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MPSGVAVGWPVKREFFDLVCGGMPTTEASLAVGVSRRTGWFWWRQAGGMTLRKGGEGLGGLADAGDLERP GGRGHRLSFAERFEIDRGLQAGRSYAEIGRELGRDRSVIAREVKRNCLPDGRYHALMAHAAASQKARRPK KFKLDNPALCALIAGWMDEGWSPKLISQVLAETYAGDKLMQVSHETIYQCLYVQTRGQLRADLHKCLSTK RRARSPRGHRGRTGVYDPDTIFTISDRPAEANDRAVPGHWEGDLILGARHGSAIGTLVERSTRFVILLHL PVDHTAQSVAAAMIEAMGELPAHLRRSITWDRGSEMASWKHVQMQLNSPVFFCDPHSPWQRGTNENTNRL LRFWFEKGSDLSVHTRDDLNTVAAKLNSRPRPTLDLDTPAQRMAALLSQAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0481 | - | - | 100% (401) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_0382 | - | 0.0 | 97.26% (401) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3213c | - | 4e-65 | 43.29% (328) | transposase |
| M. tuberculosis H37Rv | Rv3191c | - | 4e-65 | 43.29% (328) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2675 | - | 9e-65 | 37.69% (451) | ISMsm8, transposase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4654 | - | 1e-177 | 76.31% (401) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3213c|M.bovis_AF2122/97 --------------------------------------------------
Rv3191c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0481|M.gilvum_PYR-GCK ------------------MPSGVAVGWPVKRE-FFDLVCGGMPTTEASLA
Mvan_4654|M.vanbaalenii_PYR-1 ------------------MPSGVPVPLSVKRV-FFDLVCGGMTTTEASVQ
MSMEG_2675|M.smegmatis_MC2_155 MGVLDRQRAVRLYRGQIPSPGRPSVAWRQDRVRFWAAIAAGAMTEDAAAE
Mb3213c|M.bovis_AF2122/97 -----------------------------------MRQISSR--YLSEEE
Rv3191c|M.tuberculosis_H37Rv -----------------------------------MRQISSR--YLSEEE
Mflv_0481|M.gilvum_PYR-GCK VGVSRRTGWFWWRQAGGMTLRKGGEGLGGLADAGDLERPGGRGHRLSFAE
Mvan_4654|M.vanbaalenii_PYR-1 VGVSRRTGWSWWRHARGMKLRKGGDGLGGLAQVGDLTRTGGRGHRLSFTE
MSMEG_2675|M.smegmatis_MC2_155 AGVSSPVGFRWFRHAGGVN-------------PCLPETVSGR--YLSSDE
..* ** *
Mb3213c|M.bovis_AF2122/97 RINIADLRRSGLSIRKIADQLGRAPSTVSRELRRNSRRDGQ---YRPFEA
Rv3191c|M.tuberculosis_H37Rv RINIADLRRSGLSIRKIADQLGRAPSTVSRELRRNSRRDGQ---YRPFEA
Mflv_0481|M.gilvum_PYR-GCK RFEIDRGLQAGRSYAEIGRELGRDRSVIAREVKRNCLPDGR---YHALMA
Mvan_4654|M.vanbaalenii_PYR-1 RYEIDRALQAGLSYAAIGDQLGRDRSVIWREVQRNRLPDGT---YHALMA
MSMEG_2675|M.smegmatis_MC2_155 RENIALWRAQGAGVREIARRLKRAPSTISRELRRNASTRTYRLDYKASTA
* :* * . *. .* * *.: **::** *:. *
Mb3213c|M.bovis_AF2122/97 HRWAVQRRVRRHRRRIDKNPDLCELIAELLA-------------------
Rv3191c|M.tuberculosis_H37Rv HRWAVQRRVRRHRRRIDKNPDLCELIAELLA-------------------
Mflv_0481|M.gilvum_PYR-GCK HAAASQKARRPKKFKLD-NPALCALIAGWMD-------------------
Mvan_4654|M.vanbaalenii_PYR-1 HARATENARRPKAFKLD-DPGLCADIEAWMD-------------------
MSMEG_2675|M.smegmatis_MC2_155 QWHAERRARRPKTAKLVSNDRLRQYVQDKLSGVVRGADGQVIVGPAAAPW
: * .. * : :: : * : :
Mb3213c|M.bovis_AF2122/97 --------------QRWSPQQIARHLRRKYPDDRSMWLCHESIYQAVYQP
Rv3191c|M.tuberculosis_H37Rv --------------QRWSPQQIARHLRRKYPDDRSMWLCHESIYQAVYQP
Mflv_0481|M.gilvum_PYR-GCK --------------EGWSPKLISQVLAETYAGDKLMQVSHETIYQCLYVQ
Mvan_4654|M.vanbaalenii_PYR-1 --------------QGWSPKLISQVLARDAGSAKVKRVSHETIYQSLYVQ
MSMEG_2675|M.smegmatis_MC2_155 KGRNKPHRGDRAWVQAWSPEQIARRLPLDFPDDVTMRISHEAIYQALYVE
: ***: *:: * . :.**:***.:*
Mb3213c|M.bovis_AF2122/97 QSRLIRPPQVKSPHRGPLRTGRTHRRAHLRPGRRRPRFAQPMLSIHQRPF
Rv3191c|M.tuberculosis_H37Rv QSRLIRPPQVKSPHRGPLRTGRTHRRAHLRPGRRRPRFAQPMLSIHQRPF
Mflv_0481|M.gilvum_PYR-GCK TRGQLRADLHKC-----LSTKRRARSPRGHRGRTGVYDPDTIFTISDRPA
Mvan_4654|M.vanbaalenii_PYR-1 TRGQLRADLHKC-----LSTSRTQRKPRGQTERRGRFG--DVMRISARPA
MSMEG_2675|M.smegmatis_MC2_155 SRGALKRDLVSC-----LRRGRALRVPRARTRSKAWAHVTPETLISQRPP
:: .. * * * .: : * **
Mb3213c|M.bovis_AF2122/97 DPADRSEPGHWEGDLIVGKNQGSAIGTLVERQTRLIRLLHLP--------
Rv3191c|M.tuberculosis_H37Rv DPADRSEPGHWEGDLIVGKNQGSAIGTLVERQTRLIRLLHLP--------
Mflv_0481|M.gilvum_PYR-GCK EANDRAVPGHWEGDLILGARHGSAIGTLVERSTRFVILLHLPV-------
Mvan_4654|M.vanbaalenii_PYR-1 EAADRAVPGHWEGDLIIGARGGSAIGTLVERSTRFTILLHLPG-------
MSMEG_2675|M.smegmatis_MC2_155 EVDDRAVPGHWEGDLLIGLQR-SAIGTLVERSSRFTMLVHLPREVGYGII
: **: ********::* . *********.:*: *:***
Mb3213c|M.bovis_AF2122/97 ----------THDAYCLRIAITETMSDLPVTLVRSITWDQGIEMARHIDI
Rv3191c|M.tuberculosis_H37Rv ----------THDAYCLRIAITETMSDLPVTLVRSITWDQGIEMARHIDI
Mflv_0481|M.gilvum_PYR-GCK ----------DHTAQSVAAAMIEAMGELPAHLRRSITWDRGSEMASWKHV
Mvan_4654|M.vanbaalenii_PYR-1 ----------DHTAETVAAAMLKAMGDLPDHLRRSITWDRGSEMAGWQDI
MSMEG_2675|M.smegmatis_MC2_155 PRTKNGPALAGYGAITMANALEQTITTLPAQLRRSLTWDRGKELSAHAQF
: * : *: ::: ** * **:***:* *:: ..
Mb3213c|M.bovis_AF2122/97 TADLGAPVYFCDSRSPWQRASNENSNGLLRQYFPKGTSLSTYTPDHLRAV
Rv3191c|M.tuberculosis_H37Rv TADLGAPVYFCDSRSPWQRASNENSNGLLRQYFPKGTSLSTYTPDHLRAV
Mflv_0481|M.gilvum_PYR-GCK QMQLNSPVFFCDPHSPWQRGTNENTNRLLRFWFEKGSDLSVHTRDDLNTV
Mvan_4654|M.vanbaalenii_PYR-1 SLQLQSPVYFCDPHSPWQRGTNENTNRLLRFWFEKGTDLSGYTPDDLKAV
MSMEG_2675|M.smegmatis_MC2_155 SVASGVKVFFADPKSPWQRGTNENTNGLLRQYFPKGTDLSRWSAEDVAAI
*:*.*.:*****.:***:* *** :* **:.** : :.: ::
Mb3213c|M.bovis_AF2122/97 EYEINNRPRQVLGHRSPAELFTALLTSPDHQLLRR--
Rv3191c|M.tuberculosis_H37Rv EYEINNRPRQVLGHRSPAELFTALLTSPDHQLLRR--
Mflv_0481|M.gilvum_PYR-GCK AAKLNSRPRPTLDLDTPAQRMAALLSQAA--------
Mvan_4654|M.vanbaalenii_PYR-1 ADKLNTRPRPTLDLDTPAQRMAQLLSQAA--------
MSMEG_2675|M.smegmatis_MC2_155 AHTLNTRPRKTLGWRTPAEAFAEHLHSLHQAGVATTD
:*.*** .*. :**: :: * .