bu RET-EEAAASLGANNLTIFTRVVLPALLPALLSGAGLAFSRAIGEFGSVV MAB_1504|M.abscessus_ATCC_1997 PAY-RQVAESLGAGSVRVVRTVTLPLLMPSLGAAAGLAIALSMGELGATV MLBr_02093|M.leprae_Br4923 DEL-REACYALGIPKWKTIVRIVFPIATPGIISGVLLSIARVIGETAPVL :.. :** . : .* ..: :.. :::: :** . Mflv_1082|M.gilvum_PYR-GCK LSG---------------YETLQVQIVLIGKSDGPTSVAASLATLLFGFA Mvan_5740|M.vanbaalenii_PYR-1 LSG---------------YETLQVQIVLIGKSDGPTSVAASLATLLFGFV MSMEG_6522|M.smegmatis_MC2_155 LSG---------------FETLQVQIVLIGKSDGPTSVAASLAVLLLGFV Mb2421c|M.bovis_AF2122/97 LIGGAV--------PGKTEVSSQWIRTLIENDDRTGAAAISVVLLSISFI Rv2399c|M.tuberculosis_H37Rv LIGGAV--------PGKTEVSSQWIRTLIENDDRTGAAAISVVLLSISFI MAV_1783|M.avium_104 LIGGAV--------PGKTEVSSQWIRTLIENDDRTGAAAISIVLLAISFV MMAR_3717|M.marinum_M LIGGAV--------PGETEVSSQWIRTLIENDDRTGAAAISIVLLSISFA MUL_3660|M.ulcerans_Agy99 LIGGAV--------PGETEVSSQWIRTLIENDDRTGAAAISIVLLSISFA TH_1446|M.thermoresistible__bu LIGGAV--------PGETEVASQWIRTLIENDDRTGAAAVSIVLLVISFL MAB_1504|M.abscessus_ATCC_1997 MVYP--------------SSWRTLPVTIFGLSDRGQVFSAAASTTLLLMV MLBr_02093|M.leprae_Br4923 VLVGYSRSINFDIFDGNMASLPLLIYTELTNPEYAGFLRVWGAALTLIIL : . : : : : Mflv_1082|M.gilvum_PYR-GCK LLLILSLVTRGRR-NVGVTT--- Mvan_5740|M.vanbaalenii_PYR-1 LLLILSLVTRGRR-NVGVTV--- MSMEG_6522|M.smegmatis_MC2_155 LLLALAVLTRGRRRTLGDQG--- Mb2421c|M.bovis_AF2122/97 VLLILRVVGARAAKREEMAA--- Rv2399c|M.tuberculosis_H37Rv VLLILRVVGARAAKREEMAA--- MAV_1783|M.avium_104 VLLILRVVGGRAAKREELAA--- MMAR_3717|M.marinum_M VLLVLRVLGARAAKREELAP--- MUL_3660|M.ulcerans_Agy99 VLLVLRVLGARAAKREELAP--- TH_1446|M.thermoresistible__bu VLLVLRVIGSRAAKREEQTA--- MAB_1504|M.abscessus_ATCC_1997 TLLALLVVGRLRGKVAFR----- MLBr_02093|M.leprae_Br4923 VAGINLFGAAFRFLATRRCSGCR .