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M. gilvum PYR-GCK Mflv_0496 (-)

annotation: DNA topoisomerase (ATP-hydrolyzing)
coordinates: 521635 - 523668
length: 677

VSYTAADITELDDVQHTRLRPAVNLGLDVLNTALRELIDNAVEEVADPDHGGSVVTITLHADGSVSVADD
GRGLPVDTDPTTGKNGIVKTLGTARAGGKFSAHTDATSTGAGLNGIGAAAAVFISARTDVTVRRGGKTYL
QSFGRGYPGVFEGKEFDPGAPFTRSDTQKLRGVGNRKPDAHGTTVRILFDPAVVPDSAVDIGEVLLRAHA
AARMSPGVQLFVVDEGWPGEEIPPALLEPFKGPWGTDTLLDLMCTAAGTPAPGVRAVVEGRGEYTTGRGP
TPFRWSLTAGPAEPATVAAFCNTVRTPGGGSHLTAAVKGLSEALADRASRIRDLGLAKGEEGPEPQDFAA
VTALAVDTRAPDVAWDSQAKTAVSSRSLNIAMAPDVARSVTVWAANPANSDTVSLWTKLALESARARRSA
EGAKARSRAASKAKGLGTNLSLPPKLLPSRETGRGSGAELFLCEGDSALGTIKAARDATFQAAFPLKGKP
PNVYGFALSKARAKDEFDSIERILGCGVRDNCDPELCRYDRILFASDADPDGGNINSSLISMFLDFYRPL
VEAGMVYVTLPPLFVVKAGDERIYCQDESERDAAVARLKETSKRKVEVQRNKGLGEMDADDFWNTVLDPQ
RRTVIRLHPDDAEKKLHHTLFGGPPEGRRTWMAEIAARVDTASLDLT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0496--100% (677)DNA topoisomerase (ATP-hydrolyzing)
M. gilvum PYR-GCKMflv_0822gyrB2e-5728.65% (705) DNA gyrase subunit B

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0005gyrB5e-6029.40% (704) DNA gyrase subunit B
M. tuberculosis H37RvRv0005gyrB1e-5929.26% (704) DNA gyrase subunit B
M. leprae Br4923MLBr_00005gyrB1e-6228.47% (706) DNA gyrase subunit B
M. abscessus ATCC 19977MAB_0006gyrB3e-5828.04% (699) DNA gyrase subunit B
M. marinum MMMAR_0005gyrB6e-6228.82% (701) DNA gyrase (subunit B) GyrB
M. avium 104MAV_0005gyrB2e-5827.98% (704) DNA gyrase subunit B
M. smegmatis MC2 155MSMEG_0457-0.092.17% (677) DNA topoisomerase IV subunit B
M. thermoresistible (build 8)TH_0757gyrB8e-6329.73% (703) DNA GYRASE (SUBUNIT B) GYRB (DNA TOPOISOMERASE
M. ulcerans Agy99MUL_0005gyrB2e-6128.67% (701) DNA gyrase subunit B
M. vanbaalenii PYR-1Mvan_5897-0.093.35% (677) DNA topoisomerase (ATP-hydrolyzing)

CLUSTAL 2.0.9 multiple sequence alignment


Mb0005|M.bovis_AF2122/97            MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDE
Rv0005|M.tuberculosis_H37Rv         MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDE
MAB_0006|M.abscessus_ATCC_1997      ---------------------------------------MAAQKKSAKSE
MMAR_0005|M.marinum_M               ------------------------MTGPRASNPEENIRTVAAQKKKAQDE
MUL_0005|M.ulcerans_Agy99           ------------------------MTGPRASNPEENIRTVAAQKKKAQDE
MAV_0005|M.avium_104                ---------------------------------------MAAQKKKAQDE
MLBr_00005|M.leprae_Br4923          ---------------------------------------MAAQR-KAQDE
TH_0757|M.thermoresistible__bu      ---------------------------------------VAAQKKKKQED
Mflv_0496|M.gilvum_PYR-GCK          ------------------------------------------------MS
Mvan_5897|M.vanbaalenii_PYR-1       ------------------------------------------------MS
MSMEG_0457|M.smegmatis_MC2_155      ------------------------------------------------MS
                                                                                     .

Mb0005|M.bovis_AF2122/97            YGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAG-
Rv0005|M.tuberculosis_H37Rv         YGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAG-
MAB_0006|M.abscessus_ATCC_1997      YSADSITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNSVDEAMAG-
MMAR_0005|M.marinum_M               YGASAITVLEGLEAVRKRPGMYIGSTGERGLHHLVWEVVDNSVDEAMAG-
MUL_0005|M.ulcerans_Agy99           YGASAITVLEGLEAVRKRPGMYIGSTGERGLHHLVWEVVDNSVDEAMAG-
MAV_0005|M.avium_104                YGASAITVLEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNSVDEAMAG-
MLBr_00005|M.leprae_Br4923          YGAASITILEGLEAVRKRPGMYVGSTGERGLHHLIWEVVDNSVDEAMAG-
TH_0757|M.thermoresistible__bu      YGAQSITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAG-
Mflv_0496|M.gilvum_PYR-GCK          YTAADITELDDVQHTRLRPAVNLG---LDVLNTALRELIDNAVEEVADPD
Mvan_5897|M.vanbaalenii_PYR-1       YNAADITELDDVQHTRLRPAVNLG---LDVLNTALRELVDNAIEEVADPS
MSMEG_0457|M.smegmatis_MC2_155      YTAADITELDDVQHTRLRPAVNLG---LDVLNTALREIVDNAIEEVADPG
                                    * *  ** *:.:: .* **.: :*      *:  : *::**:::*.    

Mb0005|M.bovis_AF2122/97            -YATTVNVVLLEDGGVEVADDGRGIPVATH-ASGIPTVDVVMTQLHAGGK
Rv0005|M.tuberculosis_H37Rv         -YATTVNVVLLEDGGVEVADDGRGIPVATH-ASGIPTVDVVMTQLHAGGK
MAB_0006|M.abscessus_ATCC_1997      -YATTVEVTMLADGGIQVKDDGRGIPVAMH-ASGIPTVDVVMTQLHAGGK
MMAR_0005|M.marinum_M               -YATQVNVRLLDDGSVEVADNGRGIPVAMH-ATGAPTVDVVMTQLHAGGK
MUL_0005|M.ulcerans_Agy99           -YATQVNVRLLDDGSVEVADNGRGIPVAMH-ATGAPTVDVVMTQLHAGGK
MAV_0005|M.avium_104                -YADRVDVRILDDGSVEVADNGRGIPVAMH-ATGAPTVDVVMTQLHAGGK
MLBr_00005|M.leprae_Br4923          -YATQVDVRLFDDGSVEVADNGRGIPVAVH-ATGVPTVDVVMTQLHAGGK
TH_0757|M.thermoresistible__bu      -HATKVRVRLLADGGVEVSDDGRGIPVEMH-ESGVPTVDVVMTQLHAGGK
Mflv_0496|M.gilvum_PYR-GCK          HGGSVVTITLHADGSVSVADDGRGLPVDTDPTTGKNGIVKTLGTARAGGK
Mvan_5897|M.vanbaalenii_PYR-1       HGGSTVTITLHADGSVSVADDGRGLPVDSDPVTGKNGIVKTLGTARAGGK
MSMEG_0457|M.smegmatis_MC2_155      HGGSTVTITLHADGSVSVADDGRGLPVDTDPTTGKNGIVKTLGTARAGGK
                                      .  * : :  **.:.* *:***:**  .  :*   :  .:   :****

Mb0005|M.bovis_AF2122/97            FDSD--AYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPL
Rv0005|M.tuberculosis_H37Rv         FDSD--AYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPL
MAB_0006|M.abscessus_ATCC_1997      FDSD--SYAVSGGLHGVGISVVNALSTKLEVEILRDGFEWQQVYTRSEPG
MMAR_0005|M.marinum_M               FGGENSGYNVSGGLHGVGVSVVNALSTRLEVDIKRDGYEWSQFYDRAQPG
MUL_0005|M.ulcerans_Agy99           FGGENSGYNVSGGLHGVGVSVVNALSTRLEVDIKRDGYEWSQFYDRAQPG
MAV_0005|M.avium_104                FGGENSGYNVSGGLHGVGVSVVNALSTRLEVNIARDGYEWSQYYDHAVPG
MLBr_00005|M.leprae_Br4923          FGGKDSGYNVSGGLHGVGVSVVNALSTRVEVDIKRDGYEWSQFYDKAVPG
TH_0757|M.thermoresistible__bu      FDSD--AYAVSGGLHGVGVSVVNALSTRMEVEICRDGYQWFQTYDKSVPG
Mflv_0496|M.gilvum_PYR-GCK          FSAHTDATSTGAGLNGIGAAAAVFISARTDVTVRRGGKTYLQSFGRGYPG
Mvan_5897|M.vanbaalenii_PYR-1       FSAHTDAASTGAGLNGIGAAAAVFISARTDVTVRRAGKTYLQSFGGGYPG
MSMEG_0457|M.smegmatis_MC2_155      FSAHKDATSTGAGLNGIGAAAAVFISARTDVTVRRDGKTFLQSFGRGYPG
                                    *...  .   ..**:*:* :..  :*:: :* : * *  : * :  . * 

Mb0005|M.bovis_AF2122/97            GLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTI
Rv0005|M.tuberculosis_H37Rv         GLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTI
MAB_0006|M.abscessus_ATCC_1997      TLQKGAATKKTGTTVRFWADPEIFETTTYDFETVARRLQEQAFLNKGLTI
MMAR_0005|M.marinum_M               TLKQGEATKKTGTTIRFWADPDIFETTEYDFETVARRLQEMAFLNKGLTI
MUL_0005|M.ulcerans_Agy99           TLKQGEATKKTGTAIRFWADPDIFETTEYDFETVARRLQEMAFLNKGLTI
MAV_0005|M.avium_104                TLKQGEATKRTGTTIRFWADPDIFETTEYDFETVARRLQEMAFLNKGLTI
MLBr_00005|M.leprae_Br4923          ILKQGEATEATGTTIRFWADPDIFETTKYDFGTVARRIQEVAFLNKGLTI
TH_0757|M.thermoresistible__bu      TLKQGEKTRKTGTVVRFWPDPDVFETTTFDFETVARRLQEQAFLNKGLTI
Mflv_0496|M.gilvum_PYR-GCK          VFEGKEFDPGAPFTRSDTQKLRGVGNRKPDAHGTTVRILFDPAVVPDSAV
Mvan_5897|M.vanbaalenii_PYR-1       VFEGRDFDPNAPFTRADTQKLRGSGNRKPDAHGTTVRILFDAAVVPDSTI
MSMEG_0457|M.smegmatis_MC2_155      VFEGKEFDPEAPFTRNDTQKLRGVSNRKPDLHGTEVRILFDPAIAPDSTL
                                     ::       :  .     .     .   *   .  *:   . :  . ::

Mb0005|M.bovis_AF2122/97            NLTDERVTQDEVVDEVVSDVAEAP---KSASERAAESTAPHKVKSRTFHY
Rv0005|M.tuberculosis_H37Rv         NLTDERVTQDEVVDEVVSDVAEAP---KSASERAAESTAPHKVKSRTFHY
MAB_0006|M.abscessus_ATCC_1997      KLTDERVSDSEVTDEVVSDTAEAP---KNAEEQAAESSAPHKVKNRVFHY
MMAR_0005|M.marinum_M               NLTDERVTPDEVVDDVVSDTAEAP---KSAQEKAAESTAPHKVKSRTFHY
MUL_0005|M.ulcerans_Agy99           NLTDERVTPDEVVDDVVSDTAEAP---KSAQEKAAESTAPHKVKSRTFHY
MAV_0005|M.avium_104                NLTDERVTNEEVVDEVVSDTADAP---KSAQEKAAESAAPHKVKHRTFHY
MLBr_00005|M.leprae_Br4923          NLVDERVKQDEVVDDVVSDTAEAPVA-MTVEEKSTESSAPHKVRHRTFHY
TH_0757|M.thermoresistible__bu      ELIDERVTAEEVVDEVVSDVAEAP---KSAEEEAAAANT-QKVKHRTFYY
Mflv_0496|M.gilvum_PYR-GCK          DIGEVLLRAHAAARMSPGVQLFVVDEGWPGEEIPPALLEPFKGPWGTDTL
Mvan_5897|M.vanbaalenii_PYR-1       DVGEVLLRAHAAARMSPGVHLVVVDEGWPGEEIPPALLEPFSGPWGTDTL
MSMEG_0457|M.smegmatis_MC2_155      DIGEVLLRAHAAARMSPGVHLVVVDEGWPGEEVPPAVLEPFSGPWGTDTL
                                    .: :  :    ..    .    .       .* ..      .    .   

Mb0005|M.bovis_AF2122/97            PGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHT
Rv0005|M.tuberculosis_H37Rv         PGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHT
MAB_0006|M.abscessus_ATCC_1997      PDGLVDFVKHINRTKSAIHTTIVDFSGKGEGHEVEIAMQWNAGYSESVHT
MMAR_0005|M.marinum_M               PGGLVDFVKHINRTKSPIQQSIVDFEGKGSGHEVEIAMQWNGGYSESVHT
MUL_0005|M.ulcerans_Agy99           PGGLVDFVKHINRTKSPIQQSIVDFEGKGSGHEVEIAMQWNGGYSESVHT
MAV_0005|M.avium_104                PGGLVDFVKHINRTKNPIHQSIIDFGGKGPGHEVEIAMQWNGGYSESVHT
MLBr_00005|M.leprae_Br4923          PGGLVDFVKHINRTKTPIQQSIIDFDGKGAGHEVEVAMQWNGGYSESVHT
TH_0757|M.thermoresistible__bu      PGGLVDFVKHINRTKSPIHPSIIDFSGKGTGHELEVAMQWNAGYSESVHT
Mflv_0496|M.gilvum_PYR-GCK          LDLMCTAAGTPAPGVRAVVEGRGEYTTGRGPTPFRWSLTAGPAEPATVAA
Mvan_5897|M.vanbaalenii_PYR-1       LDLMCTAAGTPLPGVRAVVEGRGEYTTGRGPTPFRWSLTAGPAEPATVAA
MSMEG_0457|M.smegmatis_MC2_155      LDLMCTAAGTPLPEVRAVVEGRGEYTTGRGPTPFRWSLTAGPAEPATVAA
                                     . :   .        .:     ::        .. ::  . . . :* :

Mb0005|M.bovis_AF2122/97            FANTINTHEGGTHEEGFRSALTSVVNKYAK--DRKLLKDKDPNLTGDDIR
Rv0005|M.tuberculosis_H37Rv         FANTINTHEGGTHEEGFRSALTSVVNKYAK--DRKLLKDKDPNLTGDDIR
MAB_0006|M.abscessus_ATCC_1997      FANTINTHEGGTHEEGFRAALTSVVNKYAK--EKKLLKEKDSNLTGDDIR
MMAR_0005|M.marinum_M               FANTINTHEGGTHEEGFRSALTSVVNKYAK--DKKLLKDKDPNLTGDDIR
MUL_0005|M.ulcerans_Agy99           FANTINTHEGGTHEEGFRSALTSVVNKYAK--DKKLLKDKDPNLTGDDIR
MAV_0005|M.avium_104                FANTINTHEGGTHEEGFRSALTSVVNKYAK--DKKLLKDKDPNLTGDDIR
MLBr_00005|M.leprae_Br4923          FANTINTHEGGTHEEGFRSALTSVVNKYAK--DKKLLKDKDPNLTGDDIR
TH_0757|M.thermoresistible__bu      FANTINTHEGGTHEEGFRAALTSVVNRYAK--DKKLLKDKDPNLTGDDIR
Mflv_0496|M.gilvum_PYR-GCK          FCNTVRTPGGGSHLTAAVKGLSEALADRASRIRDLGLAKGEEGPEPQDFA
Mvan_5897|M.vanbaalenii_PYR-1       FCNTVRTPGGGSHLTAAVKGLSEALADRASRIRDLGLAKGEDGPEPQDFA
MSMEG_0457|M.smegmatis_MC2_155      FCNTVRTPGGGSHLTAAIKGLSEALAERASRMRDLGLAKNEEGPEPQDFA
                                    *.**:.*  **:*  .   .*:..:   *.      * . : .   :*: 

Mb0005|M.bovis_AF2122/97            EGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFE--AN
Rv0005|M.tuberculosis_H37Rv         EGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFE--AN
MAB_0006|M.abscessus_ATCC_1997      EGLAAVISVKVGEPQFEGQTKTKLGNTEVKSFVQKVCNEQLQHWFD--SN
MMAR_0005|M.marinum_M               EGLAAVISVRVAEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFE--AN
MUL_0005|M.ulcerans_Agy99           EGLAAVISVRVAEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFE--AN
MAV_0005|M.avium_104                EGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFE--AN
MLBr_00005|M.leprae_Br4923          EGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQRVCNEQLIHWFE--AN
TH_0757|M.thermoresistible__bu      EGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKTCNEQLSHWFE--AN
Mflv_0496|M.gilvum_PYR-GCK          AVTALAVDTRAPDVAWDSQAKTAVSSRSLNIAMAPDVARSVTVWAANPAN
Mvan_5897|M.vanbaalenii_PYR-1       AVTALAVDTRAPDVAWDSQAKTAVSSRSLNLAMAPDVARSVTIWAANPAN
MSMEG_0457|M.smegmatis_MC2_155      AVTALAVDTRAPDVAWDSQAKTAVSSRSLNLAMAPDVARSVTIWAANPAN
                                       * .:..:. :  ::.*:** :.. .::  :     ..:  *    :*

Mb0005|M.bovis_AF2122/97            PTDSKVVVNKAVSSAQARIAARKARELVRRKSATDIGG----LPGKLADC
Rv0005|M.tuberculosis_H37Rv         PTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGG----LPGKLADC
MAB_0006|M.abscessus_ATCC_1997      PADAKTVVNKAVSSAQARIAARKARELVRRKSATDIGG----LPGKLADC
MMAR_0005|M.marinum_M               PSEAKTIVNKAVSSAQARLAARKARELVRRKSATDLGG----LPGKLADC
MUL_0005|M.ulcerans_Agy99           PSEAKTIVNKAVSSAQARLAARKARELVRRKSATDLGG----LPGKLADC
MAV_0005|M.avium_104                PADAKVIVNKAVSSAQARIAARKARELVRRKSATDLGG----LPGKLADC
MLBr_00005|M.leprae_Br4923          PVDAKAVVNKAISSAQARIAARKARELVRRKSATDLGG----LPGKLADC
TH_0757|M.thermoresistible__bu      PAEAKIIVNKAISSAQARIAARKARELVRRKSATDIGG----LPGKLADC
Mflv_0496|M.gilvum_PYR-GCK          SDTVSLWTKLALESARARRSAEGAKARSRAASKAKGLGTNLSLPPKLLPS
Mvan_5897|M.vanbaalenii_PYR-1       NDAVSLWTKLALEAARARRSAEGAKARSRAASKAKGLGTNLSLPPKLLPS
MSMEG_0457|M.smegmatis_MC2_155      ADTVTLWSKLALESARARRSAEGAKARARAASKAKGLGTNLSLPPKLLPS
                                        .   : *:.:*:** :*. *:   *  * :.  *    ** **  .

Mb0005|M.bovis_AF2122/97            RSTDPRK-SELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARID
Rv0005|M.tuberculosis_H37Rv         RSTDPRK-SELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARID
MAB_0006|M.abscessus_ATCC_1997      RSTDPSK-SELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARID
MMAR_0005|M.marinum_M               RSTDPRK-SELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARID
MUL_0005|M.ulcerans_Agy99           RSTDPRK-SELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARID
MAV_0005|M.avium_104                RSTDPRK-SELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARID
MLBr_00005|M.leprae_Br4923          RSTDPRS-SELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARID
TH_0757|M.thermoresistible__bu      RSTDPTV-SELYIVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARID
Mflv_0496|M.gilvum_PYR-GCK          RETGRGSGAELFLCEGDSALGTIKAARDATFQAAFPLKGKPPNVYGFALS
Mvan_5897|M.vanbaalenii_PYR-1       RETGRGSGAELFLCEGDSALGTIKAARDATFQAAFPLKGKPPNVYGFALS
MSMEG_0457|M.smegmatis_MC2_155      RESGRGSGAELFLCEGDSALGTIKAARDATFQAAFPLKGKPPNVYGFPLN
                                    *.:.    :**:: ***** *: *:.**: *** :**:**  **    :.

Mb0005|M.bovis_AF2122/97            RVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLL
Rv0005|M.tuberculosis_H37Rv         RVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLL
MAB_0006|M.abscessus_ATCC_1997      RVLKNTEVQAIITALGTGIHDEFDIAKLRYHKIVLMADADVDGQHISTLL
MMAR_0005|M.marinum_M               RVLKNTEVQAIITALGTGIHDEFDLSKLRYHKIVLMADADVDGQHISTLL
MUL_0005|M.ulcerans_Agy99           RVLKNTEVQAIITALGTGIHDEFDLSKLRYHKIVLMADADVDGQHISTLL
MAV_0005|M.avium_104                RVLKNTEVQAIITALGTGIHDEFDITKLRYHKIVLMADADVDGQHISTLL
MLBr_00005|M.leprae_Br4923          RVLKNTEVQAIITALGTGIHDEFDISRLRYHKIVLMADADVDGQHISTLL
TH_0757|M.thermoresistible__bu      RVLKNTEVQAIITALGTGIHDEFDISKLRYHKIILMADADVDGQHIATLL
Mflv_0496|M.gilvum_PYR-GCK          KARAKDEFDSIERILGCGVRDNCDPELCRYDRILFASDADPDGGNINSSL
Mvan_5897|M.vanbaalenii_PYR-1       KARVKDEFDSIERILGCGVRDHCDPELCRYDRILFASDADPDGGNINSSL
MSMEG_0457|M.smegmatis_MC2_155      KARAKDEFDAIERILGCGVRDHCDPELCRYDRILFASDADPDGGNINSSL
                                    :.  : *.::*   ** *::*. *    **.:*:: :*** ** :* : *

Mb0005|M.bovis_AF2122/97            LTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAG
Rv0005|M.tuberculosis_H37Rv         LTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAG
MAB_0006|M.abscessus_ATCC_1997      LTLLFRFMRPLVEHGHIFLAQPPLYKLKWQRTQPEFAYSDRERDGLMEAG
MMAR_0005|M.marinum_M               LTLLFRFMRPLIENGHVFLAQPPLYKLKWQRTEPEFAYSDRERDGLLEAG
MUL_0005|M.ulcerans_Agy99           LTLLFRFMRPLIENGHVFLAQPPLYKLKWQRTEPEFAYSDRERDGLLEAG
MAV_0005|M.avium_104                LTLLFRFMRPLIEHGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAG
MLBr_00005|M.leprae_Br4923          LTLLFRFMRPLIEHGYVFLAQPPLYKLKWQRMDPEFAYSDSERDGLLETG
TH_0757|M.thermoresistible__bu      LTLLFRFMKPLIENGHVYLAQPPLYKLKWQRSEPEFAYSDRERDALLEAG
Mflv_0496|M.gilvum_PYR-GCK          ISMFLDFYRPLVEAGMVYVTLPPLFVVKAG-DERIYCQDESERD---AAV
Mvan_5897|M.vanbaalenii_PYR-1       ISMFLDFYRPLVEAGMVYVTLPPLFVVKNG-DERIYCQDESERD---AAV
MSMEG_0457|M.smegmatis_MC2_155      ISMFLDFYRPLVEAGMVYVTMPPLFVVKAG-DERIYCQDESERD---AAV
                                    ::::: * :**:* * :::: ***: :*    :  :. .: ***    : 

Mb0005|M.bovis_AF2122/97            LKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAA
Rv0005|M.tuberculosis_H37Rv         LKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAA
MAB_0006|M.abscessus_ATCC_1997      LKAGKKINKDDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAA
MMAR_0005|M.marinum_M               LKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAA
MUL_0005|M.ulcerans_Agy99           LKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAA
MAV_0005|M.avium_104                LKAGKKINKDDGIQRYKGLGEMDAKELWETTMDPTVRVLRQVTLDDAAAA
MLBr_00005|M.leprae_Br4923          LKLGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAA
TH_0757|M.thermoresistible__bu      LKAGKKINKDDGIQRYKGLGEMDAKELWETTMDPSTRILRQVTLDDAAAA
Mflv_0496|M.gilvum_PYR-GCK          ARLKETSKRKVEVQRNKGLGEMDADDFWNTVLDPQRRTVIRLHPDDAEKK
Mvan_5897|M.vanbaalenii_PYR-1       AQLKATSKKRVEVQRNKGLGEMDADDFWTTVLDPQRRTVIRVHPDDGEKK
MSMEG_0457|M.smegmatis_MC2_155      AQLKASSNRRVEVQRNKGLGEMDADDFWNTVLDPQRRTVIRVRPDESEKK
                                     :   . ::   :** ********.::* *.:**  * : ::  *:.   

Mb0005|M.bovis_AF2122/97            DELFSILMGEDVDARRSFITRNAKDVRFLDV---
Rv0005|M.tuberculosis_H37Rv         DELFSILMGEDVDARRSFITRNAKDVRFLDV---
MAB_0006|M.abscessus_ATCC_1997      DELFSILMGEDVEARRSFITRNAKDVRFLDV---
MMAR_0005|M.marinum_M               DELFSILMGEDVDARRSFITRNAKDVRFLDV---
MUL_0005|M.ulcerans_Agy99           DELFSILMGEDVDARRSFITRNAKDVRFLDV---
MAV_0005|M.avium_104                DELFSILMGEDVDARRSFITRNAKDVRFLDV---
MLBr_00005|M.leprae_Br4923          DELFSILMGEDVDARRSFITRNAKDVRFLDV---
TH_0757|M.thermoresistible__bu      DELFSILMGEDVEARRSFITRNAKDVRFLDV---
Mflv_0496|M.gilvum_PYR-GCK          --LHHTLFGGPPEGRRTWMAEIAARVDTASLDLT
Mvan_5897|M.vanbaalenii_PYR-1       --LHHTLFGGPPEGRRTWMADVASRIDTSALDLT
MSMEG_0457|M.smegmatis_MC2_155      --LHHTLFGGPPEGRRTWMADVAARVDTSALDLT
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