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AGFRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRAVSAGIVIAVLICLGAVLLAYFKPLGKR GDDTLLVDRTTNQLYLVLPDSSQLRPVYNLTSARLILGEGKTPVAVKSDELDRTPKGLPVGIPGAPYATA VSAPSESQWSLCDTVVKPDRVAPAVESSVLVTPLALDASVGAMRPEQGMLVTYKDRTWLVTPQGRHLIDM ADRAVTSAVGIPVTARAAPISEGLFNALPDEGPWRLPDIPGAGTPNTVGLPPALVIGSVFVTVTDMGEQT DEQGYVVLPSGVAKVNSTTAAALRATNSYGLIEPPSMESSVVARIPEQVYTSPLPDRPMDVLGRQEVPTL CWSWQRVAGDQAPKMTVIAGRRLPLPPSALATGIDQISGDATVYVDGGQYIQLQSPEPRYGENLYYIDPQ GVRYGLPDQETAARLGLSAPRTAPWQVVSLLVDGPVLSQQAALIEHDTLPPNPNPRRAGGGSTAQANVGG GG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0772 | - | - | 100% (493) | hypothetical protein Mflv_0772 |
| M. gilvum PYR-GCK | Mflv_0328 | - | 1e-73 | 37.09% (488) | hypothetical protein Mflv_0328 |
| M. gilvum PYR-GCK | Mflv_4962 | - | 1e-46 | 31.46% (480) | hypothetical protein Mflv_4962 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3899 | - | 0.0 | 63.28% (482) | hypothetical protein Mb3899 |
| M. tuberculosis H37Rv | Rv3869 | - | 0.0 | 63.28% (482) | hypothetical protein Rv3869 |
| M. leprae Br4923 | MLBr_00054 | - | 1e-174 | 61.04% (480) | hypothetical protein MLBr_00054 |
| M. abscessus ATCC 19977 | MAB_2233c | - | 8e-64 | 33.83% (470) | hypothetical protein MAB_2233c |
| M. marinum M | MMAR_5444 | - | 0.0 | 63.20% (481) | hypothetical protein MMAR_5444 |
| M. avium 104 | MAV_4870 | - | 8e-74 | 35.24% (508) | hypothetical protein MAV_4870 |
| M. smegmatis MC2 155 | MSMEG_0060 | - | 0.0 | 71.58% (482) | hypothetical protein MSMEG_0060 |
| M. thermoresistible (build 8) | TH_3503 | - | 0.0 | 75.20% (492) | PUTATIVE protein of unknown function DUF690 |
| M. ulcerans Agy99 | MUL_1205 | - | 3e-72 | 35.70% (493) | hypothetical protein MUL_1205 |
| M. vanbaalenii PYR-1 | Mvan_0073 | - | 0.0 | 85.25% (495) | hypothetical protein Mvan_0073 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3899|M.bovis_AF2122/97 --------------------------------MGLRLTTKVQVSGWRFLL
Rv3869|M.tuberculosis_H37Rv --------------------------------MGLRLTTKVQVSGWRFLL
MMAR_5444|M.marinum_M --------------------------------MGLRLTTKVQVSGWRFLL
MLBr_00054|M.leprae_Br4923 --------------------------------MGLRLTTKVQVSGWRFLL
Mflv_0772|M.gilvum_PYR-GCK -------------------------------MAGFRLTTKVQVSGWRFLL
Mvan_0073|M.vanbaalenii_PYR-1 -------------------------------MAGFRLTTKVQVSGWRFLL
TH_3503|M.thermoresistible__bu -------------------------------MAGFRLTTKVQVSGWRFLL
MSMEG_0060|M.smegmatis_MC2_155 -------------------------------MAGFRLTTKVQVSGWRFLL
MAV_4870|M.avium_104 MTANNDPDD-----RRSFTSRTPVNDNPDQVQYRRGFVTRHQVSGWRFVM
MUL_1205|M.ulcerans_Agy99 MTTN-EPDGEWAGARRSFTSRTPVNDNPDKVEYRRGFVTRHQVTGWRFVM
MAB_2233c|M.abscessus_ATCC_199 MSDNRDNNAN--SERRAFASRTPASENPEPLKYRRGFVTGHQVTGWRFVM
:.* **:****::
Mb3899|M.bovis_AF2122/97 RRLEHAIVRRDTRMFDDPLQFYSRSIALGIVVAVLILAGAALLAYFKPQG
Rv3869|M.tuberculosis_H37Rv RRLEHAIVRRDTRMFDDPLQFYSRSIALGIVVAVLILAGAALLAYFKPQG
MMAR_5444|M.marinum_M RRVEHAIVRRDTRMFDDPLQFYSRSIALGIVVAVLILAGAGLLAYFKPAG
MLBr_00054|M.leprae_Br4923 RRVEHAIVRRDTRMFDDPLQFYSRSIALGIVVAVALLIGAVLLAYFKPQG
Mflv_0772|M.gilvum_PYR-GCK RRVEHAIVRRDTRMFDDPLQFYSRAVSAGIVIAVLICLGAVLLAYFKPLG
Mvan_0073|M.vanbaalenii_PYR-1 RRVEHAIVRRDTRMFDDPLQFYSRAVTTGIVIAVLICLGAVLLAYFKPLG
TH_3503|M.thermoresistible__bu RRVEHAIVRRDTRMFDDPLQFYSRAVQAGIVISVLICLGAVLLAYFKPLG
MSMEG_0060|M.smegmatis_MC2_155 RRVEHAIVRRDTRMFDDPLQFYSRAVFAGVVVSVLICLGAALMAYFKPLG
MAV_4870|M.avium_104 RRIASGIALHDTRMLVDPLRTQSRAVAMGAVLLVTGLAGCFVFSLIRPNG
MUL_1205|M.ulcerans_Agy99 RRIASGIALHDTRMLVDPLRTQSRSVLMGVLIFITGLVGCFVFSLIRPNG
MAB_2233c|M.abscessus_ATCC_199 RRIASGVALHDARMLVDPLRTQSRAFGMGAVVVVTGLVGCFVFSLLRPSG
**: .:. :*:**: ***: **:. * :: : *. ::: ::* *
Mb3899|M.bovis_AF2122/97 KLGGTSLFTDRATNQLYVLLSG--QLHPVYNLTSARLVLGNPANPATVKS
Rv3869|M.tuberculosis_H37Rv KLGGTSLFTDRATNQLYVLLSG--QLHPVYNLTSARLVLGNPANPATVKS
MMAR_5444|M.marinum_M KLGGSNLLTDRATNQLYVLLSG--QLHPVYNLTSARLVLGTPAAPVTVKS
MLBr_00054|M.leprae_Br4923 KLGASTLLTDRATNQLYVLLSG--HLYPVYNLTSARLALGKPANPAAVKS
Mflv_0772|M.gilvum_PYR-GCK KRGDDTLLVDRTTNQLYLVLPDSSQLRPVYNLTSARLILGEGKTPVAVKS
Mvan_0073|M.vanbaalenii_PYR-1 KRGGDTLLVDRTTNQLFIVLPDSGQLRPVYNLTSARLILGDGKTPVAVKS
TH_3503|M.thermoresistible__bu KRGGDTLLVDRTTNQLYVTLPGSDQLRPVYNLTSARLVLANNATPSAVKS
MSMEG_0060|M.smegmatis_MC2_155 KQGSDQLLVDRTTNQLYVMLPGSNQLRPVYNLTSARLVLGNASNPVAVKS
MAV_4870|M.avium_104 TAGTNAVLADRSTAALYVRVGD--DLHPVLNLTSARLIVGKPVNPTTVKS
MUL_1205|M.ulcerans_Agy99 QVGSNAVLADRSTAALYVRVGD--TLHPVLNLTSARLIVGHPVNPTTVKS
MAB_2233c|M.abscessus_ATCC_199 IAGTDPILADRSTAALYVRVGD--NLHPVLNLTSARLIAGKAADPTMVKS
* ::.**:* *:: : . * ** ******* . * ***
Mb3899|M.bovis_AF2122/97 SELSKLPMGQTVGIPGAPYATPVSAGSTSIWTLCDTVARADS----TSPV
Rv3869|M.tuberculosis_H37Rv SELSKLPMGQTVGIPGAPYATPVSAGSTSIWTLCDTVARADS----TSPV
MMAR_5444|M.marinum_M SELSQLPLGQTIGIPGAPYATPVSGDTTSTWTLCDTVSRAGT----ASAS
MLBr_00054|M.leprae_Br4923 SELTKLPIGQTIGIPGAPYATPVSGDSSSTWTLCDTVAKIES----ESPA
Mflv_0772|M.gilvum_PYR-GCK DELDRTPKGLPVGIPGAPYATAVSAPSESQWSLCDTVVKPDR----VAPA
Mvan_0073|M.vanbaalenii_PYR-1 QELDKMPKGQPVGIPGAPYATPVASSAESQWTLCDTVIKPDS----VAPA
TH_3503|M.thermoresistible__bu EELDRMPKGQPIGIPGAPYATPLAAP-QSTWTLCDTVTRPES----VSPT
MSMEG_0060|M.smegmatis_MC2_155 EELNRISKGQSIGIPGAPYATPTGTP-ASQWTLCDTVAKPDS----SAPK
MAV_4870|M.avium_104 AELDRFPRGNLLGIPGAPERMVQNPSTDANWTVCDSVSEPAPGGHGAHST
MUL_1205|M.ulcerans_Agy99 TELDRFPRGNLIGIPGAPERMVQSEARDSDWTVCDAISSGSQGGSAAHST
MAB_2233c|M.abscessus_ATCC_199 TQLDKFPRGNLIGIPGAPERMVQAKATDAAWAVCEAGQTSTD------NR
:* : . * :****** : *::*::
Mb3899|M.bovis_AF2122/97 VQTAVIAMPLEIDASIDPLQSHEAVLVSYQGETWIVTTKGRHAIDLTDRA
Rv3869|M.tuberculosis_H37Rv VQTAVIAMPLEIDASIDPLQSHEAVLVSYQGETWIVTTKGRHAIDLTDRA
MMAR_5444|M.marinum_M VETSLLVMPLRIDAAIDPIEPNEAMLADYHGQTWIVTSKGRHSIDLNDRA
MLBr_00054|M.leprae_Br4923 VQTSVIARSLQIDPAINPLQPNEALLASYRDKTWLVNSKGRHSIDLADRA
Mflv_0772|M.gilvum_PYR-GCK VESSVLVTPLALDASVGAMRPEQGMLVTYKDRTWLVTPQGRHLIDMADRA
Mvan_0073|M.vanbaalenii_PYR-1 VESSVLITPLALDASVGAMRPEQGMLVSFRDQNWLVTEAGRHLIDLADRA
TH_3503|M.thermoresistible__bu LRTSVLVLPLATDTAVGPMNPNQGMLVTYQGKPWLVTDRGRHSIDLADRA
MSMEG_0060|M.smegmatis_MC2_155 VETSILIRTLAIDSGVGPIRADQGMLVSYEGANWLITEGGRHSIDLADRA
MAV_4870|M.avium_104 GVTVIAGRPDSSGARAAALPSQQAILAERDGGTWLLWNGRRSQINLADHA
MUL_1205|M.ulcerans_Agy99 GVTVIAGSPEPSGHRATALGAGQVILVNDGTSSWLLWDGKRSRMDLADHA
MAB_2233c|M.abscessus_ATCC_199 SVTVIAGPLDTDGDKAADLPRDRAAVVSSEAGTWLLWDGKRSALNLGDVA
: : . : . :. *:: * ::: * *
Mb3899|M.bovis_AF2122/97 LTSSMGIP----VTARPTPISEGMFNALPDMGPWQLPPIPAAGAPNSLGL
Rv3869|M.tuberculosis_H37Rv LTSSMGIP----VTARPTPISEGMFNALPDMGPWQLPPIPAAGAPNSLGL
MMAR_5444|M.marinum_M LTSAVGIP----ITAQTVPISEGMFNALPARGPWQLPPIPAAGEPNTLGL
MLBr_00054|M.leprae_Br4923 LTSAIGIS----VNVKPTPLSEGLFNALPDVGRWELPTIPDTGAPNSLGL
Mflv_0772|M.gilvum_PYR-GCK VTSAVGIP----VTARAAPISEGLFNALPDEGPWRLPDIPGAGTPNTVGL
Mvan_0073|M.vanbaalenii_PYR-1 VTSAVGIP----VTARSAPISEGLFNALPNAGPWRLPDIPAGGSPNSVGL
TH_3503|M.thermoresistible__bu VTSAVGIP----VTARATPISTGLFNALPNAGPWQVPDVPAAGAPNTVGL
MSMEG_0060|M.smegmatis_MC2_155 VTSAVGIP----VTAKPTPISQGLFNALPNRGPWQLPQIPAAGAPNSVGL
MAV_4870|M.avium_104 VTNALGLTENNSELPAPRPIALGLFNAIPEAPSLSAPGIPNAGAPAPFAV
MUL_1205|M.ulcerans_Agy99 VTNALGFA---TDLPAPRPIAPGLFNAIPEAAPLAAPAIPDAGNPAAFAV
MAB_2233c|M.abscessus_ATCC_199 VTSALGFT----APPAVRPVTTRLLNAIPEAPALVIPAIAGAGAPTSYPL
:*.::*:. *:: ::**:* * :. * * . :
Mb3899|M.bovis_AF2122/97 PDDLVIGSVFQIHTDK-----GPQYYVVLPDGIAQVNATTAAALRATQAH
Rv3869|M.tuberculosis_H37Rv PDDLVIGSVFQIHTDK-----GPQYYVVLPDGIAQVNATTAAALRATQAH
MMAR_5444|M.marinum_M PEDLVIGSVFQIHTDK-----GPQYYVVLTDGIAAVNGTTAAALRATQSH
MLBr_00054|M.leprae_Br4923 SPDLVIGSVFQIQMEK-----SPQYYVVLSDGIAQVNATTADALRATQSH
Mflv_0772|M.gilvum_PYR-GCK PPALVIGSVFVTVTDMGEQT-DEQGYVVLPSGVAKVNSTTAAALRATNSY
Mvan_0073|M.vanbaalenii_PYR-1 PPELVVGSVFVTVTDAGEQA-GEQNYVVLPNGVAKVNTTTAAALRATNSF
TH_3503|M.thermoresistible__bu PEHLVIGSVFKTVTDS------EQHYVVLPDGVARVNNTTAAALRARNSY
MSMEG_0060|M.smegmatis_MC2_155 PENLVIGSVFRTATES-----DPQHYVVLPDGVARVNNTTAAALRATNSY
MAV_4870|M.avium_104 P--APIGAVVVSYTLDQSSSGAPRYYAVLPDGLQQISPVLAAILRNTNSY
MUL_1205|M.ulcerans_Agy99 P--GPIGSVVQAYTLGDNS---IQYYAVLPDGLQPISPVLAAIVRNTNSY
MAB_2233c|M.abscessus_ATCC_199 PVAAPIGSVLVSYSTDNTP----VHYAVLTDGVQQISPVIASALRNANSY
. :*:*. *.**..*: :. . * :* ::.
Mb3899|M.bovis_AF2122/97 GLVAPPAMVPSLVVRIAER--VYPSPLPDEPLKIVSRPQDPALCWSWQRS
Rv3869|M.tuberculosis_H37Rv GLVAPPAMVPSLVVRIAER--VYPSPLPDEPLKIVSRPQDPALCWSWQRS
MMAR_5444|M.marinum_M GLVAPPAVVPSLVVRIPER--VYSSPLPDETLNLMSRPDDPVLCWEWERS
MLBr_00054|M.leprae_Br4923 GLVAPPSLVPNVVVQIPER--VYDSPLPDEPLKMVARDDYPTLCWAWERK
Mflv_0772|M.gilvum_PYR-GCK GLIEPPSMESSVVARIPEQ--VYTSPLPDRPMDVLGRQEVPTLCWSWQRV
Mvan_0073|M.vanbaalenii_PYR-1 GLIEPPSLESSAVARIPEQ--VYDSPLPGVPMDVLARQELPTLCWAWQRV
TH_3503|M.thermoresistible__bu GLVMPPTIESSVVARIPEH--VFVSPLPDRPLDMLLREETPTLCWSWQRE
MSMEG_0060|M.smegmatis_MC2_155 GLMQPPAVEASVVAKIPEQ--VYVSPLPDQPLDVLLRQDSPVLCWSWQRE
MAV_4870|M.avium_104 GLDQPPRLGADAVAKLPVSRMLDTARYPDQHVSLVDTAKSPVTCAYWSKP
MUL_1205|M.ulcerans_Agy99 GLQQPPRIGADDVAKLPVSRMLDTTRYPATPMHLVDTESNPITCAYWSKP
MAB_2233c|M.abscessus_ATCC_199 GLEQPPRLTADQIAHLPTSSAIDTRVFPNVAVKPLAADEDPVLCTRFTRT
** ** : .. :.::. : * : : . * * : :
Mb3899|M.bovis_AF2122/97 AGDQSPQSTVLSGRHLPISPSAMNMGIKQIHG------TATVYLDGGKFV
Rv3869|M.tuberculosis_H37Rv AGDQSPQSTVLSGRHLPISPSAMNMGIKQIHG------TATVYLDGGKFV
MMAR_5444|M.marinum_M AGDQAPNTTVLTGRHLPIPPSAMKTGLKQIQG------RSTVYIDGGKFV
MLBr_00054|M.leprae_Br4923 ASDQAPKRTMLIGQHLPLQPSAMSTGIKQIRG------TATVYIDGGRYV
Mflv_0772|M.gilvum_PYR-GCK AGDQAPKMTVIAGRRLPLPPSALATGIDQISG------DATVYVDGGQYI
Mvan_0073|M.vanbaalenii_PYR-1 AGDQAPKMTVIAGRRLPLPPSALSTGIDQITG------DATVYIDGGQYI
TH_3503|M.thermoresistible__bu PGDQAPETTVIAGRRLPIAPSAMNRGIDQIGG------DATVYLAGGQYI
MSMEG_0060|M.smegmatis_MC2_155 PGDQAPKTTVIAGRRLPLPANAIGTGIDQIGG------DSTVYIEGGQFV
MAV_4870|M.avium_104 AGAATSSLNLLSGSALPIAESIRPVDLVGGGSPQNGPVATRVALPPGTGY
MUL_1205|M.ulcerans_Agy99 VGATTSSLTLLSGAALPVPGAVHTVDLVGGGS-QNGAVATRVALAPGTGY
MAB_2233c|M.abscessus_ATCC_199 ADATADSWSLLAGSVLPLSDSVHTVQLISPAA-----TPTRVAIAPGTGY
. : . .:: * **: : . : * : *
Mb3899|M.bovis_AF2122/97 ALQSPD----PRYTESMYYIDPQGVRYGVP---------NAETAKSLGLS
Rv3869|M.tuberculosis_H37Rv ALQSPD----PRYTESMYYIDPQGVRYGVP---------NAETAKSLGLS
MMAR_5444|M.marinum_M QLQSPD----PRYGESMYYIDPEGVRYGVP---------DADSAKALGLG
MLBr_00054|M.leprae_Br4923 ALQSPD----PRYSESLYYVDPEGVRYGLA---------NSEAVKALGLA
Mflv_0772|M.gilvum_PYR-GCK QLQSPE----PRYGENLYYIDPQGVRYGLP---------DQETAARLGLS
Mvan_0073|M.vanbaalenii_PYR-1 RLQSPD----PRFGENLYYIDPQGVRYGLP---------DEETAAKLGLS
TH_3503|M.thermoresistible__bu RLQSPD----PRYGESLYYIDPQGVRYGLP---------DEDTAGYLGLH
MSMEG_0060|M.smegmatis_MC2_155 RLQSPD----PRVGESMYYIDPQGVRYGIA---------NDDAAKNLGLA
MAV_4870|M.avium_104 FTQTASGGAGSPGAGSLFWVSDTGVRYGIDNEAEHSAAGHGKTVEALGLS
MUL_1205|M.ulcerans_Agy99 FTQTAGGGPAAPPTGSLFWVSDTGVRYGIDTEGE----GGRKTVEALGLQ
MAB_2233c|M.abscessus_ATCC_199 LVQPGG-------RGGYQWISDTGVRYGIDTEAE-----GDKTLEALGLH
*. . ::. *****: .: ***
Mb3899|M.bovis_AF2122/97 SP-QNAPWEIVRLLVDGPVLSKDAALLEHDTLPA-DPSPRKVPAGASGAP
Rv3869|M.tuberculosis_H37Rv SP-QNAPWEIVRLLVDGPVLSKDAALLEHDTLPA-DPSPRKVPAGASGAP
MMAR_5444|M.marinum_M MP-KTAPWEIVRLLVDGPVLSKDAALLEHETLPS-DPNPRKVPAGTPGAP
MLBr_00054|M.leprae_Br4923 SP-QTAPWVIVRLLVEGPVLSRDAALLEHDTLIA-DPSPRKVPAGYSGVR
Mflv_0772|M.gilvum_PYR-GCK AP-RTAPWQVVSLLVDGPVLSQQAALIEHDTLPP-NPNPRRAGGGSTA--
Mvan_0073|M.vanbaalenii_PYR-1 SP-RTAPWQVVSLLVDGPVLSQQAALVEHDTLPP-NPNPRSVGADAAAPV
TH_3503|M.thermoresistible__bu GP-ATAPWQVVSLLVDGPVLSKAAALVEHDVLPG-NPHPRKIADGAAA--
MSMEG_0060|M.smegmatis_MC2_155 GP-VNAPWQVVGLLVDGPVLSKEAALIEHDTLPA-DPNPRKVASGEG---
MAV_4870|M.avium_104 GSPLPIPWSVLSLFAKGPTLSRADALLAHDGLPP-DQAPGRVAAAAPQAE
MUL_1205|M.ulcerans_Agy99 DPPVLIPWSVLSLFAPGPTLSRADALMAHDGLAP-DSKPGRPAS----AE
MAB_2233c|M.abscessus_ATCC_199 KPALTIPSSILDLFASGPSLSRADALLARDSLTPTDRQAVPVQTDTQLAQ
. * :: *:. ** **: **: :: * : .
Mb3899|M.bovis_AF2122/97 --------
Rv3869|M.tuberculosis_H37Rv --------
MMAR_5444|M.marinum_M Q-------
MLBr_00054|M.leprae_Br4923 P-------
Mflv_0772|M.gilvum_PYR-GCK QANVGGGG
Mvan_0073|M.vanbaalenii_PYR-1 GANNGGGG
TH_3503|M.thermoresistible__bu -APGPGGG
MSMEG_0060|M.smegmatis_MC2_155 --------
MAV_4870|M.avium_104 GAPR----
MUL_1205|M.ulcerans_Agy99 GGPR----
MAB_2233c|M.abscessus_ATCC_199 NAQESR--