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VTTTPREDTNSRNTPPTRPITRLLALVRNTWRTLTSMGTALVLLFLLALAAIPGALLPQRSLNESKVAEY IAEHPTLGPWLDRVQAFDVFSSFWFTSIYVLLFVSLVGCLTPRLFEHFRSLRATPVPAPRNLSRLPKHHS ADVPCADVDAAATAVDGQLRGWRRTTRRDGEATEISAEKGYLREFGNIVFHFSLLGLLVAIAAGKLFSYE GNVIVIANGGPGFCTASPAAFDSFRAGNTVDGTSLYPMCIQVDDFDATYLDNGQAVGFQANIRYQADDDL TTGTWQPYLLKVNEPLRVGGDRVYLQGHGYAPTFTVTFPDGQTRTQTLQWRPDDQFTFLSSGAMRFDPPA GTYPDEDERRDNQIAIQGLFAPTALLHGALLSSRFPEMQDPAVAIDIYKGDTGLDTGRPQSVFSLDERMI GQGRLEKMARVNLKVGEDTRLADGTVVRFDGAEQFVNLQVSHDPAQIWVLVFSMTMMGGLLVSLIVRRRR VWVRLTPGPAGTVNVELGGLARTDNSGWGDEFERLTERLLTAVESATPAEKAKKADHS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0050 | - | - | 100% (549) | ResB family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0541 | - | 0.0 | 72.23% (515) | transmembrane protein |
| M. tuberculosis H37Rv | Rv0528 | - | 0.0 | 72.23% (515) | transmembrane protein |
| M. leprae Br4923 | MLBr_02410 | - | 0.0 | 71.37% (524) | hypothetical protein MLBr_02410 |
| M. abscessus ATCC 19977 | MAB_3974c | - | 0.0 | 71.37% (510) | putative cytochrome C biogenesis protein ResB |
| M. marinum M | MMAR_0874 | - | 0.0 | 71.48% (519) | ResB-family protein |
| M. avium 104 | MAV_4617 | - | 0.0 | 70.63% (538) | hypothetical protein MAV_4617 |
| M. smegmatis MC2 155 | MSMEG_0973 | - | 0.0 | 75.82% (550) | hypothetical protein MSMEG_0973 |
| M. thermoresistible (build 8) | TH_2249 | - | 0.0 | 77.37% (517) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_0627 | - | 0.0 | 70.05% (551) | ResB-family protein |
| M. vanbaalenii PYR-1 | Mvan_0868 | - | 0.0 | 83.81% (562) | ResB family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0541|M.bovis_AF2122/97 -----------------------------------MWRSLTSMGTALVLL
Rv0528|M.tuberculosis_H37Rv -----------------------------------MWRSLTSMGTALVLL
MMAR_0874|M.marinum_M ------------------------------------------MGTALVLL
MUL_0627|M.ulcerans_Agy99 --MSARADAESPKTARFGAILRLLG-----QKARNTWRSLTSMGTALVLL
MAV_4617|M.avium_104 ------------------MALATLR-----ATARNTWRALTSMGTALVLL
MLBr_02410|M.leprae_Br4923 ----------------MMQVLMRLL-----AWVRNTWRALTSMGTALVLL
Mflv_0050|M.gilvum_PYR-GCK MVTTTPREDTNSRNTPPTRPITRLL-----ALVRNTWRTLTSMGTALVLL
Mvan_0868|M.vanbaalenii_PYR-1 MVTTPEREDTNSRSKRPKRAISRLL-----ALIRNTWRTLTSMGTALVLL
TH_2249|M.thermoresistible__bu -----------------MSLTQRVR-----ALIRNTWRTLTSMGTALVLL
MSMEG_0973|M.smegmatis_MC2_155 -MTSSPRADTELPENPPDAAGLRVLGRRIWAPIRNTWRTLTSMGTALVLL
MAB_3974c|M.abscessus_ATCC_199 -----------------MTIAKRLL-----AYARNTWRGLTSMGTALALL
*****.**
Mb0541|M.bovis_AF2122/97 FLLALAAIPGALLPQRGLNAAKVDDYLAAHPLIGPWLDELQAFDVFSSFW
Rv0528|M.tuberculosis_H37Rv FLLALAAIPGALLPQRGLNAAKVDDYLAAHPLIGPWLDELQAFDVFSSFW
MMAR_0874|M.marinum_M FLLALGAIPGALVPQRSLNAGKVDDYLKAHPLIGPWLNKLQAFDVFSSFW
MUL_0627|M.ulcerans_Agy99 FLLALGAIPGALVPQRSLNAGKVDDYLKAHPLIGPWLNKLQAFDVFSSFW
MAV_4617|M.avium_104 FLLALGAIPGALLPQRNLNAGKVDDYLKAHPVIGPWLDRLQAFNVFSSFW
MLBr_02410|M.leprae_Br4923 FLLALGAIPGALLPQRDLNVGKVDDYVAAHPVIGSWLDQLQAFNVFSSVW
Mflv_0050|M.gilvum_PYR-GCK FLLALAAIPGALLPQRSLNESKVAEYIAEHPTLGPWLDRVQAFDVFSSFW
Mvan_0868|M.vanbaalenii_PYR-1 FLLALAAIPGALLPQRSLNESKVAEYISEHPTLGPWLDRLQAFDVFSSFW
TH_2249|M.thermoresistible__bu FLLALAAIPGALLPQRNLNEGKVAEYIAEHPTLGPWLDRLQAFDVFSSFW
MSMEG_0973|M.smegmatis_MC2_155 FLLALGAIPGALLPQRSLNESKVDEYLATHPTLGPWLDRLQAFDVFSSFW
MAB_3974c|M.abscessus_ATCC_199 VLLALGAIPGAMLPQRALNQAKVDEYLAEHSTIGPWLDRVQAFDVFSSFW
.****.*****::*** ** .** :*: *. :*.**:.:***:****.*
Mb0541|M.bovis_AF2122/97 FTAIYVLLFVSLVGCLAPRTIEHARSLRATPVAAPRNLARLPKHAHARLA
Rv0528|M.tuberculosis_H37Rv FTAIYVLLFVSLVGCLAPRTIEHARSLRATPVAAPRNLARLPKHAHARLA
MMAR_0874|M.marinum_M FTAIYVLLFVSLVGCLTPRMIEHARSLRATPVAAPRNLARLPKHAGSRVA
MUL_0627|M.ulcerans_Agy99 FTAIYVLLFVSLVGCLTPRMIEHARSLRATPVAAPRNLARLPKHAGSRVA
MAV_4617|M.avium_104 FTAIYVLLFVSLVGCLTPRMIEHVRSLRATPVAAPRNLARLPKYAGHRIA
MLBr_02410|M.leprae_Br4923 FTAIYTLLFVSLVGCLTPRMIEHARSLRAMPVIAPRNLARLPKHASFQVI
Mflv_0050|M.gilvum_PYR-GCK FTSIYVLLFVSLVGCLTPRLFEHFRSLRATPVPAPRNLSRLPKHHSADVP
Mvan_0868|M.vanbaalenii_PYR-1 FTAIYVLLFVSLVGCLTPRMVEHVRSLRATPVPAPRNLGRLPKHHSAEVS
TH_2249|M.thermoresistible__bu FTAIYVLLFVSLVGCLTPRTVDHVRSLRATPVPAPRNLSRLPKHHTADIA
MSMEG_0973|M.smegmatis_MC2_155 FTAIYVLLFISLVGCLTPRMIEHVRSLRAVPVAAPRNLGRLPKHHEAQVQ
MAB_3974c|M.abscessus_ATCC_199 FTAIYVLLFVSLVGCIIPRTVEHAKALRAQPVPVPRNLGRLPKHAERAVV
**:**.***:*****: ** .:* ::*** ** .****.****: :
Mb0541|M.bovis_AF2122/97 GEPA---ALAATITGRLRGWRSITRQQG----------DSVEVSAEKGYL
Rv0528|M.tuberculosis_H37Rv GEPA---ALAATITGRLRGWRSITRQQG----------DSVEVSAEKGYL
MMAR_0874|M.marinum_M GEPE---LLAATIVGRLRGWRTAIRRSG----------PTVEVSAEKGYL
MUL_0627|M.ulcerans_Agy99 GEPE---LLAATIVGRLWGWRTAIRRSG----------TTVEVSAEKGYL
MAV_4617|M.avium_104 ADAEDLNTLANTLVGRLRGWRTAIRHHDGAG------PDAVEVSAEKGYL
MLBr_02410|M.leprae_Br4923 GDDK---TLAGTIAGRLRGWRTVIRTQDG-V------VPETVVSAEKGYL
Mflv_0050|M.gilvum_PYR-GCK CADVD--AAATAVDGQLRGWRRTTRRDGEAT----------EISAEKGYL
Mvan_0868|M.vanbaalenii_PYR-1 GTDVA--AVAAAVDERLRGWRRTIRRGGDVAGAAPAATSGIEISAEKGYL
TH_2249|M.thermoresistible__bu G-EPR--PLAAEMTRRLRGWRTATREQDGVT----------EISAEKGYL
MSMEG_0973|M.smegmatis_MC2_155 A-DAA--ELAESVTQRLRGWRTVTRENVGVT----------EISAEKGYL
MAB_3974c|M.abscessus_ATCC_199 ADQG---QLAEAISGRLRGWRRSTREKDGIT----------EISAEKGYL
* : :* *** * :*******
Mb0541|M.bovis_AF2122/97 REFGNLVFHFALLGLLVAVAVGKLFGYEGNVIVIADGGPGFCSASPAAFD
Rv0528|M.tuberculosis_H37Rv REFGNLVFHFALLGLLVAVAVGKLFGYEGNVIVIADGGPGFCSASPAAFD
MMAR_0874|M.marinum_M REFGNLVFHFSLLGLLVAVAVGKLFGYEGNVIVIADGGPGFCSASPAAFD
MUL_0627|M.ulcerans_Agy99 REFGNLVFHFSLLGLLVAVAVGKLFGYEGNVIVIADGGPGFCSASPAAFD
MAV_4617|M.avium_104 REFGNLVFHFSLLGLLVAVAVGKLFGYEGNVIVIADGGPGFCSASPAAFD
MLBr_02410|M.leprae_Br4923 REFGNLVFHFSLLGLLVAVAVDKLFGYEGNVVVIADGGPGFCSASPAAFD
Mflv_0050|M.gilvum_PYR-GCK REFGNIVFHFSLLGLLVAIAAGKLFSYEGNVIVIANGGPGFCTASPAAFD
Mvan_0868|M.vanbaalenii_PYR-1 REFGNIVFHFSLLGLLVAIAAGKMFSYEGNVIVVADGGPGFCSASPAAFD
TH_2249|M.thermoresistible__bu REFGNIVFHFSLLGLLVAVAVGKMFGYEGQVIVVADGQPGFCSASPAAFD
MSMEG_0973|M.smegmatis_MC2_155 REFGNIVFHFSLLGLLVAVAAGKLFGYEGNVIVIADGGPGFCTASPAAFD
MAB_3974c|M.abscessus_ATCC_199 REFGNLVFHLSLVGLLVAFAVGKLFGYEGNVIVIADNGPGFCSSSPAAFD
*****:***::*:*****.*..*:*.***:*:*:*:. ****::******
Mb0541|M.bovis_AF2122/97 SFRAGNTVDGTSLHPICVRVNNFQAHYLPSGQATSFAADIDYQADPATAD
Rv0528|M.tuberculosis_H37Rv SFRAGNTVDGTSLHPICVRVNNFQAHYLPSGQATSFAADIDYQADPATAD
MMAR_0874|M.marinum_M SFRAGNTVDGTSLHPICIRVNDFAAHYLASGQATSFAADIAYQTG---ND
MUL_0627|M.ulcerans_Agy99 SFRAGNTVDGTSLHPICIRVNDFAAHYLASGQATSFAADIAYQTG---ND
MAV_4617|M.avium_104 SFRAGNTVDGTSLHPLCIRVDDFDAHYLPSGQAVSFAANIDYQSG---AD
MLBr_02410|M.leprae_Br4923 AFRAGNTVDGTSLHPICIRVNDFAAHYLPSGQAMSFTADIDYQDG---HD
Mflv_0050|M.gilvum_PYR-GCK SFRAGNTVDGTSLYPMCIQVDDFDATYLDNGQAVGFQANIRYQAD---DD
Mvan_0868|M.vanbaalenii_PYR-1 SFRAGNTVDGTSLYPMCVRVNDFEATYLENGQAVGFAANIDYQAG---DD
TH_2249|M.thermoresistible__bu SFRAGNTVDGTSLHPICLRVNGFDAEYLPSGQATSYAADIEYQAG---DD
MSMEG_0973|M.smegmatis_MC2_155 SFRAGNTVDGTSLHPMCIRVNNFDADYLPTGQALSFAADIDYQAG---DD
MAB_3974c|M.abscessus_ATCC_199 SFRAGNTVDGTNLDPVCVKVQDFKATYLASGQAHSFESNIQYQAG---DD
:**********.* *:*::*:.* * ** .*** .: ::* ** . *
Mb0541|M.bovis_AF2122/97 LIANSWRPYRLQVNHPLRVGGDRVYLQGHGYAPTFTVTFPDGQTRTSTVQ
Rv0528|M.tuberculosis_H37Rv LIANSWRPYRLQVNHPLRVGGDRVYLQGHGYAPTFTVTFPDGQTRTSTVQ
MMAR_0874|M.marinum_M LSANTWRPYRLAVNHPLRAGGDRVYLQGHGYAPTFTVTFPDGQTRTSTVQ
MUL_0627|M.ulcerans_Agy99 LSANTWRPYRLAVNHPLRAGGDRVYLQGHGYAPTFTVTFPDGQTRTSTVQ
MAV_4617|M.avium_104 LVANTWRHYRLQVNHPLRLGGDRVYLQGHGYAPTFSVTFPDGQIRTATVQ
MLBr_02410|M.leprae_Br4923 LTVNSWRPYRLEVNHPLRVAGNRVYLQGHGYAPTFTVTFPDGQTRTSTVQ
Mflv_0050|M.gilvum_PYR-GCK LTTGTWQPYLLKVNEPLRVGGDRVYLQGHGYAPTFTVTFPDGQTRTQTLQ
Mvan_0868|M.vanbaalenii_PYR-1 LTAGTWRPYLLKVNEPLRVGGDRVYLQGHGYAPTFTVTFPDGQTRTQTLQ
TH_2249|M.thermoresistible__bu LVTGTWRPYRLQVNHPLRVGGDRVYLQGHGYAPTFTVTFPDGQTRTQTLQ
MSMEG_0973|M.smegmatis_MC2_155 LSTDTWRPYRLEVNHPLRVGGDRVYLQGRGYAPSFTVTFPDGQTRSQTIQ
MAB_3974c|M.abscessus_ATCC_199 IQNNVWRPDRLAMNHPLRVNGNRVYLLGYGYAPTFTVTFPDGRKRSETIQ
: . *: * :*.*** *:**** * ****:*:******: *: *:*
Mb0541|M.bovis_AF2122/97 WRPDNPQTLLSAGVVRIDPPAGSYPNPDERRKHQIAIQGLLAPTEQLDGT
Rv0528|M.tuberculosis_H37Rv WRPDNPQTLLSAGVVRIDPPAGSYPNPDERRKHQIAIQGLLAPTEQLDGT
MMAR_0874|M.marinum_M WRPDNPQTLLSSGVARIDPPAGSYPTAAERRQHEIAIQGLLAPTEQLDGT
MUL_0627|M.ulcerans_Agy99 WRPDNPQTLLSSGVARIDPPAGSYPTAAERRQHEIAIQGLLAPTEQLDGT
MAV_4617|M.avium_104 WRPDNPQTLLSSGVVRIDPPAGSYPTAAERRQHEIAIQGLLAPTEQLDGT
MLBr_02410|M.leprae_Br4923 WRPENQQTLLSSGVVRIDPPAGSYPNMSERRQHEIAIQGLLAPTEQLDGT
Mflv_0050|M.gilvum_PYR-GCK WRPDDQFTFLSSGAMRFDPPAGTYPDEDERRDNQIAIQGLFAPTALLHGA
Mvan_0868|M.vanbaalenii_PYR-1 WRPEDQITFLSSGAMRFDPPGGTYSDERERRRNQIALQGLFAPTAQLDGT
TH_2249|M.thermoresistible__bu FRPDDMLTLLSSGVMRFDPPAGTYPDPDERRRNQIAIQGLFAPTAQFDGT
MSMEG_0973|M.smegmatis_MC2_155 WRPEEQITFLSSGVVRIDPPAGTYPDPDERRKHQIAIQGLFAPTKQLDGT
MAB_3974c|M.abscessus_ATCC_199 WRPDDPTTLLSSGAVRIDPPAGTYPDPNVRRKNQIAIQGLFAPTEQLHGT
:**:: *:**:*. *:***.*:*. ** ::**:***:*** :.*:
Mb0541|M.bovis_AF2122/97 LLSSRFPALNAPAVAIDIYRGDTGLDSGRPQSLFTLDHRLIEQGRLVKEK
Rv0528|M.tuberculosis_H37Rv LLSSRFPALNAPAVAIDIYRGDTGLDSGRPQSLFTLDHRLIEQGRLVKEK
MMAR_0874|M.marinum_M LLSSRFPALNAPAVAIDVYRGDTGLDTGRPQSLFSLDPRLIEQGRLVKEK
MUL_0627|M.ulcerans_Agy99 LLSSRFPALNAPAVAIDVYRGDTGLDTGRPQSLFSLDPRLIEQGRLVKEK
MAV_4617|M.avium_104 LLSSRFPALNAPAVAVDIYRGDTGLDTGRPQSLFTLDPRLIEQHRLTKEK
MLBr_02410|M.leprae_Br4923 LLLSRFPALNAPAVAIDIYRGDTGLDSGRPQSLFTLDPRLINQGRLTKEK
Mflv_0050|M.gilvum_PYR-GCK LLSSRFPEMQDPAVAIDIYKGDTGLDTGRPQSVFSLDERMIGQGRLEKMA
Mvan_0868|M.vanbaalenii_PYR-1 LLSSSFPELNDPAVAIDIYKGDTGLDTGRPQSLFTLDERMIGQGRLTKMA
TH_2249|M.thermoresistible__bu LMTSIFPELTDPAVAIDIYRGDTGLDSGRPQSLFTLDERLIEQNRLTKKA
MSMEG_0973|M.smegmatis_MC2_155 LLSSSFPALNDPAVAVDIYRGDTGLDTGRPQSLFSLDPRLIGQKRLTKVA
MAB_3974c|M.abscessus_ATCC_199 LLSSSFPEMRKPAVAINIYRGDTGLDSGRAQSIFDLDPRMIEQKRLNQVA
*: * ** : ****:::*:******:**.**:* ** *:* * ** :
Mb0541|M.bovis_AF2122/97 RVNLRAGQQVRIDQGPAAGTVVRFDGAVPFVNLQVSHDPGQSWVLVFAIT
Rv0528|M.tuberculosis_H37Rv RVNLRAGQQVRIDQGPAAGTVVRFDGAVPFVNLQVSHDPGQSWVLVFAIT
MMAR_0874|M.marinum_M RVNLRVGQQVRIDAGPAAGTIVRFDGAVPFVNLQVSHDPGQTWVLVFAIT
MUL_0627|M.ulcerans_Agy99 RVNLRVGQQVRIDAGPAAGTIVRFDGAVPFVNLQVSHDPGQTWVLVFAIT
MAV_4617|M.avium_104 RVNLRAGQAVRIDQGPAAGTVIRFDGAVPFVNLQVSHDPGQTWVLVFAVT
MLBr_02410|M.leprae_Br4923 RVNLQAGEQVRLGQGPGAGTVVRFDGAVPFVNLQVSHDPGQAWVFVFAIA
Mflv_0050|M.gilvum_PYR-GCK RVNLKVGEDTRLADG----TVVRFDGAEQFVNLQVSHDPAQIWVLVFSMT
Mvan_0868|M.vanbaalenii_PYR-1 RVNLKAGQDTRLEDG----TVVRFDGAVPFVNLQVSHDPAQIWVLVFSMT
TH_2249|M.thermoresistible__bu RVNLRLGEQTRLDDG----TTVRFDNAVPFINVQVSHDPAQVWVLVFALT
MSMEG_0973|M.smegmatis_MC2_155 RVNLEEGQETRLDDG----TVVRFDGAKPFVNLQVSHDPAQVWVLVFAMT
MAB_3974c|M.abscessus_ATCC_199 RANLLPGQSVKLNDG----TIVRFDGAVNFVNLQVSRDPAQLWVLIFALT
*.** *: .:: * * :***.* *:*:***:**.* **::*:::
Mb0541|M.bovis_AF2122/97 MMAGLLVSLLVRRRRVWARITPTTA---GTVNVELGGLTRTDNSGWGAEF
Rv0528|M.tuberculosis_H37Rv MMAGLLVSLLVRRRRVWARITPTTA---GTVNVELGGLTRTDNSGWGAEF
MMAR_0874|M.marinum_M MMAGLVVSLLVRRRRVWARLTPEND-APGTVNVELGGLARTDNSGWGDEF
MUL_0627|M.ulcerans_Agy99 MMAGLVVSLLVRRRRVWARLTPEND-APGTVNVELGGLARTDNSGWGDEF
MAV_4617|M.avium_104 MMAGLLVSLLVRRRRVWVRLTPDAGGAPGTVNVELGGLARTDNSGWGDEF
MLBr_02410|M.leprae_Br4923 MMVGLVVSLMVRRRRVWVRLTPAAG----TVNVELGGLARTDNSGWGDEF
Mflv_0050|M.gilvum_PYR-GCK MMGGLLVSLIVRRRRVWVRLTPGPA---GTVNVELGGLARTDNSGWGDEF
Mvan_0868|M.vanbaalenii_PYR-1 MMGGLLVSLVVRRRRVWVRLAPGAA---GTVNVELGGLARTDNSGWGDEF
TH_2249|M.thermoresistible__bu MMAGLLVSLVVRRHRVWVRISPSGP---GTVNVELGGLARTDNSGWGDEF
MSMEG_0973|M.smegmatis_MC2_155 MMAGLLVSLVVRRRRVWVRIEPAGA---GTVSVEFGGLARTDNSGWGDEF
MAB_3974c|M.abscessus_ATCC_199 MMAGLVVSLVIKRRRVWARLSPGAA--AGTVNVELGGLARTDSSGWGDEF
** **:***:::*:***.*: * **.**:***:***.**** **
Mb0541|M.bovis_AF2122/97 ERLTGRLLAGFEARSP---DMAEAAAGTGRDVD---
Rv0528|M.tuberculosis_H37Rv ERLTGRLLAGFEARSP---DMAEAAAGTGRDVD---
MMAR_0874|M.marinum_M ERLTERLLAGLGEPGTPDSAAAAAIRSSQVDVT---
MUL_0627|M.ulcerans_Agy99 ERLTERLLAGLGEPGTPDSAAAAAIRSSQVDVT---
MAV_4617|M.avium_104 ERLSQRLLDGLAEP-----ASRASQRSTEVDVK---
MLBr_02410|M.leprae_Br4923 ERLTERLLAGLVAADR---TLAAARRSSQMDVK---
Mflv_0050|M.gilvum_PYR-GCK ERLTERLLT---AVESATPAEK---AKKADHS----
Mvan_0868|M.vanbaalenii_PYR-1 ERLTARLLAGFDNTETAAPLQE---EKKADHS----
TH_2249|M.thermoresistible__bu ERLTERLLRSGSQTGPETGTATGADAATADPSREKV
MSMEG_0973|M.smegmatis_MC2_155 ERLTERLLEG--RTEATESAEE----KKA-------
MAB_3974c|M.abscessus_ATCC_199 ERLCDRCLEGFPPTG----AARAGNGHKDEDAE---
*** * * .