For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PTLPMFPLEVAMLPGEELPLRIFEPRYSALVRACLAAEDPVFGVVLIAAGREVGGGDARSDVGALARITE HSDLGAGRYRLKCVMAERIRVLEWLPDDPYPRAVMQEWPDEPGGPVDFAAIRDIEDRMVGLFERIATARG AQVNARDIVHGADDSGDPAQWLYALTARLPMGQADRYAILAAPSVADRVAALSEAVDTVIAMVEFQLSE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0170 | - | - | 100% (210) | peptidase S16, lon domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0442 | - | 6e-72 | 63.46% (208) | hypothetical protein Mb0442 |
| M. tuberculosis H37Rv | Rv0434 | - | 2e-71 | 62.98% (208) | hypothetical protein Rv0434 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4165 | - | 4e-56 | 54.11% (207) | hypothetical protein MAB_4165 |
| M. marinum M | MMAR_0751 | - | 7e-73 | 66.51% (209) | hypothetical protein MMAR_0751 |
| M. avium 104 | MAV_4720 | - | 1e-67 | 62.50% (208) | ATP-dependent protease La |
| M. smegmatis MC2 155 | MSMEG_0839 | - | 4e-74 | 66.19% (210) | ATP-dependent protease La |
| M. thermoresistible (build 8) | TH_0947 | - | 1e-76 | 66.82% (211) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1383 | - | 1e-71 | 65.55% (209) | hypothetical protein MUL_1383 |
| M. vanbaalenii PYR-1 | Mvan_0737 | - | 2e-99 | 83.81% (210) | peptidase S16, lon domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0442|M.bovis_AF2122/97 -MADFAPVELAMFPLESAPLPDEDLPLHIFEPRYAALVRDCMDTADPRFG
Rv0434|M.tuberculosis_H37Rv -MADFAPVELAMFPLESAPLPDEDLPLHIFEPRYAALVRDCMDTADPRFG
MMAR_0751|M.marinum_M MVAVPKPFEAPMFPLEAAMLPGQDLPLRIFEPRYSALVRHCLDTGDP-FG
MUL_1383|M.ulcerans_Agy99 MVAVPKPFEAPMFPLEATMLPGQDLPLRIFEPRDSALVRHCLDTGDP-FG
MAV_4720|M.avium_104 ---MTEPVALPMFPLESALLPDQDLPLRIFEPRYGALVRHCLDTGEQ-FG
Mflv_0170|M.gilvum_PYR-GCK ------MPTLPMFPLEVAMLPGEELPLRIFEPRYSALVRACLAAEDPVFG
Mvan_0737|M.vanbaalenii_PYR-1 ------MPTVPMFPLEVAMLPGEELPLRIFEPRYSALVQACLAAEDPAFG
MSMEG_0839|M.smegmatis_MC2_155 ------MTVTPMFPLEVAMLPGEELPLRIFEPRYQALVSDCMAMPEPAFG
TH_0947|M.thermoresistible__bu ------MTITPMFPLEIAMLPGEELPLRIFEPRYRELVQTCLAAEVPAFG
MAB_4165|M.abscessus_ATCC_1997 --------MTPMFPLQSVLLPGEPLPLRIFEPRYVAMIRDVLAADHT-FG
.****: . **.: ***:***** :: : **
Mb0442|M.bovis_AF2122/97 VVLISRGREVGGGDTRCDVGTLARITECADAGSGRYMLRCRVGERIRVCD
Rv0434|M.tuberculosis_H37Rv VVLISRGREVGGGDTRCDVGTLARITECADAGSGRYMLRCRVGERIRVCD
MMAR_0751|M.marinum_M VVLIAGGREVGGGESRYDVGTLARITEYVDEGAGRYQLLCRTGERIRVCD
MUL_1383|M.ulcerans_Agy99 VVLIAGGREVGGGESRYDVGTLARITEYVDEGAGRYQLLCRTGERIRVCD
MAV_4720|M.avium_104 VVLIARGREVGGGDARCDVGVLSRIVDCVDQGAGRYLLNCRTGQRIRVSE
Mflv_0170|M.gilvum_PYR-GCK VVLIAAGREVGGGDARSDVGALARITEHSDLGAGRYRLKCVMAERIRVLE
Mvan_0737|M.vanbaalenii_PYR-1 VVLIAAGREVGGGDTRSDIGALAHIAECVDMGSGRYRLKCVIGERIRVLE
MSMEG_0839|M.smegmatis_MC2_155 VVLISAGREVGGGDKRCDVGALARIIDCQNLGANRYRLACVLGERIRVLQ
TH_0947|M.thermoresistible__bu VVLIAAGREVGGGDTRCDVGALARIVEYAEQPMGRYRLRCEVGERIRVLE
MAB_4165|M.abscessus_ATCC_1997 VVLIARGREVGGGDVRHDVGTAARVLDCESLGADRFAVRCEGAGRIRITR
****: *******: * *:*. ::: : . .*: : * . ***:
Mb0442|M.bovis_AF2122/97 WLPDDPYPRAKVRFWPDQPGHPVT-AAQLLEVEDRVVALFERIAAARGVR
Rv0434|M.tuberculosis_H37Rv WLPDDPYPRAKVRFWPDQPGHPVT-AAQLLEVEDRVVALFERIAAARGVR
MMAR_0751|M.marinum_M WLPDDPYPRATVQIWPDEPGAAVS-AAQFRDTEDRVMALFERIATARGIE
MUL_1383|M.ulcerans_Agy99 WLPDDPYPRATVQIWPDEPGAAVS-AAQFRDTEDRVMALFERIATARGIE
MAV_4720|M.avium_104 WLPDDPYPRATVMPWPDEPGAVVT-PEQLRGVEDRAVALFERIAQARGIT
Mflv_0170|M.gilvum_PYR-GCK WLPDDPYPRAVMQEWPDEPGGPVD-FAAIRDIEDRMVGLFERIATARGAQ
Mvan_0737|M.vanbaalenii_PYR-1 WLPDDPYPRAVVELWPDEPGQAVD-VEAIQDIEDRMVALFERIAAARGAQ
MSMEG_0839|M.smegmatis_MC2_155 WLDDAPYPRADIEPWPDEPGEPVE-ESEVAAVEERIVALFDLIGEASGKP
TH_0947|M.thermoresistible__bu WLPDDPYPRAVIEPWPDEPGEPVG-VDQLTELEDRMMALFERIAGAQGAE
MAB_4165|M.abscessus_ATCC_1997 WLEDDPYPRAEVEPWPDEPDERVLPLSALNEVQVRIENLLRRVATARQVR
** * ***** : ***:*. * . : * *: :. *
Mb0442|M.bovis_AF2122/97 LPAREVVLGYPVVDPA-DTGQRLYALACRVPMGPADRYAVLAAPSAADRL
Rv0434|M.tuberculosis_H37Rv LPAREVVLGYPVVDPA-DTGQRLYALACRVPMGPADRYAVLATPSAADRL
MMAR_0751|M.marinum_M LPDRDVVFDYQSDDIAADAGTLLYELASRVPMGPADGYAVLSARSAADRL
MUL_1383|M.ulcerans_Agy99 LPGRDVVFDYQSDDIAADAGTLLYELASRVPMGPADGYAVLSARSAADRL
MAV_4720|M.avium_104 LPGRDLLLGR--HDPERPPGQRLYELASRIPIGTADRYTVLCAPSAAERL
Mflv_0170|M.gilvum_PYR-GCK VNARD-IVHG--ADDSGDPAQWLYALTARLPMGQADRYAILAAPSVADRV
Mvan_0737|M.vanbaalenii_PYR-1 VNARD-IVAG--ADESGEAAKWLYALTARLPMGQADRYSVLAAPSAAERV
MSMEG_0839|M.smegmatis_MC2_155 VPSRD-IVAA--AG--LDPENRLYALAARVPMGQADRYSVLSAPTEAARL
TH_0947|M.thermoresistible__bu LPPRHHLLGE--PEPGQGVAERLYTLASRIPIGQADRYAVLAAPDPAARL
MAB_4165|M.abscessus_ATCC_1997 LPRRWSIATG----LPSGAEKRLYALASRVPMGQADRYAVLAAPTLEKRV
: * : ** *:.*:*:* ** *::*.: *:
Mb0442|M.bovis_AF2122/97 VRLGDALDSVAAMVEFELST-
Rv0434|M.tuberculosis_H37Rv VRLGDALDSVAAMVEFELST-
MMAR_0751|M.marinum_M AALAEAVDSVEAMVDFQLSD-
MUL_1383|M.ulcerans_Agy99 AALAEAVDSVEAMVDFQLSD-
MAV_4720|M.avium_104 AALREAVDAVTEVVEFQLSE-
Mflv_0170|M.gilvum_PYR-GCK AALSEAVDTVIAMVEFQLSE-
Mvan_0737|M.vanbaalenii_PYR-1 TALSEAVDTVTAMVEFQLSE-
MSMEG_0839|M.smegmatis_MC2_155 AALSEAVDTVTAMVEFQISE-
TH_0947|M.thermoresistible__bu AALREAVETVAAMVEFQLSQD
MAB_4165|M.abscessus_ATCC_1997 SALNDAVDTVNAMLDFRESDR
* :*:::* :::*. *